Santee Vacation Rentals

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Vacation Rentals in Santee

Retreat near the Lake and State Parks of Yankton
9.2 out of 10, Wonderful, (11)
"Thank you so much for all you did for us...we so appreciate it! We only stayed one night, as a bad storm was headed in, so we opted to head home early, just in case! Thanks again!!"
Retreat near the Lake and State Parks of Yankton
Shady Creek Cabin - Family Friendly Getaway Near Lake
10.0 out of 10, Exceptional, (55)
"We loved the location and the property! Everything we needed was there. Communication with the owners was very good and they were very responsive to any questions . Our family had a great time! Thank you!"
Shady Creek Cabin - Family Friendly Getaway Near Lake
Bear Historic Home
10.0 out of 10, Exceptional, (34)
"a perfect place to stay in the Niobara area. While most of our time was spent on the golf course, it was nice to see the sunrise over the river and unwind on the deck after the rounds at night. Highly recommend this property."
Bear Historic Home
Cozy Cabin get away - walking distant to beach
10.0 out of 10, Exceptional, (11)
"Cabin was very clean and very nice. Nice and close to the weigand state park area and CJ’s."
Cozy Cabin get away - walking distant to beach
Overlooks Lewis & Clark Lake/Missouri River Basin-3 Hours Northwest of Omaha
10.0 out of 10, Exceptional, (45)
"We have been coming here for a few years now once per summer, this host makes it feel special every time. They are very responsive to messages, as we wanted to be able to come in a day early they were able to accommodate us. The house is beautifully situated for the most amazing morning and all day views of the riverfront. Amazing wildlife, and special insiders hole in the wall must sees make it a treat to visit. We will be booking again soon, so long for now but not for long. Thank you for a...
Overlooks Lewis & Clark Lake/Missouri River Basin-3 Hours Northwest of Omaha
Secluded Lake View Log Cabin on 40 Acres
10.0 out of 10, Exceptional, (26)
"Such a beautiful home and location. Stunning views. Remote but close to town, Lewis and Clark, golf courses, etc. The owners were great and have the place very well stocked (best we’ve experienced in a rental property). All the outdoor games and activities you can think of. Top notch all around. We will be back!"
Secluded Lake View Log Cabin on 40 Acres
Pierson Ranch Overlook Near Lewis & Clark Lake
9.8 out of 10, Exceptional, (9)
"Place was as advertised, close to the lake and activities. Comfortable."
Pierson Ranch Overlook Near Lewis & Clark Lake
Haven by the Lake
10.0 out of 10, Exceptional, (11)
"Attended an archery tournament in Yankton and the house was very conveniently located. Very clean and easy to find. The kids especially enjoyed playing in the snow and sledding down the small hill in the back yard. The only issue we had was it did snow a lot while we were there so it was difficult to get in and out of the slopes driveway. Luckily we were in a 4x4 truck but we did have to use 4x4 to get up the driveway."
Haven by the Lake
Charming Lake House within Walking Distance from Lake
9.8 out of 10, Exceptional, (21)
"Our family loved the house and wish we could have stayed longer! Loved the games and deck to hang out on. Got some amazing sleep too! Husband was bummed to see no firepit. Definitely would recommend to anyone or start again!"
Charming Lake House within Walking Distance from Lake
Spacious, Scenic Wagner Haven w/ River Access
10.0 out of 10, Exceptional, (19)
"The house was over the top perfect for our family. It was spacious, everyone had their own space when they needed it. The kitchen/dining area was large enough for everyone to be in the kitchen at the same time helping cook. The property is near a river and the hike there and back was just what we needed for a workout. Golf cart was available to quick trips to the river. Peaceful and quiet surroundings. Already have reservations for next year"
Spacious, Scenic Wagner Haven w/ River Access
Lake property just a few blocks from public beach. Marina a mile away.
10.0 out of 10, Exceptional, (13)
"Great property, great host."
Lake property just a few blocks from public beach. Marina a mile away.
The Copper Lodge in Springfield
10.0 out of 10, Exceptional, (19)
"Extremely clean. Nice and quiet. All the amenities you could want."
The Copper Lodge in Springfield
Lakeview Cabin- minutes from beach!
10.0 out of 10, Exceptional, (13)
"The property is located right off of Lewis and Clark lake and near Yankton, South Dakota. The house is large, spacious and well equipped for families. The hosts are very accommodating and provided more in the house than we expected from kitchen appliances, accessories to utensils. Also the bedrooms are well appointed with beds, bunk beds and comforters. The bathrooms are spacious and well equipped with towels and soap/shampoo. This is a great property for families who want to experience this...
Lakeview Cabin- minutes from beach!
Leather&Spruce - Luxury Lake area fun funky home with amenities. Great for 2-18!
10.0 out of 10, Exceptional, (14)
"All was excellent!"
The price is $699
$959 total
includes taxes & fees
Jun 16 - Jun 17
Leather&Spruce - Luxury Lake area fun funky home with amenities. Great for 2-18!
Peaceful Farmhouse with hot tub
10.0 out of 10, Exceptional, (2)
"Very roomy plenty of space"
Peaceful Farmhouse with hot tub
Cottage on Verdigris Creek
9.8 out of 10, Exceptional, (6)
"This property is in a great location! It is clean and well stocked with the essentials! The check in and communication was great! I would stay there again."
Cottage on Verdigris Creek
Running Water Lodge with great amenities
10.0 out of 10, Exceptional, (1)
"We were very happy with the house. Lots of space, well equipped kitchen, great outdoor areas, and easy short drives to local attractions. The host was quick with responses, helpful, and friendly. We will definitely return."
Running Water Lodge with great amenities
Yankton home close to the lake
10.0 out of 10, Exceptional, (3)
"This property was a great fit for our family and the property owners were so easy to work with. If we rent again in Yankton, I will stay there again. Nice Neighborhood and it was, very quiet."
Yankton home close to the lake
Cozy Cabin along Apple tree road with access to boat ramp for boating & fishing
Cozy Cabin along Apple tree road with access to boat ramp for boating & fishing
Crofton Cabin w/ Tropical Hut & Water Views!
10.0 out of 10, Exceptional, (5)
"Cabin review. I’m writing this review a few months out from an absolutely amazing girls weekend spent at this cabin. I find myself thinking about it so often! First off I have to say the owners are very responsive and provide a ton of amenities. Their cabin is gorgeous and the views are done a disservice by the photos. We were a group of four middle aged women so the stairs didn’t pose a huge challenge but if you have more than one party who is physically limited it might be difficult as they...
Crofton Cabin w/ Tropical Hut & Water Views!
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See all available properties in Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other types of properties in Santee you may be interested in

Lewis and Clark Resort
2.5 star property
8.6 out of 10, Excellent, (164)
"Old fashioned "
Lewis and Clark Resort
Shady Creek Cabin - Family Friendly Getaway Near Lake
10.0 out of 10, Exceptional, (55)
"We loved the location and the property! Everything we needed was there. Communication with the owners was very good and they were very responsive to any questions . Our family had a great time! Thank you!"
Shady Creek Cabin - Family Friendly Getaway Near Lake
Overlooks Lewis & Clark Lake/Missouri River Basin-3 Hours Northwest of Omaha
10.0 out of 10, Exceptional, (45)
"We have been coming here for a few years now once per summer, this host makes it feel special every time. They are very responsive to messages, as we wanted to be able to come in a day early they were able to accommodate us. The house is beautifully situated for the most amazing morning and all day views of the riverfront. Amazing wildlife, and special insiders hole in the wall must sees make it a treat to visit. We will be booking again soon, so long for now but not for long. Thank you for a...
Overlooks Lewis & Clark Lake/Missouri River Basin-3 Hours Northwest of Omaha
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Everything you need to know about Santee vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santee vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santee vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Santee vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santee. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santee in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $699 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Santee rentals

At Expedia, we put the best Santee vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santee rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santee vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santee. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find a vacation rental in Santee?

Yes, we give you a choice of vacation rentals near top points of interest in Santee, or you can select a more remote option if you'd like a relaxing place to stay.

What are some of the best vacation rentals in Santee?

Retreat near the Lake and State Parks of Yankton: This vacation home rental outside of Santee offers a patio, a private yard, and air-conditioning to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a microwave, a coffee maker, and kitchenware.

What’s there to see and do in Santee?

While you're exploring the area, Lewis and Clark Lake and Niobrara State Park are a couple of picturesque spots to get outside and enjoy nature. Lewis and Clark Recreation Area and Lewis and Clark Lake State Recreation Area are a couple of places you'll find in the larger area.

What’s a vacation rental in Santee like?

A vacation rental is a private property you can book for a few weeks or just a few days in Santee. Vacation rentals offer amenities like WiFi and washers and dryers so you'll have all the comforts of home. If you're concerned about a clean environment, a vacation rental can offer a sense of privacy away from public hotel elevators and busy front desks while still allowing you the enjoyment of travel. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is a great choice for a family getaway.

Recent reviews of Santee properties
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