Picayune Vacations from $448

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Your Picayune Vacation

Enjoy unforgettable adventures when you lock in a vacation package to Picayune. Whether you're a history buff, foodie or just a traveler who loves discovering new places, there's something for everyone in this exciting city. Crosby Aboretum and Millbrook Country Club are among the must-see sights to check out during your trip to Picayune. A couple of clicks is all it takes to build a tailored Picayune vacation on Expedia.

The Latest Picayune vacation packages

Price found within the past 48 hours. Click for updated prices.
Comfort Inn & Suites Crystal Inn Sportsplex

Comfort Inn & Suites Crystal Inn Sportsplex

2.5 out of 5
Price was $537, price is now $448 per person
$448
per person
Mar 2 - Mar 7
found 4 hours ago
Roundtrip flight included
Boston (BOS) to Gulfport (GPT)
6.2/10 (222 reviews)
I loved how big and roomy my room was. Very well kept place. Comfortable room. Great breakfast. This will be my go to place to stop on my Florida to Texas trips. Chastity was great checking me in and getting me signed up for the choice program with discounts on every stay. Thank you Comfort Inn. Well done.

Reviewed on Jan 17, 2026

Holiday Inn Express Gulfport Beach by IHG

Holiday Inn Express Gulfport Beach by IHG

3 out of 5
Price was $889, price is now $692 per person
$692
per person
Apr 1 - Apr 6
found 1 day ago
Roundtrip non-stop flight included
Milwaukee (MKE) to Gulfport (GPT)
9.4/10 Exceptional! (772 reviews)
Wish the pool was heated for colder months, but not a deal breaker for next nee years eve

Reviewed on Jan 7, 2026

Hotel Whiskey in Pass Christian

Hotel Whiskey in Pass Christian

3.5 out of 5
Price was $630, price is now $524 per person
$524
per person
Mar 2 - Mar 7
found 4 hours ago
Roundtrip flight included
Boston (BOS) to Gulfport (GPT)
9.4/10 Exceptional! (600 reviews)
Great stay! Easy check and check out

Reviewed on Jan 7, 2026

Gulf Hills Hotel & Resort

Gulf Hills Hotel & Resort

2.5 out of 5
Price was $803, price is now $673 per person
$673
per person
Mar 26 - Mar 30
found 20 hours ago
Roundtrip non-stop flight included
Minneapolis (MSP) to Gulfport (GPT)
8.8/10 Excellent! (775 reviews)
Property was very clean, staff were very helpful and pleasant. Room was clean, air conditioner and heat were working well. Have stayed here before and will be back.

Reviewed on Jan 3, 2026

Hollywood Casino Gulf Coast

Hollywood Casino Gulf Coast

3.5 out of 5
Price was $790, price is now $669 per person
$669
per person
Apr 1 - Apr 6
found 1 day ago
Roundtrip non-stop flight included
Milwaukee (MKE) to Gulfport (GPT)
8/10 Very Good! (1,001 reviews)
Loved tve jacuzzi tub

Reviewed on Jan 15, 2026

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Discover the most popular places to visit in Picayune

Millbrook Country Club

Enjoy a round of golf in Picayune at Millbrook Country Club. Wander the riverfront in this family-friendly area.

Millbrook Country Club

Picayune Hotel Deals

Holiday Inn Express Picayune-Stennis Space Center by IHG

Holiday Inn Express Picayune-Stennis Space Center by IHG

2.5 out of 5
1001 Dauphin Street Picayune MS
Fully refundable
$103 nightly
The price is $112 total per night from Feb 1 to Feb 2
$112 total
Feb 1 - Feb 2
Total with taxes and fees
8.8/10 Excellent! (645 reviews)
Clean room and facility.

Reviewed on Dec 5, 2025

Holiday Inn Express Picayune-Stennis Space Center by IHG
Days Inn by Wyndham Picayune

Days Inn by Wyndham Picayune

2 out of 5
450 S Lofton Avenue Picayune MS
Fully refundableReserve now, pay when you stay
$59 nightly
The price is $64 total per night from Jan 25 to Jan 26
$64 total
Jan 25 - Jan 26
Total with taxes and fees
6/10 (360 reviews)
Personal was friendly.

Reviewed on Jan 3, 2026

Days Inn by Wyndham Picayune
Heritage Inn Picayune

Heritage Inn Picayune

2 out of 5
1122 Memorial Blvd. Picayune MS
$79 nightly
The price is $86 total per night from Jan 21 to Jan 22
$86 total
Jan 21 - Jan 22
Total with taxes and fees
8.2/10 Very Good! (287 reviews)
Clean room and the nice staff

Reviewed on Jan 4, 2026

Heritage Inn Picayune
See all 1,027 properties in Picayune
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Picayune Vacation Packages

Picayune Essential Information

Language
English
Currency
U.S dollars
Population
10,700
Max Temp Winter
65ºF
Max Temp Summer
90ºF
Top Sights
Crosby Aboretum and Millbrook Country Club

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Frequently asked questions

How much does a Picayune vacation package cost?
Offering great value package deals from $448 on Expedia, you'll be surprised at how little a vacation to Picayune costs! Our packages make travel planning easier and save you more.
What are the cheapest months to go to Picayune?
If you're looking to score a cheap Picayune vacation package, consider planning a trip in July, September and October. You're likely to find better rates on flights and hotels during these months — perfect for a budget-friendly break.
How many days is enough for Picayune?
Usually, a handful of days is enough to visit the major sights during your Picayune vacation. But if you want to have time to unwind or go on day trips, consider extending your itinerary.
How to find the best Picayune package deals?
Landing a cheap Picayune package deal is a cinch with Expedia. Once you've entered your destination and preferred dates under our "Packages" tab, set your budget range, add a few filters and see what's available. You can tailor your search by "Amenities," "Property type," "Popular locations" and more. Sort the results by "Price: low to high" to discover the most wallet-friendly Picayune package deals. Want a simple trick to score even more savings? Have some flexibility with your departure dates and consider traveling on a weekday, when prices are often lower.
Is it cheaper to book a Picayune vacation as a package?
You can enjoy significant savings on your next Picayune getaway by booking a customized vacation package. Click on the "Package" heading, then enter your destination and travel dates to see the best hotel prices and airfares. Bundling can save travelers hundreds of dollars. Consider adding a rental car and you may score a better deal.
When to book a vacation package to Picayune?
If you've got your Picayune vacation dates confirmed, book early to snap up some terrific deals. With Expedia, you can generally reserve some flights up to a year in advance. Prefer spur-of-the-moment adventures? Our last-minute deals are perfect for quick escapes.
Does Expedia offer Book Now, Pay Later Picayune vacation packages?
Jet off on your dream trip to Picayune with help from Expedia's Book Now, Pay Later vacations. No need to scrimp and save or wait until your next paycheck — we've partnered with online lender Affirm to give you financial flexibility. Our vacation packages with payment plans mean you can split the cost across 3, 6 or 12 months. With no late payment fees or hidden charges, it's easy to budget for your trip and snap up bargains before they sell out.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.