$1,012 Cheap Flights from Amsterdam (AMS) to São Tomé Island (TMS)

View $1,012 flight on Thu, Oct 9, 2025Opens in a new window

Popular airlines from Amsterdam Airport Schiphol (AMS) to São Tomé Island (TMS-São Tomé Intl.)

Cheap Flights from Amsterdam to São Tomé Island (AMS-TMS)

Prices were available within the past 7 days and start at $1,012 for one-way flights and $1,143 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

TAP Portugal
Sat, Nov 8 - Fri, Nov 14
AMS
Amsterdam
TMS
São Tomé Island
$1,143 Roundtrip, found 3 days ago
$1,143
Roundtrip
found 3 days ago
Select TAP Portugal flight, departing Sat, Nov 8 from Amsterdam to São Tomé Island, returning Fri, Nov 14, priced at $1,143 found 3 days ago
TAP Portugal
Sat, Nov 8 - Fri, Nov 14
AMS
Amsterdam
TMS
São Tomé Island
$1,185 Roundtrip, found 3 days ago
$1,185
Roundtrip
found 3 days ago
Select TAP Portugal flight, departing Sat, Nov 8 from Amsterdam to São Tomé Island, returning Fri, Nov 14, priced at $1,185 found 3 days ago
TAP Portugal
Sat, Nov 8 - Fri, Nov 14
AMS
Amsterdam
TMS
São Tomé Island
$1,215 Roundtrip, found 3 days ago
$1,215
Roundtrip
found 3 days ago
Select TAP Portugal flight, departing Sat, Nov 8 from Amsterdam to São Tomé Island, returning Fri, Nov 14, priced at $1,215 found 3 days ago
TAP Portugal
Sat, Nov 8 - Fri, Nov 14
AMS
Amsterdam
TMS
São Tomé Island
$1,233 Roundtrip, found 3 days ago
$1,233
Roundtrip
found 3 days ago
Select TAP Portugal flight, departing Sat, Nov 8 from Amsterdam to São Tomé Island, returning Fri, Nov 14, priced at $1,233 found 3 days ago
TAP Portugal
Sat, Nov 8 - Fri, Nov 14
AMS
Amsterdam
TMS
São Tomé Island
$1,257 Roundtrip, found 3 days ago
$1,257
Roundtrip
found 3 days ago
Select TAP Portugal flight, departing Sat, Nov 8 from Amsterdam to São Tomé Island, returning Fri, Nov 14, priced at $1,257 found 3 days ago
TAP Portugal
Sat, Nov 8 - Fri, Nov 14
AMS
Amsterdam
TMS
São Tomé Island
$1,287 Roundtrip, found 3 days ago
$1,287
Roundtrip
found 3 days ago
Select TAP Portugal flight, departing Sat, Nov 8 from Amsterdam to São Tomé Island, returning Fri, Nov 14, priced at $1,287 found 3 days ago
TAP Portugal
Sat, Nov 8 - Fri, Nov 14
AMS
Amsterdam
TMS
São Tomé Island
$1,305 Roundtrip, found 3 days ago
$1,305
Roundtrip
found 3 days ago
Select TAP Portugal flight, departing Sat, Nov 8 from Amsterdam to São Tomé Island, returning Fri, Nov 14, priced at $1,305 found 3 days ago
TAP Portugal
Sat, Nov 8 - Fri, Nov 14
AMS
Amsterdam
TMS
São Tomé Island
$1,311 Roundtrip, found 3 days ago
$1,311
Roundtrip
found 3 days ago
Select TAP Portugal flight, departing Sat, Nov 8 from Amsterdam to São Tomé Island, returning Fri, Nov 14, priced at $1,311 found 3 days ago
TAP Portugal
Sat, Nov 8 - Fri, Nov 14
AMS
Amsterdam
TMS
São Tomé Island
$1,353 Roundtrip, found 3 days ago
$1,353
Roundtrip
found 3 days ago
Select TAP Portugal flight, departing Sat, Nov 8 from Amsterdam to São Tomé Island, returning Fri, Nov 14, priced at $1,353 found 3 days ago
TAP Portugal
Sat, Nov 8 - Fri, Nov 14
AMS
Amsterdam
TMS
São Tomé Island
$1,359 Roundtrip, found 3 days ago
$1,359
Roundtrip
found 3 days ago
Select TAP Portugal flight, departing Sat, Nov 8 from Amsterdam to São Tomé Island, returning Fri, Nov 14, priced at $1,359 found 3 days ago
TAP Portugal
Sat, Nov 8 - Fri, Nov 14
AMS
Amsterdam
TMS
São Tomé Island
$1,400 Roundtrip, found 3 days ago
$1,400
Roundtrip
found 3 days ago
Select TAP Portugal flight, departing Sat, Nov 8 from Amsterdam to São Tomé Island, returning Fri, Nov 14, priced at $1,400 found 3 days ago
TAP Portugal
Sat, Nov 8 - Fri, Nov 14
AMS
Amsterdam
TMS
São Tomé Island
$1,407 Roundtrip, found 3 days ago
$1,407
Roundtrip
found 3 days ago
Select TAP Portugal flight, departing Sat, Nov 8 from Amsterdam to São Tomé Island, returning Fri, Nov 14, priced at $1,407 found 3 days ago
TAP Portugal
Sat, Nov 8 - Fri, Nov 14
AMS
Amsterdam
TMS
São Tomé Island
$1,448 Roundtrip, found 3 days ago
$1,448
Roundtrip
found 3 days ago
Select TAP Portugal flight, departing Sat, Nov 8 from Amsterdam to São Tomé Island, returning Fri, Nov 14, priced at $1,448 found 3 days ago
Flights from Amsterdam (AMS) to São Tomé Island (TMS)
Origin airport
Schiphol
Destination airport
São Tomé Intl.
Roundtrip price
$1,143
Distance
3589 mi

Amsterdam to São Tomé Island Flights

The cheapest times to fly from Amsterdam to São Tomé Island

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Amsterdam to São Tomé Island are during the month of November. You can find some of the cheapest flights from Amsterdam to São Tomé Island with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Amsterdam to São Tomé Island

Sunday is one of the best days to book for cheap flights from Amsterdam to São Tomé Island: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Amsterdam to São Tomé Island

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Amsterdam to São Tomé Island in 2025. You can also book with separate airlines for your outbound and return journeys, from $1,012 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Amsterdam to São Tomé Island flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Amsterdam to São Tomé Island airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Schiphol Airport (AMS) to Sao Tome Intl. Airport (TMS) cost?
Lock in a cheap one-way flight from $1,012 or cheap return flight from $1,143 from Schiphol Airport (AMS) to Sao Tome Intl. Airport (TMS) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Schiphol Airport (AMS) to Sao Tome Intl. Airport (TMS)?
November is the cheapest month to fly from AMS to TMS. Traveling during an off-peak travel window is often the key to finding a great deal.
What is the cheapest airline that flies from Schiphol Airport (AMS) to Sao Tome Intl. Airport (TMS)?
To find the cheapest airline flying from AMS to TMS, use Expedia's filter tool. Customize your search based on what's important to you, such as preferred carriers and flight duration. You can then sort your results by "Price (lowest to highest)" to see the cheapest flights first.
How many flights per day from Schiphol Airport (AMS) to Sao Tome Intl. Airport (TMS)?
You'll need to catch a flight with a layover if you're traveling from Schiphol Airport (AMS) to Sao Tome Intl. Airport (TMS). Direct flights don't operate daily on this route. However, simply filter your search to include one or two stops to discover the best option for your trip.
What day of the week has the most flights from AMS to TMS?
You'll typically find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Schiphol Airport (AMS) to Sao Tome Intl. Airport (TMS)?
To land at Sao Tome Intl. Airport (TMS) without delays, pick a flight that leaves from Schiphol Airport (AMS) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Schiphol Airport (AMS) to Sao Tome Intl. Airport (TMS) last-minute?
Last-minute bookings from AMS to TMS are usually more expensive. For the cheapest rates, start looking for flights well in advance. That being said, if you can play around with your travel dates, you may land a cheap ticket right before you leave.
Is it cheaper to book an AMS to TMS flight and hotel package?
Booking an AMS to TMS flight and hotel package is typically cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels in one place. Choose from our wide range of accommodations and then add car rentals, flights and activities to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Schiphol Airport (AMS) to Sao Tome Intl. Airport (TMS)?
It's generally possible to reschedule or cancel your AMS to TMS flight. However, if the booking was made more than 24 hours ago, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are possible and if any costs are involved. You'll also find more details on our Customer Service portal.

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*Available to One Key members.