Cheap Flights from Mexico City (MEX) to São Tomé Island (TMS)

Popular airlines from Benito Juarez International Airport (MEX) to São Tomé Island (TMS-São Tomé Intl.)

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Frequently asked questions

How much does a flight from Mexico City Intl. Airport (MEX) to Sao Tome Intl. Airport (TMS) cost?
Get a cheap one-way flight or cheap return flight from Mexico City Intl. Airport (MEX) to Sao Tome Intl. Airport (TMS) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Mexico City Intl. Airport (MEX) to Sao Tome Intl. Airport (TMS)?
Flying in may help you find better deals, as it's the cheapest month for flights between MEX and TMS. You'll often find the lowest prices during the off-season.
What is the cheapest airline that flies from Mexico City Intl. Airport (MEX) to Sao Tome Intl. Airport (TMS)?
Use the filters on Expedia to compare different airlines and find the most affordable carrier that'll fly you from MEX to TMS. Then, sort your results by "Price (lowest to highest)" to score the best deal available.
How many flights per day from Mexico City Intl. Airport (MEX) to Sao Tome Intl. Airport (TMS)?
You'll need to catch a flight with a layover if you're traveling from Mexico City Intl. Airport (MEX) to Sao Tome Intl. Airport (TMS). Direct flights don't operate daily on this route. However, just filter your search to include one or more stops to discover an option that works for you.
What day of the week has the most flights from MEX to TMS?
Friday is typically the busiest day for flights, while Tuesday is often the quietest.* Remember that flight schedules can change depending on a range of factors, including the time of year and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Mexico City Intl. Airport (MEX) to Sao Tome Intl. Airport (TMS)?
Book a flight from Mexico City Intl. Airport (MEX) to Sao Tome Intl. Airport (TMS) that leaves before 3 PM to reduce the risk of cancellations. Departures after this time are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Mexico City Intl. Airport (MEX) to Sao Tome Intl. Airport (TMS) last-minute?
Holding off until right before your break to book a ticket from MEX to TMS generally means paying more. While you may find some last-minute deals, there's no guarantee. Keep your travel schedule open for a better chance of landing a bargain.
Is it cheaper to book a MEX to TMS flight and hotel package?
Securing a MEX to TMS flight and hotel package is typically cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your trip all in one place. Select from our wide range of accommodations and then add activities, car rentals and flights to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Mexico City Intl. Airport (MEX) to Sao Tome Intl. Airport (TMS)?
It's usually possible to cancel or reschedule your MEX to TMS flight. However, if the booking was made more than 24 hours ago, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and if any costs are involved. You'll also find further details on our Customer Service portal.

Travel information

Travel information

Origin airport
Mexico City Intl.
Destination airport
São Tomé Intl.
Distance
7236 mi

Book with confidence

Book with confidence

Mexico City to São Tomé Island Flights

The cheapest times to fly from Mexico City to São Tomé Island

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Mexico City to São Tomé Island are during the month of . You can find some of the cheapest flights from Mexico City to São Tomé Island with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Mexico City to São Tomé Island

Sunday is one of the best days to book for cheap flights from Mexico City to São Tomé Island: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Mexico City to São Tomé Island

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Mexico City to São Tomé Island in 2025. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Mexico City to São Tomé Island flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Mexico City to São Tomé Island airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Mexico City to São Tomé Island Flights
*Available to One Key members.