$549 Cheap Flights from Mexico City (MEX) to Johannesburg (JNB)

View $549 flight on Thu, Dec 4, 2025Opens in a new window

Popular airlines from Benito Juarez International Airport (MEX) to O.R. Tambo Intl. Airport (JNB)

Cheap Flights from Mexico City to Johannesburg (MEX-JNB)

Prices were available within the past 7 days and start at $549 for one-way flights and $1,056 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Fri, May 1 - Sat, May 9
MEX
Mexico City
JNB
Johannesburg
$1,056 Roundtrip, found 2 days ago
$1,056
Roundtrip
found 2 days ago
Select United flight, departing Fri, May 1 from Mexico City to Johannesburg, returning Sat, May 9, priced at $1,056 found 2 days ago
United
Fri, May 1 - Mon, May 18
MEX
Mexico City
JNB
Johannesburg
$1,108 Roundtrip, found 4 days ago
$1,108
Roundtrip
found 4 days ago
Select United flight, departing Fri, May 1 from Mexico City to Johannesburg, returning Mon, May 18, priced at $1,108 found 4 days ago
United
Tue, Apr 28 - Mon, May 18
MEX
Mexico City
JNB
Johannesburg
$1,112 Roundtrip, found 4 days ago
$1,112
Roundtrip
found 4 days ago
Select United flight, departing Tue, Apr 28 from Mexico City to Johannesburg, returning Mon, May 18, priced at $1,112 found 4 days ago
United
Sun, Nov 23 - Tue, Dec 2
MEX
Mexico City
JNB
Johannesburg
$1,194 Roundtrip, found 6 days ago
$1,194
Roundtrip
found 6 days ago
Select United flight, departing Sun, Nov 23 from Mexico City to Johannesburg, returning Tue, Dec 2, priced at $1,194 found 6 days ago
United
Fri, May 1 - Fri, May 8
MEX
Mexico City
JNB
Johannesburg
$1,197 Roundtrip, found 2 days ago
$1,197
Roundtrip
found 2 days ago
Select United flight, departing Fri, May 1 from Mexico City to Johannesburg, returning Fri, May 8, priced at $1,197 found 2 days ago
United
Fri, May 1 - Tue, May 12
MEX
Mexico City
JNB
Johannesburg
$1,205 Roundtrip, found 2 days ago
$1,205
Roundtrip
found 2 days ago
Select United flight, departing Fri, May 1 from Mexico City to Johannesburg, returning Tue, May 12, priced at $1,205 found 2 days ago
Virgin Atlantic
Mon, Feb 2 - Mon, Feb 16
MEX
Mexico City
JNB
Johannesburg
$1,311 Roundtrip, found 16 hours ago
$1,311
Roundtrip
found 16 hours ago
Select Virgin Atlantic flight, departing Mon, Feb 2 from Mexico City to Johannesburg, returning Mon, Feb 16, priced at $1,311 found 16 hours ago
Delta
Sat, May 2 - Sun, May 10
MEX
Mexico City
JNB
Johannesburg
$1,358 Roundtrip, found 2 days ago
$1,358
Roundtrip
found 2 days ago
Select Delta flight, departing Sat, May 2 from Mexico City to Johannesburg, returning Sun, May 10, priced at $1,358 found 2 days ago
Air Canada
Mon, May 4 - Sun, May 10
MEX
Mexico City
JNB
Johannesburg
$1,363 Roundtrip, found 2 days ago
$1,363
Roundtrip
found 2 days ago
Select Air Canada flight, departing Mon, May 4 from Mexico City to Johannesburg, returning Sun, May 10, priced at $1,363 found 2 days ago
KLM
Sat, Mar 21 - Sun, Mar 29
MEX
Mexico City
JNB
Johannesburg
$1,420 Roundtrip, found 1 day ago
$1,420
Roundtrip
found 1 day ago
Select KLM flight, departing Sat, Mar 21 from Mexico City to Johannesburg, returning Sun, Mar 29, priced at $1,420 found 1 day ago

Alternative airports near Johannesburg

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to O.R. Tambo Intl. JNB. Cheapest option available. Average driving time to city center is 17 minutes. Flights from $1,298
JNB
O.R. Tambo Intl.
Cheapest
Average driving time to city center17 min
Flights from $1,298

Frequently asked questions

How much does a flight from Mexico City Intl. Airport (MEX) to O.R. Tambo Intl. Airport (JNB) cost?
Lock in a cheap one-way flight from $549 or cheap return flight from $1,056 from Mexico City Intl. Airport (MEX) to O.R. Tambo Intl. Airport (JNB) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Mexico City Intl. Airport (MEX) to O.R. Tambo Intl. Airport (JNB)?
Planning your getaway for May is a great way to save, as it's the cheapest month for flights between MEX and JNB. You'll typically find the lowest fares during off-peak months.
What is the cheapest airline that flies from Mexico City Intl. Airport (MEX) to O.R. Tambo Intl. Airport (JNB)?
To find the cheapest airline that'll fly you from MEX to JNB, use Expedia's filter tool. Tailor your search based on your travel style, such as preferred carriers and seat class. You can then sort your results by "Price (lowest to highest)" to see the cheapest fares upfront.
How many flights per day from Mexico City Intl. Airport (MEX) to O.R. Tambo Intl. Airport (JNB)?
Nonstop flights from Mexico City Intl. Airport (MEX) to O.R. Tambo Intl. Airport (JNB) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filters. Enter your travel dates and pick either "1 Stop" or "2+ Stops."
What day of the week has the most flights from MEX to JNB?
Friday is generally the busiest day for flights, while Tuesday tends to be the quietest.* Just remember that flight schedules can change depending on a range of factors, such as the time of year and carrier.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Mexico City Intl. Airport (MEX) to O.R. Tambo Intl. Airport (JNB)?
To avoid possible delays on the Mexico City Intl. Airport (MEX) to O.R. Tambo Intl. Airport (JNB) route, travel before 3 PM. Departures after this time are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Mexico City Intl. Airport (MEX) to O.R. Tambo Intl. Airport (JNB) last-minute?
Last-minute fares from MEX to JNB are generally more expensive. To secure the best rates, start looking for flights as soon as possible. That said, if you're flexible with your travel dates, you may find a cheap ticket right before your trip.
Is it cheaper to book a MEX to JNB flight and hotel package?
Compared with arranging flights and hotels separately, booking a MEX to JNB flight and hotel package with Expedia could lead to significant savings. Better yet, having everything in one easy place will take the hassle out of planning your trip. Just secure your flights and select from our extensive range of stays, then personalize your trip with extras like activities and car rentals.
Can I cancel or change the date of my flight from Mexico City Intl. Airport (MEX) to O.R. Tambo Intl. Airport (JNB)?
In most cases, you can cancel or modify your MEX to JNB flight. However, there may be additional fees, especially if your booking was made over 24 hours ago. Check your itinerary for the airline's fees and guidelines on flight changes, or if you'd like further information, visit our Customer Service portal.

Travel information

Origin airport
Mexico City Intl.
Destination airport
O.R. Tambo Intl.
Airlines serving
Air Canada, Air France, British Airways, Delta, Emirates, KLM, LATAM Airlines Group, Lufthansa, Qatar Airways, Swiss International Air Lines, Turkish Airlines, United, Virgin Atlantic
Roundtrip price
$1,055
Distance
9070 mi

Book with confidence

Mexico City to Johannesburg Flights

The cheapest times to fly from Mexico City to Johannesburg

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Mexico City to Johannesburg are during the month of May. You can find some of the cheapest flights from Mexico City to Johannesburg with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Mexico City to Johannesburg

Sunday is one of the best days to book for cheap flights from Mexico City to Johannesburg: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Mexico City to Johannesburg

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Mexico City to Johannesburg in 2025. You can also book with separate airlines for your outbound and return journeys, from $549 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Mexico City to Johannesburg flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Mexico City to Johannesburg airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Mexico City to Johannesburg Flights

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*Available to One Key members.