Santa Cruz

Seville

Santa Cruz showing street scenes as well as a couple
Cabildo Catedral which includes heritage architecture, a church or cathedral and a square or plaza
Santa Cruz
Seville Cathedral showing religious aspects, a church or cathedral and a city
Santa Cruz featuring heritage elements and street scenes as well as a small group of people
Wander through a maze of cobbled streets in one of Seville's most picturesque areas, an ancient neighborhood that's home to major landmarks and medieval buildings.

Santa Cruz is one of the oldest neighborhoods in the city. The former medieval Jewish quarter is known for its squares framed by orange trees, narrow streets that keep out the sun, whitewashed homes adorned by flower-filled balconies and Seville's main monuments, the cathedral and the Giralda. Visit Santa Cruz on foot and discover insights into its long and fascinating past.

Nestled in the heart of the neighborhood or barrio is the 15th-century Seville Cathedral, a massive gothic structure that is one of the largest churches in the world. Marvel at centuries-old frescoes that adorn chapels, visit the tomb of explorer Christopher Columbus and climb up the bell tower, the Giralda. This was the tallest building in the city for hundreds of years, and its oldest part is a minaret from the 12th century.

Then walk over to the 14th-century mudejar-style Royal Alcazar of Seville, which is still used by the Spanish royal family when they're in the city.

Meander down extremely narrow pedestrianized streets called kissing lanes because the houses on opposite sides are so close. The streets were designed like this to maximize shade. Pause to admire tiled patios of mansions and townhouses through their wrought-iron gates.

Visit the Casa Fabiola for its collection of paintings, sculptures and religious pieces. Adjoining this renaissance Sevillian palace is a section of the wall that encircled the old Jewish quarter.

Trace the history of Seville's Jewish community by studying the artifacts and information panels at the Centro de Interpretación Judería de Sevilla.

Unwind in one of the beautiful squares that dot the neighborhood, such as Plaza Doña Elvira with its fountain, tiled benches and orange trees. Enjoy more tranquil moments in the Jardines de Murillo, a peaceful oasis of flowerbeds, fountains, arbors and magnolia trees, among other species.

Find the Santa Cruz neighborhood in the historic center of the city and enjoy its charm, beauty and atmosphere as you stroll through the cobblestone streets.


Popular places to visit

Things to do


Santa Cruz Hotel Deals

Las Casas de la Judería, Sevilla Historic City Center

Las Casas de la Judería, Sevilla Historic City Center

4 out of 5
Calle Santa Maria La Blanca 5 Seville Seville
$191 nightly
The price is $210 total per night from Mar 22 to Mar 23
$210 total
Mar 22 - Mar 23
Total with taxes and fees
Book a stay at this spa hotel in Seville. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the pool and the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,006 reviews)
This hotel is a gem. It's like they took old town and stuffed it into hotel. Just take a look at the pictures and you can see it's pretty magical. My room originally was too small for my liking (it literally was only as big as a foot and a half around the bed) but they happily switched me to a more ...

Reviewed on Mar 16, 2026

Las Casas de la Judería, Sevilla Historic City Center
Hotel Fernando III

Hotel Fernando III

4 out of 5
San Jose 21 Seville Seville
$219 nightly
The price is $241 total per night from Mar 23 to Mar 24
$241 total
Mar 23 - Mar 24
Total with taxes and fees
Book a stay at this business-friendly hotel in Seville. Enjoy free WiFi, an outdoor pool, and a rooftop terrace. Our guests praise the breakfast and the pool ...
9.6/10 Exceptional! (1,492 reviews)
Lovely hotel in a perfect location. Professional, courteous, friendly staff throughout. We had selected the cheapest room available which turned out to be spacious, clean, very well maintained/decorated. Included safe, hairdryer, mini fridge, daily bottles of water and toiletries. Complimentary bottle ...

Reviewed on Mar 16, 2026

Hotel Fernando III
Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

5 out of 5
San Fernando 2 Seville Seville
Fully refundableReserve now, pay when you stay
$655 nightly
The price is $721 total per night from Apr 14 to Apr 15
$721 total
Apr 14 - Apr 15
Total with taxes and fees
Book a stay at this luxury hotel in Seville. Enjoy 2 restaurants, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff in our ...
9.4/10 Exceptional! (1,002 reviews)
Staff

Reviewed on Feb 27, 2026

Hotel Alfonso XIII, a Luxury Collection Hotel, Seville
Hotel Rey Alfonso X

Hotel Rey Alfonso X

4 out of 5
Calle Ximenez De Enciso, 35 Seville Seville
$219 nightly
The price is $241 total per night from Mar 23 to Mar 24
$241 total
Mar 23 - Mar 24
Total with taxes and fees
Stay at this hotel in Seville. Enjoy free WiFi, an outdoor pool, and a rooftop terrace. Our guests praise the breakfast and the pool in our reviews. Popular ...
9.6/10 Exceptional! (1,143 reviews)
The hotel was great, and the staff was awesome, there was one young lady ( at the coun

Reviewed on Mar 14, 2026

Hotel Rey Alfonso X
Hotel Murillo

Hotel Murillo

2 out of 5
Calle Lope de Rueda, 7-9 Seville Seville
$130 nightly
The price is $143 total per night from Mar 26 to Mar 27
$143 total
Mar 26 - Mar 27
Total with taxes and fees
Book a stay at this family-friendly hotel in Seville. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.8/10 Excellent! (1,006 reviews)
Very good all round. Convenient for bars, restaurants and eating out. Great choice. Comfortable rooms with tea and coffee provided. Could have had breakfast but there were so many places nearby offering good breakfasts, so l ate out.

Reviewed on Mar 14, 2026

Hotel Murillo
Hotel Amadeus Sevilla

Hotel Amadeus Sevilla

4 out of 5
Calle Farnesio 6 Seville Seville
$208 nightly
The price is $229 total per night from Mar 22 to Mar 23
$229 total
Mar 22 - Mar 23
Total with taxes and fees
Book a stay at this boutique hotel in Seville. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the breakfast and the bar in ...
9.6/10 Exceptional! (1,163 reviews)
Very helpful reception staff and on the local area. Was low season so we only had to ask if needed anything for the room or drinks served in the lobby/bar

Reviewed on Mar 15, 2026

Hotel Amadeus Sevilla
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Santa Cruz

El Arenal showing street scenes as well as a small group of people

El Arenal

5/5(210 area reviews)

Located in Seville's historical center, El Arenal boasts the 13th-century Torre del Oro, Royal Shipyards, and La Real Maestranza bullring. Explore this vibrant area on the Guadalquivir river's east bank.

El Arenal
Metropol Parasol, Seville Spain. The largest wooden structure in the world. #BvsCities #UrbanJungle

San Bartolomé

Travelers come to San Bartolomé for its lively bars, and you can see top attractions like Pilate's House and Zurbarán Statue while you're in town.

San Bartolomé
Salvador Plaza showing outdoor eating as well as a small group of people

Alfalfa

Unique features of Alfalfa include the bars and historic sites. Make a stop by Salvador Plaza or Calle Sierpes while you're exploring the area.

Alfalfa
Historical Center

Historical Center

4.5/5(600 area reviews)

Casa de la Memoria Cultural Center and Calle Sierpes are a few top attractions in Historical Center. Hop around the city on the metro at Plaza Nueva Tram Stop or Archivo de Indias Tram Stop and check out the area's fantastic nightlife, stunning cathedral, and popular shops.

Historical Center
Inside the Moorish Royal Alcazar Palace in Seville, Spain

La Florida

The restaurants and shopping are a few reasons travelers visit La Florida. Want to see more of the surrounding area? Murillo Gardens and Pilate's House are a few top sights nearby.

La Florida
Default Image

San Bernardo

Even though there aren't top sights in San Bernardo, you can explore the larger area and take in top sights like Murillo Gardens. Jump on the metro at Prado San Sebastián Tram Stop to see more of the city.

San Bernardo


Santa Cruz

Choose one or more items to build your trip:

Explore a world of travel with Expedia