$199 Cheap Flights from Santiago (STI) to Medellín (MDE)

View $199 flight on Mon, Jan 26, 2026Opens in a new window

Popular airlines from Cibao Intl. Airport (STI) to Jose Maria Cordova Intl. Airport (MDE)

Cheap Flights from Santiago to Medellín (STI-MDE)

Prices were available within the past 7 days and start at $199 for one-way flights and $421 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Mon, Jan 26 - Sat, Jan 31
STI
Santiago de los Caballeros
MDE
Medellin
$421 Roundtrip, found 8 hours ago
$421
Roundtrip
found 8 hours ago
Select Copa flight, departing Mon, Jan 26 from Santiago de los Caballeros to Medellin, returning Sat, Jan 31, priced at $421 found 8 hours ago
Copa
Mon, Jan 26 - Sat, Jan 31
STI
Santiago de los Caballeros
MDE
Medellin
$456 Roundtrip, found 8 hours ago
$456
Roundtrip
found 8 hours ago
Select Copa flight, departing Mon, Jan 26 from Santiago de los Caballeros to Medellin, returning Sat, Jan 31, priced at $456 found 8 hours ago
Copa
Sat, Feb 14 - Sun, Feb 15
STI
Santiago de los Caballeros
MDE
Medellin
$468 Roundtrip, found 14 hours ago
$468
Roundtrip
found 14 hours ago
Select Copa flight, departing Sat, Feb 14 from Santiago de los Caballeros to Medellin, returning Sun, Feb 15, priced at $468 found 14 hours ago
Copa
Mon, Jan 26 - Sat, Jan 31
STI
Santiago de los Caballeros
MDE
Medellin
$473 Roundtrip, found 8 hours ago
$473
Roundtrip
found 8 hours ago
Select Copa flight, departing Mon, Jan 26 from Santiago de los Caballeros to Medellin, returning Sat, Jan 31, priced at $473 found 8 hours ago
Copa
Sat, Feb 21 - Mon, Feb 23
STI
Santiago de los Caballeros
MDE
Medellin
$485 Roundtrip, found 5 days ago
$485
Roundtrip
found 5 days ago
Select Copa flight, departing Sat, Feb 21 from Santiago de los Caballeros to Medellin, returning Mon, Feb 23, priced at $485 found 5 days ago
Copa
Thu, Jan 15 - Sat, Jan 31
STI
Santiago de los Caballeros
MDE
Medellin
$504 Roundtrip, found 3 days ago
$504
Roundtrip
found 3 days ago
Select Copa flight, departing Thu, Jan 15 from Santiago de los Caballeros to Medellin, returning Sat, Jan 31, priced at $504 found 3 days ago
Copa
Mon, Jan 19 - Sat, Jan 24
STI
Santiago de los Caballeros
MDE
Medellin
$512 Roundtrip, found 1 day ago
$512
Roundtrip
found 1 day ago
Select Copa flight, departing Mon, Jan 19 from Santiago de los Caballeros to Medellin, returning Sat, Jan 24, priced at $512 found 1 day ago
JetBlue Airways
Tue, Jan 27 - Thu, Feb 12
STI
Santiago de los Caballeros
MDE
Medellin
$566 Roundtrip, found 1 day ago
$566
Roundtrip
found 1 day ago
Select JetBlue Airways flight, departing Tue, Jan 27 from Santiago de los Caballeros to Medellin, returning Thu, Feb 12, priced at $566 found 1 day ago
United
Wed, Nov 12 - Wed, Nov 19
STI
Santiago de los Caballeros
MDE
Medellin
$718 Roundtrip, found 3 days ago
$718
Roundtrip
found 3 days ago
Select United flight, departing Wed, Nov 12 from Santiago de los Caballeros to Medellin, returning Wed, Nov 19, priced at $718 found 3 days ago
American Airlines
Thu, Jan 22 - Thu, Jan 29
STI
Santiago de los Caballeros
MDE
Medellin
$1,157 Roundtrip, found 5 hours ago
$1,157
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Thu, Jan 22 from Santiago de los Caballeros to Medellin, returning Thu, Jan 29, priced at $1,157 found 5 hours ago

Find the cheapest month to fly from Santiago de los Caballeros (STI) to Medellín (MDE)

February is typically the cheapest month to fly

From $258 - $1,019 per traveler.

Alternative airports near Medellín

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Jose Maria Cordova Intl. MDE. Cheapest option available. Average driving time to city center is 29 minutes. Flights from $730
MDE
Jose Maria Cordova Intl.
Cheapest
Average driving time to city center29 min
Flights from $730

Frequently asked questions

How much does a flight from Cibao Intl. Airport (STI) to Jose Maria Cordova Intl. Airport (MDE) cost?
Lock in a cheap one-way flight from $199 or cheap return flight from $421 from Cibao Intl. Airport (STI) to Jose Maria Cordova Intl. Airport (MDE) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Cibao Intl. Airport (STI) to Jose Maria Cordova Intl. Airport (MDE)?
January is the most affordable month to fly from STI to MDE. Traveling outside of peak seasons is often the key to scoring lower fares.
Which airlines fly direct from Cibao Intl. Airport (STI) to Jose Maria Cordova Intl. Airport (MDE)?
Jump on a nonstop flight with Arajet and head straight from Cibao Intl. Airport (STI) to Jose Maria Cordova Intl. Airport (MDE).
What is the cheapest airline that flies from Cibao Intl. Airport (STI) to Jose Maria Cordova Intl. Airport (MDE)?
Expedia's filter tool lets you easily compare airlines, flight times and baggage options all in one place. Customize the search to your preferences, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest STI to MDE flight.
How many flights per day from Cibao Intl. Airport (STI) to Jose Maria Cordova Intl. Airport (MDE)?
On average, Cibao Intl. Airport (STI) has 2 nonstop flights to Jose Maria Cordova Intl. Airport (MDE) each week. If you want more options, use Expedia's filters to discover flights with layovers. Squeeze in a quick visit to another destination or simply break up your journey.
What are the most popular departure times for flights from Cibao Intl. Airport (STI) to Jose Maria Cordova Intl. Airport (MDE)?
More travelers fly between STI and MDE at 8 AM than at any other time. Looking for a quieter experience? Consider flying outside peak hours and it's possible you'll save on your fare as well.
What day of the week has the most flights from STI to MDE?
Thursday has the most flights from Cibao Intl. Airport (STI) to Jose Maria Cordova Intl. Airport (MDE). Consider jetting off on this day and you'll have a greater chance of finding a departure that fits your plans.
What is the earliest flight from Cibao Intl. Airport (STI) to Jose Maria Cordova Intl. Airport (MDE)?
Cibao Intl. Airport (STI)'s earliest flight to Jose Maria Cordova Intl. Airport (MDE) is at approximately 8:30AM UTC-4. With a flight time of 2h 35m, you'll arrive at around 10:05AM UTC-5.
How long does it take to fly from Cibao Intl. Airport (STI) to Jose Maria Cordova Intl. Airport (MDE)?
The average flight duration from STI to MDE is 2 hours and 35 minutes, covering a total distance of 970 mi.
What airline has the least delays from STI to MDE?
With 100% of journeys usually landing on time, Arajet has the best on-time performance for direct flights from Cibao Intl. Airport (STI) to Jose Maria Cordova Intl. Airport (MDE). To keep track of your flight status and receive notifications if anything changes, use the Expedia App.
What is the best time to fly from Cibao Intl. Airport (STI) to Jose Maria Cordova Intl. Airport (MDE)?
Select a flight from Cibao Intl. Airport (STI) to Jose Maria Cordova Intl. Airport (MDE) that leaves before 3 PM to reduce the likelihood of delays. Departures later than this are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Medellin from Cibao Intl. Airport (STI)?
Check out your flight options from Cibao Intl. Airport (STI) to Jose Maria Cordova Intl. Airport (MDE). This is the only Medellin airport you can land at if you're taking a direct flight.
Is it cheaper to buy a plane ticket from Cibao Intl. Airport (STI) to Jose Maria Cordova Intl. Airport (MDE) last-minute?
Holding off until just before your departure to book your flight from STI to MDE often results in higher prices. While you might find some last-minute deals, there's no guarantee. Keep your travel plans flexible to maximize your chances of snagging a bargain.
Is it cheaper to book a STI to MDE flight and hotel package?
You'll generally save money by securing a STI to MDE flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's simple to manage everything in one place. Once you've selected your preferred accommodations and flights, you can add extras such as car rentals, tours and activities.
Can I cancel or change the date of my flight from Cibao Intl. Airport (STI) to Jose Maria Cordova Intl. Airport (MDE)?
If you reserved your STI to MDE flight in the last 24 hours, you may be able to cancel or modify it without fees. Depending on the airline and the type of fare you purchased, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Cibao Intl.
Destination airport
José María Córdova Intl.
Airlines serving
American Airlines, Copa, JetBlue Airways, United
Roundtrip price
$420
Distance
969 mi

Book with confidence

Santiago to Medellín Flights

The cheapest times to fly from Santiago to Medellín

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Santiago to Medellín are during the month of January. You can find some of the cheapest flights from Santiago to Medellín with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Santiago to Medellín

Sunday is one of the best days to book for cheap flights from Santiago to Medellín: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Santiago to Medellín

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Santiago to Medellín in 2025. You can also book with separate airlines for your outbound and return journeys, from $199 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Santiago to Medellín flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Santiago to Medellín airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Santiago to Medellín Flights

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*Available to One Key members.