This seagoing vessel is often on the itineraries of travelers to St. Charles Historic District. But Lewis & Clark Boathouse and Nature Center isn't the only drawcard here. Ameristar Casino St. Charles, Hollywood Casino Amphitheatre, and Historic Main Street are some other recommended attractions nearby.
Lewis & Clark Boathouse and Nature Center Tours
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Price found within the past 48 hours. Click for updated prices.
Hilton Garden Inn Chesterfield
Save 100% on your flight
Price was $396, price is now $279 per person
$279
per person
Oct 2 - Oct 5
found 10 hours ago
Roundtrip flight included
Denver (DEN) to St. Louis (STL)
8.2/10 Very Good! (763 reviews)
I booked online and paid via the app. When I arrived on site they explained they had overbooked and had no rooms available. The staff was amazing and went above and beyond and secured a room at another location. Thank you to the staff for taking care of us.
Reviewed on Jul 26, 2025
The Wildwood Hotel
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Price was $768, price is now $407 per person
$407
per person
Oct 2 - Oct 5
found 10 hours ago
Roundtrip flight included
Denver (DEN) to St. Louis (STL)
9.2/10 Wonderful! (1,562 reviews)
Always comfortable, always convenient and reliable when I'm visiting the area. It's my go-to hotel in the area.
Reviewed on Aug 25, 2025
The Cheshire
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Price was $527, price is now $381 per person
$381
per person
Oct 22 - Oct 25
found 18 hours ago
Roundtrip flight included
Dallas (DFW) to St. Louis (STL)
8.6/10 Excellent! (1,006 reviews)
The Cheshire kept well from of old! We felt back in to the ages yet very 21C amenities. The location is perfect to explore St. Louis. We'd like to come back!
Reviewed on Aug 23, 2025
Popular places to visit
Frontier Park
You can find out about the history of St. Charles with a visit to Frontier Park. Check out the shops and top-notch restaurants in this family-friendly area.
Historic Main Street
4/5(34 reviews)
You can learn about the history of St. Charles with a trip to Historic Main Street. Check out the shops and top-notch restaurants in this family-friendly area.
Ameristar Casino St. Charles
4/5(240 reviews)
Why not try your luck with a visit to Ameristar Casino St. Charles during your time in St. Charles? Experience the great live music and acclaimed theater scene in this family-friendly area.
Missouri Artists on Main
You can spend an afternoon browsing the exhibits at Missouri Artists on Main in St. Charles. Check out the shops and top-notch restaurants in this family-friendly area.
First Missouri State Capitol Historic Site
4/5(2 reviews)
You can learn about the history of St. Charles when you stop by First Missouri State Capitol Historic Site. Discover the top-notch restaurants and great live music in this family-friendly area.
SSM Health St. Joseph Hospital
Though SSM Health St. Joseph Hospital might be what brings you to town, perhaps you'll have a chance to explore more of St. Charles while you are here.
Best Lodging Options Near Lewis & Clark Boathouse and Nature Center
Check availability on hotels close to Lewis & Clark Boathouse and Nature Center
Hollywood Casino & Hotel St. Louis
777 Casino Center Drive, Maryland Heights, MO
Ameristar Casino Resort and Spa
1 Ameristar Blvd, St. Charles, MO
Best Western Plus The Charles Hotel
1425 South 5th Street, St. Charles, MO
Country Inn & Suites by Radisson, St. Charles Historic District
1190 S Main St, St. Charles, MO
Comfort Suites St Charles - St Louis
1400 S 5th St, St. Charles, MO
Drury Plaza Hotel St. Louis St. Charles
380 Mulholland Drive, St. Charles, MO
Hampton Inn & Suites St. Charles Old Town Area
1410 SOUTH 5TH STREET, St. Charles, MO
Historic headquarters of city founder! Gated parking!
Saint Charles
Charming Duplex on Main
Saint Charles
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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