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Compare 86 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Finca la Desa
Front of property

Finca la Desa

3.0 star property
$85 nightly
The price is $94
Jul 29 - Jul 30
Total includes taxes and fees
Finca la Desa
Hospedium Hotel Triana
Enjoy a drink at the hotel bar, where a selection of bottles and glasses are on display.

Hospedium Hotel Triana

3.0 star property
7.8 out of 10, Good, (19)
"Hotel en un poligono industrial"
$87 nightly
The price is $96
Jul 29 - Jul 30
Total includes taxes and fees
Hospedium Hotel Triana
Finca El Azahar
Relax by the serene pool surrounded by lush greenery and rolling hills.

Finca El Azahar

3.0 star property
10.0 out of 10, Exceptional, (5)
"Stunning, warm, beautiful, "
$216 nightly
The price is $238
Jul 31 - Aug 1
Total includes taxes and fees
Finca El Azahar
Hotel Villa de Berzocana
Relax in a cozy space with a brick column, bar area, and wooden tables.

Hotel Villa de Berzocana

3.0 star property
8.8 out of 10, Excellent, (16)
"Pub and restaurant on site very flexible with menu"
Hotel Villa de Berzocana
Hospedium Hotel Soterraña
Stunning lobby with a central staircase, patterned wallpaper, and elegant seating area.

Hospedium Hotel Soterraña

3.0 star property
8.6 out of 10, Excellent, (35)
"Kostenloser Parkplatz und Sauberkeit sind positiv hervorzuheben. Der Ort bietet so gut eie nichts. Wir waren im Nebengebäude untergebracht. Man kommt sich abgeschoben vor, weil es Personal und Frühstück nur im Haupthaus auf der anderen Straßenseite gibt. Das Zimmer war sehr dunkel (dunkle Einrichtung, kleines Fenster, unzureichendes Lampenlicht). Abendessen gibt es erst ab 20.00 Uhr. "
$73 nightly
The price is $81
Jul 29 - Jul 30
Total includes taxes and fees
Hospedium Hotel Soterraña
Hostal León
Stroll through a serene garden surrounded by vibrant flowers and lush greenery.

Hostal León

2.0 star property
7.6 out of 10, Good, (50)
"El personal amable, la habitación normal, muy tranquilo y silencioso. Me gustaría que hubiese habido secador para el pelo "
$59 nightly
The price is $65
Jul 29 - Jul 30
Total includes taxes and fees
Hostal León
Hotel Izan Trujillo
Experience the classic charm of our lobby, featuring arched ceilings and stone columns, perfect for dining or socializing.

Hotel Izan Trujillo

4.0 star property
8.8 out of 10, Excellent, (200)
"Ok"
$79 nightly
The price is $87
Jul 31 - Aug 1
Total includes taxes and fees
Hotel Izan Trujillo
Hostal Hueso
Enjoy a traditional dining experience with a long table set for a meal, surrounded by classic chairs and stonework walls.

Hostal Hueso

2.0 star property
8.0 out of 10, Very Good, (20)
$64 nightly
The price is $70
Jul 29 - Jul 30
Total includes taxes and fees
Hostal Hueso
Plaza Sandra
Experience the charm of a rustic interior with a vaulted ceiling and stone columns, featuring a dark wooden door and a shelf with a potted plant.

Plaza Sandra

3.0 star property
9.6 out of 10, Exceptional, (51)
"Clean and very nice, great communication from host"
Plaza Sandra
Alojamientos Plaza Mayor
Welcome to Pension Plaza Mayor, where guests can enjoy dining at Bicochet Restaurante.

Alojamientos Plaza Mayor

3.0 star property
8.0 out of 10, Very Good, (55)
"Susana was very friendly and wait for us to give us the keys. Great location in front of main plaza. Basic room, very clean. Room was located in third floor, no elevator. Overall very good experience "
$63 nightly
The price is $70
Jul 29 - Jul 30
Total includes taxes and fees
Alojamientos Plaza Mayor
Eurostars Palacio Santa Marta
Relax by the rectangular pool surrounded by a tiled deck and lounge chairs.

Eurostars Palacio Santa Marta

4.0 star property
9.2 out of 10, Wonderful, (312)
"Just excellent, Service from all staff is perfect "
$76 nightly
The price is $83
Aug 27 - Aug 28
Total includes taxes and fees
Eurostars Palacio Santa Marta
Parador de Trujillo
Walk through a historic corridor lined with cabinets and a table lamp, leading to a doorway.

Parador de Trujillo

4.0 star property
9.0 out of 10, Wonderful, (209)
"Like all the Parador hotels in which we stayed , the building ( which was previously a convent ) had lots of character and charm. Very comfortable room , and great location , within easy walking distance of the Plaza Mayor.Would happily;y stay here again. ."
$80 nightly
The price is $89
Aug 28 - Aug 29
Total includes taxes and fees
Parador de Trujillo
Casa Rural Las Canteras
Enjoy meals in this charming dining area with a long table, checkered tablecloth, and comfortable seating.

Casa Rural Las Canteras

3.0 star property
8.2 out of 10, Very Good, (33)
$95 nightly
The price is $105
Jul 29 - Jul 30
Total includes taxes and fees
Casa Rural Las Canteras
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Santa Cruz de la Sierra

Head to Juan Pizarro de Orellana Palace and Plaza Mayor—just two of the sights around Santa Cruz de la Sierra.

See all hotels in Santa Cruz de la Sierra

Top Santa Cruz de la Sierra Hotel Reviews

Parador de Trujillo

Parador de Trujillo

10/10 Excellent
"Love the paradores! Really enjoyed the pool and we had a wonderful dinner in the restaurant. Staff is very friendly and love the ambiance of the property. "
Annette 1-night trip
Posted 1 month ago
Parador de Trujillo

Frequently asked questions

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How much is the nightly rate at a Santa Cruz de la Sierra hotel?
Prices for hotels in Santa Cruz de la Sierra often vary, but you can find a great deal from $65 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.