Mesagne Vacation Rentals from $70: Search Short-Term Rentals

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Our top choices for Mesagne vacation rentals

A dining area with a table set for four, a white vase with dried plants on a white console table, and a painting of red flowers on the wall.

1. The Ideal Shelter for Families "Discover the heart of Mesagne

Mesagne

$132 nightly

Sep 2 - Sep 3

Total with taxes and fees

A modern interior with a staircase, wooden flooring, and a small indoor garden.

2. Mezzaluna Luxury Rooms - Matrimoniale

Mesagne

$119 nightly

Sep 13 - Sep 14

Total with taxes and fees

A beach with clear turquoise water and white sand.

3. 1 Bedroom Private vacation home in Mesagne

Mesagne

$166 nightly

Aug 28 - Aug 29

Total with taxes and fees

A hotel room with a large bed, a chair, a table, and a staircase leading to another room.

4. Volta Apartment with Private Terrace, Wi-Fi and Air Conditioning

Mesagne

$232 nightly

Sep 16 - Sep 17

Total with taxes and fees

A compact kitchen with a stone arch ceiling, a dining area with white chairs, a sofa, and artwork on the walls.

5. Luxury suites in the historic center of Mesagne

Mesagne

$261 nightly

Sep 16 - Sep 17

Total with taxes and fees

A staircase with a wrought iron railing, a chandelier, and a sofa in a warmly lit interior space.

6. Apartment 'Dimora La Reggia' with Private Pool, Wi-Fi and Air Conditioning

Mesagne

$282 nightly

Sep 1 - Sep 2

Total with taxes and fees

A dining area with a table, chairs, and a bench. There is a stone archway, a window, and a shelf with items.

7. Trullo 'Pietra800' with Private Terrace, Private Garden and Air Conditioning

Mesagne

$278 nightly

Sep 14 - Sep 15

Total with taxes and fees

8. Mezzaluna Luxury Rooms - Mono Home

Mesagne

$136 nightly

Sep 13 - Sep 14

Total with taxes and fees

A modern bathroom with a freestanding bathtub, a large potted plant, and a minimalist design.

9. Mezzaluna Luxury Rooms - Suite Mono

Mesagne

$187 nightly

Sep 12 - Sep 13

Total with taxes and fees

A modern indoor pool with a water feature, arched ceilings, and a reception area visible through an archway.

10. Dimora Nettare

Brindisi Historic Center

Lawrence

$109 nightly

Sep 16 - Sep 17

Total with taxes and fees

A room with a blue and white color scheme, featuring a plant, a woven basket, and a small house model on shelves.

11. BlueBlu Apartment

Brindisi Historic Center

$115 nightly

Sep 17 - Sep 18

Total with taxes and fees

A bedroom with a bed, a mirror, a ladder, and a glass door leading to a bathroom.

12. FILIA SOLIS - Old Town SUITEs & SPA

Brindisi Historic Center

COLIN

$124 nightly

Sep 1 - Sep 2

Total with taxes and fees

A beach with clear turquoise water and a sandy shore.

13. Donnosanto Residence

Carovigno

Eyal

$124 nightly

Sep 13 - Sep 14

Total with taxes and fees

A paved pathway leading to a building with a tiled entrance.

14. Giardini Sausari Residence

Porto Cesareo

"La struttura e' molto carina anche se necessiterebbe di un rinnovo dei locali comunque le stanze sono pulite. Ogni camera ha un piccolo patio al coperto con un tavolo e 4 sedie. C'è anche un piccolo cucinino con le cose essenziali. Il frigo è capiente. La posizione è molto comoda per accedere alla spiaggia, solo 10 minuti a piedi. C'è un piccolo bar dove si può fare colazione (a costo extra). "

Paolo

$60 nightly

Sep 18 - Sep 19

Total with taxes and fees

A wall with multiple black and white photographs of cityscapes and bridges, a clock, and three vases on a wooden dresser.

15. Casa Vacanze Asariel Splendido Appartamento Vista Mare e Centro Città

Brindisi Historic Center

ALEXANDRA

$98 nightly

Aug 30 - Aug 31

Total with taxes and fees

A living room with a flat-screen TV on a wooden cabinet, a small Christmas tree, and a potted plant.

16. TOI Apartments

Brindisi Historic Center

Leonid

$100 nightly

Sep 14 - Sep 15

Total with taxes and fees

A wooden door with horizontal slats, a small window with a metal grill, and a white door with a glass panel.

17. Apartment Nuvola Rione Cappuccini

Brindisi

Randall H.

$119 nightly

Aug 24 - Aug 25

Total with taxes and fees

A bedroom with a stone ceiling, a bed, a desk, a chair, and a TV.

18. Domus ASTRA

Brindisi Historic Center

Mike

$85 nightly

Sep 4 - Sep 5

Total with taxes and fees

A hotel room with a bed, a desk, two chairs, a lamp, and framed architectural drawings on the wall.

19. The Bows and the Stars

Brindisi Historic Center

Hector P.

$197 nightly

Sep 1 - Sep 2

Total with taxes and fees

20. Villa Ghetta Country House

Leverano

Alessandro

$66 nightly

Sep 17 - Sep 18

Total with taxes and fees

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Top Mesagne Hotel Reviews

Palazzo Virgilio

10/10 Excellent

"The hotel is very close to the train station, and also to the bus stop for the airport. The staff are friendly and breakfast is good."

Arryvo

10/10 Excellent

"Excellent experience from top to bottom. Starting with the owners and extending to every member of the team—from the restaurant staff and cleaning crew to the front desk—everyone was incredibly friendly, attentive, and genuinely helpful. The hotel is very well located, and the breakfast was excellent, What really stands out is their concept of hospitality. It’s a small hotel with a big heart, where you can truly feel how much they care about their guests and want everyone to have a great experience. Highly recommended!"

Palazzo Sant'Anna Lecce

10/10 Excellent

"We travel all over the world, and this was truly one of our favorite hotels we’ve ever stayed at. The location is amazing, the rooms are beautiful, and the service is absolutely spectacular. The staff were incredibly attentive and welcoming, and every detail made our stay feel special. We loved every moment and would definitely return!"

Hotel Monte Sarago

10/10 Excellent

"Perfect hotel! (And I rarely say that) Free parking across the street is a bonus for when you’re out all day exploring or at the beach and just want to come back and relax and have dinner later. Walking distance to center of town. Exceptionally clean. Friendly and professional staff there to help you with all your needs including the reception, servers, spa attendants, and the maids. The spa was very reasonably priced and incredibly relaxing - try the “percorso” which is a little bit of everything. And last but not least the breakfast was abundant and even varied a little each day. Will return here next time I am in Puglia."

VISTA Ostuni

10/10 Excellent

"Our stay at VISTA Ostuni was nothing short of exceptional. The staff made us feel genuinely welcomed from the moment we arrived, providing warm, attentive service that was flawless throughout our stay. The property itself is absolutely stunning—beautifully designed, impeccably maintained, and every detail reflects true luxury. The panoramic views of Ostuni and the surrounding countryside are breathtaking, especially at sunset. Every meal was a delight, from the incredible breakfast to the outstanding dining experiences. The quality of the food, the atmosphere, and the service exceeded all expectations. If you're looking for a luxurious, relaxing, and unforgettable stay in Puglia, VISTA Ostuni is simply outstanding. We can't wait to return!"

Find out more about Mesagne

Everything you need to know about Mesagne vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Mesagne vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Mesagne vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Mesagne vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Mesagne. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Mesagne in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $70 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Mesagne rentals

At Expedia, we put the best Mesagne vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Mesagne rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Mesagne vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Mesagne. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

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Frequently asked questions

Can I find vacation rentals in Mesagne?

Yes, there are vacation rentals near well known attractions in Mesagne, or you can select a more secluded option if you want a relaxing place to stay. Mesagne is known for its monuments and museums. Make sure you have time to check out the restaurants while you're in the area.

What are some of the best vacation home rentals that Mesagne has to offer?

"Le Armelline", holiday home in the heart of the historic center of Lecce.: This vacation home rental outside of Mesagne is located by the ocean and offers a patio, air-conditioning, and laundry facilities to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a fridge, a stovetop, and a coffee maker, so you can cook with friends or family.

How many vacation rentals are there in Mesagne?

Choose from 5 Expedia vacation rentals in Mesagne for a memorable vacation.

What can I see and do in Mesagne?

Explore the area and family-friendly sights such as Carrisiland Resort, or get out into nature at a spot like Mesagne Dog Park. Other places in town to visit include Mesagne Castle and Piazza Orsini del Balzo.

What are vacation rentals like in Mesagne?

Vacation rentals are privately owned accommodations you can stay in for several days or longer in Mesagne. Vacation rentals offer amenities like WiFi and washers and dryers so you'll have a home away from home. If you're concerned about a sanitized environment, a vacation rental can provide a sense of privacy away from public hotel elevators and busy reception areas while still allowing you to travel. You'll also have more space in a vacation rental than in a hotel, which is another reason why a vacation rental is an attractive choice for a family getaway.

Mesagne Vacation Rentals

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Check prices for these dates

Our top choices for Mesagne vacation rentals

1. The Ideal Shelter for Families "Discover the heart of Mesagne

2. Mezzaluna Luxury Rooms - Matrimoniale

3. 1 Bedroom Private vacation home in Mesagne

4. Volta Apartment with Private Terrace, Wi-Fi and Air Conditioning

5. Luxury suites in the historic center of Mesagne

6. Apartment 'Dimora La Reggia' with Private Pool, Wi-Fi and Air Conditioning

7. Trullo 'Pietra800' with Private Terrace, Private Garden and Air Conditioning

8. Mezzaluna Luxury Rooms - Mono Home

9. Mezzaluna Luxury Rooms - Suite Mono

10. Dimora Nettare

11. BlueBlu Apartment

12. FILIA SOLIS - Old Town SUITEs & SPA

13. Donnosanto Residence

14. Giardini Sausari Residence

15. Casa Vacanze Asariel Splendido Appartamento Vista Mare e Centro Città

16. TOI Apartments

17. Apartment Nuvola Rione Cappuccini

18. Domus ASTRA

19. The Bows and the Stars

20. Villa Ghetta Country House

Find vacation rentals that suit your style

Top Mesagne Hotel Reviews

Palazzo Virgilio

Find out more about Mesagne

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