Photo by Caroline Nunez

Find hotels in Mayesville, SC from $52

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Our top choices for Mayesville hotels

1. Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
2.0 star property
Florence
8.6 out of 10, Excellent, (2,757 reviews)
"Quiet clean and inexpensive stay, especially relative to neighboring locations"
United States
Carl
$65 nightly
The price is $72
Nov 9 - Nov 10
Total with taxes and fees
Howard Johnson by Wyndham Florence

2. Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
2.5 star property
Florence
9.0 out of 10, Wonderful, (2,499 reviews)
"Great place to spend the night during our road trip. Would stay again."
United States
Susan
$90 nightly
The price is $101
Nov 15 - Nov 16
Total with taxes and fees
Park Inn by Radisson Florence, SC

3. Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
2.5 star property
Florence
9.0 out of 10, Wonderful, (1,389 reviews)
"Comfortable beds and clean environments."
United States
Steven
$101 nightly
The price is $113
Nov 29 - Nov 30
Total with taxes and fees
Comfort Inn & Suites Florence Center Area

4. Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
2.5 star property
Florence
8.4 out of 10, Very good, (423 reviews)
"Nice spot for an overnight!"
United States
Sharhonda
$89 nightly
The price is $100
Nov 15 - Nov 16
Total with taxes and fees
Quality Inn & Suites Florence Civic Center

5. Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
2.5 star property
Florence
8.4 out of 10, Very good, (356 reviews)
"Great staff easy Check in I love staying here!!!"
United States
Alanya
$102 nightly
The price is $114
Nov 17 - Nov 18
Total with taxes and fees
Spark by Hilton Florence North I-95, SC

6. Courtyard by Marriott Florence

Courtyard by Marriott Florence
3.0 star property
Florence
7.8 out of 10, Good, (773 reviews)
"Great place to stay!!!"
United States
Willie
$111 nightly
The price is $124
Nov 15 - Nov 16
Total with taxes and fees
Courtyard by Marriott Florence

7. Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
3.0 star property
Florence
9.0 out of 10, Wonderful, (1,002 reviews)
"The room was clean and the breakfast was good"
United States
Ana Maria
$116 nightly
The price is $130
Nov 15 - Nov 16
Total with taxes and fees
Hyatt Place Florence Downtown

8. 1912 Bed and Breakfast

1912 Bed and Breakfast
3.5 star property
Sumter
10.0 out of 10, Exceptional, (335 reviews)
"We enjoyed our stay. The room we stayed in was very nice and comfortable. The breakfast was good as well. We would definitely stay there again if we are in the area."
United States
Laura
$141 nightly
The price is $141
Nov 11 - Nov 12
Total with taxes and fees
1912 Bed and Breakfast

9. SpringHill Suites by Marriott Florence

SpringHill Suites by Marriott Florence
3.0 star property
Florence
8.2 out of 10, Very good, (1,002 reviews)
"Staff is so helpful hotel is very clean well kept"
United States
Tom
$108 nightly
The price is $121
Nov 11 - Nov 12
Total with taxes and fees
SpringHill Suites by Marriott Florence

10. Hyatt Place Sumter / Downtown

Hyatt Place Sumter / Downtown
3.0 star property
Sumter
9.2 out of 10, Wonderful, (986 reviews)
"Second time staying here. Best hotel in Sumter. Friendly staff, great location."
United States
Carlos
$143 nightly
The price is $160
Nov 23 - Nov 24
Total with taxes and fees
Hyatt Place Sumter / Downtown

11. Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG
3.0 star property
Florence
9.4 out of 10, Exceptional, (1,002 reviews)
"Great stay great breakfast clean"
United States
Zachary
$122 nightly
The price is $137
Dec 6 - Dec 7
Total with taxes and fees
Staybridge Suites Florence - Civic Center by IHG

12. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
2.5 star property
Florence
9.0 out of 10, Wonderful, (1,002 reviews)
"Nice and clean hotel"
United States
HANH
$114 nightly
The price is $128
Nov 22 - Nov 23
Total with taxes and fees
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

13. Tru by Hilton Florence I-95

Tru by Hilton Florence I-95
2.5 star property
Florence
8.6 out of 10, Excellent, (1,002 reviews)
"Great hotel and staff"
United States
Margarita
$115 nightly
The price is $129
Nov 17 - Nov 18
Total with taxes and fees
Tru by Hilton Florence I-95

14. TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence
3.0 star property
Florence
9.0 out of 10, Wonderful, (925 reviews)
"Fabulous pet-friendly place to stay."
United States
Ralph
$110 nightly
The price is $123
Nov 9 - Nov 10
Total with taxes and fees
TownePlace Suites by Marriott Florence

15. La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence
3.0 star property
Florence
7.8 out of 10, Good, (1,456 reviews)
"Close to the restaurants and shopping."
United States
Brenda
$89 nightly
The price is $100
Nov 22 - Nov 23
Total with taxes and fees
La Quinta Inn & Suites by Wyndham Florence

16. Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center
2.5 star property
Florence
9.0 out of 10, Wonderful, (1,002 reviews)
"Good location, clean room and good breakfast."
United States
NOORUDIN
$114 nightly
The price is $128
Nov 22 - Nov 23
Total with taxes and fees
Hampton Inn & Suites Florence Center

17. Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95
2.5 star property
Florence
9.0 out of 10, Wonderful, (1,001 reviews)
"Excellente hotel, clean, good breakfast, and quiet."
Canada
chantal
$114 nightly
The price is $128
Nov 18 - Nov 19
Total with taxes and fees
Hampton Inn & Suites Florence-North-I-95

18. Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center
2.5 star property
Florence
7.4 out of 10, Good, (1,011 reviews)
"Good rooms for the price"
United States
Louis
$66 nightly
The price is $74
Dec 2 - Dec 3
Total with taxes and fees
Days Inn by Wyndham Florence Near Civic Center

19. Comfort Suites Florence I-95

Comfort Suites Florence I-95
2.5 star property
Florence
8.2 out of 10, Very good, (1,001 reviews)
"Our room was very clean and quiet. The staff was excellent and the breakfast was very good. They did charge us a $5.95 fee for the use of the amenities, gym, pool and breakfast located at the property."
United States
Michael
$120 nightly
The price is $134
Dec 1 - Dec 2
Total with taxes and fees
Comfort Suites Florence I-95

20. Aloft by Marriott Florence

Aloft by Marriott Florence
3.0 star property
Florence
8.4 out of 10, Very good, (402 reviews)
"Excellent stay"
United States
Darlene
$101 nightly
The price is $113
Nov 15 - Nov 16
Total with taxes and fees
Aloft by Marriott Florence
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay near Mayesville

Discover the charm of Mayesville, a small town in Sumter County, South Carolina. Enjoy outdoor adventures and family-friendly activities amidst the scenic beauty of SC land. With friendly locals and a welcoming atmosphere, you’ll create unforgettable memories exploring nearby attractions and enjoying the great outdoors.

Sumter

For travelers seeking a blend of outdoor adventure and rich history, Sumter is a charming destination that offers serene landscapes and engaging attractions. Explore the stunning Swan Lake Iris Gardens, delve into the past at the historic O'Donnell House, or enjoy the vibrant atmosphere around Morris College. Located about 9 miles by car from Mayesville, Sumter is an ideal choice for a weekend getaway, blending convenience with a variety of experiences. It’s a smart pick for your next stay!

Oswego

Plan your stay in Oswego, a top-rated choice for travelers seeking a blend of business, family, and nature experiences. This charming village is conveniently located near attractions such as the Swan Lake Iris Gardens and the historic O'Donnell House, making it an ideal base for exploration. With popular activities including motor racing at the nearby racetrack and stadium, Oswego offers plenty of excitement year-round. At around 5 miles from Mayesville, it’s a smart choice for your vacation getaway.

Gable

If you are a traveler seeking a blend of business, family fun, and outdoor adventures, look no further than Gable, known for its scenic beauty and vibrant activities. Enjoy the recreational opportunities at Woods Bay State Park, explore the historic charm of the O'Donnell House, and immerse yourself in the academic atmosphere of Morris College. Gable is located about 9 miles from Mayesville, making it a smart choice for your stay, whether you're here for leisure or work.

East Sumter

Immerse yourself in East Sumter, where travelers interested in culture and entertainment can easily access attractions like the beautiful Swan Lake Iris Gardens and the historic O'Donnell House. This welcoming village is about 7 miles from Mayesville, making it a great base for exploring local landmarks and enjoying family-friendly activities. With its blend of charm and accessibility, East Sumter is a smart choice for your next vacation stay.

Mulberry

Travelers seeking a charming getaway will find Mulberry to be the perfect base for their vacation, featuring serene landscapes and a welcoming atmosphere. This quaint village offers unique experiences, from exploring the historic O'Donnell House to enjoying the natural beauty at Riley Field and the vibrant community at Morris College. Situated about 7 miles from Mayesville, Mulberry provides easy access to local attractions while maintaining a peaceful retreat. Choosing Mulberry for your stay ensures a delightful blend of relaxation and adventure.

Stay near popular Mayesville attractions

Discover the charm of Mayesville, where family-friendly adventures await! With beautiful parks and lush botanical gardens, this destination offers the perfect blend of outdoor fun and urban exploration, making it an ideal spot for travelers seeking relaxation and memorable experiences.

Learn more about Mayesville

Venture to Crystal Lakes Golf Course and Sumter Mall—just two of the sights around Mayesville.

A sunflower in a field with a dirt path and trees in the background.
Photo by Caroline Nunez
Open Photo by Caroline Nunez

Top Mayesville Hotel Reviews

Find out more about Mayesville

Top reasons to visit Mayesville

  • Charming Outdoor Spaces: Mayesville features a variety of scenic parks and botanical gardens perfect for leisurely strolls and picnics.
  • Family-Friendly Activities: Enjoy recreational areas and community events, making it ideal for family vacations.
  • Rich Local Culture: Engage with the community through Sunday school and local learning centers.
  • Romantic Getaways: The quaint atmosphere and beautiful landscapes provide a perfect setting for couples.
  • Comfortable Accommodations: A range of budget-friendly hotels and pet-friendly options cater to diverse travelers.

Find great hotels near Mayesville

Discover a variety of comfortable and budget-friendly hotel options in Mayesville, South Carolina, ranging from 2 to 3.5 stars. Whether you're seeking pet-friendly accommodations or a welcoming environment for LGBTQIA travelers, you're sure to find the perfect place to stay. Mayesville also offers a selection of homes and house information for those looking to explore longer-term options. Enjoy your visit with a stay that meets all your needs!

  • Hyatt Place Sumter / Downtown: Experience a blend of business and leisure at Hyatt Place Sumter / Downtown, located 9 miles from Mayesville. This 3-star hotel is ideal for travelers seeking a pet-friendly environment while on business trips. With amenities like a 24-hour Business Center, Conference Space, and Meeting Rooms, it caters to the needs of professionals. Enjoy the convenience of bringing your furry friends along, as pets are permitted on the premises, making your stay both productive and enjoyable.
  • Sleep Inn Sumter: Situated 11 miles from Mayesville, Sleep Inn Sumter is designed for comfort and convenience. Guests can indulge in a complimentary buffet breakfast to start the day off right. For entertainment, the hotel offers Satellite TV and Pay Movies, ensuring you stay entertained during your downtime. Its prime location near the City Center adds an extra layer of appeal, allowing guests to explore local attractions with ease.
  • Tru by Hilton Sumter: Just 11 miles from Mayesville, Tru by Hilton Sumter caters to travelers looking for a modern and pet-friendly stay. With a welcoming atmosphere, the hotel allows pets for a variable fee, making it a great choice for those traveling with dogs or cats. Guests can enjoy stylish, vibrant spaces and easy access to local attractions, making it a fantastic option for both leisure and business travelers seeking a lively and accommodating environment.

Where to stay near Mayesville

Mayesville, South Carolina, offers a charming escape for outdoor enthusiasts and families alike. Explore the friendly vibe of this small town while enjoying nearby attractions like the scenic parks and historical sites of Sumter County. Take leisurely strolls through lush landscapes or plan romantic picnics under the wide Southern skies. With its welcoming atmosphere and rich local culture, Mayesville is the perfect base for discovering the beauty and warmth of South Carolina.

  • Sumter: Located 9 miles from Mayesville, Sumter is a vibrant city known for its outdoor activities and scenic beauty. Visitors can enjoy a range of family-friendly experiences, from exploring recreational areas to shopping at local malls and centers. Notable attractions include picturesque lakes and the beautiful national parks nearby, making it a perfect destination for nature lovers. The peak travel months are March to April and July, so plan your visit during this time to enjoy the bustling atmosphere and local events.
  • Oswego: Just 5 miles from Mayesville, Oswego is a charming village that offers a quaint escape from the hustle and bustle. While the traveler arrivals remain steady throughout the year, spring and summer (March to April and July) bring a slight uptick in visitors. Oswego is perfect for those looking to unwind in a peaceful setting, with opportunities to connect with the local community and enjoy the serene landscapes that characterize this picturesque area.
  • East Sumter: Situated 7 miles away from Mayesville, East Sumter is a delightful village that attracts travelers seeking a beach experience. Although visitor numbers peak mainly from March to April and July, the area is welcoming year-round. With its close proximity to beautiful beaches, East Sumter allows for a perfect day of sunbathing and relaxation. It’s a great spot to enjoy the coastal charm while soaking up the Southern hospitality that this region is known for.

Things to do near Mayesville

Mayesville offers a charming setting for outdoor, family, and romantic vacations. Visitors can enjoy various activities, including a recreational area, boardwalk, and shopping mall center. Additionally, there are opportunities for community engagement through Sunday school and a learning center, making it a perfect destination for those looking to relax and explore local culture.

Shopping

The nearest shopping destination is Pocalla Crossing Shopping Center, located 12 miles away, offering a variety of family-friendly shops. If you're up for a drive, head to Sumter Mall, 10 miles away, or venture further to Magnolia Mall, 26 miles away, both featuring diverse shopping experiences.

Recreation

Crystal Lakes Golf Course, located 9 miles from Mayesville, offers a refreshing outdoor experience with scenic views and a challenging course. Palmetto Tennis Center, 10 miles away, provides a vibrant atmosphere for tennis enthusiasts. Dillion Park, 9 miles from town, invites relaxation with its serene walking paths and tranquil settings.

Adventure

Experience thrilling races at Florence Motor Speedway, located 20 miles from Mayesville, where adrenaline and speed collide. For family fun, visit Neptune Island Waterpark, 26 miles away, offering exciting slides and attractions. Don't miss the iconic Darlington Raceway, 27 miles from Mayesville, for heart-pounding motorsport action.

Nightlife

For a movie night, visit Regal Swamp Fox, just 25 miles from Mayesville, offering a cozy, romantic atmosphere. Alternatively, enjoy a show at Center Theatre, located 28 miles away, where you can immerse yourself in culture and entertainment with family and friends.

Booking tips and Expedia advantages for Mayesville

To save money during your visit to Mayesville, plan your trip between December and February for lower accommodation rates, with Mondays being the cheapest stay. Utilize Expedia to find eco-friendly hotels and sort options by price. Consider booking a package deal that combines flights, hotels, and activities for additional savings. Join Expedia's One Key membership for exclusive discounts and earn OneKeyCash for future stays. Look out for special sales and promotions to maximize your savings while enjoying the local attractions.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Mayesville are December to February, where the prices are slightly lower. This is in comparison to April to May and September, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Mayesville is Monday. The most expensive day to stay in Mayesville is Saturday.
  • Find cheap hotels on Expedia: Utilize Expedia’s search tool to refine your travel preferences, such as your budget, desired location, and the type of hotel you’re looking for. For instance, selecting the "Eco-certified" option will showcase sustainable and environmentally-friendly hotels that are currently available. To find the best prices and deals, simply sort the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by combining your Mayesville hotel reservation with your flights and activities through an Expedia package deal.
  • Become a One Key member: Join Expedia's One Key membership program for exclusive discounts and deals on hotel bookings. You can also earn OneKeyCash to use on future selected hotels.

Find the best attractions near Mayesville

Mayesville, South Carolina, offers a delightful mix of outdoor adventures and family-friendly activities, making it perfect for romantic getaways too. Visitors can explore local attractions such as urban parks, botanical gardens, and charming parks that provide a city experience while enjoying nature. This quaint town caters to those seeking both relaxation and exploration, ensuring a memorable vacation for travelers of all types.

  • Swan Lake Iris Gardens: Experience the tranquil beauty of this botanical garden, located 10 miles from Mayesville. With its stunning array of irises and serene walking paths, it's perfect for family outings, romantic strolls, or simply enjoying nature's artistry.
  • O'Donnell House: Immerse yourself in the rich history and culture of the region at O'Donnell House, situated 9 miles away. This historic house showcases architectural charm and offers a glimpse into local heritage, making it a must-see for history enthusiasts.
  • Sumter County Gallery of Art: Just 9 miles from Mayesville, the Sumter County Gallery of Art features diverse exhibitions that celebrate local artists and culture. The gallery provides an inspiring space to appreciate creativity and engage with the arts.

Best time to go to Mayesville

Visitor numbers in Mayesville is generally unchanged in popularity throughout the year. The best time to visit Mayesville is dependant on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are slightly high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are slightly low and weather is mostly sunny with light rain.

Calendar MonthTemperaturePrecipitationCloudinessOccupancyPricing
January45.9°F (7.7°C)Light RainMostly SunnySlightly LowSlightly Low
February49.8°F (9.9°C)Light RainMostly SunnySlightly LowSlightly Low
March55.8°F (13.2°C)Light RainMostly SunnySlightly HighAverage
April63.7°F (17.6°C)Light RainMostly SunnyAverageSlightly High
May71.4°F (21.9°C)Light RainMostly SunnyAverageSlightly High
June78.4°F (25.8°C)Light RainMostly SunnyAverageAverage
July81.3°F (27.4°C)Light RainMostly SunnySlightly HighAverage
August79.7°F (26.5°C)Light RainMostly SunnySlightly HighAverage
September75.0°F (23.9°C)Light RainMostly SunnyAverageSlightly High
October65.3°F (18.5°C)Light RainMostly SunnySlightly LowAverage
November54.9°F (12.7°C)Light RainMostly SunnyAverageAverage
December49.8°F (9.9°C)Light RainMostly SunnyAverageSlightly Low

The nearest major airports for your trip to Mayesville

To visit Mayesville, South Carolina, you can fly into two major airports. Columbia Metropolitan Airport (CAE) is located 53 miles away, with nearby hotel options like the 4-star Graduate by Hilton, 7 miles from the airport, and the Doubletree by Hilton, 6 miles away. Florence Regional Airport (FLO) is closer at 31 miles from Mayesville, offering hotel choices such as the 3.5-star TownePlace Suites by Marriott, 6 miles from the airport, and the 3-star Hotel Florence, just 2 miles away. Both airports provide convenient access to Mayesville and comfortable accommodations nearby.

Frequently Asked Questions

What is the best area to stay in Mayesville?

The best area to stay in Mayesville, South Carolina, is in the surrounding Sumter area, particularly near the intersection of US-378 and US-76/US-301, as Mayesville itself is a very small town with limited accommodation options.

This area of Sumter provides convenient access to Mayesville, which is just a short drive east. You'll find a selection of hotels and amenities along the main thoroughfares, making it easy to reach local points of interest. It's a practical base for exploring the region.

For solo travelers or couples looking for convenience and a relaxed stay, hotels in this Sumter corridor are ideal.

When is the best time to go to Mayesville?

For the most pleasant weather and to enjoy outdoor activities, the best times to visit Mayesville are during the spring (April to early June) and fall (late September to early November).

During these seasons, Mayesville experiences mild temperatures and lower humidity, making it ideal for exploring the area's natural beauty and historic sites. Spring brings blooming dogwoods and azaleas, while fall offers comfortable temperatures and colorful foliage.

Can I cancel my hotel reservation on Expedia?

You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Mayesville.

How much is the nightly rate at a Mayesville hotel?

Prices for hotels in Mayesville often vary, but you can find a great deal from $52 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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