Name: Hotel Alfonso XIII, a Luxury Collection Hotel, Seville
Price range: $676 total

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Your Santa Cruz Vacation

Booking a Santa Cruz vacation package is a good way to become acquainted with this unique neighborhood. From its must-visit places to its lesser-known treasures, there's a lot to delve into. Some leading nearby attractions to check out during your trip to Santa Cruz include Seville Cathedral, Alcázar and Plaza de España. Whatever your dream Santa Cruz vacation looks like, you can turn it into reality with Expedia.

The Latest Santa Cruz Vacation Packages

Price found within the past 48 hours. Click for updated prices.

Hotel ILUNION Alcora Sevilla

$372

per person

Dec 9 - Dec 13

found 8 hours ago

Roundtrip flight included

Madrid (MAD) to Seville (SVQ)

8.6/10 Excellent! (1,004 reviews)

Welldone Quality - Crystal Pool

Historical Center

$466

per person

Dec 9 - Dec 13

found 8 hours ago

Roundtrip flight included

Madrid (MAD) to Seville (SVQ)

9.2/10 Wonderful! (419 reviews)

La propiedad está en el casco histórico, cerca del centro de todo.” M u

Reviewed on Oct 25, 2026

Aguilas5 SevillaSuites

Historical Center

$1,203

per person

Jan 19 - Jan 23

found 1 day ago

Roundtrip non-stop flight included

New York (JFK) to Seville (SVQ)

10/10 Exceptional! (532 reviews)

Perfect location in central area of Seville , staff were wonderful and exceptionally helpful. Accommodation had all the amenities needed and was lovely and perfect for a stay . Will definitely use again.

Reviewed on Oct 24, 2026

Hotel Boutique Casa del Limonero - Adults only

Historical Center

$2,483

per person

Dec 20 - Dec 27

found 10 hours ago

Roundtrip non-stop flight included

New York (JFK) to Seville (SVQ)

10/10 Exceptional! (98 reviews)

Casa de Triana Luxury Suites by Casa del Poeta

Triana

$2,723

per person

Dec 20 - Dec 27

found 1 day ago

Roundtrip non-stop flight included

New York (NYC) to Seville (SVQ)

10/10 Exceptional! (445 reviews)

We would highly recommend this place!! The staff and customer service was wonderful. The place was immaculate and luxurious. We had beautiful decks , a perfect location. A wonderful breakfast was delivered directly to our door.

Reviewed on Oct 14, 2026

Where to stay in Santa Cruz

Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most. Learn more about Santa Cruz

A tree-lined street with parked motorcycles and cars, and a person walking.

Historical Center

8 out of top 10 points of interest in this area

Go on an adventure through the ages when you visit the historical churches, palaces, plazas and mansions of Seville’s ancient heart.

Santa Cruz Hotel Deals

Las Casas de la Judería, Sevilla Historic City Center

Calle Santa Maria La Blanca 5 Seville Seville

Fully refundableReserve now, pay when you stay

$110 nightly

$121 total

Nov 30 - Dec 1

Total with taxes and fees

9.2/10 Wonderful! (1,026 reviews)

"Beautiful, unique property in an excellent area close to all of the beauty of Sevilla!"

Reviewed on Oct 29, 2026

Hotel Amadeus Sevilla

Calle Farnesio 6 Seville Seville

Fully refundableReserve now, pay when you stay

$131 nightly

$144 total

Nov 22 - Nov 23

Total with taxes and fees

9.6/10 Exceptional! (1,295 reviews)

"Beautiful hotel in great location."

Reviewed on Oct 29, 2026

Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

San Fernando 2 Seville Seville

Fully refundableReserve now, pay when you stay

$614 nightly

$676 total

Nov 30 - Dec 1

Total with taxes and fees

See all 412 properties in Santa Cruz

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.