Picayune Vacations from $614

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Your Picayune Vacation

Enjoy unforgettable adventures when you lock in a vacation package to Picayune. Whether you're a history buff, foodie or just a traveler who loves discovering new places, there's something for everyone in this exciting city. Crosby Aboretum and Millbrook Country Club are among the must-see sights to check out during your trip to Picayune. A couple of clicks is all it takes to build a tailored Picayune vacation on Expedia.

The Latest Picayune vacation packages

Price found within the past 48 hours. Click for updated prices.
Red Roof Inn Gulfport - Biloxi Airport

Red Roof Inn Gulfport - Biloxi Airport

2 out of 5
Price was $671, price is now $614 per person
$614
per person
Jun 24 - Jun 28
found 1 day ago
Roundtrip flight included
Charlotte (CLT) to Gulfport (GPT)
5.8/10 (1,004 reviews)
Rooms was cleaned, southern hospitality, everything was on point

Reviewed on May 21, 2026

The Pass Picture Book

The Pass Picture Book

2.5 out of 5
Price was $916, price is now $753 per person
$753
per person
Jul 1 - Jul 4
found 1 day ago
Roundtrip non-stop flight included
Pittsburgh (PIT) to Gulfport (GPT)
No reviews
The Markham Hotel

The Markham Hotel

3 out of 5
Price was $757, price is now $679 per person
$679
per person
Aug 4 - Aug 7
found 1 day ago
Roundtrip non-stop flight included
Pittsburgh (PIT) to Gulfport (GPT)
10/10 Exceptional! (14 reviews)
Fabulous hotel and the staff was wonderful!! Clean, updated and the roof top has great views. I forgot something at the hotel and they called me immediately advising they found it. Highly recommend this hotel and staff.

Reviewed on May 20, 2026

Centennial Plaza Resort Gulfport

Centennial Plaza Resort Gulfport

2.5 out of 5
Price was $708, price is now $639 per person
$639
per person
Aug 4 - Aug 7
found 1 day ago
Roundtrip non-stop flight included
Pittsburgh (PIT) to Gulfport (GPT)
9/10 Wonderful! (1,009 reviews)
We love this hotel! Our family has come the last 4 Spring Breaks. Great staff. Great location. The new beignets are amazing - our family still talks about how great they were to have at the end of each day. Looking forward to visiting again next year.

Reviewed on May 18, 2026

Handsboro Pointe Condo & Suites

Handsboro Pointe Condo & Suites

4 out of 5
Price was $783, price is now $715 per person
$715
per person
Aug 4 - Aug 7
found 1 day ago
Roundtrip non-stop flight included
Pittsburgh (PIT) to Gulfport (GPT)
9.8/10 Exceptional! (87 reviews)
This property is clean and well maintained! We were in town combining some business with pleasure. The location was perfect for us!

Reviewed on May 14, 2026

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Discover the most popular places to visit in Picayune

Millbrook Country Club

Enjoy a round of golf in Picayune at Millbrook Country Club. Wander the riverfront in this family-friendly area.

Millbrook Country Club

Picayune Hotel Deals

Holiday Inn Express Picayune-Stennis Space Center by IHG

Holiday Inn Express Picayune-Stennis Space Center by IHG

2.5 out of 5
1001 Dauphin Street Picayune MS
Fully refundable
$122 nightly
The price is $133 total per night from Jun 7 to Jun 8
$133 total
Jun 7 - Jun 8
Total with taxes and fees
8.8/10 Excellent! (685 reviews)
"Close to family"

Reviewed on May 13, 2026

Holiday Inn Express Picayune-Stennis Space Center by IHG
Heritage Inn Picayune

Heritage Inn Picayune

2 out of 5
1122 Memorial Blvd. Picayune MS
$82 nightly
The price is $90 total per night from May 24 to May 25
$90 total
May 24 - May 25
Total with taxes and fees
8.2/10 Very Good! (302 reviews)
"The hotel was dated but clean and quiet and reasonably priced. A good selection of fast food restaurants and Walmart nearby. Staff was always courteous and helpful. The only issue we weren't happy with was the bed. It was very, very hard and we both were in pain during the nights and stiff and sore ..."

Reviewed on May 20, 2026

Heritage Inn Picayune
Hollywood Casino Gulf Coast

Hollywood Casino Gulf Coast

3.5 out of 5
711 Hollywood Blvd Bay St Louis MS
$120 nightly
The price is $131 total per night from Jun 15 to Jun 16
$131 total
Jun 15 - Jun 16
Total with taxes and fees
8/10 Very Good! (1,002 reviews)
"Amazing staff and clean smelling rooms"

Reviewed on May 20, 2026

Hollywood Casino Gulf Coast
See all 1,070 properties in Picayune
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Picayune Vacation Packages

Picayune Essential Information

Language
English
Currency
U.S dollars
Population
10,700
Max Temp Winter
65ºF
Max Temp Summer
90ºF
Top Sights
Crosby Aboretum and Millbrook Country Club

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Frequently asked questions

How much does a Picayune vacation package cost?
Offering great value package deals from $614 on Expedia, you'll be surprised at how little a vacation to Picayune costs! Our packages make travel planning easier and save you more.
What are the cheapest months to go to Picayune?
If you're looking to score a cheap Picayune vacation package, consider planning a trip in July, September and October. You're likely to find better rates on flights and hotels during these months — perfect for a budget-friendly break.
How many days is enough for Picayune?
Usually, a handful of days is enough to visit the major sights during your Picayune vacation. But if you want to have time to unwind or go on day trips, consider extending your itinerary.
How to find the best Picayune package deals?
Landing a cheap Picayune package deal is a cinch with Expedia. Once you've entered your destination and preferred dates under our "Packages" tab, set your budget range, add a few filters and see what's available. You can tailor your search by "Amenities," "Property type," "Popular locations" and more. Sort the results by "Price: low to high" to discover the most wallet-friendly Picayune package deals. Want a simple trick to score even more savings? Have some flexibility with your departure dates and consider traveling on a weekday, when prices are often lower.
Is it cheaper to book a Picayune vacation as a package?
You can enjoy significant savings on your next Picayune getaway by booking a customized vacation package. Click on the "Package" heading, then enter your destination and travel dates to see the best hotel prices and airfares. Bundling can save travelers hundreds of dollars. Consider adding a rental car and you may score a better deal.
When to book a vacation package to Picayune?
If you've got your Picayune vacation dates confirmed, book early to snap up some terrific deals. With Expedia, you can generally reserve some flights up to a year in advance. Prefer spur-of-the-moment adventures? Our last-minute deals are perfect for quick escapes.
Does Expedia offer Book Now, Pay Later Picayune vacation packages?
Jet off on your dream trip to Picayune with help from Expedia's Book Now, Pay Later vacations. No need to scrimp and save or wait until your next paycheck — we've partnered with online lender Affirm to give you financial flexibility. Our vacation packages with payment plans mean you can split the cost across 3, 6 or 12 months. With no late payment fees or hidden charges, it's easy to budget for your trip and snap up bargains before they sell out.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.