Mesice Vacations from $869

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The Latest Mesice vacation packages

Price found within the past 48 hours. Click for updated prices.
Eurostars Thalia

Eurostars Thalia

5 out of 5
Prague City Center
Save 100% on your flight
Price was $1,346, price is now $869 per person
$869
per person
Apr 21 - Apr 27
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Prague (PRG)
8.8/10 Excellent! (709 reviews)
Extremely friendly and very gracious. It was an amazing stay and definitely worth staying if you’re wanting a very nice hotel in the centre. It took about 5/10 minutes to walk form the hotel to all the shops. Definitely recommend.

Reviewed on Feb 6, 2026

BoHo Prague Hotel, Small Luxury Hotels

BoHo Prague Hotel, Small Luxury Hotels

4 out of 5
Prague City Center
Save 100% on your flight
Price was $1,887, price is now $1,172 per person
$1,172
per person
Apr 21 - Apr 27
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Prague (PRG)
9.8/10 Exceptional! (1,004 reviews)
beautiful rooms, service and food.

Reviewed on Jan 13, 2026

Aurea Legends by Eurostars Hotel Company

Aurea Legends by Eurostars Hotel Company

4 out of 5
Prague City Center
Save 100% on your flight
Price was $1,551, price is now $964 per person
$964
per person
Apr 21 - Apr 27
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Prague (PRG)
9.8/10 Exceptional! (169 reviews)
Highly recommend this place. This is a nice hotel with friendly staff. We received a free welcome glass of champagne which was refreshing.

Reviewed on Jan 20, 2026

The Grand Mark Prague - The Leading Hotels of the World

The Grand Mark Prague - The Leading Hotels of the World

5 out of 5
Prague City Center
Save 100% on your flight
Price was $2,819, price is now $1,753 per person
$1,753
per person
Apr 21 - Apr 27
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Prague (PRG)
9.4/10 Exceptional! (731 reviews)
Amazing Hotel with a amazing Service

Reviewed on Dec 30, 2025

The Emblem Prague Hotel - Preferred Hotels & Resorts

The Emblem Prague Hotel - Preferred Hotels & Resorts

5 out of 5
Prague City Center
Save 100% on your flight
Price was $1,387, price is now $917 per person
$917
per person
Mar 18 - Mar 24
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Prague (PRG)
9.4/10 Exceptional! (1,000 reviews)
Excellent hotel. Centrally located and a hop and a skip away from the old town square

Reviewed on Jan 16, 2026

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Mesice Hotel Deals

Hilton Prague

Hilton Prague

5 out of 5
Pobrezni 311/1 Prague
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $90 total per night from Feb 22 to Feb 23
$90 total
Feb 22 - Feb 23
Total with taxes and fees
8.4/10 Very Good! (1,000 reviews)
My sister and I had an amazing time at the Hilton Prague. The staff were all extremely courteous and helpful, including the bartenders at the Cloud 9 bar. The hotel was very clean and we had no issues. I would definitely recommend this hotel to anyone traveling to Prague.

Reviewed on Jan 25, 2026

Hilton Prague
Michelangelo Grand Hotel Prague

Michelangelo Grand Hotel Prague

5 out of 5
Vladislavova 1477/20 Prague
Fully refundableReserve now, pay when you stay
$78 nightly
The price is $93 total per night from Feb 8 to Feb 9
$93 total
Feb 8 - Feb 9
Total with taxes and fees
9.4/10 Exceptional! (3,241 reviews)
Clean room, staff are all very good and accommodating

Reviewed on Feb 3, 2026

Michelangelo Grand Hotel Prague
Almanac X Alcron Prague

Almanac X Alcron Prague

5 out of 5
Stepanska 40 Prague
Fully refundableReserve now, pay when you stay
$166 nightly
The price is $191 total per night from Feb 22 to Feb 23
$191 total
Feb 22 - Feb 23
Total with taxes and fees
9.4/10 Exceptional! (856 reviews)
It was very nice! Staff and breakfast were great.

Reviewed on Jan 26, 2026

Almanac X Alcron Prague
See all 2,726 properties in Mesice
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Mesice Vacation Packages

Mesice Essential Information

Language
Czech
Currency
Czech korunas
Local Welcome
Nazdar
Local Goodbye
Ahoj
Closest Airport
Vaclav Havel Airport (PRG)
Population
1,100
Max Temp Winter
35ºF
Max Temp Summer
75ºF
Top Sights
Mělník Castle, Church of St. Wenceslas and Liblice Chateau

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Frequently asked questions

How much does a Mesice vacation package cost?
Offering great value package deals from $869 on Expedia, you'll be thrilled with how little a vacation to Mesice costs! Our packages make travel planning easier and save you more.
What are the cheapest months to go to Mesice?
If you're looking to book a cheap Mesice vacation package, consider planning a trip in November, December and January. You'll usually find better prices on airfares and hotels during these quieter months — ideal for a budget-friendly break.
How many days is enough for Mesice?
The ideal length for your Mesice vacation depends on what you'd like to see. Typically, a few days to a week will give you time to tick off all the leading attractions and discover some hidden gems along the way.
How to find the best Mesice package deals?
Bagging a cheap Mesice package deal is a breeze with Expedia. After you've entered your preferred dates and destination under our "Packages" tab, set your maximum budget, apply a couple of filters and browse what's available. You can customize your search by "Amenities," "Property type," "Guest rating" and more. Sort the results by "Price: low to high" to view the most economical Mesice package deals. Want a simple trick to get the biggest savings? Have some flexibility with your departure dates and consider traveling on a weekday, when prices are usually lower.
Is it cheaper to book a Mesice vacation as a package?
An Expedia vacation package could land you considerable savings when compared to arranging hotels and flights individually. Better still, you can personalize your Mesice escape to match your exact needs. Pick your preferred flight time, select the hotel type and add a rental car. Explore our bundles to see how much you can save.
When to book a vacation package to Mesice?
If you're planning an impromptu Mesice vacation, check out our last-minute deals that can be booked up to one week before you take off. Don't want to leave things to the last minute? You can find amazing deals on your flights and hotels by booking well in advance.
Does Expedia offer Book Now, Pay Later Mesice vacation packages?
If you're anything like us, you love jet-setting around the world but don't love the big price tag that can sometimes come with it. That's why we've created Book Now, Pay Later vacations. With help from online lender Affirm, you can break down the total cost of your Mesice vacation across 3, 6 or 12 months. There are also no late payment fees or hidden costs, so you can snap up great vacation packages with payment plans as soon as you spot them.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.