$106 Cheap Flights from Mobile (MOB) to Chicago (ORD)

View $106 flight on Wed, Oct 29, 2025Opens in a new window

Popular airlines from Mobile Regional Airport (MOB) to Chicago O'Hare Intl. Airport (ORD)

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Cheap Flights from Mobile to Chicago (MOB-ORD)

Prices were available within the past 7 days and start at $106 for one-way flights and $211 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Tue, Nov 25 - Tue, Dec 2
MOB
Mobile
ORD
Chicago
$211 Roundtrip, found 1 day ago
$211
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Nov 25 from Mobile to Chicago, returning Tue, Dec 2, priced at $211 found 1 day ago
American Airlines
Sat, Oct 18 - Wed, Oct 22
MOB
Mobile
ORD
Chicago
$216 Roundtrip, found 2 days ago
$216
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, Oct 18 from Mobile to Chicago, returning Wed, Oct 22, priced at $216 found 2 days ago
Delta
Wed, Dec 17 - Thu, Dec 25
MOB
Mobile
ORD
Chicago
$230 Roundtrip, found 6 hours ago
$230
Roundtrip
found 6 hours ago
Select Delta flight, departing Wed, Dec 17 from Mobile to Chicago, returning Thu, Dec 25, priced at $230 found 6 hours ago
Delta
Tue, Aug 26 - Tue, Sep 16
MOB
Mobile
ORD
Chicago
$235 Roundtrip, found 2 days ago
$235
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, Aug 26 from Mobile to Chicago, returning Tue, Sep 16, priced at $235 found 2 days ago
American Airlines
Sat, Sep 6 - Thu, Sep 11
MOB
Mobile
ORD
Chicago
$235 Roundtrip, found 3 days ago
$235
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Sep 6 from Mobile to Chicago, returning Thu, Sep 11, priced at $235 found 3 days ago
American Airlines
Sat, Sep 6 - Thu, Sep 11
MOB
Mobile
ORD
Chicago
$240 Roundtrip, found 3 days ago
$240
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Sep 6 from Mobile to Chicago, returning Thu, Sep 11, priced at $240 found 3 days ago
American Airlines
Sat, Oct 18 - Wed, Oct 22
MOB
Mobile
ORD
Chicago
$243 Roundtrip, found 2 days ago
$243
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, Oct 18 from Mobile to Chicago, returning Wed, Oct 22, priced at $243 found 2 days ago
Delta
Wed, Dec 17 - Wed, Dec 31
MOB
Mobile
ORD
Chicago
$245 Roundtrip, found 6 hours ago
$245
Roundtrip
found 6 hours ago
Select Delta flight, departing Wed, Dec 17 from Mobile to Chicago, returning Wed, Dec 31, priced at $245 found 6 hours ago
American Airlines
Sat, Oct 18 - Wed, Oct 22
MOB
Mobile
ORD
Chicago
$250 Roundtrip, found 2 days ago
$250
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, Oct 18 from Mobile to Chicago, returning Wed, Oct 22, priced at $250 found 2 days ago
United
Mon, Sep 1 - Mon, Sep 22
MOB
Mobile
ORD
Chicago
$456 Roundtrip, found 3 days ago
$456
Roundtrip
found 3 days ago
Select United flight, departing Mon, Sep 1 from Mobile to Chicago, returning Mon, Sep 22, priced at $456 found 3 days ago

Find the cheapest month to fly from Mobile (MOB) to Chicago (ORD)

October is typically the cheapest month to fly

From $203 - $473 per traveler.

Graph displaying average flight prices per month

Alternative airports near Chicago

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Midway Intl. MDW. Closest option available. Average driving time to city center is 16 minutes. Flights from $255
MDW
Midway Intl.
Closest
Average driving time to city center16 min
Flights from $255
Flights from Mobile (MOB) to Chicago (ORD)
Origin airport
Mobile Regional
Destination airport
O'Hare Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$210
Distance
780 mi

Mobile to Chicago Flights

The cheapest times to fly from Mobile to Chicago

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Mobile to Chicago are during the month of November. You can find some of the cheapest flights from Mobile to Chicago with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Mobile to Chicago

Sunday is one of the best days to book for cheap flights from Mobile to Chicago: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Mobile to Chicago

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Mobile to Chicago in 2025. You can also book with separate airlines for your outbound and return journeys, from $106 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Mobile to Chicago flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Mobile to Chicago airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Mobile Regional Airport (MOB) to O'Hare Intl. Airport (ORD) cost?
Grab a cheap one-way flight from $106 or cheap return flight from $211 from Mobile Regional Airport (MOB) to O'Hare Intl. Airport (ORD) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Mobile Regional Airport (MOB) to O'Hare Intl. Airport (ORD)?
November is the most affordable month to fly from MOB to ORD. Avoiding peak travel times is often the key to finding better deals on flights.
Which airlines fly direct from Mobile Regional Airport (MOB) to O'Hare Intl. Airport (ORD)?
There are no direct routes from Mobile, AL (MOB-Mobile Regional) to O'Hare Intl. Airport (ORD). However, there are other airports that have nonstop flights. Board your plane at Gulfport - Biloxi Intl. Airport (GPT) and head straight to Chicago without layovers.
What is the cheapest airline that flies from Mobile Regional Airport (MOB) to O'Hare Intl. Airport (ORD)?
To find the cheapest airline flying from MOB to ORD, use Expedia's filter tool. Customize your search based on what's important to you, such as preferred carriers and flight duration. You can then sort your results by "Price (lowest to highest)" to list the most affordable options first.
How many flights per day from Mobile Regional Airport (MOB) to O'Hare Intl. Airport (ORD)?
You'll have to catch a flight with a layover if you're traveling from Mobile Regional Airport (MOB) to O'Hare Intl. Airport (ORD). There are no daily direct flights on this route. However, simply filter your search to include one or two stops to discover an option that works for you.
What day of the week has the most flights from MOB to ORD?
Friday is typically the busiest day for flights, while Tuesday tends to be the quietest.* Remember that flight schedules can vary based on a range of factors, including the carrier and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Mobile Regional Airport (MOB) to O'Hare Intl. Airport (ORD)?
Choose a flight from Mobile Regional Airport (MOB) to O'Hare Intl. Airport (ORD) that takes off before 3 PM to reduce the risk of delays and cancellations. Later departures have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Mobile Regional Airport (MOB) to O'Hare Intl. Airport (ORD) last-minute?
Waiting until just before your departure to book your flight from MOB to ORD often results in higher prices. While you may find some last-minute deals, there's no guarantee. Keep your travel schedule open for the best chance of getting a bargain.
Is it cheaper to book a MOB to ORD flight and hotel package?
Compared with arranging flights and hotels separately, booking a MOB to ORD flight and hotel package with Expedia could lead to significant savings. Better still, having everything in one convenient place will take the hassle out of planning your trip. Simply pick your flights and select from our wide range of hotels, then tailor your trip with extras like tours, activities and car rentals.
Can I cancel or change the date of my flight from Mobile Regional Airport (MOB) to O'Hare Intl. Airport (ORD)?
In most cases, you can cancel or modify your MOB to ORD flight. However, additional fees may apply, especially if you booked over 24 hours ago. Check your itinerary for the airline's fees and rules on flight changes, or if you need more details, visit our Customer Service portal.

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*Available to One Key members.