Mesagne Vacation Rentals

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Check prices for these dates

In two weeks
Nov 27 - Nov 29
In two months
Jan 8 - Jan 10
In three months
Feb 5 - Feb 7
In four months
Mar 5 - Mar 7

Our top choices for Mesagne vacation rentals

A modern interior with a staircase, wooden flooring, and a small indoor garden.

1. Mezzaluna Luxury Rooms - Matrimoniale

Mezzaluna Luxury Rooms - Matrimoniale
Mesagne
$99 nightly
The price is $99
Nov 10 - Nov 11
Total with taxes and fees
Mezzaluna Luxury Rooms - Matrimoniale
A stone archway leading to a kitchen with a microwave and wooden cabinets.

2. Private 1-bedroom vacation home in Mesagne

Private 1-bedroom vacation home in Mesagne
Mesagne
$148 nightly
The price is $148
Nov 10 - Nov 11
Total with taxes and fees
Private 1-bedroom vacation home in Mesagne
A hotel room with a large bed, a chair, a table, and a staircase leading to another room.

3. Volta Apartment with Private Terrace, Wi-Fi and Air Conditioning

Volta Apartment with Private Terrace, Wi-Fi and Air Conditioning
Mesagne
$212 nightly
The price is $212
Nov 10 - Nov 11
Total with taxes and fees
Volta Apartment with Private Terrace, Wi-Fi and Air Conditioning
A staircase with a wrought iron railing, a chandelier, and a sofa in a warmly lit interior space.

4. Apartment 'Dimora La Reggia' with Private Pool, Wi-Fi and Air Conditioning

Apartment 'Dimora La Reggia' with Private Pool, Wi-Fi and Air Conditioning
Mesagne
$196 nightly
The price is $196
Nov 10 - Nov 11
Total with taxes and fees
Apartment 'Dimora La Reggia' with Private Pool, Wi-Fi and Air Conditioning
A modern interior with a staircase, wooden flooring, and a small indoor garden.

5. Mezzaluna Luxury Rooms - Mono Home

Mezzaluna Luxury Rooms - Mono Home
Mesagne
$118 nightly
The price is $118
Nov 14 - Nov 15
Total with taxes and fees
Mezzaluna Luxury Rooms - Mono Home
A modern interior with a hanging chair, a dining area, a kitchen, and a spa area with a hot tub.

6. Mezzaluna Luxury Rooms - Suite Mono

Mezzaluna Luxury Rooms - Suite Mono
Mesagne
$199 nightly
The price is $199
Nov 10 - Nov 11
Total with taxes and fees
Mezzaluna Luxury Rooms - Suite Mono
A model lighthouse on a table with a chair and a door in the background.

7. Affittacamere AlleVolte

Affittacamere AlleVolte
Brindisi Historic Center
9.8 out of 10, Exceptional, (12 reviews)
"Fantastic stay!!"
Canada
Chiara
$67 nightly
The price is $79
Nov 28 - Nov 29
Total with taxes and fees
Affittacamere AlleVolte
A spa room with a sauna, a glass-enclosed shower, and a wooden bench.

8. Villa Neviera - Wine Resort and Spa

Villa Neviera - Wine Resort and Spa
San Donaci
7.6 out of 10, Good, (4 reviews)
"Great location - in the centre of the best wine region in the world, imo"
Norway
Markus
$70 nightly
The price is $77
Nov 11 - Nov 12
Total with taxes and fees
Villa Neviera - Wine Resort and Spa
A living room with a flat-screen TV on a wooden cabinet, a small Christmas tree, and a potted plant.

9. TOI Apartments

TOI Apartments
Brindisi Historic Center
9.0 out of 10, Wonderful, (8 reviews)
"It is a nice place and location is excellent. "
Canada
Leonid
$66 nightly
The price is $78
Nov 10 - Nov 11
Total with taxes and fees
TOI Apartments
A dining area with a wooden table and chairs, a large black and white forest-themed painting on the wall, and a colorful cushion on a brown sofa.

10. Casa Vacanze Asariel Splendido Appartamento Vista Mare e Centro Città

Casa Vacanze Asariel Splendido Appartamento Vista Mare e Centro Città
Brindisi Historic Center
9.4 out of 10, Exceptional, (15 reviews)
"The apartment is comfortable and has everything you could possibly need. Roberto the host was attentive and communicated in a timely manner everything we needed to know."
Canada
ALEXANDRA
$85 nightly
The price is $90
Nov 14 - Nov 15
Total with taxes and fees
Casa Vacanze Asariel Splendido Appartamento Vista Mare e Centro Città
A narrow street with buildings on both sides, a bell tower in the distance, and a balcony with potted plants.

11. A casa dei miei

A casa dei miei
San Pietro Vernotico
9.0 out of 10, Wonderful, (2 reviews)
"Det hele var nyt og meget rent. Værtinden var meget hjælpsom og rar"
Denmark
jan
$96 nightly
The price is $105
Dec 9 - Dec 10
Total with taxes and fees
A casa dei miei
A multi-story building with balconies and windows, surrounded by trees.

12. Dada's Cozy Appartaments

Dada's Cozy Appartaments
Carovigno
8.0 out of 10, Very good, (1 review)
$80 nightly
The price is $88
Nov 10 - Nov 11
Total with taxes and fees
Dada's Cozy Appartaments
A bedroom with a bed, a mirror, a ladder, and a glass door leading to a bathroom.

13. FILIA SOLIS - Old Town SUITEs & SPA

FILIA SOLIS - Old Town SUITEs & SPA
Brindisi Historic Center
9.6 out of 10, Exceptional, (23 reviews)
"Great apartment, close to centre and marina. Free parking close by. Had a very enjoyable time."
United Kingdom
COLIN
$119 nightly
The price is $138
Nov 10 - Nov 11
Total with taxes and fees
FILIA SOLIS - Old Town SUITEs & SPA
A hotel room with a large bed, a bedside table, a nightstand, a bathroom visible through an open door, and a small window.

14. Vie Del Salento - Primitivo with Wi-Fi and Air Conditioning

Vie Del Salento - Primitivo with Wi-Fi and Air Conditioning
San Pancrazio Salentino
$70 nightly
The price is $70
Nov 10 - Nov 11
Total with taxes and fees
Vie Del Salento - Primitivo with Wi-Fi and Air Conditioning
A modern indoor pool with a water feature, arched ceilings, and a reception area visible through an archway.

15. Dimora Nettare

Dimora Nettare
Brindisi Historic Center
9.4 out of 10, Exceptional, (82 reviews)
"Great staff and location"
United Kingdom
Lawrence
$145 nightly
The price is $166
Dec 1 - Dec 2
Total with taxes and fees
Dimora Nettare
A hotel room with a bed, a desk, two chairs, a lamp, and framed architectural drawings on the wall.

16. The Arcs and the Stars

The Arcs and the Stars
Brindisi Historic Center
10.0 out of 10, Exceptional, (12 reviews)
"Fantastic apartment. Great location. Lots ofRoom. Close to everything."
United States
Hector P.
$165 nightly
The price is $170
Dec 1 - Dec 2
Total with taxes and fees
The Arcs and the Stars
A dining area with a view of the ocean through a mural, a white balcony railing, and a door leading to another room.

17. Apartment 'Il Posto del Cuore' close to City Centre with Terrace & A/C

Apartment 'Il Posto del Cuore' close to City Centre with Terrace & A/C
Brindisi
10.0 out of 10, Exceptional, (3 reviews)
"Pros: The apartment was extremely clean and beautifully decorated. It had all amenities required and met all our expectations and beyond. The Host added lots of little touches to make it so welcoming for us and was always available if we needed to make contact. Perfect location to explore Brindisi in a quiet, safe neighbourhood. We wouldn’t hesitate to book again!"
United States
Anonymous traveler
$265 nightly
The price is $271
Nov 10 - Nov 11
Total with taxes and fees
Apartment 'Il Posto del Cuore' close to City Centre with Terrace & A/C
A modern house with a deck, outdoor seating, and a garden.

18. Il Nostro Sogno - Madonna by Tiny Away

Il Nostro Sogno - Madonna by Tiny Away
Provincia di Brindisi
$133 nightly
The price is $133
Nov 10 - Nov 11
Total with taxes and fees
Il Nostro Sogno - Madonna by Tiny Away
Pool waterfall

19. Villa Ghetta Country House

Villa Ghetta Country House
Leverano
8.4 out of 10, Very good, (10 reviews)
"Abbiamo scelto la camera quadrupla con letto a castello. Bagno grande e pulito . La sig Valentina preziosissima per spiagge , parcheggio. Sistemazione indicata per vedere lo splendido Salento e a conduzione familiare"
Italy
Stefania
$66 nightly
The price is $72
Nov 13 - Nov 14
Total with taxes and fees
Villa Ghetta Country House
A bedroom with a bed, a dresser, a mirror, and a chandelier.

20. Holiday home 'Da Gigetto Tuturano' with private garden and Wi-Fi

Holiday home 'Da Gigetto Tuturano' with private garden and Wi-Fi
Tuturano
$363 nightly
The price is $367
Nov 10 - Nov 11
Total with taxes and fees
Holiday home 'Da Gigetto Tuturano' with private garden and Wi-Fi
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Find vacation rentals that suit your style

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Top Mesagne Hotel Reviews

A bedroom with a bed, bedside table, and a tray with fruits and a drink.
Tobacco Suite

Tobacco Suite

Tobacco Suite
Mesagne

10/10 Excellent

Location was very nice, quiet area, easy to find, and very clean. Communicative tenant! I loved it
United States
Marika
Reviewed September 12, 2025
Tobacco Suite

Find out more about Mesagne

Everything you need to know about Mesagne vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Mesagne vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Mesagne vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Mesagne vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Mesagne. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Mesagne in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $76 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Mesagne rentals

At Expedia, we put the best Mesagne vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Mesagne rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Mesagne vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Mesagne. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently Asked Questions

Can I find vacation rentals in Mesagne?

Yes, there are vacation rentals near well known attractions in Mesagne, or you can select a more secluded option if you want a relaxing place to stay. Mesagne is known for its monuments and museums. Make sure you have time to check out the restaurants while you're in the area.

What are some of the best vacation home rentals that Mesagne has to offer?

Perfect oasis among Olive Trees and Private Pool, for an authentic experience!: This vacation home rental outside of Mesagne is located in a rural location and has an outdoor pool, a fireplace, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. It offers a patio, a garden, and a selection of games so you can immerse yourself in your vacation.

How many vacation rentals are there in Mesagne?

Choose from 7 Expedia vacation rentals in Mesagne for a memorable vacation.

What can I see and do in Mesagne?

Cultural attractions include Teatro Comunale di Mesagne, whereas Mesagne Dog Park is a spot to enjoy nature. Other places in town to visit include Mesagne Castle and Piazza Orsini del Balzo.

What are vacation rentals like in Mesagne?

Vacation rentals are privately owned accommodations you can stay in for several days or longer in Mesagne. Vacation rentals offer amenities like WiFi and washers and dryers so you'll have a home away from home. If you're concerned about a sanitized environment, a vacation rental can provide a sense of privacy away from public hotel elevators and busy reception areas while still allowing you to travel. You'll also have more space in a vacation rental than in a hotel, which is another reason why a vacation rental is an attractive choice for a family getaway.

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