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Resorts & Hotels with Spas in Panama from $121
Upfront pricingOur total price for your stay includes taxes and fees
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Our top choices for Panama hotels with a spa
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
Sortis Hotel, Spa & Casino, Autograph Collection by MarriottBella Vista
8.8 out of 10, Excellent, (1,007 reviews)
- Luxurious spa retreat in the heart of Panama with 10 treatment rooms and pampering Ayurvedic services for a complete wellness journey.
$150 nightly
The price is $165
Jul 15 - Jul 16
Total with taxes and fees
8.6 out of 10, Excellent, (2,632 reviews)
$110 nightly
The price is $121
Aug 11 - Aug 12
Total with taxes and fees
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama CityJuan Diaz
9.6 out of 10, Exceptional, (710 reviews)
- Discover tranquility at this luxury spa oasis with 5 treatment rooms and a garden retreat for the ultimate wellness escape.
$269 nightly
The price is $296
Jul 18 - Jul 19
Total with taxes and fees
$152 nightly
The price is $167
Aug 8 - Aug 9
Total with taxes and fees
9.4 out of 10, Exceptional, (1,006 reviews)
- Immerse in luxurious tranquility at this Art Deco hotel with 6 treatment rooms and an outdoor pool for a rejuvenating retreat.
$250 nightly
The price is $275
Jul 17 - Jul 18
Total with taxes and fees
Radisson Colon 2000 Hotel & Casino at Cruise Port & Duty Free Mall
Radisson Colon 2000 Hotel & Casino at Cruise Port & Duty Free MallBarrio Sur
8.2 out of 10, Very Good, (949 reviews)
- Rejuvenate at this waterfront hotel featuring couples spa treatments, an outdoor pool, and hot stone massages for a serene escape.
$116 nightly
The price is $128
Jul 28 - Jul 29
Total with taxes and fees
9.8 out of 10, Exceptional, (689 reviews)
- Indulge in a waterfront spa retreat with outdoor treatment areas and hot stone massages at this beautifully restored Colonial hotel.
$414 nightly
The price is $455
Jul 29 - Jul 30
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Panama Hotel Reviews
Waymore Hotel Spa & Casino
8/10 Good
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