Title: The Best 5 Star Hotels in Mesice from $66 | Expedia.com

[Mesice Travel Guide](https://expedia.com/Mesice.dx6206923)[Hotels in Mesice](https://expedia.com/Mesice-Hotels.d6206923.Travel-Guide-Hotels)[Vacation Rentals in Mesice](https://expedia.com/Mesice-Vacation-Rentals.d6206923.Travel-Guide-VacationRentals)[Flights to Mesice](https://expedia.com/Cheap-Flights-To-Mesice.d6206923.Travel-Guide-Flights)[Car Rentals in Mesice](https://expedia.com/Car-Rentals-In-Mesice.d6206923.Car-Rental-Guide)[Mesice Vacation Packages](https://expedia.com/Mesice.d6206923.Destination-Travel-Guides)

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## Check availability on Mesice 5 Star Hotels

Tonight

[Mar 4 - Mar 5](https://www.expedia.com/Hotel-Search?regionId=6206923&startDate=2026-03-04&endDate=2026-03-05&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Mar 5 - Mar 6](https://www.expedia.com/Hotel-Search?regionId=6206923&startDate=2026-03-05&endDate=2026-03-06&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Mar 6 - Mar 8](https://www.expedia.com/Hotel-Search?regionId=6206923&startDate=2026-03-06&endDate=2026-03-08&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=6206923&startDate=2026-03-13&endDate=2026-03-15&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Mesice 5-star hotels

![Restaurant](https://images.trvl-media.com/lodging/1000000/120000/119600/119588/d3da02d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Almanac X Room King with Balcony | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/120000/119600/119588/0b030960.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/120000/119600/119588/96f051bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Gym](https://images.trvl-media.com/lodging/1000000/120000/119600/119588/99fdef02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

###  Almanac X Alcron Prague

[](https://www.expedia.com/Prague-Hotels-Almanac-X-Alcron-Prague.h119588.Hotel-Information)

Prague City Center

9.6/10

Exceptional

(865 reviews)

"Rooms were great as well as staff and amenities"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Andrew

$164 nightly

$189 total

Mar 15 - Mar 16

Total with taxes and fees

[](https://www.expedia.com/Prague-Hotels-Almanac-X-Alcron-Prague.h119588.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/20000/18000/17986/ac0fd08d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bars/lounges, pub, rooftop bar](https://images.trvl-media.com/lodging/1000000/20000/18000/17986/0b88324e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/20000/18000/17986/w5752h3835x5y5-d6a7ffb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 restaurants, breakfast served](https://images.trvl-media.com/lodging/1000000/20000/18000/17986/fc9b7bdf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hilton Prague Atrium

[](https://www.expedia.com/Prague-Hotels-Hilton-Prague.h17986.Hotel-Information)

Karlín

8.6/10

Excellent

(1,008 reviews)

"Great stay would definitely recommend "

![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg)

Claire

$77 nightly

$91 total

Mar 8 - Mar 9

Total with taxes and fees

[](https://www.expedia.com/Prague-Hotels-Hilton-Prague.h17986.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/8000000/7310000/7300600/7300572/2739d3de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Food and drink](https://images.trvl-media.com/lodging/8000000/7310000/7300600/7300572/2e17ed96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Spa](https://images.trvl-media.com/lodging/8000000/7310000/7300600/7300572/a6006a4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Classic Double or Twin Room with Extra Bed | Premium bedding, minibar, in-room safe, individually decorated](https://images.trvl-media.com/lodging/8000000/7310000/7300600/7300572/21953761.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Grandior Hotel Prague

[](https://www.expedia.com/Prague-Hotels-Grandior-Hotel-Prague.h7300572.Hotel-Information)

Prague City Center

9.2/10

Wonderful

(1,209 reviews)

"Friendly staff, very clean room, perfect location, amazing breakfast "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Mohamed

$73 nightly

$86 total

Mar 5 - Mar 6

Total with taxes and fees

[](https://www.expedia.com/Prague-Hotels-Grandior-Hotel-Prague.h7300572.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/3000000/2560000/2558700/2558631/772716da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/3000000/2560000/2558700/2558631/e68a8aa3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Spa](https://images.trvl-media.com/lodging/3000000/2560000/2558700/2558631/72875a5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, memory foam beds, minibar, in-room safe](https://images.trvl-media.com/lodging/3000000/2560000/2558700/2558631/19f9eb39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Michelangelo Grand Hotel Prague

[](https://www.expedia.com/Prague-Hotels-Michelangelo-Grand-Hotel-Prague.h2558631.Hotel-Information)

Prague City Center

9.4/10

Exceptional

(3,274 reviews)

"The staff were excellent, the room was perfect and the breakfast is the best ive ever had"

![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg)

Phil

$85 nightly

$101 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/Prague-Hotels-Michelangelo-Grand-Hotel-Prague.h2558631.Hotel-Information)

![Presidential Suite | Living area | 50-cm Smart TV with digital channels, TV, heated floors](https://images.trvl-media.com/lodging/72000000/71470000/71468400/71468304/d32aae85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Suite (Wintergarden) | View from room](https://images.trvl-media.com/lodging/72000000/71470000/71468400/71468304/47efaa90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, pillowtop beds, free minibar items, in-room safe](https://images.trvl-media.com/lodging/72000000/71470000/71468400/71468304/7c7856f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/72000000/71470000/71468400/71468304/24335675.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### ANDAZ PRAGUE, BY HYATT

[](https://www.expedia.com/Prague-Hotels-Andaz-Prague.h71468304.Hotel-Information)

Prague City Center

9.6/10

Exceptional

(180 reviews)

"Beautiful hotel rooms very comfortable the atmosphere was amazing very easy access to all the landmarks "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Dan

$266 nightly

$303 total

Mar 7 - Mar 8

Total with taxes and fees

[](https://www.expedia.com/Prague-Hotels-Andaz-Prague.h71468304.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/2000000/1360000/1350200/1350119/f7f774cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/2000000/1360000/1350200/1350119/0f55017a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1360000/1350200/1350119/000df504.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Junior Suite | Premium bedding, pillowtop beds, minibar, in-room safe](https://images.trvl-media.com/lodging/2000000/1360000/1350200/1350119/60b81830.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Grandium Hotel Prague

[](https://www.expedia.com/Prague-Hotels-Grandium-Hotel-Prague.h1350119.Hotel-Information)

Prague City Center

9.2/10

Wonderful

(1,071 reviews)

"Excellent staff, great room, good breakfast"

![Australia](https://a.travel-assets.com/egds/marks/flags/au.svg)

Jason

$83 nightly

$98 total

Mar 5 - Mar 6

Total with taxes and fees

[](https://www.expedia.com/Prague-Hotels-Grandium-Hotel-Prague.h1350119.Hotel-Information)

![Bar (on property)](https://images.trvl-media.com/lodging/1000000/290000/282800/282738/19e008b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Club Room, 1 King Bed | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/290000/282800/282738/45607a7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch and brunch served](https://images.trvl-media.com/lodging/1000000/290000/282800/282738/c0be7800.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/290000/282800/282738/1765ce6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Prague Marriott Hotel

[](https://www.expedia.com/Prague-Hotels-Prague-Marriott-Hotel.h282738.Hotel-Information)

Prague City Center

9.0/10

Wonderful

(1,005 reviews)

"Everything was perfect! Very quiet place close to everything you need .. walking distance to main attractions stores and restaurants! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

alan

$182 nightly

$209 total

Mar 16 - Mar 17

Total with taxes and fees

[](https://www.expedia.com/Prague-Hotels-Prague-Marriott-Hotel.h282738.Hotel-Information)

![Indoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/190000/185500/185418/21117f6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/1000000/190000/185500/185418/b32ff081.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Executive Room, Club Lounge Access, City View | Hypo-allergenic bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/190000/185500/185418/38298e8a_edited_d1a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/1000000/190000/185500/185418/ded7bd3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Grand Hotel Prague Towers

[](https://www.expedia.com/Prague-Hotels-Grand-Hotel-Prague-Towers.h185418.Hotel-Information)

Prague 4

8.4/10

Very Good

(1,002 reviews)

"Clean , Christmas decorations, helpful friendly staff "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Gemma

$86 nightly

$97 total

Mar 15 - Mar 16

Total with taxes and fees

[](https://www.expedia.com/Prague-Hotels-Grand-Hotel-Prague-Towers.h185418.Hotel-Information)

![Rooftop terrace](https://images.trvl-media.com/lodging/1000000/590000/580400/580304/94b6bf9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, Non Smoking (River) | Egyptian cotton sheets, premium bedding, down comforters, minibar](https://images.trvl-media.com/lodging/1000000/590000/580400/580304/e297d260.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/590000/580400/580304/f7642888.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Couples treatment rooms, sauna, hot tub, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/590000/580400/580304/a4c12eff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Four Seasons Hotel Prague

[](https://www.expedia.com/Prague-Hotels-Four-Seasons-Hotel-Prague.h580304.Hotel-Information)

Prague City Center

9.6/10

Exceptional

(624 reviews)

"The room was nice enough, but on the small side for the price paid and then the upgraded cost we paid on top at the hotel. The housekeeping team were excellent. The hotel had a bad sewage smell upon entry."

![Australia](https://a.travel-assets.com/egds/marks/flags/au.svg)

Merran

$685 nightly

$772 total

Mar 18 - Mar 19

Total with taxes and fees

[](https://www.expedia.com/Prague-Hotels-Four-Seasons-Hotel-Prague.h580304.Hotel-Information)

![Free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/1000000/30000/21900/21856/cf9b649d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21900/21856/32b58145.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/30000/21900/21856/4458b0df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21900/21856/9d71efbd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hilton Prague Old Town

[](https://www.expedia.com/Prague-Hotels-Hilton-Prague-Old-Town.h21856.Hotel-Information)

Prague City Center

8.8/10

Excellent

(1,002 reviews)

"Amazing hotel just close enough to the sites!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Nicole

$150 nightly

$173 total

Mar 15 - Mar 16

Total with taxes and fees

[](https://www.expedia.com/Prague-Hotels-Hilton-Prague-Old-Town.h21856.Hotel-Information)

![Interior entrance](https://images.trvl-media.com/lodging/2000000/1590000/1580800/1580712/c9b4e6be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch, dinner served; local cuisine ](https://images.trvl-media.com/lodging/2000000/1590000/1580800/1580712/e7b1048b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property - evening/night](https://images.trvl-media.com/lodging/2000000/1590000/1580800/1580712/540aa229.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch, dinner served; local cuisine ](https://images.trvl-media.com/lodging/2000000/1590000/1580800/1580712/710e87a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Art Deco Imperial Hotel

[](https://www.expedia.com/Prague-Hotels-Art-Deco-Imperial-Hotel.h1580712.Hotel-Information)

Prague City Center

9.6/10

Exceptional

(1,002 reviews)

"Wonderful hotel that is perfectly located."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Nathan

$117 nightly

$135 total

Mar 8 - Mar 9

Total with taxes and fees

[](https://www.expedia.com/Prague-Hotels-Art-Deco-Imperial-Hotel.h1580712.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/16000000/15600000/15590600/15590550/6b333a71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior entrance](https://images.trvl-media.com/lodging/16000000/15600000/15590600/15590550/f441bde9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Local cuisine](https://images.trvl-media.com/lodging/16000000/15600000/15590600/15590550/b027fde2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Local cuisine](https://images.trvl-media.com/lodging/16000000/15600000/15590600/15590550/c51468df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cosmopolitan Hotel Prague

[](https://www.expedia.com/Prague-Hotels-Cosmopolitan-Hotel-Prague.h15590550.Hotel-Information)

Prague City Center

9.6/10

Exceptional

(1,085 reviews)

"Excellent stay at this hotel. Impressed by the value, staff and condition. Very good breakfast/restaurant and ideal location. Would stay again."

![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg)

Mark

$99 nightly

$116 total

Mar 8 - Mar 9

Total with taxes and fees

[](https://www.expedia.com/Prague-Hotels-Cosmopolitan-Hotel-Prague.h15590550.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/7000000/6420000/6411400/6411386/c8a8f0f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Couples treatment rooms, massages](https://images.trvl-media.com/lodging/7000000/6420000/6411400/6411386/0eb58d85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/7000000/6420000/6411400/6411386/d77d980d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hypo-allergenic bedding, down comforters, minibar, in-room safe](https://images.trvl-media.com/lodging/7000000/6420000/6411400/6411386/a7f57bd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Emblem Prague Hotel - Preferred Hotels & Resorts

[](https://www.expedia.com/Prague-Hotels-The-Emblem-Hotel.h6411386.Hotel-Information)

Prague City Center

9.4/10

Exceptional

(1,001 reviews)

"Excellent hotel. Centrally located and a hop and a skip away from the old town square"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Angela Naneu

[](https://www.expedia.com/Prague-Hotels-The-Emblem-Hotel.h6411386.Hotel-Information)

![Front of property - evening/night](https://images.trvl-media.com/lodging/3000000/2140000/2135100/2135058/fbe66197.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hallway](https://images.trvl-media.com/lodging/3000000/2140000/2135100/2135058/a809b1c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception hall](https://images.trvl-media.com/lodging/3000000/2140000/2135100/2135058/dc6e70da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Presidential Suite, 2 Bedrooms, Terrace, City View | Living room | 32-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/3000000/2140000/2135100/2135058/65f542e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Grand Mark Prague - The Leading Hotels of the World

[](https://www.expedia.com/Prague-Hotels-The-Grand-Mark-Prague-The-Leading-Hotels-Of-The-World.h2135058.Hotel-Information)

Prague City Center

9.4/10

Exceptional

(751 reviews)

"Great value for money high end hotel buetifully decorated friendly staff at all times highly recommended "

![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg)

andrew

$258 nightly

$290 total

Mar 7 - Mar 8

Total with taxes and fees

[](https://www.expedia.com/Prague-Hotels-The-Grand-Mark-Prague-The-Leading-Hotels-Of-The-World.h2135058.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/2000000/1100000/1098400/1098376/3c94c447.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/2000000/1100000/1098400/1098376/1af02517.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1100000/1098400/1098376/aefb4f11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor banquet area](https://images.trvl-media.com/lodging/2000000/1100000/1098400/1098376/10a43bfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

###  Iron Gate Hotel & Suites Prague by BHG

[](https://www.expedia.com/Prague-Hotels-Iron-Gate-Hotel-Suites-Prague-By-BHG.h1098376.Hotel-Information)

Prague City Center

9.2/10

Wonderful

(1,001 reviews)

"Excellent staff, hotel is beautiful, great food "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Summer

$129 nightly

$149 total

Mar 22 - Mar 23

Total with taxes and fees

[](https://www.expedia.com/Prague-Hotels-Iron-Gate-Hotel-Suites-Prague-By-BHG.h1098376.Hotel-Information)

![Daily buffet breakfast (EUR 20 per person)](https://images.trvl-media.com/lodging/3000000/2810000/2807200/2807138/b1543500.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor spa tub](https://images.trvl-media.com/lodging/3000000/2810000/2807200/2807138/03124a20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/3000000/2810000/2807200/2807138/ab10bdd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/3000000/2810000/2807200/2807138/fa96f1df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Kings Court

[](https://www.expedia.com/Prague-Hotels-Hotel-Kings-Court.h2807138.Hotel-Information)

Prague City Center

9.4/10

Exceptional

(1,005 reviews)

"Room was spacious and very clean, breakfast was excellent"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Eitan

$176 nightly

$202 total

Mar 16 - Mar 17

Total with taxes and fees

[](https://www.expedia.com/Prague-Hotels-Hotel-Kings-Court.h2807138.Hotel-Information)

![Boating](https://images.trvl-media.com/lodging/2000000/1520000/1514900/1514837/13f0c7ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Presidential Suite, 1 King Bed | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/2000000/1520000/1514900/1514837/378eb9e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Couples treatment rooms, sauna, body treatments, hydrotherapy](https://images.trvl-media.com/lodging/2000000/1520000/1514900/1514837/070953fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/2000000/1520000/1514900/1514837/18c54ada.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Mandarin Oriental, Prague

[](https://www.expedia.com/Prague-Hotels-Mandarin-Oriental.h1514837.Hotel-Information)

Prague City Center

9.4/10

Exceptional

(294 reviews)

"It was really an outstanding experience "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

ricardo

$334 nightly

$379 total

Apr 1 - Apr 2

Total with taxes and fees

[](https://www.expedia.com/Prague-Hotels-Mandarin-Oriental.h1514837.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/980000/974300/974295/f04bbcc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Buffet](https://images.trvl-media.com/lodging/1000000/980000/974300/974295/a556c24b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Couples treatment rooms, steam room, body treatments, hydrotherapy](https://images.trvl-media.com/lodging/1000000/980000/974300/974295/c4e1855f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/980000/974300/974295/3b2c1620.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Kosher Hotel KING DAVID Prague

[](https://www.expedia.com/Prague-Hotels-Kosher-Hotel-KING-DAVID-Prague.h974295.Hotel-Information)

Prague City Center

8.2/10

Very Good

(937 reviews)

"it was a very pleasant stay from every angle you can look at. wonderful experience will come again!"

![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg)

Abraham

$91 nightly

$107 total

Mar 8 - Mar 9

Total with taxes and fees

[](https://www.expedia.com/Prague-Hotels-Kosher-Hotel-KING-DAVID-Prague.h974295.Hotel-Information)

![Double Room with Atrium view | Interior](https://images.trvl-media.com/lodging/2000000/1140000/1138400/1138390/9149cda2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Staircase](https://images.trvl-media.com/lodging/2000000/1140000/1138400/1138390/c42c6d38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/2000000/1140000/1138400/1138390/4459be55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/2000000/1140000/1138400/1138390/975466f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Ventana Hotel Prague

[](https://www.expedia.com/Prague-Hotels-Ventana-Hotel-Prague.h1138390.Hotel-Information)

Prague City Center

9.6/10

Exceptional

(1,001 reviews)

"Great room. Staffs are courteous "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Alexis

$143 nightly

$165 total

Mar 5 - Mar 6

Total with taxes and fees

[](https://www.expedia.com/Prague-Hotels-Ventana-Hotel-Prague.h1138390.Hotel-Information)

![Bar (on property)](https://images.trvl-media.com/lodging/1000000/980000/974600/974556/7d24d73a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/980000/974600/974556/16c471ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/980000/974600/974556/e1fcc164.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/980000/974600/974556/1887b1f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### NH Collection Prague Carlo IV

[](https://www.expedia.com/Prague-Hotels-NH-Collection-Prague-Carlo-IV.h974556.Hotel-Information)

Prague City Center

9.2/10

Wonderful

(1,004 reviews)

"Nice hotel with super friendly and helpful staff. For reasonable price the hotel also has a pool and a sauna. "

![Germany](https://a.travel-assets.com/egds/marks/flags/de.svg)

Tim

$155 nightly

$178 total

Mar 8 - Mar 9

Total with taxes and fees

[](https://www.expedia.com/Prague-Hotels-NH-Collection-Prague-Carlo-IV.h974556.Hotel-Information)

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## Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Mesice.

![Grand Majestic Hotel Prague](https://images.trvl-media.com/lodging/3000000/2870000/2861500/2861499/ccd1ae22_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Grand Majestic Hotel Prague

Truhlarska 16 Prague 

$73 nightly

$86 total

Mar 8 - Mar 9

Total with taxes and fees

9.2/10 Wonderful! (1,178 reviews)

[](https://expedia.com/Prague-Hotels-Grand-Majestic-Hotel-Prague.h2861499.Hotel-Information)

![Panorama by Verdi Hotels](https://images.trvl-media.com/lodging/1000000/530000/526100/526039/e7d59448_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Panorama by Verdi Hotels

Milevska 7 Prague 

$54 nightly

$66 total

Mar 8 - Mar 9

Total with taxes and fees

8.6/10 Excellent! (1,000 reviews)

[](https://expedia.com/Prague-Hotels-Panorama-Hotel-Prague.h526039.Hotel-Information)

![Courtyard by Marriott Prague Airport](https://images.trvl-media.com/lodging/2000000/1630000/1627500/1627470/9b15537d_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Courtyard by Marriott Prague Airport

Aviaticka 1092/8 Prague 

$168 nightly

$193 total

Mar 28 - Mar 29

Total with taxes and fees

9.2/10 Wonderful! (1,001 reviews)

[](https://expedia.com/Prague-Hotels-Courtyard-By-Marriott-Prague-Airport.h1627470.Hotel-Information)

Still don't see what you're looking for?

[See all properties in Mesice.](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F5%2F2026&endDate=3%2F6%2F2026&regionId=6206923&star=50)

You can also use these popular filters to refine your search.

[Pool](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F5%2F2026&endDate=3%2F6%2F2026&regionId=6206923&star=50&star=50&amenities=POOL)[Spa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F5%2F2026&endDate=3%2F6%2F2026&regionId=6206923&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F5%2F2026&endDate=3%2F6%2F2026&regionId=6206923&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F5%2F2026&endDate=3%2F6%2F2026&regionId=6206923&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F5%2F2026&endDate=3%2F6%2F2026&regionId=6206923&star=50&star=50&amenities=WATER_PARK)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

## Top Mesice Hotel Reviews

![Michelangelo Grand Hotel Prague](https://images.trvl-media.com/lodging/3000000/2560000/2558700/2558631/97701066_y.jpg)

### Michelangelo Grand Hotel Prague

10/10 Excellent

"Clean room and great location "

[](https://expedia.com/Prague-Hotels-Michelangelo-Grand-Hotel-Prague.h2558631.Hotel-Information)

![Grandium Hotel Prague](https://images.trvl-media.com/lodging/2000000/1360000/1350200/1350119/ad23ebdc_y.jpg)

### Grandium Hotel Prague

10/10 Excellent

"The location was perfect. Great pub across the street, train a few blocks away, they have car service too. "

[](https://expedia.com/Prague-Hotels-Grandium-Hotel-Prague.h1350119.Hotel-Information)

![Hilton Prague](https://images.trvl-media.com/lodging/1000000/20000/18000/17986/de5e9df3_y.jpg)

### Hilton Prague

10/10 Excellent

"Spacious room. Clean comfortable bed. Nice pool and Thai massage "

[](https://expedia.com/Prague-Hotels-Hilton-Prague.h17986.Hotel-Information)

![Cosmopolitan Hotel Prague](https://images.trvl-media.com/lodging/16000000/15600000/15590600/15590550/c51468df_y.jpg)

### Cosmopolitan Hotel Prague

10/10 Excellent

"Friendly staff; excellent breakfast; excellent location"

[](https://expedia.com/Prague-Hotels-Cosmopolitan-Hotel-Prague.h15590550.Hotel-Information)

![Art Deco Imperial Hotel](https://images.trvl-media.com/lodging/2000000/1590000/1580800/1580712/686cb114_y.jpg)

### Art Deco Imperial Hotel

10/10 Excellent

"Spacious room with comfortable bed. Toiletries were good quality and complimentary wine and coffee was appreciated. There were tea bags but no kettle which was confusing but otherwise room facilities were excellent. The hotel is beautiful particularly the restaurant. Breakfast was generous and a very good range of food and drink was on offer. Good location to access all the sites, with a convenient tram stop close by. Highly recommend this hotel. "

[](https://expedia.com/Prague-Hotels-Art-Deco-Imperial-Hotel.h1580712.Hotel-Information)

![ Iron Gate Hotel & Suites Prague by BHG](https://images.trvl-media.com/lodging/2000000/1100000/1098400/1098376/1837ab47_y.jpg)

###  Iron Gate Hotel & Suites Prague by BHG

10/10 Excellent

"The staff was wonderful. Polite and helpful. The room was beautiful. The location was perfect. "

[](https://expedia.com/Prague-Hotels-Iron-Gate-Hotel-Suites-Prague-By-BHG.h1098376.Hotel-Information)

![Grandior Hotel Prague](https://images.trvl-media.com/lodging/8000000/7310000/7300600/7300572/2739d3de_y.jpg)

### Grandior Hotel Prague

10/10 Excellent

"Hotel very clean"

[](https://expedia.com/Prague-Hotels-Grandior-Hotel-Prague.h7300572.Hotel-Information)

![ Almanac X Alcron Prague](https://images.trvl-media.com/lodging/1000000/120000/119600/119588/96f051bf_y.jpg)

###  Almanac X Alcron Prague

10/10 Excellent

"Everything was superb, from the minute we walked in. Everyone had a smile for us."

[](https://expedia.com/Prague-Hotels-Almanac-X-Alcron-Prague.h119588.Hotel-Information)

## Find out more about Mesice

You enjoy the finer things in life, both at home and on vacation. Add further pleasure on your next trip to Mesice by treating yourself to the best of the best when it comes to accommodation. It's an ideal fusion. There's no reason to delay a getaway to Mesice any longer. You'll join the multitudes of vacationers who have made Mesice so fashionable in the last year. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Don't wait any longer. Reserve one of our 5-star hotels in Mesice and indulge in the finer things in life for a while.

### Book the Best Mesice 5-Star Hotels

You'll have a wonderful time at one of these 5-star hotels. Excellent customer care, spacious rooms, and deeply relaxing spa offerings are waiting for you. You're sure to find exactly the accommodation you need. You'll also enjoy a high standard of care and meticulous guest relations, so get ready to kick back and indulge. What kind of amenities will make your stay a wonderful one? A concierge to help you suggest the next attraction to visit? A rejuvenating facial treatment to help your cares fall away? Comfortable beds, lip-smacking main courses, and even a hot tub in the bathroom...these hotels will leave you amazed. Want to see for yourself? Explore our listings and pick the perfect accommodation for your needs. 

But you aren't going to spend your entire vacation in your room, of course. We hear you. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what you end up doing, the 5-star hotels in Mesice are waiting for you to rest up after a busy day.

### Make Your Escape

The results are in, and Mesice 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. It's time to plan your next great escape -- Expedia can help you land a great deal on accommodation. Select one of our Mesice 5-star hotels today and dive into in total tranquility at your convenience.

## Frequently asked questions

### What are the best 5-star hotels in Mesice?

### How much does it cost to stay in a 5-star hotel in Mesice?

> - Search for the lowest price per night from $66

### What makes a hotel 5 stars in Mesice?