$208 Cheap American Airlines flights New Orleans (MSY) to Charlotte (CLT)

Grab affordable round-trip American Airlines flights from $139 from MSY to CLT by organizing your results from "Price (lowest to highest)" on Expedia. Or look for options from $208 for a one-way trip.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Look for affordable American Airlines flights from Louis Armstrong New Orleans Intl. Airport (MSY) to Charlotte-Douglas Intl. Airport (CLT) one to three months ahead of your day of departure. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. Regardless of fare type and itinerary, the best day of the week to book a domestic flight is usually Sunday and the most expensive is typically Monday. Passengers who book on a Sunday can save 6% on average compared to those who book on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Setting off from MSY at 7:10AM UTC-6, the earliest American Airlines flight to CLT lands at 10:14AM UTC-5. Traveling earlier in the day means you're less likely to encounter delays or cancellations.* Not an early riser? The last American Airlines flight from MSY to CLT departs at 6:51PM UTC-6 and touches down at 9:55PM UTC-5.*Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.