Book luxury spa hotels in Santiago

Experience the ultimate relaxation at luxurious spa retreats in Santiago

Indulging in a luxury spa hotel in Santiago allows you to immerse yourself in a serene environment that harmoniously blends sophistication and tranquility. These high-end retreats offer rejuvenating spa treatments, exquisite dining options, and stunning views of the Andes Mountains. After a day of exploring the vibrant city or enjoying thrilling outdoor adventures like skiing, you can unwind in a lavish setting designed for relaxation and wellness. With a focus on comfort and pampering, luxury spa hotels provide a refreshing escape that will leave you feeling revitalized and ready for your next adventure.

Our top choices for a great stay

Santiago Marriott Hotel

Santiago Marriott Hotel

4.5 out of 5
$143 nightly
The price is $143 total per night from Dec 19 to Dec 20
$143 total
Dec 19 - Dec 20
Book a stay at this luxury hotel in Santiago. Enjoy an outdoor pool, 5 restaurants, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions Costanera Center and Parque Arauco Mall are located nearby.
8.6/10 Excellent! (432 reviews)
Opens in a new windowSantiago Marriott Hotel
Luciano K Hotel

Luciano K Hotel

4.5 out of 5
$136 nightly
The price is $136 total per night from Jan 3 to Jan 4
$136 total
Jan 3 - Jan 4, 2026
Book a stay at this luxury hotel in Santiago. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the breakfast and the bar in our reviews. Popular attractions Costanera Center and Parque Arauco Mall are located nearby.
8.8/10 Excellent! (680 reviews)
Opens in a new windowLuciano K Hotel
InterContinental Santiago by IHG

InterContinental Santiago by IHG

4.5 out of 5
$127 nightly
The price is $127 total per night from Dec 19 to Dec 20
$127 total
Dec 19 - Dec 20
Book a stay at this luxury hotel in Santiago. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Popular attractions Costanera Center and Parque Arauco Mall are located nearby.
7.8/10 Good! (341 reviews)
Opens in a new windowInterContinental Santiago by IHG
The Singular Santiago

The Singular Santiago

5 out of 5
$239 nightly
The price is $239 total per night from Dec 24 to Dec 25
$239 total
Dec 24 - Dec 25
Book a stay at this luxury hotel in Santiago. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the bar and the helpful staff in our reviews. Popular attractions Costanera Center and Parque Arauco Mall are located nearby.
9.4/10 Exceptional! (672 reviews)
Opens in a new windowThe Singular Santiago
Noi Vitacura

Noi Vitacura

5 out of 5
$196 nightly
The price is $196 total per night from Jan 1 to Jan 2
$196 total
Jan 1 - Jan 2, 2026
Book a stay at this luxury hotel in Santiago. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Costanera Center and Parque Arauco Mall are located nearby.
8.6/10 Excellent! (544 reviews)
Opens in a new windowNoi Vitacura
Regal Pacific Hotel Santiago

Regal Pacific Hotel Santiago

4.5 out of 5
Book a stay at this luxury hotel in Santiago. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Costanera Center and Parque Arauco Mall are located nearby.
9/10 Wonderful! (748 reviews)
Opens in a new windowRegal Pacific Hotel Santiago
Boulevard Suites Hotel

Boulevard Suites Hotel

4.5 out of 5
$150 nightly
The price is $150 total per night from Dec 21 to Dec 22
$150 total
Dec 21 - Dec 22
Book a stay at this luxury hotel in Santiago. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Costanera Center and Parque Arauco Mall are located nearby.
8.8/10 Excellent! (323 reviews)
Opens in a new windowBoulevard Suites Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Why choose luxury spa hotels in Santiago for your honeymoon or retreat?

For honeymooners or those seeking a peaceful retreat, opting for luxury spa hotels in Santiago can elevate your experience far beyond that of a standard hotel. These high-end spa getaways not only offer lavish accommodations but also provide a comprehensive wellness experience designed to rejuvenate both body and mind. Imagine indulging in soothing massages, refreshing facials, and calming aromatherapy sessions right at your doorstep. Unlike traditional hotels, luxury spa hotels focus on creating a holistic environment that encourages relaxation and connection, making it ideal for intimate escapes. The proximity to nature, combined with top-notch amenities, allows you to unwind in style while exploring Santiago’s rich culture, outdoor sports, or winter sports in nearby resorts. Choosing a wellness spa hotel means you can immerse yourself in tranquility, ensuring that your stay is as refreshing as it is memorable.