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$154 Cheap Flights from Mobile (MOB) to Chicago (ORD)

View $154 flight on Sun, Sep 6, 2026Opens in a new window

Popular airlines from Mobile Regional Airport (MOB) to Chicago O'Hare Intl. Airport (ORD)

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Cheap Flights from Mobile to Chicago (MOB-ORD)

Prices were available within the past 7 days and start at $154 for one-way flights and $313 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Sep 23 - Sun, Sep 27
MOB
Mobile
ORD
Chicago
$313 Roundtrip, found 1 day ago
$313
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Sep 23 from Mobile to Chicago, returning Sun, Sep 27, priced at $313 found 1 day ago
Delta
Wed, Aug 26 - Sat, Aug 29
MOB
Mobile
ORD
Chicago
$317 Roundtrip, found 1 hour ago
$317
Roundtrip
found 1 hour ago
Select Delta flight, departing Wed, Aug 26 from Mobile to Chicago, returning Sat, Aug 29, priced at $317 found 1 hour ago
Delta
Fri, Sep 4 - Tue, Sep 8
MOB
Mobile
ORD
Chicago
$318 Roundtrip, found 2 hours ago
$318
Roundtrip
found 2 hours ago
Select Delta flight, departing Fri, Sep 4 from Mobile to Chicago, returning Tue, Sep 8, priced at $318 found 2 hours ago
Delta
Fri, Sep 18 - Sun, Sep 20
MOB
Mobile
ORD
Chicago
$319 Roundtrip, just found
$319
Roundtrip
just found
Select Delta flight, departing Fri, Sep 18 from Mobile to Chicago, returning Sun, Sep 20, priced at $319 just found
Delta
Tue, Nov 17 - Sat, Nov 21
MOB
Mobile
ORD
Chicago
$327 Roundtrip, found 9 hours ago
$327
Roundtrip
found 9 hours ago
Select Delta flight, departing Tue, Nov 17 from Mobile to Chicago, returning Sat, Nov 21, priced at $327 found 9 hours ago
Delta
Wed, Oct 21 - Mon, Oct 26
MOB
Mobile
ORD
Chicago
$328 Roundtrip, found 1 day ago
$328
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Oct 21 from Mobile to Chicago, returning Mon, Oct 26, priced at $328 found 1 day ago
Delta
Thu, Oct 15 - Sun, Oct 18
MOB
Mobile
ORD
Chicago
$329 Roundtrip, found 15 hours ago
$329
Roundtrip
found 15 hours ago
Select Delta flight, departing Thu, Oct 15 from Mobile to Chicago, returning Sun, Oct 18, priced at $329 found 15 hours ago
American Airlines
Fri, Aug 7 - Fri, Aug 14
MOB
Mobile
ORD
Chicago
$334 Roundtrip, found 6 hours ago
$334
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Fri, Aug 7 from Mobile to Chicago, returning Fri, Aug 14, priced at $334 found 6 hours ago
American Airlines
Sat, Aug 8 - Mon, Aug 10
MOB
Mobile
ORD
Chicago
$339 Roundtrip, found 3 days ago
$339
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Aug 8 from Mobile to Chicago, returning Mon, Aug 10, priced at $339 found 3 days ago
United
Wed, Sep 9 - Fri, Sep 11
MOB
Mobile
ORD
Chicago
$558 Roundtrip, found 6 days ago
$558
Roundtrip
found 6 days ago
Select United flight, departing Wed, Sep 9 from Mobile to Chicago, returning Fri, Sep 11, priced at $558 found 6 days ago

Alternative airports near Chicago

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Midway Intl. MDW. Closest option available. Average driving time to city center is 16 minutes. Flights from $349
MDW
Midway Intl.
Closest
Average driving time to city center16 min
Flights from $349

Find the cheapest month to fly from Mobile (MOB) to Chicago (ORD)

April is typically the cheapest month to fly

From $210 - $412 per traveler.

What you need to know for your flight from Mobile Regional to O'Hare Intl.

Mobile (MOB) to Chicago (ORD) at a glance

Travel between Mobile (MOB) and Chicago (ORD) with a selection of airlines catering to this domestic short-haul route. Discover cheap flights from Mobile to Chicago as you compare various options, ranging from full-service carriers to budget-friendly choices. This will help you find the ideal itinerary that aligns with your budget and travel plans while you explore Chicago’s iconic attractions and vibrant neighborhoods. Get all the essential details for flights from Mobile Regional Airport to O'Hare International Airport.

  • Fastest flight duration: around 4h 15m in-flight, plus roughly 1h 15m layover with one stop
  • Route distance: roughly 800 miles (1,290 km)
  • Flights per week: around 10 departures on average
  • Typical fares (one-way): economy tickets often range from $125–$375, depending on seasonality and how far ahead you book

Flights from Mobile Regional Airport (MOB) to O'Hare International Airport (ORD)

Based on the latest traveler bookings, here are the most popular airlines for flights from Mobile to Chicago, often selected for their one-stop services. Common layover airports include Hartsfield-Jackson Atlanta International Airport (ATL) with a layover of about 1 hour and 15 minutes, Charlotte-Douglas International Airport (CLT) also around 1 hour and 15 minutes, and Dallas-Fort Worth International Airport (DFW), similarly approximately 1 hour and 15 minutes. These options allow you to balance price, total travel time, and cabin class to create your ideal itinerary.

  • American Airlines: This full-service airline provides one-stop flights, with one-way ticket prices generally falling between $125 and $355. It operates about 45% of the flights on this route, featuring an in-flight duration of 4 hours and 15 minutes, and a total travel time of approximately 5 hours and 15 minutes, including layovers.
  • Delta: Offering a full-service experience, Delta presents one-stop options, with one-way fares typically ranging from $125 to $410. It accounts for around 39% of departures on this route, with an in-flight time of 4 hours and 15 minutes, leading to a total journey length of about 5 hours and 15 minutes, including stops.
  • United: This full-service airline also offers one-stop services, with one-way fares usually priced between $150 and $470. United represents approximately 15% of the departures on this route, featuring an in-flight time of 4 hours and 15 minutes, and a total travel duration of roughly 5 hours and 15 minutes, factoring in layovers.

Travelers can enhance their journey from Mobile to Chicago by upgrading to premium economy class, available on this route through Delta, ensuring a more comfortable flying experience.

Best time to fly from Mobile (MOB) to Chicago (ORD)

The most popular months for travelers flying from Mobile to Chicago are January, March, and April, when peak temperatures in Chicago reach up to 46°F in April. If you prefer quieter travel, consider December, the least busy and relatively cheaper time to visit with fewer crowds and temperatures around 33.1°F. For better deals, May and June usually offer the lowest average one-way fares around $199. Flight availability peaks in June, with approximately 12 flights per week, making it easier to find convenient departure times. February has the fewest flights, with approximately 8 flights per week.

  • Cheapest time to fly: May and June usually offer good deals with average one-way fares around $199, roughly 16% cheaper than the yearly average.
  • More budget-friendly months to fly: August and December typically offer average one-way fares of around $214.
  • Most flight options: June has the highest number of flights from Mobile to Chicago, with approximately 12 flights per week, giving you more flexibility in scheduling your trip.
calendar iconMonthtemperature iconTemperaturecrowd level iconDemandflights iconWeekly Flightsprice iconAverage one-way Fare
January25.7°F (-3.5°C)Moderately High9$250
February27.0°F (-2.8°C)Average8$270
March37.0°F (2.8°C)Moderately High10$266
April46.0°F (7.8°C)Moderately High9$243
May57.0°F (13.9°C)Average9$199
June67.3°F (19.6°C)Average12$199
July73.4°F (23.0°C)Moderately Low11$248
August73.0°F (22.8°C)Average11$211
September67.1°F (19.5°C)Average10$256
October54.9°F (12.7°C)Average11$265
November42.3°F (5.7°C)Moderately Low10$228
December33.1°F (0.6°C)Moderately Low11$217

*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.

Alternative routes from Mobile (MOB) to Chicago (ORD)

  • Mobile to Chicago (MOB-MDW): Midway International Airport (MDW) is located approximately 16 miles from O'Hare International Airport (ORD). One-way economy ticket prices for this route generally fall between $120 and $380, influenced by the time of year and how far in advance you book. Travelers will often find one-stop options available, with most connections occurring through Hartsfield-Jackson Atlanta International Airport (ATL). Major airlines operating on this route include Delta and KLM, with first-class service also offered.
  • Pensacola to Chicago (PNS-ORD): Pensacola International Airport (PNS) is roughly 64 miles from Mobile Regional Airport (MOB). The one-way economy fares for this route usually range from $100 to $340, varying based on seasonal demand and booking time. Both non-stop and one-stop flight options are commonly available. Key airlines for this route include United and American Airlines, and travelers can also choose first-class service.

How to find the best prices for flights from Mobile (MOB) to Chicago (ORD)

Getting some of the best deals on flights from Mobile to Chicago is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are usually available when booking 2 to 8 weeks in advance, although most travelers tend to book within 2 weeks. Departures in the afternoon (12 PM to 6 PM) often offer lower prices, while morning flights (5 AM to 12 PM) are more popular. Additionally, flying on Tuesday generally provides cheaper rates, though Wednesday is the most common travel day.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.*
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at O'Hare International Airport from Mobile Regional Airport

Chicago welcomes travelers from Mobile with a range of transport options based on price, convenience, and proximity. Here's how to reach Chicago efficiently:

  • Hotel transfer: Transfers offer a convenient way to reach your hotel in Chicago, with private rides that can be arranged in advance.
  • Car rental: Renting a car from O'Hare International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at O'Hare International Airport on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.
  • Public transportation: From O'Hare International Airport, O'Hare Station, a metro station, is located just 0.1 miles away on foot, while Rosemont Station, a train station, is about 2.2 miles from the airport and typically reached by car.

Frequently asked questions

How much does a flight from Mobile, AL (MOB-Mobile Regional) to Chicago, IL (ORD-O'Hare Intl.) cost?
You can find cheap one-way flights from $154 and cheap return flights from $313 Mobile, AL (MOB-Mobile Regional) to Chicago, IL (ORD-O'Hare Intl.) with Expedia. One-way flights typically cost between $202 and $743, and return flights often range between $428 and $1280. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Mobile, AL (MOB-Mobile Regional) to Chicago, IL (ORD-O'Hare Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Mobile, AL (MOB-Mobile Regional) to Chicago, IL (ORD-O'Hare Intl.)?
May is the cheapest month to fly from Mobile (MOB) to Chicago (ORD), with average return fares around $343. This is about 18% lower than the average price throughout the year, as demand is typically lower in the spring. You might also find good deals in February and August.*Averages based on flights available on Expedia in the last year.
Which airlines fly direct from Mobile, AL (MOB-Mobile Regional) to Chicago, IL (ORD-O'Hare Intl.)?
Enter MOB to ORD and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Mobile, AL (MOB-Mobile Regional) to Chicago, IL (ORD-O'Hare Intl.)?
American Airlines is one of the cheapest airlines offering connecting flights from Mobile (MOB) to Chicago (ORD), with round-trip tickets starting from around $253 with a layover in Charlotte-Douglas Intl. (CLT). Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Mobile, AL (MOB-Mobile Regional) to Chicago, IL (ORD-O'Hare Intl.)?
To find a cheap flight from Mobile, AL (MOB-Mobile Regional) to Chicago, IL (ORD-O'Hare Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Mobile, AL (MOB-Mobile Regional) to Chicago, IL (ORD-O'Hare Intl.)?
For flights from Mobile, AL (MOB) to Chicago, IL (ORD), May is a fantastic time to travel, with return flights averaging around $343. This month is popular for its pleasant weather and offers a good mix of affordability and flight availability, making it a great choice for your trip.*Prices based on flights available on Expedia in the last year.
What is the earliest flight from Mobile, AL (MOB-Mobile Regional) to Chicago, IL (ORD-O'Hare Intl.)?
The earliest flight from Mobile Regional Airport (MOB) to O'Hare International Airport (ORD) typically departs at around 5:00 AM, operated by American Airlines. This seasonal service is available in May, allowing you to start your day early and make the most of your time in Chicago. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Mobile, AL (MOB-Mobile Regional) to Chicago, IL (ORD-O'Hare Intl.)?
The most popular departure times for flights from Mobile (MOB) to Chicago (ORD) are from 3pm to 6pm. About 24% of passengers prefer this time window. Many major carriers, including American Airlines and United Airlines, offer flights during this window. This timing is popular because it allows you to enjoy your day in Mobile before heading to Chicago.
How long does it take to fly from Mobile, AL (MOB-Mobile Regional) to Chicago, IL (ORD-O'Hare Intl.)?
Flying from MOB to ORD with a connection usually takes about 5 hours 50 minutes, traveling roughly 781 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Mobile, AL (MOB-Mobile Regional) to Chicago, IL (ORD-O'Hare Intl.)?
First class seats are offered on the MOB to ORD route. First class cabins are available on:

  • Delta Air Lines
  • American Airlines
  • United Airlines

How do I earn miles on a Mobile, AL (MOB-Mobile Regional) to Chicago, IL (ORD-O'Hare Intl.) flight with Expedia?
It's easy to earn miles on a Mobile, AL (MOB-Mobile Regional) to Chicago, IL (ORD-O'Hare Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Chicago from Mobile Regional (MOB)?
When traveling from Mobile Regional (MOB) to Chicago, you can fly into Midway Intl. (MDW) and O'Hare Intl. (ORD). Some flights may connect through major hubs like Washington Dulles Intl. (IAD), George Bush Intercontinental (IAH), Hartsfield-Jackson Atlanta Intl. (ATL) before reaching Chicago. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Mobile, AL (MOB-Mobile Regional) to Chicago, IL (ORD-O'Hare Intl.) at the last minute?
Typically, booking a last minute flight from Mobile, AL (MOB-Mobile Regional) to Chicago, IL (ORD-O'Hare Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Mobile, AL (MOB-Mobile Regional) to Chicago, IL (ORD-O'Hare Intl.) flight and hotel package?
Securing a Mobile, AL (MOB-Mobile Regional) to Chicago, IL (ORD-O'Hare Intl.) Chicago Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Mobile, AL (MOB-Mobile Regional) to Chicago, IL (ORD-O'Hare Intl.)?
If you booked your Mobile, AL (MOB-Mobile Regional) to Chicago, IL (ORD-O'Hare Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Mobile Regional
Destination airport
O'Hare Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$312
Distance
780 mi

Book with confidence

Mobile to Chicago Flights

The cheapest times to fly from Mobile to Chicago

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Mobile to Chicago are during the month of September. You can find some of the cheapest flights from Mobile to Chicago with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Mobile to Chicago

Sunday is one of the best days to book for cheap flights from Mobile to Chicago: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Mobile to Chicago

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Mobile to Chicago in 2026. You can also book with separate airlines for your outbound and return journeys, from $154 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Mobile to Chicago flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Mobile to Chicago airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Mobile to Chicago Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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