Title: Visit Santa Ana: 2026 Santa Ana, Antigua Guatemala Travel Guide | Expedia.com [Hotels in Santa Ana](https://expedia.com/Santa-Ana-Antigua-Guatemala-Hotels.0-n553248635975847775-0.Travel-Guide-Filter-Hotels)[Flights to Antigua Guatemala](https://expedia.com/Cheap-Flights-To-Antigua-Guatemala.d180589.Travel-Guide-Flights)[Things to do in Antigua Guatemala](https://expedia.com/Things-To-Do-In-Antigua-Guatemala.d180589.Travel-Guide-Activities)[Car Rentals in Santa Ana](https://expedia.com/Car-Rentals-In-Santa-Ana.d553248635975847775.Car-Rental-Guide)[Santa Ana Vacations](https://expedia.com/Santa-Ana.d553248635975847775.Destination-Travel-Guides) # Santa Ana ## Antigua Guatemala ![Iglesia de Nuestra Señora de Santa Ana, aldea Santa Ana en Antigua Guatemala.](https://images.trvl-media.com/place/553248635975847775/dbfc8e66-dcda-4ff9-9ea4-b39c7cec35ab.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Santa Ana Things to do Hotels Where to stay [Antigua Guatemala Travel Guide](https://expedia.com/Antigua-Guatemala.dx180589) --- ### Popular places to visit ![Panoramic inside the ruins of Antigua's Cathedral, one of the many buildings that collapsed after the earthquake that destroyed the city in 1773.](https://images.trvl-media.com/place/180589/1dda07b1-9d1c-4f3b-b652-12e488ea88b5.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Antigua Guatemala Cathedral 4.5/5(427 reviews) After visiting Antigua Guatemala Cathedral, make a plan to see the other sights and activities in Antigua Guatemala. Discover the area's volcano viewpoints, or seek out its local tours. [](https://expedia.com/Antigua-Guatemala-Cathedral-Historic-Center.d6266484.Vacation-Attraction) ![Antigua, Guatemala, volcano](https://images.trvl-media.com/place/6105464/d466ff39-ee07-4e6d-baed-58b1a51c8314.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Central Park 4.5/5(503 reviews) Enjoy the volcano viewpoints and explore Central Park, a lovely green space in Antigua Guatemala. Discover the area's shops, or seek out its local tours. [](https://expedia.com/Central-Park-Historic-Center.d6105464.Vacation-Attraction) ![Recent trip to Antigua, Guatemala.](https://images.trvl-media.com/place/180589/2b05b9ea-3f0a-4375-9661-84349dc65ef7.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Santa Catalina Arch 4.5/5(452 reviews) Find out about the history of Antigua Guatemala when you spend time at Santa Catalina Arch. Discover the volcano viewpoints and shops in this family-friendly area. [](https://expedia.com/Santa-Catalina-Arch-Historic-Center.d553248621532619480.Vacation-Attraction) ![ Traditional vase and jar at market in Antigua, Guatemala.](https://images.trvl-media.com/place/553248621532963883/3ec95ff3-7959-4920-bfc4-dfcbe0674a2f.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Antigua Market 4.5/5(435 reviews) During your trip to Antigua Guatemala, you can enjoy retail therapy at Antigua Market. Discover the volcano viewpoints in this romantic area, or enjoy its local tours. [](https://expedia.com/Antigua-Market-Antigua-Guatemala.d553248621532963883.Vacation-Attraction) ![A one of a kind facade ](https://images.trvl-media.com/place/180589/12305006-65ce-4369-af37-4e05b1482005.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### La Merced Church 4.5/5(303 reviews) After visiting La Merced Church, make a plan to see the other sights and activities in Antigua Guatemala. Discover the area's shops, or seek out its local tours. [](https://expedia.com/La-Merced-Church-Antigua-Guatemala.d6105472.Vacation-Attraction) ![Cerro de la Cruz Antigua Guatemala](https://images.trvl-media.com/place/553248635975478041/72941465-dbed-49b1-8a26-b0c021969c22.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Cerro de La Cruz 4.5/5(5 reviews) You can find out about the history of Antigua Guatemala when you stop by Cerro de La Cruz. Discover the area's volcano viewpoints, or seek out its local tours. [](https://expedia.com/Cerro-De-La-Cruz-Antigua-Guatemala.d553248635975478041.Vacation-Attraction) ### Things to do ![Antigua: ATV Guided Sunset Tour](https://mediaim.expedia.com/localexpert/48070707/8c6c8cbf-7de5-420d-9021-6857de969452.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Antigua: ATV Guided Sunset Tour $65 per adult **100%** of travellers recommend [](https://expedia.com/things-to-do/antigua-atv-guided-sunset-tour.a48070707.activity-details) ![Bean-to-Bar Chocolate Workshop in ChocoMuseo Antigua](https://mediaim.expedia.com/localexpert/1349162/b382efa8-7e62-4e5c-bba7-f781953123d3.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Bean-to-Bar Chocolate Workshop in ChocoMuseo Antigua $32 per adult **100%** of travellers recommend [](https://expedia.com/things-to-do/bean-to-bar-chocolate-workshop-in-chocomuseo-antigua.a1349162.activity-details) ![From Antigua: 2-Day Acatenango Volcano Hiking Tour with Food](https://mediaim.expedia.com/localexpert/4750118/bc93a073-7009-4fd6-aa72-9db283ab8399.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### From Antigua: 2-Day Acatenango Volcano Hiking with Guide $55 per adult [](https://expedia.com/things-to-do/from-antigua-2-day-acatenango-volcano-hiking-with-guide.a4750118.activity-details) ![Picture 5 for Activity From Antigua: Pacaya Volcano Trek](https://mediaim.expedia.com/localexpert/4752068/1c69856b-8dcc-4431-92dc-9f40f7df8804.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### From Antigua: Pacaya Volcano Trek $23 per adult **92%** of travellers recommend [](https://expedia.com/things-to-do/from-antigua-pacaya-volcano-trek.a4752068.activity-details) ![Hobbitenango & Antigua Shared Day Tour](https://mediaim.expedia.com/localexpert/2255375/f73dd6e7-1acd-4f4e-9f87-c3528edb2545.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Hobbitenango & Antigua Shared Day Tour $89 per adult [](https://expedia.com/things-to-do/hobbitenango-antigua-shared-day-tour.a2255375.activity-details) ![Overnight Adventure Hike Acatenango Volcano ](https://mediaim.expedia.com/localexpert/2879443/978ed169-84e9-4507-9115-9a5a66bcd866.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Overnight Adventure Hike Acatenango Volcano $85 per adult [](https://expedia.com/things-to-do/overnight-adventure-hike-acatenango-volcano.a2879443.activity-details) [See all activities in Antigua Guatemala](https://expedia.com/Things-To-Do-In-Antigua-Guatemala.d180589.Travel-Guide-Activities) --- ## Santa Ana Hotel Deals ![Barceló Guatemala City](https://images.trvl-media.com/lodging/1000000/10000/2500/2495/321f0a1f_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Barceló Guatemala City 7 Avenida 15-45, Zona 9 Guatemala City Guatemala $103 nightly $126 total Apr 26 - Apr 27 Total with taxes and fees Book a stay at this luxury hotel in Guatemala City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the pool in our ... 9.2/10 Wonderful! (3,259 reviews) My favorite place I like the beds View Reviewed on Mar 27, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F26%2F2026&endDate=4%2F27%2F2026&selected=2495&PinnedHotelID=2495&HadPinnedHotel=true®ionId=553248635975847775) ![Wyndham Garden Guatemala City](https://images.trvl-media.com/lodging/1000000/30000/26600/26567/7c46a4a4_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Wyndham Garden Guatemala City 1a Avenida 12-46 Zona 10 Guatemala City Guatemala $104 nightly $127 total Apr 26 - Apr 27 Total with taxes and fees Book a stay at this business-friendly hotel in Guatemala City. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful ... 9.2/10 Wonderful! (1,727 reviews) was clean spacious and super perfect, will recommend this to anyone whose visiting. Reviewed on Mar 22, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F26%2F2026&endDate=4%2F27%2F2026&selected=26567&PinnedHotelID=26567&HadPinnedHotel=true®ionId=553248635975847775) ![Adriatika Hotel & Residence](https://images.trvl-media.com/lodging/9000000/8340000/8336300/8336251/9c9c2090_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Adriatika Hotel & Residence 4 av 20-44 Zona 14 Guatemala City Guatemala Fully refundableReserve now, pay when you stay $96 nightly $117 total Apr 10 - Apr 11 Total with taxes and fees Book a stay at this luxury hotel in Guatemala City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean ... 9.4/10 Exceptional! (1,007 reviews) This is a wonderful hotel, and I plan to return in future visits to Guatemala. Reviewed on Mar 25, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F10%2F2026&endDate=4%2F11%2F2026&selected=8336251&PinnedHotelID=8336251&HadPinnedHotel=true®ionId=553248635975847775) ![Porta Hotel Antigua](https://images.trvl-media.com/lodging/1000000/10000/5600/5545/da5ce8e0_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Porta Hotel Antigua 8va Calle Poniente No1 Antigua Guatemala Sacatepequez $185 nightly $226 total Apr 6 - Apr 7 Total with taxes and fees Book a stay at this luxury hotel in Antigua Guatemala. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the clean ... 9.4/10 Exceptional! (1,000 reviews) Can't go wrong with this hotel, staff is great. Reviewed on Mar 24, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F6%2F2026&endDate=4%2F7%2F2026&selected=5545&PinnedHotelID=5545&HadPinnedHotel=true®ionId=553248635975847775) ![Hotel La Galeria](https://images.trvl-media.com/lodging/31000000/30670000/30663400/30663346/28f70b81_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel La Galeria 7ma calle poniente # 43 Antigua Guatemala Sacatepequez $50 nightly $63 total Apr 13 - Apr 14 Total with taxes and fees Stay at this hotel in Antigua Guatemala. Enjoy free WiFi, room service, and parking (surcharge). Our guests praise the helpful staff in our reviews. Popular ... 9.4/10 Exceptional! (276 reviews) Clean Reviewed on Mar 24, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F13%2F2026&endDate=4%2F14%2F2026&selected=30663346&PinnedHotelID=30663346&HadPinnedHotel=true®ionId=553248635975847775) ![Hotel Camino Real Antigua](https://images.trvl-media.com/lodging/4000000/3090000/3085000/3084914/e88ac778_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Camino Real Antigua 7a Calle Poniente 33B Antigua Guatemala Sacatepequez $175 nightly $221 total Apr 6 - Apr 7 Total with taxes and fees Book a stay at this spa hotel in Antigua Guatemala. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property ... 9.6/10 Exceptional! (1,001 reviews) Excellent hotel, highly recommend! Reviewed on Mar 24, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F6%2F2026&endDate=4%2F7%2F2026&selected=3084914&PinnedHotelID=3084914&HadPinnedHotel=true®ionId=553248635975847775) [See all 1,228 properties in Santa Ana](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=3%2F28%2F2026&endDate=3%2F29%2F2026®ionId=553248635975847775) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Santa Ana hotel availability [Tonight ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635975847775&startDate=2026-03-27&endDate=2026-03-28)[Mar 27 - Mar 28](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635975847775&startDate=2026-03-27&endDate=2026-03-28) [Tomorrow night ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635975847775&startDate=2026-03-28&endDate=2026-03-29)[Mar 28 - Mar 29](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635975847775&startDate=2026-03-28&endDate=2026-03-29) [This weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635975847775&startDate=3%2F27%2F2026&endDate=3%2F29%2F2026)[Mar 27 - Mar 29](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635975847775&startDate=3%2F27%2F2026&endDate=3%2F29%2F2026) --- ### Other neighborhoods around Santa Ana ![Cross and Volcan de Agua View From Cerro de la Cruz, Antigua, Sacatepequez Department, Guatemala](https://images.trvl-media.com/place/911356092010033152/29d5145e-703b-47ae-817d-6e4cfbcb485c.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Barrio de La Concepción While visiting Barrio de La Concepción, you might make a stop by sights like Casa Santo Domingo Museum and Jade Maya Factory and Museum. [](https://expedia.com/Antigua-Guatemala-Barrio-De-La-Concepcion.dx911356092010033152) ![Vue du volcan de Fuego](https://images.trvl-media.com/place/180589/dca320f5-d6f0-40d9-9f12-90c9c1ede687.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Historic Center While visiting Historic Center, you might make a stop by sights like Central Park and Santa Catalina Arch. [](https://expedia.com/Antigua-Guatemala-Historic-Center.dx911355684795535360) [See our Where To Stay guide](https://expedia.com/Antigua-Guatemala.dx180589.Where-To-Stay?rfrr=TG.LP.Dest.Neigh.Neighborhoods) --- --- - [Stays](?pwaLob=wizard-hotel-pwa-v2) - [Packages](?pwaLob=wizard-package-pwa) - [Flights](?pwaLob=wizard-flight-pwa) - [Things to do](?pwaLob=wizard-lx-pwa) - [Cruises](?pwaLob=wizard-cruise-pwa) - [Cars](?pwaLob=wizard-car-pwa) # Santa Ana ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app