Santa Cruz

Seville

Santa Cruz showing street scenes as well as a couple
Cabildo Catedral which includes heritage architecture, a church or cathedral and a square or plaza
Santa Cruz
Seville Cathedral showing religious aspects, a church or cathedral and a city
Santa Cruz featuring heritage elements and street scenes as well as a small group of people
Wander through a maze of cobbled streets in one of Seville's most picturesque areas, an ancient neighborhood that's home to major landmarks and medieval buildings.

Santa Cruz is one of the oldest neighborhoods in the city. The former medieval Jewish quarter is known for its squares framed by orange trees, narrow streets that keep out the sun, whitewashed homes adorned by flower-filled balconies and Seville's main monuments, the cathedral and the Giralda. Visit Santa Cruz on foot and discover insights into its long and fascinating past.

Nestled in the heart of the neighborhood or barrio is the 15th-century Seville Cathedral, a massive gothic structure that is one of the largest churches in the world. Marvel at centuries-old frescoes that adorn chapels, visit the tomb of explorer Christopher Columbus and climb up the bell tower, the Giralda. This was the tallest building in the city for hundreds of years, and its oldest part is a minaret from the 12th century.

Then walk over to the 14th-century mudejar-style Royal Alcazar of Seville, which is still used by the Spanish royal family when they're in the city.

Meander down extremely narrow pedestrianized streets called kissing lanes because the houses on opposite sides are so close. The streets were designed like this to maximize shade. Pause to admire tiled patios of mansions and townhouses through their wrought-iron gates.

Visit the Casa Fabiola for its collection of paintings, sculptures and religious pieces. Adjoining this renaissance Sevillian palace is a section of the wall that encircled the old Jewish quarter.

Trace the history of Seville's Jewish community by studying the artifacts and information panels at the Centro de Interpretación Judería de Sevilla.

Unwind in one of the beautiful squares that dot the neighborhood, such as Plaza Doña Elvira with its fountain, tiled benches and orange trees. Enjoy more tranquil moments in the Jardines de Murillo, a peaceful oasis of flowerbeds, fountains, arbors and magnolia trees, among other species.

Find the Santa Cruz neighborhood in the historic center of the city and enjoy its charm, beauty and atmosphere as you stroll through the cobblestone streets.


Popular places to visit

Things to do


Santa Cruz Hotel Deals

Las Casas de la Judería, Sevilla Historic City Center

Las Casas de la Judería, Sevilla Historic City Center

4 out of 5
Calle Santa Maria La Blanca 5 Seville Seville
$112 nightly
The price is $123 total per night from Feb 1 to Feb 2
$123 total
Feb 1 - Feb 2
Total with taxes and fees
Book a stay at this spa hotel in Seville. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the pool and the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,008 reviews)
The hotel is very unique and interesting, feels like it’s a museum. The staff member is fine, the room is clean but a little old.

Reviewed on Jan 4, 2026

Las Casas de la Judería, Sevilla Historic City Center
Hotel Amadeus Sevilla

Hotel Amadeus Sevilla

4 out of 5
Calle Farnesio 6 Seville Seville
$122 nightly
The price is $135 total per night from Jan 11 to Jan 12
$135 total
Jan 11 - Jan 12
Total with taxes and fees
Book a stay at this boutique hotel in Seville. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the breakfast and the bar in ...
9.6/10 Exceptional! (1,115 reviews)
Very nice room, excellent staff and nice position

Reviewed on Jan 5, 2026

Hotel Amadeus Sevilla
Hotel Fernando III

Hotel Fernando III

4 out of 5
San Jose 21 Seville Seville
$109 nightly
The price is $120 total per night from Jan 11 to Jan 12
$120 total
Jan 11 - Jan 12
Total with taxes and fees
Book a stay at this business-friendly hotel in Seville. Enjoy free WiFi, an outdoor pool, and a rooftop terrace. Our guests praise the breakfast and the pool ...
9.6/10 Exceptional! (1,532 reviews)
We stayed at this hotel over Christmas. We found it well located to explore the city centre and the staff were friendly and helpful.The breakfasts were excellent and even included Bucks Fizz!

Reviewed on Jan 5, 2026

Hotel Fernando III
Hotel Rey Alfonso X

Hotel Rey Alfonso X

4 out of 5
Calle Ximenez De Enciso, 35 Seville Seville
Fully refundableReserve now, pay when you stay
$117 nightly
The price is $129 total per night from Jan 27 to Jan 28
$129 total
Jan 27 - Jan 28
Total with taxes and fees
Stay at this hotel in Seville. Enjoy free WiFi, an outdoor pool, and a rooftop terrace. Our guests praise the breakfast and the pool in our reviews. Popular ...
9.4/10 Exceptional! (1,127 reviews)
Loved it! Could hace stayed there a few more days for sure! Excellent location, parking available, walikng distance to just about everything! Laundry conveniently located right across the street, but we did not need to use it.

Reviewed on Dec 30, 2025

Hotel Rey Alfonso X
Hotel Murillo

Hotel Murillo

2 out of 5
Calle Lope de Rueda, 7-9 Seville Seville
$56 nightly
The price is $61 total per night from Jan 13 to Jan 14
$61 total
Jan 13 - Jan 14
Total with taxes and fees
Book a stay at this family-friendly hotel in Seville. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.6/10 Excellent! (1,000 reviews)
Warm welcoming staff and clean rooms . Close to many fine restaurants

Reviewed on Dec 25, 2025

Hotel Murillo
Hotel Boutique Casa del Poeta Sevilla

Hotel Boutique Casa del Poeta Sevilla

4 out of 5
Don Carlos Alonso Chaparro 3 Seville Seville
$198 nightly
The price is $217 total per night from Feb 8 to Feb 9
$217 total
Feb 8 - Feb 9
Total with taxes and fees
Book a stay at this boutique hotel in Seville. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the property ...
9.6/10 Exceptional! (871 reviews)
Fantastic property and staff. We spent 7 night here and it was perfect.

Reviewed on Jan 4, 2026

Hotel Boutique Casa del Poeta Sevilla
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Santa Cruz

El Arenal showing street scenes as well as a small group of people

El Arenal

5/5(210 area reviews)

Located in Seville's historical center, El Arenal boasts the 13th-century Torre del Oro, Royal Shipyards, and La Real Maestranza bullring. Explore this vibrant area on the Guadalquivir river's east bank.

El Arenal
The third biggest cathedral of the world, you could say the 12th century Moord succeeded quite well in building the world's biggest cathedral. It's beautiful and grand, inside and out.

San Bartolomé

Travelers come to San Bartolomé for its lively bars, and you can see top attractions like Pilate's House and Zurbarán Statue while you're in town.

San Bartolomé
Salvador Plaza showing outdoor eating as well as a small group of people

Alfalfa

Unique features of Alfalfa include the bars and historic sites. Make a stop by Salvador Plaza or Calle Sierpes while you're exploring the area.

Alfalfa
Historical Center

Historical Center

4.5/5(600 area reviews)

Casa de la Memoria Cultural Center and Calle Sierpes are a few top attractions in Historical Center. Hop around the city on the metro at Plaza Nueva Tram Stop or Archivo de Indias Tram Stop and check out the area's fantastic nightlife, stunning cathedral, and popular shops.

Historical Center
Metropol Parasol, Seville Spain. The largest wooden structure in the world. #BvsCities #UrbanJungle

La Florida

The restaurants and shopping are a few reasons travelers visit La Florida. Want to see more of the surrounding area? Murillo Gardens and Pilate's House are a few top sights nearby.

La Florida
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San Bernardo

Even though there aren't top sights in San Bernardo, you can explore the larger area and take in top sights like Murillo Gardens. Jump on the metro at Prado San Sebastián Tram Stop to see more of the city.

San Bernardo


Santa Cruz

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