Cheap Flights from Florence (FLO) to Destin (DSI)

Popular airlines from Florence, SC (FLO-Florence Regional) to Destin-Fort Walton Beach Airport (DSI)

Alternative airports near Destin

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Northwest Florida Regional VPS. Cheapest option available. Average driving time to city center is 29 minutes. Flights from $465
VPS
Northwest Florida Regional
Cheapest
Average driving time to city center29 min
Flights from $465

Frequently asked questions

How much does a flight from Florence Regional Airport (FLO) to Destin-Fort Walton Beach Airport (DSI) cost?
Secure a cheap one-way flight or cheap return flight from Florence Regional Airport (FLO) to Destin-Fort Walton Beach Airport (DSI) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Florence Regional Airport (FLO) to Destin-Fort Walton Beach Airport (DSI)?
Planning your trip for is a great way to save, as it's the cheapest month for flights between FLO and DSI. You'll typically find the lowest prices during off-peak months.
What is the cheapest airline that flies from Florence Regional Airport (FLO) to Destin-Fort Walton Beach Airport (DSI)?
Expedia's filter tool lets you easily compare different airlines, travel time and fares all in one place. Tailor the search to your trip, then sort by "Price (lowest to highest)" to find out which carrier offers the cheapest FLO to DSI flight.
How many flights per day from Florence Regional Airport (FLO) to Destin-Fort Walton Beach Airport (DSI)?
You'll have to book a flight with a layover if you're traveling from Florence Regional Airport (FLO) to Destin-Fort Walton Beach Airport (DSI). There are no daily direct flights on this route. However, just filter your search to include one or more stops to find the best option for your trip.
What day of the week has the most flights from FLO to DSI?
Friday is usually the busiest day for flights, while Tuesday tends to be the quietest.* Remember that flight schedules can vary based on a number of factors, including the carrier and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Florence Regional Airport (FLO) to Destin-Fort Walton Beach Airport (DSI)?
To land at Destin-Fort Walton Beach Airport (DSI) on schedule, opt for a flight that leaves Florence Regional Airport (FLO) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Florence Regional Airport (FLO) to Destin-Fort Walton Beach Airport (DSI) last-minute?
Holding off until right before your break to book your flight from FLO to DSI generally means paying more. Although you may find some last-minute discounts, there's no guarantee. Be flexible with your itinerary to maximize your chances of snagging a bargain.
Is it cheaper to book a FLO to DSI flight and hotel package?
Securing a FLO to DSI flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your trip in one place. Choose from our extensive range of stays and then add flights, car rentals and activities to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Florence Regional Airport (FLO) to Destin-Fort Walton Beach Airport (DSI)?
It's generally possible to cancel or reschedule your FLO to DSI flight. However, if the booking was made more than 24 hours ago, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find further details on our Customer Service portal.

Travel information

Origin airport
Florence Regional
Destination airport
Destin-Fort Walton Beach
Distance
472 mi

Book with confidence

Florence to Destin Flights

The cheapest times to fly from Florence to Destin

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Florence to Destin are during the month of . You can find some of the cheapest flights from Florence to Destin with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Florence to Destin

Sunday is one of the best days to book for cheap flights from Florence to Destin: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Florence to Destin

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Florence to Destin in 2025. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Florence to Destin flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Florence to Destin airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Florence to Destin Flights

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*Available to One Key members.