$320 Cheap Flights from Ponce (PSE) to Santiago (STI)

View $320 flight on Fri, Nov 21, 2025Opens in a new window

Popular airlines from Ponce (PSE-Mercedita) to Cibao Intl. Airport (STI)

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Cheap Flights from Ponce to Santiago (PSE-STI)

Prices were available within the past 7 days and start at $320 for one-way flights and $442 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

JetBlue Airways
Thu, Nov 13 - Tue, Nov 18
PSE
Ponce
STI
Santiago de los Caballeros
$442 Roundtrip, found 5 days ago
$442
Roundtrip
found 5 days ago
Select JetBlue Airways flight, departing Thu, Nov 13 from Ponce to Santiago de los Caballeros, returning Tue, Nov 18, priced at $442 found 5 days ago
JetBlue Airways
Sun, Nov 9 - Sat, Nov 15
PSE
Ponce
STI
Santiago de los Caballeros
$487 Roundtrip, found 5 days ago
$487
Roundtrip
found 5 days ago
Select JetBlue Airways flight, departing Sun, Nov 9 from Ponce to Santiago de los Caballeros, returning Sat, Nov 15, priced at $487 found 5 days ago
JetBlue Airways
Thu, Nov 13 - Thu, Nov 20
PSE
Ponce
STI
Santiago de los Caballeros
$497 Roundtrip, found 5 days ago
$497
Roundtrip
found 5 days ago
Select JetBlue Airways flight, departing Thu, Nov 13 from Ponce to Santiago de los Caballeros, returning Thu, Nov 20, priced at $497 found 5 days ago
JetBlue Airways
Mon, Nov 10 - Sat, Nov 15
PSE
Ponce
STI
Santiago de los Caballeros
$502 Roundtrip, found 5 days ago
$502
Roundtrip
found 5 days ago
Select JetBlue Airways flight, departing Mon, Nov 10 from Ponce to Santiago de los Caballeros, returning Sat, Nov 15, priced at $502 found 5 days ago
JetBlue Airways
Wed, Nov 12 - Sat, Nov 15
PSE
Ponce
STI
Santiago de los Caballeros
$507 Roundtrip, found 5 days ago
$507
Roundtrip
found 5 days ago
Select JetBlue Airways flight, departing Wed, Nov 12 from Ponce to Santiago de los Caballeros, returning Sat, Nov 15, priced at $507 found 5 days ago
JetBlue Airways
Fri, Nov 14 - Tue, Nov 18
PSE
Ponce
STI
Santiago de los Caballeros
$542 Roundtrip, found 5 days ago
$542
Roundtrip
found 5 days ago
Select JetBlue Airways flight, departing Fri, Nov 14 from Ponce to Santiago de los Caballeros, returning Tue, Nov 18, priced at $542 found 5 days ago
JetBlue Airways
Wed, Nov 12 - Thu, Nov 20
PSE
Ponce
STI
Santiago de los Caballeros
$546 Roundtrip, found 5 days ago
$546
Roundtrip
found 5 days ago
Select JetBlue Airways flight, departing Wed, Nov 12 from Ponce to Santiago de los Caballeros, returning Thu, Nov 20, priced at $546 found 5 days ago
JetBlue Airways
Thu, Nov 13 - Mon, Nov 17
PSE
Ponce
STI
Santiago de los Caballeros
$557 Roundtrip, found 5 days ago
$557
Roundtrip
found 5 days ago
Select JetBlue Airways flight, departing Thu, Nov 13 from Ponce to Santiago de los Caballeros, returning Mon, Nov 17, priced at $557 found 5 days ago
JetBlue Airways
Thu, Nov 13 - Sat, Nov 22
PSE
Ponce
STI
Santiago de los Caballeros
$558 Roundtrip, found 5 days ago
$558
Roundtrip
found 5 days ago
Select JetBlue Airways flight, departing Thu, Nov 13 from Ponce to Santiago de los Caballeros, returning Sat, Nov 22, priced at $558 found 5 days ago
JetBlue Airways
Sat, Nov 15 - Tue, Nov 18
PSE
Ponce
STI
Santiago de los Caballeros
$562 Roundtrip, found 5 days ago
$562
Roundtrip
found 5 days ago
Select JetBlue Airways flight, departing Sat, Nov 15 from Ponce to Santiago de los Caballeros, returning Tue, Nov 18, priced at $562 found 5 days ago

Frequently asked questions

How much does a flight from Mercedita Airport (PSE) to Cibao Intl. Airport (STI) cost?
Lock in a cheap one-way flight from $320 or cheap return flight from $442 from Mercedita Airport (PSE) to Cibao Intl. Airport (STI) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Mercedita Airport (PSE) to Cibao Intl. Airport (STI)?
The cheapest month to fly from PSE to STI is November, when demand is low. Off-peak season is typically when you'll find cheap fares for travel between these airports.
Which airlines fly direct from Mercedita Airport (PSE) to Cibao Intl. Airport (STI)?
Although Ponce (PSE-Mercedita) has no direct flights to Cibao Intl. Airport (STI), other airports have nonstop routes. Leaving from Luis Munoz Marin Intl. Airport (SJU) will get you to Santiago de los Caballeros without any detours.
What is the cheapest airline that flies from Mercedita Airport (PSE) to Cibao Intl. Airport (STI)?
Use the filters on Expedia to compare airlines and find the cheapest carrier that'll fly you from PSE to STI. Then, sort your results by "Price (lowest to highest)" to pick up a good deal.
How many flights per day from Mercedita Airport (PSE) to Cibao Intl. Airport (STI)?
You'll have to hop on a flight with a layover when traveling from Mercedita Airport (PSE) to Cibao Intl. Airport (STI). There are no daily direct flights on this route. However, just filter your search to include one or two stops to discover the best option for your trip.
What day of the week has the most flights from PSE to STI?
You'll usually find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can vary from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Mercedita Airport (PSE) to Cibao Intl. Airport (STI)?
To reach Cibao Intl. Airport (STI) without delays, book a flight that leaves from Mercedita Airport (PSE) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Mercedita Airport (PSE) to Cibao Intl. Airport (STI) last-minute?
Last-minute bookings from PSE to STI are typically more expensive. For the best rates, start looking for flights early. That being said, if you're flexible with your travel dates, you may score a cheap fare right before you leave.
Is it cheaper to book a PSE to STI flight and hotel package?
Securing a PSE to STI flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Choose from our wide range of hotels and then add activities, flights and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Mercedita Airport (PSE) to Cibao Intl. Airport (STI)?
In most cases, you can modify or cancel your PSE to STI flight. However, there may be additional charges, especially if your booking was made more than 24 hours ago. Double-check your itinerary for the airline's fees and guidelines on flight changes, or if you'd like further details, go to our Customer Service portal.

Travel information

Origin airport
Mercedita
Destination airport
Cibao Intl.
Roundtrip price
$442
Distance
281 mi

Book with confidence

Ponce to Santiago Flights

The cheapest times to fly from Ponce to Santiago

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Ponce to Santiago are during the month of November. You can find some of the cheapest flights from Ponce to Santiago with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Ponce to Santiago

Sunday is one of the best days to book for cheap flights from Ponce to Santiago: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Ponce to Santiago

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Ponce to Santiago in 2025. You can also book with separate airlines for your outbound and return journeys, from $320 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Ponce to Santiago flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Ponce to Santiago airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Ponce to Santiago Flights

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*Available to One Key members.