Title: $105 Cheap Flights to Mayesville, SC - Expedia.com

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# $105 Cheap Flights to Mayesville, SC

[View $105 flight on Sat, Jul 4, 2026](https://expedia.com/Flights-Search?trip=oneway&leg1=from:DCA,to:FLO,departure:7/4/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:104.20&airProductToken=AQpnCjEIwYIBEgQzMjYzGEMg4poBKNW9kQMwvL6RAzhCQABYAWoFQkFTSUNyCE9WQVhaTkJWCjIIwYIBEgQ1ODkzGOKaASDlciiqv5EDMOy_kQM4QkABWAFqBUJBU0lDcghPVkFYWk5CVhIMCAEQARgBKgJBQTIAGAEiBAgBEAEoAigDKAQwCw) 

[Mayesville Travel Guide](https://expedia.com/Mayesville.dx3000456025)[Hotels in Mayesville](https://expedia.com/Mayesville-Hotels.d3000456025.Travel-Guide-Hotels)[Car Rentals in Mayesville](https://expedia.com/Car-Rentals-In-Mayesville.d3000456025.Car-Rental-Guide)[Mayesville Vacation Packages](https://expedia.com/Mayesville.d3000456025.Destination-Travel-Guides)

## Popular airlines to Mayesville

- ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AA.svg)  
American Airlines  
[](https://www.expedia.com/Flights-Search?leg1=from:CMH,to:Mayesville, South Carolina, United States of America,departure:3/21/2026TANYT&leg2=from:Mayesville, South Carolina, United States of America,to:CMH,departure:3/28/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AA"}}])

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## How much is the cheapest flight to Mayesville?

Prices were available within the past 7 days and start at $105 for one-way flights and $229 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

All deals

One way

Roundtrip

![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif)

Sat, May 23 - Wed, May 27

DCA

Washington

FLO

Florence

$229

Roundtrip

found 1 day ago

[](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:DCA,to:FLO,departure:5/23/2026TANYT&leg2=from:FLO,to:DCA,departure:5/27/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:228.40&airProductToken=AQpnCjEIwYIBEgQyMTgyGEMg4poBKKbkjQMwkeWNAzhCQABYAWoFQkFTSUNyCE9WRldaTkJWCjIIwYIBEgQ1ODkzGOKaASDlcij35Y0DMLjmjQM4QkABWAFqBUJBU0lDcghPVkZXWk5CVgpnCjIIwYIBEgQ2MDA0GOVyIOKaASjBi44DMICMjgM4QkAAWAFqBUJBU0lDcghPVkZXWk5CVgoxCMGCARIEMTk3NxjimgEgQyjwjI4DMMmNjgM4QkABWAFqBUJBU0lDcghPVkZXWk5CVhIKCAEQARgBKgJBQRgBIgQIARABKAIoAygEMAs)

![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif)

Tue, Mar 31 - Tue, Apr 7

LGA

New York

FLO

Florence

$229

Roundtrip

found 4 days ago

[](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:LGA,to:FLO,departure:3/31/2026TANYT&leg2=from:FLO,to:LGA,departure:4/7/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:228.40&airProductToken=AQpoCjIIwYIBEgQxMzE3GMsBIOKaASj6jYkDMPeOiQM4QkAAWAFqBUJBU0lDcghPVkZXWk5CVgoyCMGCARIENTk4MxjimgEg5XIov4-JAzCBkIkDOEJAAVgBagVCQVNJQ3IIT1ZGV1pOQlYKaAoyCMGCARIENjAwMxjlciDimgEokt6JAzDX3okDOEJAAFgBagVCQVNJQ3IIT1ZGV1pOQlYKMgjBggESBDEwNjAY4poBIMsBKIzfiQMw_9-JAzhCQAFYAWoFQkFTSUNyCE9WRldaTkJWEgoIARABGAEqAkFBGAEiBAgBEAEoAigDKAQwCw)

![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif)

Wed, Mar 25 - Thu, Mar 26

JFK

New York

FLO

Florence

$249

Roundtrip

found 3 days ago

[](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:JFK,to:FLO,departure:3/25/2026TANYT&leg2=from:FLO,to:JFK,departure:3/26/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:248.39&airProductToken=AQpoCjIIwYIBEgQzMTk5GKlRIOKaASjDyYgDMMDKiAM4QkAAWAFqBUJBU0lDcghPVkFYWk5CVgoyCMGCARIENTk4MxjimgEg5XIonMyIAzDezIgDOEJAAVgBagVCQVNJQ3IIT1ZBWFpOQlYKaAoyCMGCARIENTgzOBjlciDimgEojNKIAzDP0ogDOEJAAFgBagVCQVNJQ3IIT1ZBWFpOQlYKMgjBggESBDMxOTkY4poBIKlRKL_TiAMwsNSIAzhCQAFYAWoFQkFTSUNyCE9WQVhaTkJWEgwIARABGAEqAkFBMgAYASIECAEQASgCKAMoBDAL)

![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif)

Wed, Mar 25 - Wed, Apr 1

EWR

New York

FLO

Florence

$249

Roundtrip

found 19 hours ago

[](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:EWR,to:FLO,departure:3/25/2026TANYT&leg2=from:FLO,to:EWR,departure:4/1/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:248.40&airProductToken=AQppCjMIwYIBEgQzMjA0GMSNASDimgEo2sqIAzDNy4gDOEJAAFgBagVCQVNJQ3IIT1VGV1pOQlYKMgjBggESBDU5ODMY4poBIOVyKJzMiAMw3syIAzhCQAFYAWoFQkFTSUNyCE9VRldaTkJWCmkKMgjBggESBDU5ODMY5XIg4poBKNybiQMwopyJAzhCQABYAWoFQkFTSUNyCE9WRldaTkJWCjMIwYIBEgQyNzk0GOKaASDEjQEo4pyJAzDWnYkDOEJAAVgBagVCQVNJQ3IIT1ZGV1pOQlYSCggBEAEYASoCQUEYASIECAEQASgCKAMoBDAL)

![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif)

Fri, May 15 - Tue, May 19

JFK

New York

FLO

Florence

$268

Roundtrip

found 6 days ago

[](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:JFK,to:FLO,departure:5/15/2026TANYT&leg2=from:FLO,to:JFK,departure:5/19/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:267.40&airProductToken=AQpoCjIIwYIBEgQzMTY3GKlRIOKaASihi40DMLCMjQM4QkAAWAFqBUJBU0lDcghPVkZXWk5CWAoyCMGCARIENTg5MxjimgEg5XIo5IyNAzCojY0DOEJAAVgBagVCQVNJQ3IIT1ZGV1pOQlgKZwoyCMGCARIENjAwMxjlciDimgEo0raNAzCXt40DOEJAAFgBagVCQVNJQ3IIT1ZGV1pOQlYKMQjBggESAzY1NxjimgEgqVEo2reNAzDYuI0DOEJAAVgBagVCQVNJQ3IIT1ZGV1pOQlYSCggBEAEYASoCQUEYASIECAEQASgCKAMoBDAL)

![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh)

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## Frequently asked questions

### What month is the cheapest to fly to Mayesville?

### Which US cities have the cheapest flights to Mayesville?

> - New Haven (HVN)
> - Beckley (BKW)
> - Wilmington (ILG, ILM)
> - Lewisburg (LWB)
> - Parkersburg (PKB)
> 
>   
> with prices usually starting around $37.

### Which US cities fly direct to Mayesville?

> - New York (JFK, LGA)
> - Newark (EWR)
> - Philadelphia (PHL)
> - Orlando (MCO)
> - Boston (BOS)
> 
>   
> To Charleston Intl. (CHS)
> - New York (JFK, LGA)
> - Newark (EWR)
> - Chicago (MDW, ORD)
> - Washington (DCA, IAD)
> - Philadelphia (PHL)
> 
>   
> To (MYR)
> - Newark (EWR)
> - New York (LGA)
> - Philadelphia (PHL)
> - Boston (BOS)
> - Chicago (MDW, ORD)

### How to find a cheap flight to Mayesville?

### Which airlines fly to Mayesville?

> - American Airlines
> - Delta
> - Delta Air Lines
> - Frontier Airlines
> - Spirit Airlines
> - United

### Where do you fly into Mayesville?

> - The closest major airport is Charlotte, NC (CLT-Charlotte-Douglas Intl.), about 99 miles from the city center, which is a hub for American Airlines, Delta, and United, with other airlines like Frontier Airlines, Spirit Airlines also operating here.
> - Charleston, SC (CHS-Charleston Intl.) is another option, about 77 miles away, serving as a hub for Delta, American Airlines, and United, with WN, JetBlue Airways also operating here.
> - Myrtle Beach, SC (MYR-Myrtle Beach Intl.), about 91 miles away, serving as a hub for American Airlines, Delta, and WN, with United, Spirit Airlines also operating here.
> - Columbia, SC (CAE-Columbia Metropolitan), about 63 miles away, serving as a hub for Delta, American Airlines, and United, with Alaska Airlines, Aeromexico also operating here.
> - Florence, SC (FLO-Florence Regional), about 36 miles away, serving as a hub for American Airlines.

### What is the cheapest airport to fly to in Mayesville?

### Which budget airlines fly to Mayesville?

> - Spirit Airlines: serves Columbia (CAE), North Myrtle Beach (MYR), Charleston (CHS), Charlotte (CLT)
> - Southwest Airlines: serves North Myrtle Beach (MYR), Charleston (CHS), Charlotte (CLT)
> - Frontier Airlines: serves North Myrtle Beach (MYR), Charleston (CHS), Charlotte (CLT)
> - Breeze: serves North Myrtle Beach (MYR), Charleston (CHS)
> - JetBlue Airways: flies to Charleston (CHS)
> - WestJet: serves Columbia (CAE), North Myrtle Beach (MYR), Charleston (CHS), Charlotte (CLT)
> - Volaris: flies to Charlotte (CLT)
> - Sun Country Airlines: serves North Myrtle Beach (MYR), Charleston (CHS), Charlotte (CLT)
> - GOL Linhas Aereas Inteligentes: serves Charleston (CHS), Charlotte (CLT)
> - GOL Linhas Aereas S.A.: serves Charleston (CHS), Charlotte (CLT)

### What is the best month to visit Mayesville?

### How far in advance should I book a flight to Mayesville?

### What day of the week is cheapest day to buy a plane ticket to Mayesville?

### What is the most expensive month to fly to Mayesville?

### How can I track flight prices to Mayesville?

### How to get a cheap last-minute flight to Mayesville?

### Can I earn miles booking a flight to Mayesville with Expedia?

### Can I save money by booking a Mayesville trip package?

### Can I change or cancel my flight to Mayesville?

\*Flight schedules are subject to change.

## Book with confidence

# Tips to find the cheapest flights to Mayesville

**The cheapest day to fly**

Get started finding a cheap flight to Mayesville on Expedia by either choosing a deal on this page or entering into the search bar your travel dates, origin airport, and whether you want roundtrip or one-way airfare. You can filter for flexibility, number of stops, airline, and departure/arrival times to find the best flight for you.

**The cheapest month to fly**

May is the cheapest month to fly to Mayesville. This coincides with the low season when fewer people travel. Whichever month you travel in, though, be sure to book at least a month in advance if you want to score cheap tickets to Mayesville. ARC's data shows that domestic flights booked 28 days or more before departure are typically 24% cheaper than those booked last minute. 

**The most affordable time to book a flight**

Typically, a Sunday can be the cheapest time to book a flight to Mayesville, according to ARC’s data. On average, you could save between 6% and 13% by booking on a Sunday instead of a Friday, which is the most expensive day to make a reservation. 

**The cheapest round-trip tickets to Mayesville**

The lowest price for round-trip flights to Mayesville in 2026 starts from from $229, while one-way tickets start from from $105\. Expedia's effective search tool is one of the best ways to find a budget airfare. Simply enter your dates, and within seconds, it'll show you a vast selection of the cheapest flights to Mayesville. If you have a preferred departure time or airline, you can use the handy filters to customize your search.

**The cheapest airlines flying to Mayesville**

American Airlines are just some of the airlines that can typically offer cheap tickets to Mayesville. You can find their most affordable flights by using the “airline” search filter and then sorting prices from low to high. As a trusted partner of the world's leading airlines, Expedia offers you some of the best airfare deals to Mayesville and countless more destinations worldwide.

**The most affordable airports to fly into**

To view the cheapest airports to fly into for Mayesville, simply order your search results from lowest to highest price. Expedia's search tool compares flight prices for all airports close to your destination, so you don't have to manually search them one by one to find the cheapest flight to Mayesville. If you have a preferred place to fly into, take advantage of the “arrival airport” filter to narrow down your search on Expedia.

**Save with a package**

With Expedia's amazing [package deals](https://www.expedia.com/package-deals), you could save hundreds of dollars by booking your Mayesville plane tickets together with your accommodations, car rental, or activities. Just select the search wizard's “package” option to view some of the cheapest deals. Look out for the green savings label to see how much you're saving. 

**Date flexibility for the cheapest flights to Mayesville**

If you can be flexible with your travel dates, it's a good idea to broaden your search by comparing prices on different days. This will open up more options, meaning you could uncover a less expensive flight to Mayesville. 

**Stopover savings**

The cheapest tickets to Mayesville are sometimes those with a stopover. Book one of these flights, and you'll change planes at an airport en route to Mayesville. While the overall travel time might be longer than a non-stop flight, you may decide it's worth it for the money saved.

**Get Expedia's Price Drop Protection**

Price Drop Protection means that if your flight gets cheaper after booking, you'll be credited the difference\*. This gives you peace of mind that you're getting one of the cheapest flights to Mayesville for your chosen departure. Expedia's Price Drop Protection is available for a small fee but is free to One Key Gold and Platinum tier members.

\*Terms apply.

**Use our Price Tracking feature**

Expedia's Price Tracking feature is another great tool that removes the guesswork from finding cheap flights to Mayesville. Simply download the free Expedia app to your smart device and activate Mayesville flight price alerts for your travel dates. There's even a price predictor tool that uses historical data to indicate the best time to book, giving you peace of mind that you'll nab the lowest prices.

**Book with Expedia**

As well as Price Drop Protection and Price Tracking, Expedia's close partnership with a vast selection of the world's leading airlines means you're sure to find cheap flights to Mayesville. Plus, the One Key rewards program lets you earn real cash rewards on most bookings that you can use to save money on future trips. Best of all, it's free to join, and members often unlock exclusive discounts, too.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023\. The percentages you see are averages. 

## Travel information

| Destination airport           | Florence Regional |
| ----------------------------- | ----------------- |
| Destination airport IATA code | FLO               |
| Destination city name         | Florence          |
| Roundtrip price               | $228              |

## Trending flights to Mayesville

Prices were available within the past 7 days and start at $105 for one-way flights and $229 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

All deals

One way

Roundtrip

![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif)

Sat, May 23 - Wed, May 27

DCA

Washington

FLO

Florence

$229

Roundtrip

found 1 day ago

[](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:DCA,to:FLO,departure:5/23/2026TANYT&leg2=from:FLO,to:DCA,departure:5/27/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:228.40&airProductToken=AQpnCjEIwYIBEgQyMTgyGEMg4poBKKbkjQMwkeWNAzhCQABYAWoFQkFTSUNyCE9WRldaTkJWCjIIwYIBEgQ1ODkzGOKaASDlcij35Y0DMLjmjQM4QkABWAFqBUJBU0lDcghPVkZXWk5CVgpnCjIIwYIBEgQ2MDA0GOVyIOKaASjBi44DMICMjgM4QkAAWAFqBUJBU0lDcghPVkZXWk5CVgoxCMGCARIEMTk3NxjimgEgQyjwjI4DMMmNjgM4QkABWAFqBUJBU0lDcghPVkZXWk5CVhIKCAEQARgBKgJBQRgBIgQIARABKAIoAygEMAs)

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- [Flights from Gulfport (GPT) to Sumter (SUM) ](https://www.expedia.com/lp/flights/gpt/sum/gulfport-to-sumter)
- [Flights from Rochester (RST) to Sumter (SUM) ](https://www.expedia.com/lp/flights/rst/sum/rochester-to-sumter)
- [Flights from Elmira (ELM) to Sumter (SUM) ](https://www.expedia.com/lp/flights/elm/sum/elmira-to-sumter)
- [Flights from Flint (FNT) to Sumter (SUM) ](https://www.expedia.com/lp/flights/fnt/sum/flint-to-sumter)
- [Flights from Dallas (DAL) to Sumter (SUM) ](https://www.expedia.com/lp/flights/dal/sum/dallas-to-sumter)
- [Flights from Cleveland (CLE) to Sumter (SUM) ](https://www.expedia.com/lp/flights/cle/sum/cleveland-to-sumter)
- [Flights from Albany (ALB) to Sumter (SUM) ](https://www.expedia.com/lp/flights/alb/sum/albany-to-sumter)

- [Crystal Lakes Golf Course ](https://www.expedia.com/Crystal-Lakes-Golf-Course-Sumter.d553248621560493196.Vacation-Attraction)
- [Visit Gable ](https://www.expedia.com/Gable.dx6133784)
- [O'donnell House ](https://www.expedia.com/ODonnell-House-Sumter.d553248621560493195.Vacation-Attraction)
- [Visit Sumter ](https://www.expedia.com/Sumter.dx6058099)

- [Car rentals near Oswego ](https://www.expedia.com/Car-Rentals-In-Oswego.d553248634998916890.Car-Rental-Guide)
- [Car rentals near East Sumter ](https://www.expedia.com/Car-Rentals-In-East-Sumter.d553248634999359699.Car-Rental-Guide)
- [Car rentals near Mulberry ](https://www.expedia.com/Car-Rentals-In-Mulberry.d553248634999253615.Car-Rental-Guide)
- [Car rentals near Sumter ](https://www.expedia.com/Car-Rentals-In-Sumter.d6058099.Car-Rental-Guide)
- [Car rentals near Gable ](https://www.expedia.com/Car-Rentals-In-Gable.d6133784.Car-Rental-Guide)
- [Enterprise Rental Cars in Sumter ](https://www.expedia.com/Enterprise-Car-Rentals-In-Sumter.d6058099-c15.Car-Rental-Guide-Suppliers)
- [Car rental Sumter Airport (SUM) ](https://www.expedia.com/Car-Rentals-In-Sumter-Municipal.d6032139.Car-Rental-Guide)
- [Car rentals near Dillion Park ](https://www.expedia.com/Car-Rentals-In-Dillion-Park.d553248621560493197.Car-Rental-Guide)
- [Budget Rental Cars in Sumter ](https://www.expedia.com/Budget-Car-Rentals-In-Sumter.d6058099-c39.Car-Rental-Guide-Suppliers)
- [Hertz Rental Cars in Sumter ](https://www.expedia.com/Hertz-Car-Rentals-In-Sumter.d6058099-c40.Car-Rental-Guide-Suppliers)

- [Sumter Vacation Rentals ](https://www.expedia.com/Sumter-Vacation-Rentals.d6058099.Travel-Guide-VacationRentals)

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