Resorts & Hotels with Spas in Panama from $99
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Check availability on Panama Resorts & Hotels with Spas
Pick from 273 Panama Resorts & Hotels with Spas with updated room rates, reviews, and availability. Most hotels are fully refundable.

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
8.8 out of 10, Excellent, (983)
$159 nightly
The price is $175
Aug 24 - Aug 25
Total includes taxes and fees

Crowne Plaza Panama Airport by IHG
Crowne Plaza Panama Airport by IHG
8.4 out of 10, Very Good, (2187)
$114 nightly
The price is $125
Sep 8 - Sep 9
Total includes taxes and fees

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
9.6 out of 10, Exceptional, (598)
$212 nightly
The price is $234
Sep 7 - Sep 8
Total includes taxes and fees

Marriott Panama Hotel
Marriott Panama Hotel
9.0 out of 10, Wonderful, (1006)
$134 nightly
The price is $148
Sep 7 - Sep 8
Total includes taxes and fees

Bristol Panama, a Registry Collection Hotel
Bristol Panama, a Registry Collection Hotel
9.2 out of 10, Wonderful, (1003)
$200 nightly
The price is $220
Sep 19 - Sep 20
Total includes taxes and fees

W Panama
W Panama
8.8 out of 10, Excellent, (1006)
$199 nightly
The price is $219
Aug 30 - Aug 31
Total includes taxes and fees

Radisson Colon 2,000 Hotel & Casino
Radisson Colon 2,000 Hotel & Casino
8.0 out of 10, Very Good, (774)
$90 nightly
The price is $99
Aug 22 - Aug 23
Total includes taxes and fees

Sofitel Legend Casco Viejo, Panama City
Sofitel Legend Casco Viejo, Panama City
9.8 out of 10, Exceptional, (489)
$293 nightly
The price is $322
Sep 3 - Sep 4
Total includes taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Panama Hotel Reviews

Dreams Playa Bonita Panama - All Inclusive
10/10 Excellent