
Picayune Vacations from $330
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to $2,000 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Your Picayune Vacation
Enjoy unforgettable adventures when you lock in a vacation package to Picayune. Whether you're a history buff, foodie or just a traveler who loves discovering new places, there's something for everyone in this exciting city. Crosby Aboretum and Millbrook Country Club are among the must-see sights to check out during your trip to Picayune. A couple of clicks is all it takes to build a tailored Picayune vacation on Expedia.
The Latest Picayune vacation packages
Price found within the past 48 hours. Click for updated prices.

Hotel Whiskey in Pass Christian
Price was $384, price is now $330 per person
$330
per person
Aug 17 - Aug 20
found 1 day ago
Roundtrip flight included
Tampa (TPA) to Gulfport (GPT)
9.4/10 Exceptional! (652 reviews)
So beautiful the amenities were good. The only place that I really have is that the mattresses will way too far for what we pay for the room. He would think with a nice room like that you want people to sleep well.
Reviewed on May 21, 2026

Porter Condos
Price was $581, price is now $460 per person
$460
per person
Aug 17 - Aug 20
found 1 day ago
Roundtrip flight included
Tampa (TPA) to Gulfport (GPT)
10/10 Exceptional! (8 reviews)
Very nice apartment with a quiet atmosphere. It was very clean and newly furnished. It was a very good price, cheaper than other stays in the same area. Very close to downtown Ocean Springs for good food, shopping, and nightlife.
Reviewed on May 3, 2026


Country Inn & Suites by Radisson, Biloxi-Ocean Springs, MS
Price was $907, price is now $729 per person
$729
per person
Jun 25 - Jul 2
found 7 hours ago
Roundtrip non-stop flight included
Pittsburgh (PIT) to Gulfport (GPT)
6.6/10 (1,012 reviews)
The hot tub was nice, but the controls and faucet head was loose. The mirror surrounding the tub was cloudy and streaked. The ottoman was very worn. The shower valve was stuck, so no shower. The bed was okay and the room was reasonably clean.
Reviewed on May 17, 2026

Gil's Bayou Cabins
Price was $475, price is now $388 per person
$388
per person
Aug 17 - Aug 20
found 1 day ago
Roundtrip flight included
Tampa (TPA) to Gulfport (GPT)
9.8/10 Exceptional! (7 reviews)
peaceful but right around the corner from activity. could walk out of pier. very nice private cabin. you can pull right up to the door.
Reviewed on May 15, 2026
Discover the most popular places to visit in Picayune
Millbrook Country Club
Enjoy a round of golf in Picayune at Millbrook Country Club. Wander the riverfront in this family-friendly area.
Picayune Hotel Deals

Holiday Inn Express Picayune-Stennis Space Center by IHG
1001 Dauphin Street Picayune MS
Fully refundable
$122 nightly
The price is $133 total per night from Jun 21 to Jun 22
$133 total
Jun 21 - Jun 22
Total with taxes and fees
8.8/10 Excellent! (685 reviews)
"Close to family"
Reviewed on May 13, 2026

Heritage Inn Picayune
1122 Memorial Blvd. Picayune MS
$82 nightly
The price is $90 total per night from May 24 to May 25
$90 total
May 24 - May 25
Total with taxes and fees
8.2/10 Very Good! (302 reviews)
"The hotel was dated but clean and quiet and reasonably priced. A good selection of fast food restaurants and Walmart nearby. Staff was always courteous and helpful. The only issue we weren't happy with was the bed. It was very, very hard and we both were in pain during the nights and stiff and sore ..."
Reviewed on May 20, 2026

Hollywood Casino Gulf Coast
711 Hollywood Blvd Bay St Louis MS
$120 nightly
The price is $131 total per night from Jun 15 to Jun 16
$131 total
Jun 15 - Jun 16
Total with taxes and fees
8/10 Very Good! (1,002 reviews)
"Amazing staff and clean smelling rooms"
Reviewed on May 20, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Picayune Vacation Packages
Picayune Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Population | 10,700 |
Max Temp Winter | 65ºF |
Max Temp Summer | 90ºF |
Top Sights | Crosby Aboretum and Millbrook Country Club |
More vacations you might like
Frequently asked questions
Explore a world of travel with Expedia
- Vacation Homes in Picayune Station
- Hotels near Picayune Station
- Hotels near Millbrook Country Club
- Carriere Hotels
- Hotels near NASA Stennis Space Center
- Hotels near Infinity Science Center
- Hotels near Hancock County Welcome Center
- Hotels near Hancock County Sports Complex
- Kiln Hotels
- Cottages in Kiln
- Motels in Kiln
- B&B in Kiln
- Rv Parks in Kiln
- Cabin Rentals in Kiln
- Condo Rentals in Kiln
- Guest Houses in Kiln
- Hotels near Lazy Magnolia Brewing Company
- Pearlington Hotels
- B&B in Pearlington
- Resorts in Pearlington
- Apartments in Pearlington
- Condo Rentals in Pearlington
- Diamondhead Hotels
- Condo Rentals in Diamondhead
- Cheap Hotels in Diamondhead
- Hotels with an Indoor Pool in Diamondhead
- Rv Parks in Diamondhead
- Cabin Rentals in Diamondhead
- Casino Hotels in Diamondhead
- Golf Hotels in Diamondhead
- 5 Star Hotels in Diamondhead
- Pet-Friendly Hotels in Diamondhead
- Beach Hotels in Diamondhead
- Apartments in Diamondhead
- Resorts in Diamondhead
- Hotels with Restaurants in Diamondhead
- Hotels with Hot Tubs in Diamondhead
- 4 Star Hotels in Diamondhead
- B&B in Diamondhead
- Hotel Wedding Venues Hotels in Diamondhead
- Historic Hotels in Diamondhead
- Motels in Diamondhead
- Cottages in Diamondhead
- Hotels with Connecting Rooms in Diamondhead
- Hotels with Bars in Diamondhead
- Resorts & Hotels with Spas in Diamondhead
- Luxury Hotels in Diamondhead
- Hotels with a Pool in Diamondhead
- Guest Houses in Diamondhead
- Aparthotels in Diamondhead
- Family Hotels in Diamondhead
- 3 Star Hotels in Diamondhead
- Hotels near Diamondhead Country Club
- Shoreline Park Hotels
- Poplarville Hotels
- Cabin Rentals in Poplarville
- Motels in Poplarville
- Luxury Hotels in Poplarville
- Cottages in Poplarville
- Millbrook Country Club
- Nasa Stennis Space Center
- Infinity Science Center
- Hancock County Sports Complex
- Kiln Vacations
- Visit Kiln
- Lazy Magnolia Brewing Company
- Pearlington Vacations
- Visit Pearlington
- Diamondhead Vacations
- Diamondhead Country Club
- Visit Diamondhead
- Poplarville Vacations
- Hollywood Casino
- Bridges Golf Club
- Visit Poplarville
- Car rentals near Nicholson
- Car rentals near Carriere
- Car rentals near NASA Stennis Space Center
- Car rentals near Hancock County Welcome Center
- Car rentals near Kiln
- Hertz Rental Cars in Kiln
- Car rentals near White Sand
- Car rentals near Pearlington
- Car rentals near Diamondhead
- Budget Rental Cars in Diamondhead
- Car rentals near Diamondhead Country Club
- Car rentals near Shoreline Park
- Car rentals near Poplarville
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.



















