Missouri Artists on Main Tours

Plan a trip to see Missouri Artists on Main

Price found within the past 48 hours. Click for updated prices.
The Principal Hotel

The Principal Hotel

3.5 out of 5
Price was $608, price is now $429 per person
$429
per person
Oct 30 - Nov 3
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to St. Louis (STL)
9.8/10 Exceptional! (120 reviews)
Very clean place to stay. We would definitely come back.

Reviewed on Aug 30, 2025

The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
Price was $702, price is now $468 per person
$468
per person
Oct 4 - Oct 6
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to St. Louis (STL)
9.2/10 Wonderful! (1,562 reviews)
Very quiet, nice area. Walkable to restaurants and shops. The staff was extremely welcoming. This is a beautiful facility and is even pet friendly. I would highly recommend this hotel if you need to stay in this area.

Reviewed on Aug 29, 2025

White House at Grand Central

White House at Grand Central

4 out of 5
Grand Center
Price was $642, price is now $477 per person
$477
per person
Oct 30 - Nov 3
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to St. Louis (STL)
8.6/10 Excellent! (116 reviews)
It was very clean and nicely decorated. The house is a cool old building. The AC worked great (important, as it was super muggy outside.) I was only there for a couple nights but I think it would have worked well for a longer stay.

Reviewed on Jul 9, 2025

Popular places to visit

"The first St. Charles Borromeo Church, like this one, was constructed of vertical, hewn logs placed directly in the ground: an architectural style unique to the French in the New World during the 17th and 18th centuries. The church has been rebuilt on its original location. Jesse Francis, a local preservationist with 20 years experience restoring 18th French log buildings, directed the reconstruction. The work was done completely by with period tools in the manner of the 18th century. The church is part of an on-going historical interpretive program based on a re-creation of daily activities in this old French village."

Historic Main Street

You can learn about the history of St. Charles with a trip to Historic Main Street. Check out the shops and top-notch restaurants in this family-friendly area.

Historic Main Street
Lewis & Clark festival

Frontier Park

You can find out about the history of St. Charles with a visit to Frontier Park. Check out the shops and top-notch restaurants in this family-friendly area.

Frontier Park

First Missouri State Capitol Historic Site

You can learn about the history of St. Charles when you stop by First Missouri State Capitol Historic Site. Discover the top-notch restaurants and great live music in this family-friendly area.

First Missouri State Capitol Historic Site

SSM Health St. Joseph Hospital

Though SSM Health St. Joseph Hospital might be what brings you to town, perhaps you'll have a chance to explore more of St. Charles while you are here.

SSM Health St. Joseph Hospital

Lewis & Clark Boathouse and Nature Center

You can spend time exploring the galleries in Lewis & Clark Boathouse and Nature Center during your travels in St. Charles. Experience the great live music and acclaimed theater scene in this family-friendly area.

Lewis & Clark Boathouse and Nature Center

Ameristar Casino St. Charles

Why not try your luck with a visit to Ameristar Casino St. Charles during your time in St. Charles? Experience the great live music and acclaimed theater scene in this family-friendly area.

Ameristar Casino St. Charles

Best Lodging Options Near Missouri Artists on Main

Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive, Maryland Heights, MO
Hollywood Casino & Hotel St. Louis
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
1 Ameristar Blvd, St. Charles, MO
Ameristar Casino Resort and Spa
Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

2.5 out of 5
1190 S Main St, St. Charles, MO
Country Inn & Suites by Radisson, St. Charles Historic District
The St. Charles Guest House, lovely historic home, fun for families and groups

The St. Charles Guest House, lovely historic home, fun for families and groups

St. Charles
The St. Charles Guest House, lovely historic home, fun for families and groups
1830's Luxury Brick Cottage, Cozy Fireplace, right off the Cobblestone Streets!

1830's Luxury Brick Cottage, Cozy Fireplace, right off the Cobblestone Streets!

St. Charles
1830's Luxury Brick Cottage, Cozy Fireplace, right off the Cobblestone Streets!
Best Western Plus The Charles Hotel

Best Western Plus The Charles Hotel

3 out of 5
1425 South 5th Street, St. Charles, MO
Best Western Plus The Charles Hotel
1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.

1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.

St. Charles
1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.
Luxurious couples retreat just steps from Historic Main Street in St. Charles!

Luxurious couples retreat just steps from Historic Main Street in St. Charles!

Saint Charles
Luxurious couples retreat just steps from Historic Main Street in St. Charles!
Scenic South Main Apartment with Breathtaking Views for 3 Guests

Scenic South Main Apartment with Breathtaking Views for 3 Guests

Saint Charles
Scenic South Main Apartment with Breathtaking Views for 3 Guests
See all 451 properties in Missouri Artists on Main
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.