Misiones Province Vacations & Trips from $419

Book a Hotel + Flight or Car together to unlock savings

Photo by EMITUR/Argentina Travel
  • Plan, book, travel with confidence

  • Better together

    Save up to $2,000 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Your Misiones Province Vacation

See and do more with a Misiones Province vacation package. Whether you're going for its fishing, walking trails, watersports, or something else, our package deals make travel planning a breeze. Your trip to Misiones Province wouldn't be complete without exploring its best cities, starting with Posadas, Puerto Libertad and Puerto Rico. Whether you're traveling for a couple of days or a couple of weeks, Expedia are here to help you tailor-make your next Misiones Province vacation.

Top destinations in Misiones Province

A large waterfall with multiple tiers, surrounded by lush greenery and a viewing platform with people observing.

Puerto Iguazú

Puerto Iguazú
A natural rock arch formation in turquoise waters with a mountainous backdrop.

Posadas

Posadas
A large waterfall with a boat in the middle of the river.

Puerto Libertad

Puerto Libertad
Ancient brick ruins with columns and intricate carvings.

San Ignacio

San Ignacio

The Latest Misiones Province Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Falls Iguazú Hotel & Spa

Falls Iguazú Hotel & Spa

Save 100% on your flight
$419
per person
Oct 30 - Nov 2
found 1 day ago
Roundtrip flight included
Buenos Aires (BUE) to Iguazu (IGR)
9.2/10 Wonderful! (484 reviews)
The hotel is a standard type with beautiful grounds and pool. The rooms are clean and roomy with all the traditional comforts of contemporary hotel. The stay includes breakfast and dinner but the dinner service is basic. The staff is very professional and helpful- they assisted us with our last minute requests.

Reviewed on Jul 18, 2026

Gran Melia Iguazú

Gran Melia Iguazú

$825
per person
Sep 9 - Sep 13
found 1 day ago
Roundtrip flight included
Buenos Aires (AEP) to Iguazu (IGR)
9.4/10 Exceptional! (1,004 reviews)
Love this place. Pool can use more heating

Reviewed on Aug 7, 2026

Reserva Natural Iguazú - Pristine Luxury Camp

Reserva Natural Iguazú - Pristine Luxury Camp

Save 100% on your flight
$663
per person
Nov 2 - Nov 5
found 23 hours ago
Roundtrip flight included
Buenos Aires (AEP) to Iguazu (IGR)
9.4/10 Exceptional! (6 reviews)
Selvaje lodge Iguazu

Selvaje lodge Iguazu

Save 100% on your flight
$558
per person
Nov 2 - Nov 5
found 23 hours ago
Roundtrip flight included
Buenos Aires (AEP) to Iguazu (IGR)
9.2/10 Wonderful! (395 reviews)
Loi Suites Iguazú Hotel

Loi Suites Iguazú Hotel

Save 100% on your flight
$716
per person
Nov 2 - Nov 5
found 23 hours ago
Roundtrip flight included
Buenos Aires (AEP) to Iguazu (IGR)
9.2/10 Wonderful! (1,000 reviews)
A beautiful, clean hotel with a great restaurant and helpful staff in a relaxing and lovely setting. I hope to be able to return some day.

Reviewed on Jun 11, 2026

Where to stay in Misiones Province

Find the best Misiones Province areas and neighborhoods for the activities you enjoy most.Learn more about Misiones Province
Learn more about Misiones Province

Downtown Iguazú

The abundant dining options and secluded waterfalls are top of the list for many visitors to Downtown Iguazú. A stop by Plaza San Martin or Café Central Casino might round out your trip.

Zona Granja

Zona Granja is noteworthy for its waterfalls, and you can make a stop at top attractions like Biocentro Iguazu and La Aripuca.

Comandante Andresito

If you're looking for some top things to see and do in Comandante Andresito and surrounding area, you can visit Port and Hummingbird Garden.

Santa Maria de Iguazú

While Santa Maria de Iguazú might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Port and Hummingbird Garden.

Villa Tacuara

While there might not be top attractions in Villa Tacuara, you can explore the larger area and discover places like Hummingbird Garden and Iguazu Casino.

Best Places to Vacation in Misiones Province

1. Enjoy Puerto Iguazú with a travel package

Puerto Iguazú in Misiones Province, Argentina offers a unique and diverse outdoor vacation experience. With its stunning waterfalls, lush jungles, and scenic hiking trails, nature lovers will be in paradise. The area is also perfect for romantic getaways and wildlife enthusiasts, with opportunities for hunting and observing exotic animals. Adventure seekers can enjoy thrilling tours and activities, while those looking for a more relaxed experience can explore the rainforest at their own pace. Additionally, Puerto Iguazú offers shopping tours and sightseeing opportunities, ensuring there is something for everyone in this vibrant destination.

  • Travelers tend to stay 3 days in Puerto Iguazú

2. Create memories in Posadas with a vacation package

Posadas, located in the Misiones Province of Argentina, offers a unique outdoor vacation experience. With its stunning natural beauty, visitors can indulge in activities such as spa treatments, waterskiing, exploring ancient ruins, and enjoying the picturesque river views. The city is also known for its trendy atmosphere and delicious seafood, which can be savored while boating on the river or sipping coffee at local cafes. For those seeking spiritual solace, Posadas boasts beautiful churches. Additionally, swimming in the refreshing waters of the region is a popular pastime. Whether you're exploring the outdoors or immersing yourself in local culture, Posadas has something for everyone.

  • The peak season is from December to February
  • The off-peak season is from March to May
  • Travelers tend to stay 2 days in Posadas

3. Find your perfect Puerto Libertad vacation

Puerto Libertad in Misiones Province, Argentina, offers an exceptional outdoor vacation experience. With its family-friendly atmosphere, it is perfect for a getaway with your loved ones. The lush jungles and rainforests surrounding the area provide a stunning backdrop for exploration and adventure. You can immerse yourself in the beauty of nature, discover breathtaking waterfalls, and indulge in delicious dining experiences. Puerto Libertad truly offers something for everyone, whether you seek a romantic retreat or an exciting family vacation.

  • The peak season is from February to April
  • The off-peak season is from August to October
  • Travelers tend to stay 2 days in Puerto Libertad

4. Experience Obera with a travel package

Obera, located in the Misiones Province of Argentina, offers a fantastic atmosphere for a family vacation. With its natural parks, theme parks, spas, and adventurous activities, there's something for everyone to enjoy. Explore the beautiful landscapes and immerse yourself in the local culture. Take a cruise or an ocean cruise to experience the region's waterways and marine life. Obera is a perfect destination for families seeking both relaxation and excitement. Whether you're exploring the natural wonders or enjoying thrilling activities, Obera promises a memorable vacation experience for the whole family.

  • The peak season is from July to September
  • The off-peak season is from March to May
  • Travelers tend to stay 1 day in Obera

6. Book your ideal Comandante Andresito with a vacation package

San Ignacio, located in the Misiones Province of Argentina, offers a unique cultural vacation experience. With its picturesque landscapes and friendly people, the town is perfect for exploring gardens, swimming, and visiting historical monuments. Immerse yourself in the local atmosphere by participating in destination activities, tours, and sightseeing. Don't miss the opportunity to visit the aquarium and zoo, which offer a chance to see diverse wildlife. Whether you're looking for a relaxing getaway or an adventure-filled vacation, San Ignacio has something for everyone.

  • The peak season is from July to September
  • The off-peak season is from April to June

5. Escape to San Ignacio with a vacation package

Dos de Mayo, located in Misiones Province, Argentina, offers an incredible outdoor vacation experience. Immerse yourself in the lush greenery of the surrounding rainforests, where you can explore nature trails, spot exotic wildlife, and marvel at breathtaking waterfalls. The warm and welcoming local atmosphere invites you to discover the rich culture and traditions of the region. Enjoy outdoor activities such as hiking, birdwatching, and fishing, or simply unwind and soak in the natural beauty. Dos de Mayo provides a serene and rejuvenating escape, perfect for those seeking an unforgettable outdoor adventure.

  • The peak season is from December to February
  • The off-peak season is from April to June
  • Travelers tend to stay 1 day in San Ignacio

Find the Best Misiones Province Vacation Packages

Misiones Province Essential Information

Language
Spanish
Currency
Argentine pesos
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Cataratas del Iguazu Intl. Airport (IGR)
Top Sights
Iguazu National Park, Hummingbird Garden and Jardin de los Picaflores

Misiones Province Hotel Deals

Gran Melia Iguazú

Gran Melia Iguazú

Parque Nacional Iguazu Puerto Iguazú Misiones
Fully refundableReserve now, pay when you stay
$475 nightly
$484 total
Sep 2 - Sep 3
9.4/10 Exceptional! (1,007 reviews)
"Love this place. Pool can use more heating"

Reviewed on Aug 7, 2026

Gran Melia Iguazú
Hotel Saint George

Hotel Saint George

Avenida Cordoba 148 Puerto Iguazú Misiones
Fully refundableReserve now, pay when you stay
$113 nightly
$120 total
Aug 9 - Aug 10
Hotel Saint George
Loi Suites Iguazú Hotel

Loi Suites Iguazú Hotel

Selva Iriapu Sin Numero Puerto Iguazú Misiones
Fully refundableReserve now, pay when you stay
$381 nightly
$390 total
Aug 17 - Aug 18
9.2/10 Wonderful! (1,000 reviews)
"A beautiful, clean hotel with a great restaurant and helpful staff in a relaxing and lovely setting. I hope to be able to return some day."

Reviewed on Jun 11, 2026

Loi Suites Iguazú Hotel
See all 395 properties in Misiones Province
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Misiones Province vacation package cost?
Starting from as low as $419, a vacation package is your portal to low-priced travel. Create your own Misiones Province getaway by picking from our great range of flights, hotels and rental cars.
How do I get a cheap travel package to Misiones Province?
Think of all the wonderful things you could do in Misiones Province with extra cash in your wallet. Watch your savings stack up when you bundle your airfare and hotel bookings into a Misiones Province vacation package. You have plenty of choice with Expedia too. In fact, you can take your pick of over 550 air carriers and 1,000,000 properties across the globe. Whether you're taking a vacation with the whole family or embarking on a solo adventure, organizing a trip to Misiones Province is better with a package.
Where should I stay in Misiones Province?
Puerto Iguazú is a highly recommended vacation spot. Book a nice hotel and experience everything this city has to offer, such as Iguazu Falls.
What are the top hotels in Misiones Province?
For properties in Puerto Iguazú with comfy beds and friendly service, look up Gran Melia Iguazú and Iguazú Jungle Lodge. If you're visiting Posadas as well, you can look forward to a great night's sleep at Continental Posadas Hotel or Bagu Grand Crucero Posadas.
How far in advance should I book my Misiones Province vacation?
It can be tricky to know exactly when the best time is to book your Misiones Province trip. But typically the earlier you book, the lower the prices. Sometimes, you can reserve your flights and hotels nearly 12 months before your departure date. If you're considering a last-minute getaway, no need to stress! There are fabulous deals advertised on Expedia every single day.
What does an Expedia Misiones Province travel package include?
Flights, hotels and rental cars — you'll find them all here. With Expedia, you can shape your Misiones Province package just how you like it. All you have to do is work out what you need. Once you've made your booking, you can add on fun things like experiences and activities. The more you bundle, the bigger the savings!
What should I know before booking a Misiones Province travel package?
When you book your hotels, flights and car rentals together, you'll be rewarded with incredible discounts. Whether you're organizing an island getaway in a villa or would rather stay in a comfortable hotel in the city, Expedia can make it happen for less.
Can I choose my airline with a Misiones Province Expedia vacation package?
Expedia offers access to more than 550 airline partners worldwide, so you certainly can. Just select your preferred air carrier and create your ideal Misiones Province getaway.
Does Expedia offer Book Now, Pay Later Misiones Province vacation packages?
With one of our vacation packages, you can customize both your getaway and a payment plan. Expedia can help reduce financial burden relating to your journey with a Book Now, Pay Later booking, thanks to us joining forces with online lender Affirm. That way, all you have to worry about is preparing to take to the skies.
If I'm not able to travel, can I cancel my Misiones Province vacation package?
Certainly, and we'll help you every step of the way. You may be able to cancel or change your Misiones Province vacation package at no cost within 24 hours of booking. But you may be charged a fee by your airline, hotel or car rental company if you booked more than 24 hours ago. If your circumstances unexpectedly change, take a look at our Customer Service Portal for further information.

Stay near popular Misiones Province attractions

A river flanked by lush green hills, a bridge, and a house on a hill.

Triple Frontier

8.8/10 (248 reviews)
Find out about the history of Puerto Iguazú with a stop at Triple Frontier. Discover the area's beautiful waterfalls, or seek out its local tours.
See properties
A river with a waterfall surrounded by dense green forest and a cloudy sky.

Port

8.4/10 (28 reviews)
Explore the waterfront of Port and enjoy other activities such as hiking in Puerto Iguazú. Discover the area's beautiful waterfalls, or seek out its local tours.
See properties
A hummingbird perched on a colorful bird feeder with red, blue, and yellow flowers.

Hummingbird Garden

8.2/10 (66 reviews)
Explore the lovely green spaces of Hummingbird Garden and also enjoy the hiking trails in Puerto Iguazú. Discover the area's beautiful waterfalls, or seek out its local tours.
See properties
Ancient brick ruins with columns and intricate carvings.
Photo by Mark Rentz

San Ignacio Miní

8.2/10 (13 reviews)
Find out about the history of San Ignacio when you spend time at San Ignacio Miní. Amble around the area's gardens or visit its monuments.
See properties

Duty Free Shop Puerto Iguazu

7.8/10 (100 reviews)
You can search for that perfect souvenir at Duty Free Shop Puerto Iguazu during your stay in Puerto Iguazú. Discover the beautiful waterfalls in this romantic area, or enjoy its local tours.
See properties

Argentina-Paraguay Bridge

7.0/10 (41 reviews)
You can learn about the history of Posadas when you stop by Argentina-Paraguay Bridge. Stroll along the riverfront or visit the spas while you're in the area.
See properties

Iguazu Casino

7.8/10 (83 reviews)
Why not try your luck with a visit to Iguazu Casino during your visit to Puerto Iguazú? Amble around the area's scenic parks or seek out the local tours.
See properties

Parque Republica del Paraguay

9.2/10 (12 reviews)
Explore the great outdoors at Parque Republica del Paraguay, a lovely green space in Posadas. Stroll along the riverfront or visit the spas while you're in the area.
See properties

What to do in Misiones Province

Iguazu Falls: 2-Day Argentinian and Brazilian Iguazu Falls

Iguazu Falls: 2-Day Argentinian and Brazilian Iguazu Falls

$49
per adult
Iguazu Falls: 2-Day Argentinian and Brazilian Iguazu Falls
Private Tour 1-2 Day Tour: Both sides of the Iguazu Falls

Private excursion to both sides of the Iguaçu Falls

$127
per adult
Private excursion to both sides of the Iguaçu Falls
Sightseeing Bus Tour of Foz do Iguaçu

Sightseeing Bus Tour of Foz do Iguaçu

$29
per adult
Sightseeing Bus Tour of Foz do Iguaçu
See all activities in Misiones Province
Explore a world of travel with Expedia

Other vacations you might like

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.