Picayune Vacations from $344

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Your Picayune Vacation

Enjoy unforgettable adventures when you lock in a vacation package to Picayune. Whether you're a history buff, foodie or just a traveler who loves discovering new places, there's something for everyone in this exciting city. Crosby Aboretum and Millbrook Country Club are among the must-see sights to check out during your trip to Picayune. A couple of clicks is all it takes to build a tailored Picayune vacation on Expedia.

The Latest Picayune vacation packages

Price found within the past 48 hours. Click for updated prices.
Gulf Hills Hotel & Resort

Gulf Hills Hotel & Resort

2.5 out of 5
Price was $460, price is now $344 per person
$344
per person
Jun 4 - Jun 8
found 21 hours ago
Roundtrip non-stop flight included
Atlanta (ATL) to Gulfport (GPT)
9/10 Wonderful! (794 reviews)
Cool and eclectic place close to everything, downtown OS and Biloxi. Hotel is older but renovated and pretty well done. On a golf course if you golf. No restaurant onsite but golf club has an Italian place with limited hours. Clean and a good value. Check out The Lady May restaurant about 5 miles away… it’s amazing and super reasonable.

Reviewed on Mar 6, 2026

Holiday Inn Express Gulfport Beach by IHG

Holiday Inn Express Gulfport Beach by IHG

3 out of 5
Price was $608, price is now $424 per person
$424
per person
Jun 4 - Jun 8
found 21 hours ago
Roundtrip non-stop flight included
Atlanta (ATL) to Gulfport (GPT)
9.4/10 Exceptional! (816 reviews)
The hotel was very clean and nicely updated. The elevators are a bit slow though.

Reviewed on Mar 13, 2026

Hotel Whiskey in Pass Christian

Hotel Whiskey in Pass Christian

3.5 out of 5
Price was $569, price is now $432 per person
$432
per person
Jun 4 - Jun 8
found 21 hours ago
Roundtrip non-stop flight included
Atlanta (ATL) to Gulfport (GPT)
9.4/10 Exceptional! (629 reviews)
Slept well, very close to the beach. Beautiful area.

Reviewed on Mar 15, 2026

Hollywood Casino Gulf Coast

Hollywood Casino Gulf Coast

3.5 out of 5
Price was $1,045, price is now $798 per person
$798
per person
Jun 4 - Jun 8
found 21 hours ago
Roundtrip non-stop flight included
Atlanta (ATL) to Gulfport (GPT)
8/10 Very Good! (1,001 reviews)
Room was a smoke room did not like the smoke odor

Reviewed on Feb 24, 2026

Holiday Inn Gulfport Airport by IHG

Holiday Inn Gulfport Airport by IHG

3 out of 5
Price was $504, price is now $394 per person
$394
per person
Jun 4 - Jun 8
found 21 hours ago
Roundtrip non-stop flight included
Atlanta (ATL) to Gulfport (GPT)
8.8/10 Excellent! (1,003 reviews)
Upon arrival, the hotel and room were clean. Good, helpful staff assisted with check-in and checkout. I did use and appreciate the pantry in the lobby. Overall worth the price and I had a great stay!

Reviewed on Feb 8, 2026

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Discover the most popular places to visit in Picayune

Millbrook Country Club

Enjoy a round of golf in Picayune at Millbrook Country Club. Wander the riverfront in this family-friendly area.

Millbrook Country Club

Picayune Hotel Deals

Holiday Inn Express Picayune-Stennis Space Center by IHG

Holiday Inn Express Picayune-Stennis Space Center by IHG

2.5 out of 5
1001 Dauphin Street Picayune MS
Fully refundable
$132 nightly
The price is $144 total per night from Mar 22 to Mar 23
$144 total
Mar 22 - Mar 23
Total with taxes and fees
9/10 Wonderful! (665 reviews)
Not there for business. Room could have been swept better … old chicken nugget on floor by bed. Parking was tight.

Reviewed on Mar 14, 2026

Holiday Inn Express Picayune-Stennis Space Center by IHG
Heritage Inn Picayune

Heritage Inn Picayune

2 out of 5
1122 Memorial Blvd. Picayune MS
$85 nightly
The price is $93 total per night from Mar 26 to Mar 27
$93 total
Mar 26 - Mar 27
Total with taxes and fees
8.2/10 Very Good! (292 reviews)
All good

Reviewed on Mar 1, 2026

Heritage Inn Picayune
Days Inn by Wyndham Picayune

Days Inn by Wyndham Picayune

2 out of 5
450 S Lofton Avenue Picayune MS
Fully refundableReserve now, pay when you stay
$51 nightly
The price is $56 total per night from Mar 22 to Mar 23
$56 total
Mar 22 - Mar 23
Total with taxes and fees
6.2/10 (365 reviews)
Time for new towels, mine were like sand paper, the room is in need of some TLC. The toilet paper holder fell out of the wall.

Reviewed on Feb 28, 2026

Days Inn by Wyndham Picayune
See all 1,048 properties in Picayune
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Picayune Vacation Packages

Picayune Essential Information

Language
English
Currency
U.S dollars
Population
10,700
Max Temp Winter
65ºF
Max Temp Summer
90ºF
Top Sights
Crosby Aboretum and Millbrook Country Club

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Frequently asked questions

How much does a Picayune vacation package cost?
Offering great value package deals from $344 on Expedia, you'll be surprised at how little a vacation to Picayune costs! Our packages make travel planning easier and save you more.
What are the cheapest months to go to Picayune?
If you're looking to score a cheap Picayune vacation package, consider planning a trip in July, September and October. You're likely to find better rates on flights and hotels during these months — perfect for a budget-friendly break.
How many days is enough for Picayune?
Usually, a handful of days is enough to visit the major sights during your Picayune vacation. But if you want to have time to unwind or go on day trips, consider extending your itinerary.
How to find the best Picayune package deals?
Landing a cheap Picayune package deal is a cinch with Expedia. Once you've entered your destination and preferred dates under our "Packages" tab, set your budget range, add a few filters and see what's available. You can tailor your search by "Amenities," "Property type," "Popular locations" and more. Sort the results by "Price: low to high" to discover the most wallet-friendly Picayune package deals. Want a simple trick to score even more savings? Have some flexibility with your departure dates and consider traveling on a weekday, when prices are often lower.
Is it cheaper to book a Picayune vacation as a package?
You can enjoy significant savings on your next Picayune getaway by booking a customized vacation package. Click on the "Package" heading, then enter your destination and travel dates to see the best hotel prices and airfares. Bundling can save travelers hundreds of dollars. Consider adding a rental car and you may score a better deal.
When to book a vacation package to Picayune?
If you've got your Picayune vacation dates confirmed, book early to snap up some terrific deals. With Expedia, you can generally reserve some flights up to a year in advance. Prefer spur-of-the-moment adventures? Our last-minute deals are perfect for quick escapes.
Does Expedia offer Book Now, Pay Later Picayune vacation packages?
Jet off on your dream trip to Picayune with help from Expedia's Book Now, Pay Later vacations. No need to scrimp and save or wait until your next paycheck — we've partnered with online lender Affirm to give you financial flexibility. Our vacation packages with payment plans mean you can split the cost across 3, 6 or 12 months. With no late payment fees or hidden charges, it's easy to budget for your trip and snap up bargains before they sell out.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.