Photo by Caroline Nunez

Find hotels in Mayesville, SC from $65

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Our top choices for Mayesville hotels

SureStay Hotel by Best Western Manning

SureStay Hotel by Best Western Manning
2.5 star property
Manning
8.6 out of 10, Excellent, (1000)
"Easy check in and out. Friendly staff, quiet and cozy. Breakfast is average but plenty to choose from. "
United States
Monica
$89 nightly
The price is $99
Jan 1 - Jan 2, 2026
Total with taxes and fees
SureStay Hotel by Best Western Manning

Hampton Inn Manning

Hampton Inn Manning
2.5 star property
Manning
8.4 out of 10, Very Good, (1001)
"Staff is always super friendly!"
United States
Kirk
$119 nightly
The price is $133
Jan 10 - Jan 11, 2026
Total with taxes and fees
Hampton Inn Manning

1912 Bed and Breakfast

1912 Bed and Breakfast
3.5 star property
Sumter
10.0 out of 10, Exceptional, (284)
"Good "
United States
Ronald
$132 nightly
The price is $132
Jan 5 - Jan 6, 2026
Total with taxes and fees
1912 Bed and Breakfast

Holiday Inn Express Sumter by IHG

Holiday Inn Express Sumter by IHG
2.5 star property
Sumter
8.8 out of 10, Excellent, (700)
"My room was spotless. The staff was friendly and the breakfast was awesome. I will definitely be staying at the Holiday Inn Express during my travels. "
United States
Kay
$98 nightly
The price is $110
Jan 25 - Jan 26, 2026
Total with taxes and fees
Holiday Inn Express Sumter by IHG

Woodspring Suites Sumter Near Shaw Afb

Woodspring Suites Sumter Near Shaw Afb
2.5 star property
Sumter
8.2 out of 10, Very Good, (141)
"The staff was very friendly and the rooms were clean. "
United States
Kevin
$104 nightly
The price is $116
Dec 26 - Dec 27
Total with taxes and fees
Woodspring Suites Sumter Near Shaw Afb

Tru by Hilton Sumter

Tru by Hilton Sumter
2.5 star property
Sumter
8.8 out of 10, Excellent, (671)
"Very clean room Will stay here in the future "
United States
michael
$85 nightly
The price is $96
Jan 4 - Jan 5, 2026
Total with taxes and fees
Tru by Hilton Sumter

Best Inn of Manning

Best Inn of Manning
2.5 star property
Manning
8.0 out of 10, Very Good, (9)
"Clean, comfortable, and efficient stay with friendly helpful staff and great value for your money."
United States
Loren
$73 nightly
The price is $81
Jan 11 - Jan 12, 2026
Total with taxes and fees
Best Inn of Manning

Hyatt Place Sumter / Downtown

Hyatt Place Sumter / Downtown
3.0 star property
Sumter
9.2 out of 10, Wonderful, (881)
"Great space good breakfast and spacious rooms clean and comfortable "
United States
Savia
$115 nightly
The price is $129
Jan 4 - Jan 5, 2026
Total with taxes and fees
Hyatt Place Sumter / Downtown

Super 8 by Wyndham Manning

Super 8 by Wyndham Manning
2.0 star property
Manning
6.4 out of 10, (374)
"Clean, nice breakfast "
United States
Tanya
$60 nightly
The price is $66
Jan 4 - Jan 5, 2026
Total with taxes and fees
Super 8 by Wyndham Manning

Spark by Hilton Sumter

Spark by Hilton Sumter
2.5 star property
Sumter
7.6 out of 10, Good, (15)
"Really enjoyed my stay. Room was clean and spacious. Jessica was very accommodating, professional and made our stay enjoyable."
United States
Cassandra
$108 nightly
The price is $121
Jan 1 - Jan 2, 2026
Total with taxes and fees
Spark by Hilton Sumter

Baymont by Wyndham Manning

Baymont by Wyndham Manning
2.5 star property
Manning
6.8 out of 10, (1000)
"Easy access to highway and plenty of parking"
United States
Jim
$80 nightly
The price is $89
Dec 28 - Dec 29
Total with taxes and fees
Baymont by Wyndham Manning

Hampton Inn Sumter

Hampton Inn Sumter
2.5 star property
Sumter
8.6 out of 10, Excellent, (489)
"Truly enjoy staying here, the staff is extremely friendly and understanding! It is very clean and comfortable! "
United States
Stefanie
$92 nightly
The price is $103
Jan 4 - Jan 5, 2026
Total with taxes and fees
Hampton Inn Sumter

Budget Inn Timmonsville

Budget Inn Timmonsville
2.0 star property
Timmonsville
7.0 out of 10, Good, (321)
"Very nice, always clean and easy on off access from route 95."
United States
Debbie
$61 nightly
The price is $68
Dec 28 - Dec 29
Total with taxes and fees
Budget Inn Timmonsville

Comfort Suites Sumter near Shaw AFB

Comfort Suites Sumter near Shaw AFB
2.5 star property
Sumter
7.2 out of 10, Good, (600)
"Very nice rooms"
United States
Seth
$100 nightly
The price is $113
Jan 1 - Jan 2, 2026
Total with taxes and fees
Comfort Suites Sumter near Shaw AFB

Americas Best Value Inn Bishopville

Americas Best Value Inn Bishopville
2.0 star property
Bishopville
7.2 out of 10, Good, (90)
"The room smelled clean, looked clean and I found no bed bugs. To look at it, we were not sure about our choice. But the wife and I were very pleased. If in the area, we will definitely stay there again. "
United States
Charles
$85 nightly
The price is $95
Dec 26 - Dec 27
Total with taxes and fees
Americas Best Value Inn Bishopville

Starlight Stays

Starlight Stays
2.5 star property
Manning
7.0 out of 10, Good, (7)
"It was nice for the area "
United States
Kendrell
$58 nightly
The price is $65
Dec 29 - Dec 30
Total with taxes and fees
Starlight Stays

Red Roof Inn Bishopville

Red Roof Inn Bishopville
2.0 star property
Bishopville
6.2 out of 10, (139)
"Clean room "
United States
Faith
$75 nightly
The price is $84
Dec 26 - Dec 27
Total with taxes and fees
Red Roof Inn Bishopville

SpringHill Suites Sumter

SpringHill Suites Sumter
2.5 star property
Sumter
9.4 out of 10, Exceptional, (452)
"Room is perfect"
United States
Sandy
$125 nightly
The price is $140
Jan 1 - Jan 2, 2026
Total with taxes and fees
SpringHill Suites Sumter

Super 8 by Wyndham Sumter

Super 8 by Wyndham Sumter
2.0 star property
Sumter
7.2 out of 10, Good, (407)
"An accessible room had no bars near the toilet and the bed was extra high. "
United States
Omer
$67 nightly
The price is $75
Jan 1 - Jan 2, 2026
Total with taxes and fees
Super 8 by Wyndham Sumter

Candlewood Suites Sumter by IHG

Candlewood Suites Sumter by IHG
2.5 star property
Sumter
8.4 out of 10, Very Good, (163)
"Everything was great"
United States
Jennifer
$134 nightly
The price is $150
Dec 26 - Dec 27
Total with taxes and fees
Candlewood Suites Sumter by IHG
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Learn more about Mayesville

Venture to Riley Field and O'Donnell House—just two of the sights around Mayesville.

Somewhere in rural South Carolina off a back road to my hometown. Saw the sunflower field and had to stop.
Photo by Caroline Nunez
Open Photo by Caroline Nunez

Top Mayesville Hotel Reviews

More cheap stays in Mayesville

Hotels in Mayesville with star-rating

Find out more about Mayesville

Top reasons to visit Mayesville

  • Charming Outdoor Spaces: Mayesville features a variety of scenic parks and botanical gardens perfect for leisurely strolls and picnics.
  • Family-Friendly Activities: Enjoy recreational areas and community events, making it ideal for family vacations.
  • Rich Local Culture: Engage with the community through Sunday school and local learning centers.
  • Romantic Getaways: The quaint atmosphere and beautiful landscapes provide a perfect setting for couples.
  • Comfortable Accommodations: A range of budget-friendly hotels and pet-friendly options cater to diverse travelers.

Find great hotels near Mayesville

Discover a variety of comfortable and budget-friendly hotel options in Mayesville, South Carolina, ranging from 2 to 3.5 stars. Whether you're seeking pet-friendly accommodations or a welcoming environment for LGBTQIA travelers, you're sure to find the perfect place to stay. Mayesville also offers a selection of homes and house information for those looking to explore longer-term options. Enjoy your visit with a stay that meets all your needs!

  • Hyatt Place Sumter / Downtown: Experience a blend of business and leisure at Hyatt Place Sumter / Downtown, located 9 miles from Mayesville. This 3-star hotel is ideal for travelers seeking a pet-friendly environment while on business trips. With amenities like a 24-hour Business Center, Conference Space, and Meeting Rooms, it caters to the needs of professionals. Enjoy the convenience of bringing your furry friends along, as pets are permitted on the premises, making your stay both productive and enjoyable.
  • Sleep Inn Sumter: Situated 11 miles from Mayesville, Sleep Inn Sumter is designed for comfort and convenience. Guests can indulge in a complimentary buffet breakfast to start the day off right. For entertainment, the hotel offers Satellite TV and Pay Movies, ensuring you stay entertained during your downtime. Its prime location near the City Center adds an extra layer of appeal, allowing guests to explore local attractions with ease.
  • Tru by Hilton Sumter: Just 11 miles from Mayesville, Tru by Hilton Sumter caters to travelers looking for a modern and pet-friendly stay. With a welcoming atmosphere, the hotel allows pets for a variable fee, making it a great choice for those traveling with dogs or cats. Guests can enjoy stylish, vibrant spaces and easy access to local attractions, making it a fantastic option for both leisure and business travelers seeking a lively and accommodating environment.

Where to stay near Mayesville

Mayesville, South Carolina, offers a charming escape for outdoor enthusiasts and families alike. Explore the friendly vibe of this small town while enjoying nearby attractions like the scenic parks and historical sites of Sumter County. Take leisurely strolls through lush landscapes or plan romantic picnics under the wide Southern skies. With its welcoming atmosphere and rich local culture, Mayesville is the perfect base for discovering the beauty and warmth of South Carolina.

  • Sumter: Located 9 miles from Mayesville, Sumter is a vibrant city known for its outdoor activities and scenic beauty. Visitors can enjoy a range of family-friendly experiences, from exploring recreational areas to shopping at local malls and centers. Notable attractions include picturesque lakes and the beautiful national parks nearby, making it a perfect destination for nature lovers. The peak travel months are March to April and July, so plan your visit during this time to enjoy the bustling atmosphere and local events.
  • Oswego: Just 5 miles from Mayesville, Oswego is a charming village that offers a quaint escape from the hustle and bustle. While the traveler arrivals remain steady throughout the year, spring and summer (March to April and July) bring a slight uptick in visitors. Oswego is perfect for those looking to unwind in a peaceful setting, with opportunities to connect with the local community and enjoy the serene landscapes that characterize this picturesque area.
  • East Sumter: Situated 7 miles away from Mayesville, East Sumter is a delightful village that attracts travelers seeking a beach experience. Although visitor numbers peak mainly from March to April and July, the area is welcoming year-round. With its close proximity to beautiful beaches, East Sumter allows for a perfect day of sunbathing and relaxation. It’s a great spot to enjoy the coastal charm while soaking up the Southern hospitality that this region is known for.

Things to do near Mayesville

Mayesville offers a charming setting for outdoor, family, and romantic vacations. Visitors can enjoy various activities, including a recreational area, boardwalk, and shopping mall center. Additionally, there are opportunities for community engagement through Sunday school and a learning center, making it a perfect destination for those looking to relax and explore local culture.

Shopping

The nearest shopping destination is Pocalla Crossing Shopping Center, located 12 miles away, offering a variety of family-friendly shops. If you're up for a drive, head to Sumter Mall, 10 miles away, or venture further to Magnolia Mall, 26 miles away, both featuring diverse shopping experiences.

Recreation

Crystal Lakes Golf Course, located 9 miles from Mayesville, offers a refreshing outdoor experience with scenic views and a challenging course. Palmetto Tennis Center, 10 miles away, provides a vibrant atmosphere for tennis enthusiasts. Dillion Park, 9 miles from town, invites relaxation with its serene walking paths and tranquil settings.

Adventure

Experience thrilling races at Florence Motor Speedway, located 20 miles from Mayesville, where adrenaline and speed collide. For family fun, visit Neptune Island Waterpark, 26 miles away, offering exciting slides and attractions. Don't miss the iconic Darlington Raceway, 27 miles from Mayesville, for heart-pounding motorsport action.

Nightlife

For a movie night, visit Regal Swamp Fox, just 25 miles from Mayesville, offering a cozy, romantic atmosphere. Alternatively, enjoy a show at Center Theatre, located 28 miles away, where you can immerse yourself in culture and entertainment with family and friends.

Booking tips and Expedia advantages for Mayesville

To save money during your visit to Mayesville, plan your trip between December and February for lower accommodation rates, with Mondays being the cheapest stay. Utilize Expedia to find eco-friendly hotels and sort options by price. Consider booking a package deal that combines flights, hotels, and activities for additional savings. Join Expedia's One Key membership for exclusive discounts and earn OneKeyCash for future stays. Look out for special sales and promotions to maximize your savings while enjoying the local attractions.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Mayesville are December to February, where the prices are slightly lower. This is in comparison to April to May and September, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Mayesville is Monday. The most expensive day to stay in Mayesville is Saturday.
  • Find cheap hotels on Expedia: Utilize Expedia’s search tool to refine your travel preferences, such as your budget, desired location, and the type of hotel you’re looking for. For instance, selecting the "Eco-certified" option will showcase sustainable and environmentally-friendly hotels that are currently available. To find the best prices and deals, simply sort the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by combining your Mayesville hotel reservation with your flights and activities through an Expedia package deal.
  • Become a One Key member: Join Expedia's One Key membership program for exclusive discounts and deals on hotel bookings. You can also earn OneKeyCash to use on future selected hotels.

Find the best attractions near Mayesville

Mayesville, South Carolina, offers a delightful mix of outdoor adventures and family-friendly activities, making it perfect for romantic getaways too. Visitors can explore local attractions such as urban parks, botanical gardens, and charming parks that provide a city experience while enjoying nature. This quaint town caters to those seeking both relaxation and exploration, ensuring a memorable vacation for travelers of all types.

  • Swan Lake Iris Gardens: Experience the tranquil beauty of this botanical garden, located 10 miles from Mayesville. With its stunning array of irises and serene walking paths, it's perfect for family outings, romantic strolls, or simply enjoying nature's artistry.
  • O'Donnell House: Immerse yourself in the rich history and culture of the region at O'Donnell House, situated 9 miles away. This historic house showcases architectural charm and offers a glimpse into local heritage, making it a must-see for history enthusiasts.
  • Sumter County Gallery of Art: Just 9 miles from Mayesville, the Sumter County Gallery of Art features diverse exhibitions that celebrate local artists and culture. The gallery provides an inspiring space to appreciate creativity and engage with the arts.

Best time to go to Mayesville

Visitor numbers in Mayesville is generally unchanged in popularity throughout the year. The best time to visit Mayesville is dependant on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are slightly high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are slightly low and weather is mostly sunny with light rain.

calendar iconCalendar Monthtemperature iconTemperaturerain iconPrecipitationmostly cloudy iconCloudinessoccupation rate iconOccupancyprice iconPricing
January45.9°F (7.7°C)Light RainMostly SunnySlightly LowSlightly Low
February49.8°F (9.9°C)Light RainMostly SunnySlightly LowSlightly Low
March55.8°F (13.2°C)Light RainMostly SunnySlightly HighAverage
April63.7°F (17.6°C)Light RainMostly SunnyAverageSlightly High
May71.4°F (21.9°C)Light RainMostly SunnyAverageSlightly High
June78.4°F (25.8°C)Light RainMostly SunnyAverageAverage
July81.3°F (27.4°C)Light RainMostly SunnySlightly HighAverage
August79.7°F (26.5°C)Light RainMostly SunnySlightly HighAverage
September75.0°F (23.9°C)Light RainMostly SunnyAverageSlightly High
October65.3°F (18.5°C)Light RainMostly SunnySlightly LowAverage
November54.9°F (12.7°C)Light RainMostly SunnyAverageAverage
December49.8°F (9.9°C)Light RainMostly SunnyAverageSlightly Low

The nearest major airports for your trip to Mayesville

To visit Mayesville, South Carolina, you can fly into two major airports. Columbia Metropolitan Airport (CAE) is located 53 miles away, with nearby hotel options like the 4-star Graduate by Hilton, 7 miles from the airport, and the Doubletree by Hilton, 6 miles away. Florence Regional Airport (FLO) is closer at 31 miles from Mayesville, offering hotel choices such as the 3.5-star TownePlace Suites by Marriott, 6 miles from the airport, and the 3-star Hotel Florence, just 2 miles away. Both airports provide convenient access to Mayesville and comfortable accommodations nearby.

Frequently asked questions

What is the best area to stay in Mayesville?
The best area to stay in Mayesville, South Carolina, is in the surrounding Sumter area, particularly near the intersection of US-378 and US-76/US-301, as Mayesville itself is a very small town with limited accommodation options.

This area of Sumter provides convenient access to Mayesville, which is just a short drive east. You'll find a selection of hotels and amenities along the main thoroughfares, making it easy to reach local points of interest. It's a practical base for exploring the region.

For solo travelers or couples looking for convenience and a relaxed stay, hotels in this Sumter corridor are ideal.
When is the best time to go to Mayesville?
For the most pleasant weather and to enjoy outdoor activities, the best times to visit Mayesville are during the spring (April to early June) and fall (late September to early November).

During these seasons, Mayesville experiences mild temperatures and lower humidity, making it ideal for exploring the area's natural beauty and historic sites. Spring brings blooming dogwoods and azaleas, while fall offers comfortable temperatures and colorful foliage.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Mayesville.
How can I save on a Mayesville hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Mayesville hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Mayesville hotel?
Prices for hotels in Mayesville often vary, but you can find a great deal from $65 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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