Find Resorts & Hotels with Spas in Panama Canal Zone

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Top Panama Canal Zone Resorts & Hotels with Spas

Radisson Colon 2,000 Hotel & Casino

4.0 star property
Barrio Sur
8.2 out of 10, Very Good, (812)
"Staff was great room was clean"
United States
Bridgett
$88 nightly
The price is $97
Dec 20 - Dec 21
Total with taxes and fees
Radisson Colon 2,000 Hotel & Casino

SAND DIAMOND HOTEL

3.0 star property
Colon
8.4 out of 10, Very Good, (210)
"Good place."
United States
Tinesha
$119 nightly
The price is $131
Dec 6 - Dec 7
Total with taxes and fees
SAND DIAMOND HOTEL

The Westin Playa Bonita Panama

5.0 star property
Veracruz
8.0 out of 10, Very Good, (1000)
"Clean rooms , friendly staff , had great experience "
United States
Saro
$166 nightly
The price is $183
Dec 16 - Dec 17
Total with taxes and fees
The Westin Playa Bonita Panama

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (635)
"As usual the stay was amazing in this hotel"
United States
Jose
$172 nightly
The price is $189
Dec 6 - Dec 7
Total with taxes and fees
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Dreams Playa Bonita Panama - All Inclusive

4.0 star property
Veracruz
7.6 out of 10, Good, (1002)
"Very good place "
United States
victor
$272 nightly
The price is $272
Dec 18 - Dec 19
Total with taxes and fees
Dreams Playa Bonita Panama - All Inclusive

Riande Aeropuerto Hotel & Casino

4.0 star property
Tocumen
8.6 out of 10, Excellent, (1856)
"I love the included shuttle and breakfast and how close it is to the airport"
United States
leon
$125 nightly
The price is $138
Dec 7 - Dec 8
Total with taxes and fees
Riande Aeropuerto Hotel & Casino

Sheraton Grand Panama

4.0 star property
San Francisco
8.6 out of 10, Excellent, (988)
"Great staff. Great restaurants and bakery. "
United States
Duncan Eric
$135 nightly
The price is $149
Dec 12 - Dec 13
Total with taxes and fees
Sheraton Grand Panama

Megapolis Hotel Panamá

4.5 star property
San Francisco
8.4 out of 10, Very Good, (1246)
"Its a very beautiful hotel with view and very good breakfast "
United States
Patrick
$114 nightly
The price is $125
Dec 20 - Dec 21
Total with taxes and fees
Megapolis Hotel Panamá

Hyatt Regency Panama City

4.5 star property
Bella Vista
10.0 out of 10, Exceptional, (115)
"Great hotel fair price"
United States
Santiago
$135 nightly
The price is $149
Dec 6 - Dec 7
Total with taxes and fees
Hyatt Regency Panama City

JW Marriott Panama

5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1001)
"Spotless, friendly and great food. Great pools a restaurants. "
Canada
David
$251 nightly
The price is $276
Jan 4 - Jan 5, 2026
Total with taxes and fees
JW Marriott Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Panama Canal Zone

Top Panama Canal Zone attractions for a relaxing vacation

In the Panama Canal Zone, travelers seeking hotels with spas will find a mix of relaxation and adventure. Start your journey at the Miraflores Locks, where you can witness massive ships navigate through the iconic canal; the visitor center offers an immersive experience that highlights the engineering marvel's history. For nature enthusiasts, the Soberanía National Park is a short drive away, featuring lush rainforests and diverse wildlife, perfect for hiking and birdwatching. After an active day, unwind at a luxury spa hotel in the vibrant Albrook area, where you can enjoy treatments that incorporate local ingredients like cacao and coffee. Don't miss the opportunity to explore the Panama Canal Railway, a scenic train ride that offers stunning views of the canal and surrounding landscapes. Finally, indulge in some retail therapy at the Albrook Mall, one of the largest shopping centers in Latin America, where you can find everything from local crafts to high-end brands. Staying in Albrook not only provides convenient access to these attractions but also ensures a pampered experience with attentive service at your hotel, making it a perfect base for your adventures.

Top Panama Canal Zone Hotel Reviews