Santa Fe Vacations from $408

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Your Santa Fe Vacation

Experience everything Santa Fe has to offer with a customized Santa Fe vacation package. From its cafes and shopping to its dining, it's not hard to be charmed by this food-lovers neighborhood. Start your trip to Santa Fe by checking out nearby attractions such as Paseo Interlomas, Santa Fe Center Mall and Anahuac University. Stop daydreaming and start doing. When it's time to lock in your vacation to Santa Fe, Expedia will help get you there.

The Latest Santa Fe Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hostal Amigo - Hostel

Hostal Amigo - Hostel

Historic Center
$408
per person
Sep 14 - Sep 18
found 1 day ago
Roundtrip flight included
Dallas (DFW) to Mexico City (MEX)
7.6/10 Good! (374 reviews)
Hacienda Peña Pobre

Hacienda Peña Pobre

Tlalpan
Save 100% on your flight
$747
per person
Sep 12 - Sep 18
found 1 day ago
Roundtrip flight included
Dallas (DFW) to Mexico City (MEX)
9.6/10 Exceptional! (824 reviews)
Colima 71 Casa de Arte Hotel

Colima 71 Casa de Arte Hotel

Roma Norte
$1,320
per person
Sep 18 - Sep 23
found 1 day ago
Roundtrip flight included
Los Angeles (LAX) to Mexico City (MEX)
9.8/10 Exceptional! (51 reviews)
Casa Decu

Casa Decu

La Condesa
Save 100% on your flight
$963
per person
Nov 2 - Nov 9
found 1 day ago
Roundtrip flight included
Dallas (DFW) to Mexico City (MEX)
9.4/10 Exceptional! (1,005 reviews)
Everything was wonderful! I appreciated that we were able to get into our room as soon as it was ready, since we'd had an early day of travel and were hoping to take a quick nap before starting our trip. Our hotel room was tidy and spacious. I loved that we had a space to place our luggage as well as plenty of closet space. The security helped make the space feel extra safe, even though La Condesa is already an incredibly safe and walkable area. I recommend checking out Mendl Delicatessen nearby! The only downside was having our room be on the fourth floor and walking up those flights of stairs after long days. Otherwise, it was a perfect stay!

Reviewed on Aug 10, 2026

Hotel Luca

Hotel Luca

Roma Norte
Save 100% on your flight
$1,164
per person
Nov 2 - Nov 9
found 1 day ago
Roundtrip flight included
Dallas (DFW) to Mexico City (MEX)
9.2/10 Wonderful! (412 reviews)

Things to do in and around Santa Fe

Santa Fe, Mexico, offers a vibrant mix of activities perfect for family, business, and city-themed vacations. Visitors can explore friendly attractions, indulge in history tours, and enjoy various family activities. Don't miss the shopping mall center and local shopping areas for a delightful retail experience. For relaxation, spa services are also available, ensuring a well-rounded visit to this charming city.

Shopping

Experience shopping in Santa Fe at the Santa Fe Center Mall, boasting a vibrant atmosphere with entertainment and family-friendly options. Just 3 miles away, Paseo Interlomas offers more shopping and fun, while Bazar del Sabado, located 5 miles from Santa Fe, presents a unique public market experience.

Recreation

Blue Stadium offers an energetic atmosphere perfect for sports enthusiasts, just 6 miles from Santa Fe. Experience culture and entertainment at the Insurgentes Theater, located 5 miles away, ideal for a romantic night out. Enjoy the outdoors at Cuernavaca Country Club, also 5 miles from Santa Fe, with scenic golfing opportunities.

Adventure

Experience the excitement at KidZania Santa Fe, where kids can engage in fun role-playing activities in a vibrant arcade environment. For thrill-seekers, K1 Speed Mexico Garden offers exhilarating kart racing. Don't miss KBR Kartódromo Internacional, located 4 miles away, for an adrenaline-pumping racing experience.

Nightlife

Santa Fe's nightlife offers a vibrant mix of upscale lounges and lively bars. Enjoy cocktails at the chic Hotel Santa Fe, or dance the night away at La Santa. For a more laid-back vibe, visit the cozy Cafe de la Plaza for drinks and live music.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Find the best attractions near Santa Fe

Santa Fe offers a vibrant mix of urban attractions perfect for city-themed, family, or business vacations. Visitors can explore urban parks, event and conference venues, and modern colleges, making it an ideal destination for those seeking cultural experiences and family-friendly activities. Whether you're interested in the local culture or simply enjoying the city atmosphere, Santa Fe has something for everyone.

  • World Trade Center Mexico City: Experience the vibrant energy of this iconic skyscraper, which offers stunning panoramic views of the city from its observation deck. The surrounding area is filled with shopping, dining, and cultural experiences, making it a perfect spot to immerse yourself in the local lifestyle.
  • Frida Kahlo Museum: Step into the world of the renowned artist Frida Kahlo at this historic house, which showcases her life and work. The museum is filled with personal artifacts and colorful displays, providing a deep dive into her unique artistic vision and the cultural context of Mexico.
  • Auditorio Nacional: Enjoy an exhilarating experience at this premier entertainment venue, known for hosting concerts, operas, and cultural events. Its impressive architecture and acoustics make it a must-visit for families and entertainment enthusiasts alike.

Best time to go to Santa Fe

The best time to visit Santa Fe can depend on the weather and when visitor numbers rise and fall. The hottest average temperature around Santa Fe falls in May, when visitor numbers are slightly high and weather is sunny with no rain. The coolest average temperature around Santa Fe falls in January, visitor numbers are slightly low and weather is sunny with no rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January57.7°F (14.3°C)No RainSunnySlightly LowAverage
February61.3°F (16.3°C)No RainSunnyAverageSlightly High
March64.8°F (18.2°C)No RainSunnySlightly HighAverage
April67.6°F (19.8°C)No RainSunnyAverageAverage
May68.4°F (20.2°C)No RainSunnySlightly HighAverage
June65.3°F (18.5°C)Light RainMostly SunnyAverageAverage
July62.4°F (16.9°C)Moderate RainMostly SunnyAverageSlightly Low
August62.1°F (16.7°C)Moderate RainMostly SunnyAverageSlightly Low
September61.3°F (16.3°C)Light RainMostly SunnySlightly HighAverage
October60.4°F (15.8°C)Light RainMostly SunnySlightly LowSlightly High
November59.2°F (15.1°C)No RainSunnyAverageSlightly High
December58.5°F (14.7°C)No RainSunnySlightly LowSlightly Low

Tips to save on your trip to Santa Fe

  • Combine your flights, hotels and car rentals on Expedia—bundling can result in significant savings.
  • Consider traveling during the off-peak season (typically July to August and December) for more affordable package holidays to Santa Fe.
  • Use the Price per traveler filter on Expedia to find a package deal that suits your budget.
  • Check the VIP Access properties filter to discover outstanding hotels with added member perks at select properties.

Where to stay in Santa Fe

Find the best Santa Fe areas and neighborhoods for the activities you enjoy most. Learn more about Santa Fe
An aerial view of a city with a central circular plaza, surrounded by buildings and trees.

Roma Norte

Known for its fascinating museums and popular shops, there's plenty to explore in Roma Norte. Check out top attractions like Avenida Insurgentes and MUCA Roma, and jump on the metro at Insurgentes Station or Sevilla Station to see more of the city.

A large stone church with a central dome and arched entrance.

Polanco

Luxury shopping along Presidente Masaryk Avenue and upscale restaurants await, while nearby Chapultepec Park houses the National Museum of Anthropology and other cultural institutions. Enjoy a stroll in Parque Lincoln or explore Polanquito's vibrant dining scene.

A yellow building with a sign reading "El Jolgorio."

La Condesa

Fashionable and popular with young professionals, Condesa boasts international restaurants, bars, and nightclubs. Stroll along tree-lined avenues, admire Art Deco architecture, and visit landmarks like Edificio San Martín and Basurto Building.

A historic church with intricate architecture and a bell tower.

Historic Center

2 out of top 10 points of interest in this area

Historic center with 1,550 significant buildings, the neighborhood offers museums like MUNAL and Palacio de Bellas Artes. Enjoy upscale eateries, fashionable stores, and pedestrianized streets for easy exploration.

A city street at dusk with illuminated buildings, palm trees, and vehicles with light trails.

Reforma

1 out of top 10 points of interest in this area

Consider a visit to Angel of Independence Monument and take some time to enjoy the important monuments during your time in Reforma. If you want to see more of the city, jump on the metro at Insurgentes Station or Cuauhtemoc Station.

Santa Fe Hotel Deals

Barceló México Santa Fe

Barceló México Santa Fe

Mexico City
Fully refundableReserve now, pay when you stay
$93 nightly
$111 total
Aug 16 - Aug 17
Total with taxes and fees
Barceló México Santa Fe
Camino Real Aeropuerto Mexico

Camino Real Aeropuerto Mexico

Mexico City
Fully refundable
$136 nightly
$163 total
Sep 5 - Sep 6
Total with taxes and fees
8.8/10 Excellent! (13,686 reviews)
"Terrible service, for being a “5 star hotel “ the place was very old the room temperature was hot and couldn’t be changed also room service was poor. Only good side of this hotel is being connected to the airport other than that I do not recommend to stay here for the price."

Reviewed on Aug 13, 2026

Camino Real Aeropuerto Mexico
Hotel Zócalo Central

Hotel Zócalo Central

Cinco de Mayo 61 Mexico City
Fully refundableReserve now, pay when you stay
$164 nightly
$197 total
Sep 10 - Sep 11
Total with taxes and fees
Hotel Zócalo Central
See all 5,682 properties in Santa Fe
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Santa Fe attractions

A cityscape with modern high-rise buildings, a green park area, and a complex road network.

Parque La Mexicana

9.6/10 (18 reviews)
After visiting Parque La Mexicana, make a plan to see the other sights and activities in Mexico City. Make time to visit the area's shops, or simply enjoy its top-notch restaurants.
See properties
A cityscape with modern high-rise buildings, a construction crane, and a mix of greenery and urban development.

Arcos Bosques

8.4/10 (23 reviews)
During your trip to Mexico City, you can do some window-shopping at Arcos Bosques. Check out the stunning cathedral and top-notch restaurants in this culturally rich area.
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Santa Fe Center Mall

9.0/10 (104 reviews)
During your trip to Mexico City, you can find the perfect gifts to bring home at Santa Fe Center Mall. Discover the top-notch restaurants and great live music in this vibrant area.
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Tecnologico de Monterrey - Santa Fe

9.0/10 (12 reviews)
Walk around the campus at Tecnologico de Monterrey - Santa Fe during your visit to Mexico City. Discover the top-notch restaurants and fascinating museums in this vibrant area.
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Expo Santa Fe Mexico

9.2/10 (17 reviews)
After visiting Expo Santa Fe Mexico, make a plan to see the other sights and activities in Mexico City. Visit the stunning cathedral and shops in this culturally rich area.
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Ciudad de los Ninos

Enjoy an outing to Ciudad de los Ninos during your stay in Mexico City. Discover the acclaimed art scene and stunning cathedral in this vibrant area.
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Samara Shops

10.0/10 (4 reviews)
You can enjoy retail therapy at Samara Shops during your trip to Mexico City. Make time to visit the area's shops, or simply enjoy its top-notch restaurants.
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K1 Speed ​​Mexico Garden Santa Fe

You can take time to visit K1 Speed ​​Mexico Garden Santa Fe during your travels to Mexico City. Make time to visit the area's shops, or simply enjoy its top-notch restaurants.
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Things to do

Admission to Six Flags Mexico with roundtrip transportation

Admission to Six Flags Mexico with roundtrip transportation

$98
per adult
100% of travellers recommend
Admission to Six Flags Mexico with roundtrip transportation
MEXICAN WRESTLING TOUR WITH TACOS AFTER SHOW N MEXICO CITY

Lucha Libre Mexican Wrestling Tour in Mexico City

$62
per traveler
100% of travellers recommend
Lucha Libre Mexican Wrestling Tour in Mexico City
See all activities in Mexico City

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.