$297 Cheap Flights from Manaus (MAO) to Santo Domingo (SDQ)

View $297 flight on Sat, Oct 18, 2025Opens in a new window

Popular airlines from Manaus (MAO-Eduardo Gomes Intl.) to Las Americas Intl. Airport (SDQ)

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Cheap Flights from Manaus to Santo Domingo (MAO-SDQ)

Prices were available within the past 7 days and start at $297 for one-way flights and $813 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Fri, Dec 19 - Sat, Jan 10
MAO
Manaus
SDQ
Santo Domingo
$813 Roundtrip, found 13 hours ago
$813
Roundtrip
found 13 hours ago
Select Copa flight, departing Fri, Dec 19 from Manaus to Santo Domingo, returning Sat, Jan 10, priced at $813 found 13 hours ago
Copa
Fri, Dec 19 - Sat, Jan 10
MAO
Manaus
SDQ
Santo Domingo
$862 Roundtrip, found 13 hours ago
$862
Roundtrip
found 13 hours ago
Select Copa flight, departing Fri, Dec 19 from Manaus to Santo Domingo, returning Sat, Jan 10, priced at $862 found 13 hours ago
Copa
Fri, Dec 19 - Sat, Jan 10
MAO
Manaus
SDQ
Santo Domingo
$878 Roundtrip, found 13 hours ago
$878
Roundtrip
found 13 hours ago
Select Copa flight, departing Fri, Dec 19 from Manaus to Santo Domingo, returning Sat, Jan 10, priced at $878 found 13 hours ago
Copa
Fri, Dec 19 - Sat, Jan 10
MAO
Manaus
SDQ
Santo Domingo
$880 Roundtrip, found 13 hours ago
$880
Roundtrip
found 13 hours ago
Select Copa flight, departing Fri, Dec 19 from Manaus to Santo Domingo, returning Sat, Jan 10, priced at $880 found 13 hours ago
Copa
Fri, Dec 19 - Sat, Jan 10
MAO
Manaus
SDQ
Santo Domingo
$927 Roundtrip, found 13 hours ago
$927
Roundtrip
found 13 hours ago
Select Copa flight, departing Fri, Dec 19 from Manaus to Santo Domingo, returning Sat, Jan 10, priced at $927 found 13 hours ago
GOL Linhas Aereas S.A.
Fri, Dec 19 - Sat, Jan 10
MAO
Manaus
SDQ
Santo Domingo
$957 Roundtrip, found 13 hours ago
$957
Roundtrip
found 13 hours ago
Select GOL Linhas Aereas S.A. flight, departing Fri, Dec 19 from Manaus to Santo Domingo, returning Sat, Jan 10, priced at $957 found 13 hours ago
Copa
Fri, Dec 19 - Sat, Jan 10
MAO
Manaus
SDQ
Santo Domingo
$976 Roundtrip, found 13 hours ago
$976
Roundtrip
found 13 hours ago
Select Copa flight, departing Fri, Dec 19 from Manaus to Santo Domingo, returning Sat, Jan 10, priced at $976 found 13 hours ago
Copa
Fri, Dec 19 - Sat, Jan 10
MAO
Manaus
SDQ
Santo Domingo
$1,008 Roundtrip, found 13 hours ago
$1,008
Roundtrip
found 13 hours ago
Select Copa flight, departing Fri, Dec 19 from Manaus to Santo Domingo, returning Sat, Jan 10, priced at $1,008 found 13 hours ago
GOL Linhas Aereas S.A.
Fri, Dec 19 - Sat, Jan 10
MAO
Manaus
SDQ
Santo Domingo
$1,063 Roundtrip, found 13 hours ago
$1,063
Roundtrip
found 13 hours ago
Select GOL Linhas Aereas S.A. flight, departing Fri, Dec 19 from Manaus to Santo Domingo, returning Sat, Jan 10, priced at $1,063 found 13 hours ago
Delta
Fri, Dec 19 - Sat, Jan 10
MAO
Manaus
SDQ
Santo Domingo
$1,254 Roundtrip, found 13 hours ago
$1,254
Roundtrip
found 13 hours ago
Select Delta flight, departing Fri, Dec 19 from Manaus to Santo Domingo, returning Sat, Jan 10, priced at $1,254 found 13 hours ago
Flights from Manaus (MAO) to Santo Domingo (SDQ)
Origin airport
Eduardo Gomes Intl.
Destination airport
Las Americas Intl.
Airlines serving
Copa, Delta
Roundtrip price
$813
Distance
1621 mi

Manaus to Santo Domingo Flights

The cheapest times to fly from Manaus to Santo Domingo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Manaus to Santo Domingo are during the month of December. You can find some of the cheapest flights from Manaus to Santo Domingo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Manaus to Santo Domingo

Sunday is one of the best days to book for cheap flights from Manaus to Santo Domingo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Manaus to Santo Domingo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Manaus to Santo Domingo in 2025. You can also book with separate airlines for your outbound and return journeys, from $297 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Manaus to Santo Domingo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Manaus to Santo Domingo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Eduardo Gomes Intl. Airport (MAO) to Las Americas Intl. Airport (SDQ) cost?
Lock in a cheap one-way flight from $297 or cheap return flight from $813 from Eduardo Gomes Intl. Airport (MAO) to Las Americas Intl. Airport (SDQ) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Eduardo Gomes Intl. Airport (MAO) to Las Americas Intl. Airport (SDQ)?
December is the most affordable month to fly from MAO to SDQ. Planning your trip for the off-season is often the key to better flight prices.
What is the cheapest airline that flies from Eduardo Gomes Intl. Airport (MAO) to Las Americas Intl. Airport (SDQ)?
Expedia's filter tool lets you easily compare airlines, flight times and fares all in one place. Customize the search to your preferences, then sort by "Price (lowest to highest)" to find the carrier with the cheapest MAO to SDQ flight.
How many flights per day from Eduardo Gomes Intl. Airport (MAO) to Las Americas Intl. Airport (SDQ)?
Direct flights from Eduardo Gomes Intl. Airport (MAO) to Las Americas Intl. Airport (SDQ) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your dates and select either "1 Stop" or "2+ Stops."
What day of the week has the most flights from MAO to SDQ?
Friday is generally the busiest day for flights, while Tuesday is often the quietest.* Remember that flight schedules can change based on a number of factors, such as the season and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Eduardo Gomes Intl. Airport (MAO) to Las Americas Intl. Airport (SDQ)?
To arrive at Las Americas Intl. Airport (SDQ) without delays, choose a flight that leaves Eduardo Gomes Intl. Airport (MAO) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Eduardo Gomes Intl. Airport (MAO) to Las Americas Intl. Airport (SDQ) last-minute?
Last-minute fares from MAO to SDQ are usually more expensive. For the lowest prices, start searching for flights early. That being said, if you're flexible with your travel plans, it's possible to find a cheap fare right before your journey.
Is it cheaper to book a MAO to SDQ flight and hotel package?
Opting for a MAO to SDQ flight and hotel package is typically cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels in one place. Choose from our wide range of accommodations and then add activities, flights and car rentals to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Eduardo Gomes Intl. Airport (MAO) to Las Americas Intl. Airport (SDQ)?
You can usually reschedule or cancel your MAO to SDQ flight. However, if the booking was made more than 24 hours ago, additional fees may apply. Check your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find more information on our Customer Service portal.

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*Available to One Key members.