$365 Cheap Flights from Tyler (TYR) to Greenville (GSP)

View $365 flight on Tue, Nov 11, 2025Opens in a new window

Popular airlines from Tyler, TX (TYR-Pounds Regional) to Greenville-Spartanburg Intl. Airport (GSP)

Cheap Flights from Tyler to Greenville (TYR-GSP)

Prices were available within the past 7 days and start at $365 for one-way flights and $458 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Fri, Aug 7 - Sun, Aug 9
TYR
Tyler
GSP
Greenville
$458 Roundtrip, found 5 days ago
$458
Roundtrip
found 5 days ago
Select American Airlines flight, departing Fri, Aug 7 from Tyler to Greenville, returning Sun, Aug 9, priced at $458 found 5 days ago
American Airlines
Wed, Nov 26 - Sat, Dec 6
TYR
Tyler
GSP
Greenville
$464 Roundtrip, found 6 hours ago
$464
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Wed, Nov 26 from Tyler to Greenville, returning Sat, Dec 6, priced at $464 found 6 hours ago
American Airlines
Sat, Oct 25 - Sat, Nov 8
TYR
Tyler
GSP
Greenville
$473 Roundtrip, found 6 hours ago
$473
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Sat, Oct 25 from Tyler to Greenville, returning Sat, Nov 8, priced at $473 found 6 hours ago
American Airlines
Wed, Nov 26 - Sun, Dec 7
TYR
Tyler
GSP
Greenville
$483 Roundtrip, found 6 hours ago
$483
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Wed, Nov 26 from Tyler to Greenville, returning Sun, Dec 7, priced at $483 found 6 hours ago
American Airlines
Sat, Oct 11 - Tue, Oct 28
TYR
Tyler
GSP
Greenville
$488 Roundtrip, found 6 hours ago
$488
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Sat, Oct 11 from Tyler to Greenville, returning Tue, Oct 28, priced at $488 found 6 hours ago
American Airlines
Tue, Nov 11 - Tue, Nov 25
TYR
Tyler
GSP
Greenville
$491 Roundtrip, found 6 hours ago
$491
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Tue, Nov 11 from Tyler to Greenville, returning Tue, Nov 25, priced at $491 found 6 hours ago
American Airlines
Thu, Oct 16 - Thu, Oct 23
TYR
Tyler
GSP
Greenville
$492 Roundtrip, found 6 days ago
$492
Roundtrip
found 6 days ago
Select American Airlines flight, departing Thu, Oct 16 from Tyler to Greenville, returning Thu, Oct 23, priced at $492 found 6 days ago
American Airlines
Sat, Oct 18 - Sat, Nov 1
TYR
Tyler
GSP
Greenville
$494 Roundtrip, found 6 hours ago
$494
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Sat, Oct 18 from Tyler to Greenville, returning Sat, Nov 1, priced at $494 found 6 hours ago
American Airlines
Sun, Nov 2 - Sat, Nov 15
TYR
Tyler
GSP
Greenville
$494 Roundtrip, found 6 hours ago
$494
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Sun, Nov 2 from Tyler to Greenville, returning Sat, Nov 15, priced at $494 found 6 hours ago
American Airlines
Wed, Dec 3 - Wed, Dec 17
TYR
Tyler
GSP
Greenville
$497 Roundtrip, found 6 hours ago
$497
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Wed, Dec 3 from Tyler to Greenville, returning Wed, Dec 17, priced at $497 found 6 hours ago

Alternative airports near Greenville

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Greenville-Spartanburg Intl. GSP. Cheapest option available. Average driving time to city center is 18 minutes. Flights from $510
GSP
Greenville-Spartanburg Intl.
Cheapest
Average driving time to city center18 min
Flights from $510

Frequently asked questions

How much does a flight from Pounds Regional Airport (TYR) to Greenville-Spartanburg Intl. Airport (GSP) cost?
Secure a cheap one-way flight from $365 or cheap return flight from $458 from Pounds Regional Airport (TYR) to Greenville-Spartanburg Intl. Airport (GSP) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Pounds Regional Airport (TYR) to Greenville-Spartanburg Intl. Airport (GSP)?
August is the least expensive month to fly from TYR to GSP. Traveling outside of peak seasons is often the key to finding better deals on flights.
What is the cheapest airline that flies from Pounds Regional Airport (TYR) to Greenville-Spartanburg Intl. Airport (GSP)?
Expedia's filter tool lets you easily compare travel time, airlines and fares all in one place. Customize the search to your preferences, then sort by "Price (lowest to highest)" to find the carrier with the cheapest TYR to GSP flight.
How many flights per day from Pounds Regional Airport (TYR) to Greenville-Spartanburg Intl. Airport (GSP)?
There are no daily direct flights departing from Pounds Regional Airport (TYR) to Greenville-Spartanburg Intl. Airport (GSP). But you can opt for flights with layovers. Filter your search on Expedia to include one or two stops, and you'll be cruising above the clouds before you know it.
What day of the week has the most flights from TYR to GSP?
Typically you'll find the greatest selection of flight options on a Friday. Tuesdays are often the quietest.* However, this can vary depending on the airline, time of year and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Pounds Regional Airport (TYR) to Greenville-Spartanburg Intl. Airport (GSP)?
Opt for a flight from Pounds Regional Airport (TYR) to Greenville-Spartanburg Intl. Airport (GSP) that takes off before 3 PM to reduce the risk of cancellations. Later departures have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Pounds Regional Airport (TYR) to Greenville-Spartanburg Intl. Airport (GSP) last-minute?
Waiting until right before your break to book a ticket from TYR to GSP generally means paying more. While it's possible to find some last-minute deals, they're not always guaranteed. Keep your travel plans flexible for the best chance of landing a bargain.
Is it cheaper to book a TYR to GSP flight and hotel package?
You'll generally save money by booking a TYR to GSP flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's simple to manage it all in one convenient place. After choosing your preferred flights and accommodations, consider other add-ons like activities, car rentals and tours.
Can I cancel or change the date of my flight from Pounds Regional Airport (TYR) to Greenville-Spartanburg Intl. Airport (GSP)?
Typically, it's possible to cancel or reschedule your TYR to GSP flight. However, if the booking was made more than 24 hours ago, additional fees may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find more details on our Customer Service portal.

Travel information

Origin airport
Pounds Regional
Destination airport
Greenville-Spartanburg Intl.
Airlines serving
American Airlines
Roundtrip price
$458
Distance
778 mi

Book with confidence

Tyler to Greenville Flights

The cheapest times to fly from Tyler to Greenville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Tyler to Greenville are during the month of August. You can find some of the cheapest flights from Tyler to Greenville with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Tyler to Greenville

Sunday is one of the best days to book for cheap flights from Tyler to Greenville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Tyler to Greenville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Tyler to Greenville in 2025. You can also book with separate airlines for your outbound and return journeys, from $365 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Tyler to Greenville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Tyler to Greenville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Tyler to Greenville Flights

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*Available to One Key members.