Grand Isle, FL
Port St. Joe
Visit Grand Isle
Grand Isle Hotel Deals
Comfort Suites
264 N Tyndall Pkwy Panama City FL
$95 nightly
The price is $102 total per night from Sep 2 to Sep 3
$102 total
Sep 2 - Sep 3
Total with taxes and fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (801 reviews)
"Jessica the front desk person was amazing and the only reason a gave a ranking to the staff. Everyone else acted like i was a bother and when I asked for something like water to be replaced in the gym the staff gave me an excuse for the whole 3 days I was there. Can it be cleaned better yes like ..."
Reviewed on Aug 9, 2026
Holiday Inn Express Hotel & Suites Panama City-Tyndall by IHG
5627 E Highway 22 State Route Panama City FL
$102 nightly
The price is $109 total per night from Aug 27 to Aug 28
$109 total
Aug 27 - Aug 28
Total with taxes and fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (513 reviews)
"Staff was great! Couldn’t figure out the television and someone came up to help me even after explaining on the phone. Great service & went the extra mile!"
Reviewed on Aug 9, 2026
Days Inn by Wyndham Panama City/Callaway
435 North Tyndall Parkway Panama City FL
$58 nightly
The price is $62 total per night from Aug 12 to Aug 13
$62 total
Aug 12 - Aug 13
Total with taxes and fees
Stay at this hotel in Panama City. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. Popular attractions ...
Driftwood Inn
2105 U.S. 98 Mexico Beach FL
$227 nightly
The price is $254 total per night from Aug 11 to Aug 12
$254 total
Aug 11 - Aug 12
Total with taxes and fees
Book a stay at this beach hotel in Port St. Joe. Enjoy free WiFi, free parking, and a beach locale. Popular attractions Mexico Beach and Mexico Beach Park are ...
9.6/10 Exceptional! (97 reviews)
"This was a great find on Mexico beach! Beautiful hotel! Would stay again. I was terrified when we arrived late after a 6 hour drive, I didn’t see the sign to call because our code wasn’t working. I opened a hallway door and went down to the lobby and was able to easily get ahold of someone and get ..."
Reviewed on Aug 8, 2026
MainStay Suites Port Saint Joe South
3951 E Highway 98 Port St. Joe FL
$138 nightly
The price is $154 total per night from Aug 27 to Aug 28
$154 total
Aug 27 - Aug 28
Total with taxes and fees
Book a stay at this business-friendly hotel in Port St. Joe. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
The Port Inn - Port St Joe, an Ascend Collection Hotel
501 Monument Ave. Port St. Joe FL
Fully refundable
$179 nightly
The price is $201 total per night from Sep 8 to Sep 9
$201 total
Sep 8 - Sep 9
Total with taxes and fees
Stay at this hotel in Port St. Joe. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
9/10 Wonderful! (466 reviews)
"It was a pleasant and relaxing trip! The staff were helpful and friendly. Very knowledgeable about the inn and surrounding areas. Would recommend to stay on ground floor. Had stairs no elevator but it's very short two flights. Fresh coffee and good breakfast."
Reviewed on Jul 31, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Grand Isle
Find the best Grand Isle areas and neighborhoods for the activities you enjoy most.
Photo by Matt Russell
Open Photo by Matt Russell
Downtown Port St. Joe
While visiting Downtown Port St. Joe, you might make a stop by sights like Port Saint Joe City Hall and Port St. Joe Marina.
Cape Breezes
While Cape Breezes isn't home to many top sights, T.H. Stone Memorial St. Joseph Peninsula State Park and St. Joseph Peninsula State Park are some notable places to visit nearby.
Gulf Aire
While Gulf Aire isn't home to many top sights, Saint Joe Beach and Mexico Beach are some notable places to visit nearby.
Waterside Village
Though Waterside Village might not have many top sights, you can venture to the surrounding area to see attractions like Mexico Beach Marina and Mexico Beach.
Palms
While there might not be top attractions in Palms, you can explore the larger area and discover places like Mexico Beach and Mexico Beach Marina.
