Puerto de Santa Cruz Vacations from $1,443

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $2,000 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

The Latest Puerto de Santa Cruz vacation packages

Price found within the past 48 hours. Click for updated prices.
Hotel Riu Plaza España

Hotel Riu Plaza España

4 out of 5
Madrid Centro
Price was $2,120, price is now $1,443 per person
$1,443
per person
Jul 11 - Jul 17
found 1 hour ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Madrid (MAD)
9.4/10 Exceptional! (4,787 reviews)
A unique service. At the entrance Luis a nice and prepare to help us at every moment. As previous guest at Riu in Guadalajara Mexico. By far the best experience. Next time in Spain, Riu Plaza Espana will be our choice

Reviewed on May 1, 2026

Hostal Met Madrid

Hostal Met Madrid

1 out of 5
Madrid Centro
Save 100% on your flight
Price was $3,013, price is now $1,930 per person
$1,930
per person
Jun 7 - Jun 13
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Madrid (MAD)
9.2/10 Wonderful! (284 reviews)
Hostal limpio, remodelado, bien ubicado, seguro y con personal amable.

Reviewed on Apr 14, 2026

Main Street Madrid

Main Street Madrid

3 out of 5
Madrid Centro
Price was $2,203, price is now $1,510 per person
$1,510
per person
Jun 8 - Jun 13
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Madrid (MAD)
8.6/10 Excellent! (259 reviews)
Very nice hotel and staff. It was a bit hard to find so that’s why I rated it 4 instead of 5 stars. It’s on the 5th floor btw. Also the bathroom smelled like sewage a few times coming from the drain, but it cleared on its own. Great location also!

Reviewed on Apr 29, 2026

Casa Faraona Luxury Residences

Casa Faraona Luxury Residences

4 out of 5
Salamanca
Price was $4,008, price is now $2,842 per person
$2,842
per person
Jul 19 - Jul 25
found 20 hours ago
Roundtrip flight included
Miami (MIA) to Madrid (MAD)
9.6/10 Exceptional! (46 reviews)
Spatious, modern and elegant with an excellent location.

Reviewed on Apr 10, 2026

Relais & Châteaux Hotel Orfila

Relais & Châteaux Hotel Orfila

5 out of 5
Chamberí
Save 100% on your flight
Price was $3,317, price is now $2,372 per person
$2,372
per person
Jun 19 - Jun 24
found 1 day ago
Roundtrip flight included
New York (JFK) to Madrid (MAD)
9.8/10 Exceptional! (571 reviews)
Friendly staff, beautiful hotel

Reviewed on Apr 27, 2026

Don't see what you're looking for?
See all available trips from Columbus to Puerto de Santa Cruz
View all trips

Puerto de Santa Cruz Hotel Deals

Parador de Trujillo

Parador de Trujillo

4 out of 5
Santa Beatriz de Silva 1 Trujillo Caceres
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $98 total per night from May 3 to May 4
$98 total
May 3 - May 4
Total with taxes and fees
9.2/10 Wonderful! (227 reviews)
Very nice hotel, good parking, well located,

Reviewed on Nov 18, 2025

Parador de Trujillo
Eurostars Palacio Santa Marta

Eurostars Palacio Santa Marta

4 out of 5
Calle Ballesteros 6 Trujillo Caceres
Fully refundableReserve now, pay when you stay
$75 nightly
The price is $83 total per night from Jun 1 to Jun 2
$83 total
Jun 1 - Jun 2
Total with taxes and fees
9.2/10 Wonderful! (339 reviews)
Wonderful location. Friendly staff.

Reviewed on Mar 28, 2026

Eurostars Palacio Santa Marta
Finca la Desa

Finca la Desa

3 out of 5
Carretera Nacional 5 km. 293 Miajadas Cáceres
Fully refundableReserve now, pay when you stay
$78 nightly
The price is $86 total per night from May 3 to May 4
$86 total
May 3 - May 4
Total with taxes and fees
9.8/10 Exceptional! (9 reviews)
This is a diamond in the west country of Spain. Everything about this place was exceptional.

Reviewed on Mar 15, 2026

Finca la Desa
See all 89 properties in Puerto de Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Puerto de Santa Cruz Vacation Packages

Puerto de Santa Cruz Essential Information

Language
Spanish
Currency
Euros
Local Welcome
¡Hola!
Local Goodbye
Adiós
Population
410
Max Temp Winter
55ºF
Max Temp Summer
90ºF
Top Sights
Trujillo Castle, Juan Pizarro de Orellana Palace and Palace of the Marquis of the Conquest

More vacations you might like

All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Frequently asked questions

How much does a Puerto de Santa Cruz vacation package cost?
Offering great value package deals from $1,443 on Expedia, you'll be thrilled with how little a vacation to Puerto de Santa Cruz costs! Expedia's packages make travel planning easier and your savings go further.
What are the cheapest months to go to Puerto de Santa Cruz?
If you'd like to snag a cheap Puerto de Santa Cruz vacation package, consider planning a trip in February, November and December. You'll usually find better rates on flights and hotels during these months — perfect for travelers wishing to save money.
How many days is enough for Puerto de Santa Cruz?
Typically, a handful of days is enough to go to the main sights during your Puerto de Santa Cruz vacation. But if you'd like to have some time to relax or take day trips, consider extending your trip.
How to find the best Puerto de Santa Cruz package deals?
Start your search for a Puerto de Santa Cruz package deal by entering your destination and preferred trip dates under our "Packages" tab. Then apply some filters, like "Popular locations" and "Property type," to fine-tune the results to your exact needs. You can also sort by "Package discount" and discover offers that come with big savings. If you don't find the perfect Puerto de Santa Cruz package deal right away, simply play around with your dates and search again. Keep in mind that deals are only available for a limited time, so book early and get your Puerto de Santa Cruz adventure underway.
Is it cheaper to book a Puerto de Santa Cruz vacation as a package?
An Expedia vacation package could land you great savings when compared to arranging flights and accommodations separately. Better still, you can tailor your Puerto de Santa Cruz getaway to match your exact style. Pick your preferred flight time, select the hotel type and add a car rental. Check out our great deals to see how much you can save.
When to book a vacation package to Puerto de Santa Cruz?
If you have your Puerto de Santa Cruz vacation dates finalized, book early to snap up some outstanding deals. With Expedia, you can typically reserve some flights up to one year ahead of time. Prefer spur-of-the-moment getaways? Our last-minute deals are perfect for jetting off on a whim.
Does Expedia offer Book Now, Pay Later Puerto de Santa Cruz vacation packages?
Set off on your dream escape to Puerto de Santa Cruz with our Book Now, Pay Later vacations. No need to save like crazy or wait until payday — we've joined forces with online lender Affirm to offer you flexibility with your finances. Our vacation packages with payment plans let you spread the cost across 3, 6 or 12 months. With no hidden or late payment fees, you can easily budget for your trip and snap up travel deals before they sell out.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.