$134 Cheap Flights from St. Louis (STL) to Greenville (GSP)

View $134 flight on Thu, Nov 27, 2025Opens in a new window

Popular airlines from St. Louis Lambert Intl. Airport (STL) to Greenville-Spartanburg Intl. Airport (GSP)

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Cheap Flights from St. Louis to Greenville (STL-GSP)

Prices were available within the past 7 days and start at $134 for one-way flights and $267 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Mon, Nov 24 - Thu, Nov 27
STL
St. Louis
GSP
Greenville
$267 Roundtrip, found 1 day ago
$267
Roundtrip
found 1 day ago
Select Delta flight, departing Mon, Nov 24 from St. Louis to Greenville, returning Thu, Nov 27, priced at $267 found 1 day ago
American Airlines
Sat, Jan 17 - Wed, Jan 21
STL
St. Louis
GSP
Greenville
$277 Roundtrip, found 5 days ago
$277
Roundtrip
found 5 days ago
Select American Airlines flight, departing Sat, Jan 17 from St. Louis to Greenville, returning Wed, Jan 21, priced at $277 found 5 days ago
Southwest Airlines
Sat, Jan 17 - Wed, Jan 21
STL
St. Louis
GSP
Greenville
$277 Roundtrip, found 5 days ago
$277
Roundtrip
found 5 days ago
Select Southwest Airlines flight, departing Sat, Jan 17 from St. Louis to Greenville, returning Wed, Jan 21, priced at $277 found 5 days ago
American Airlines
Sat, Jan 17 - Wed, Jan 21
STL
St. Louis
GSP
Greenville
$279 Roundtrip, found 5 days ago
$279
Roundtrip
found 5 days ago
Select American Airlines flight, departing Sat, Jan 17 from St. Louis to Greenville, returning Wed, Jan 21, priced at $279 found 5 days ago
Delta
Tue, Jan 20 - Thu, Jan 22
STL
St. Louis
GSP
Greenville
$288 Roundtrip, found 5 days ago
$288
Roundtrip
found 5 days ago
Select Delta flight, departing Tue, Jan 20 from St. Louis to Greenville, returning Thu, Jan 22, priced at $288 found 5 days ago
American Airlines
Sat, Jan 17 - Wed, Jan 21
STL
St. Louis
GSP
Greenville
$289 Roundtrip, found 5 days ago
$289
Roundtrip
found 5 days ago
Select American Airlines flight, departing Sat, Jan 17 from St. Louis to Greenville, returning Wed, Jan 21, priced at $289 found 5 days ago
United
Sat, Jan 17 - Wed, Jan 21
STL
St. Louis
GSP
Greenville
$307 Roundtrip, found 5 days ago
$307
Roundtrip
found 5 days ago
Select United flight, departing Sat, Jan 17 from St. Louis to Greenville, returning Wed, Jan 21, priced at $307 found 5 days ago
United
Tue, Feb 3 - Thu, Feb 5
STL
St. Louis
GSP
Greenville
$308 Roundtrip, found 1 hour ago
$308
Roundtrip
found 1 hour ago
Select United flight, departing Tue, Feb 3 from St. Louis to Greenville, returning Thu, Feb 5, priced at $308 found 1 hour ago
American Airlines
Thu, Jan 8 - Mon, Jan 12
STL
St. Louis
GSP
Greenville
$310 Roundtrip, found 1 day ago
$310
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, Jan 8 from St. Louis to Greenville, returning Mon, Jan 12, priced at $310 found 1 day ago
Southwest Airlines
Sat, Jan 17 - Wed, Jan 21
STL
St. Louis
GSP
Greenville
$312 Roundtrip, found 5 days ago
$312
Roundtrip
found 5 days ago
Select Southwest Airlines flight, departing Sat, Jan 17 from St. Louis to Greenville, returning Wed, Jan 21, priced at $312 found 5 days ago

Find the cheapest month to fly from St. Louis (STL) to Greenville (GSP)

August is typically the cheapest month to fly

From $191 - $526 per traveler.

Alternative airports near Greenville

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Greenville-Spartanburg Intl. GSP. Cheapest option available. Average driving time to city center is 18 minutes. Flights from $417
GSP
Greenville-Spartanburg Intl.
Cheapest
Average driving time to city center18 min
Flights from $417

Frequently asked questions

How much does a flight from Lambert-St. Louis Intl. Airport (STL) to Greenville-Spartanburg Intl. Airport (GSP) cost?
Lock in a cheap one-way flight from $134 or cheap return flight from $267 from Lambert-St. Louis Intl. Airport (STL) to Greenville-Spartanburg Intl. Airport (GSP) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Lambert-St. Louis Intl. Airport (STL) to Greenville-Spartanburg Intl. Airport (GSP)?
November is the cheapest month to fly from STL to GSP. Planning your trip for the off-season is often the key to finding a great deal.
What is the cheapest airline that flies from Lambert-St. Louis Intl. Airport (STL) to Greenville-Spartanburg Intl. Airport (GSP)?
Use the filter tool on Expedia to compare airlines and find the most affordable carrier that'll take you from STL to GSP. Then, sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from Lambert-St. Louis Intl. Airport (STL) to Greenville-Spartanburg Intl. Airport (GSP)?
Nonstop flights from Lambert-St. Louis Intl. Airport (STL) to Greenville-Spartanburg Intl. Airport (GSP) aren't available daily, so you'll have to take a flight with a layover. Explore your options with Expedia's filters. Enter your travel details and click on either "1 Stop" or "2+ Stops."
What day of the week has the most flights from STL to GSP?
Generally you'll find the widest variety of flight choices on a Friday. Tuesdays tend to be the quietest.* However, this can change depending on the time of year, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Lambert-St. Louis Intl. Airport (STL) to Greenville-Spartanburg Intl. Airport (GSP)?
To avoid potential delays on the Lambert-St. Louis Intl. Airport (STL) to Greenville-Spartanburg Intl. Airport (GSP) route, aim to travel before 3 PM. Departures after this hour have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Lambert-St. Louis Intl. Airport (STL) to Greenville-Spartanburg Intl. Airport (GSP) last-minute?
Booking your plane ticket from STL to GSP right before your getaway is typically more expensive. However, if there's some wiggle room with your travel times and dates, you could grab a cheap last-minute fare.
Is it cheaper to book a STL to GSP flight and hotel package?
You'll generally save money by securing a STL to GSP flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's easy to manage it all in one place. After selecting your ideal flights and accommodations, you can add extras like tours, activities and car rentals.
Can I cancel or change the date of my flight from Lambert-St. Louis Intl. Airport (STL) to Greenville-Spartanburg Intl. Airport (GSP)?
In most cases, you can reschedule or cancel your STL to GSP flight. However, there may be additional fees, especially if you made your booking over 24 hours ago. Double-check your itinerary for the airline's guidelines and fees on flight changes, or if you want further details, head to our Customer Service portal.

Travel information

Origin airport
Lambert-St. Louis Intl.
Destination airport
Greenville-Spartanburg Intl.
Airlines serving
American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$266
Distance
523 mi

Book with confidence

St. Louis to Greenville Flights

The cheapest times to fly from St. Louis to Greenville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from St. Louis to Greenville are during the month of November. You can find some of the cheapest flights from St. Louis to Greenville with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from St. Louis to Greenville

Sunday is one of the best days to book for cheap flights from St. Louis to Greenville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from St. Louis to Greenville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from St. Louis to Greenville in 2025. You can also book with separate airlines for your outbound and return journeys, from $134 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap St. Louis to Greenville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your St. Louis to Greenville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

St. Louis to Greenville Flights

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*Available to One Key members.