$139 Cheap American Airlines flights Harrisburg (MDT) to Houston (IAH)

Set the “Price (lowest to highest)” filter on Expedia to look for cheap American Airlines round-trip flights from $264 from MDT to IAH. Affordable one-way fares from $139 are available as well.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Look for one-way or return flights to Houston in November or February. You could find lower fares with American Airlines during these off-peak times.

For cheap American Airlines fares from Harrisburg Intl. Airport (MDT) to George Bush Intercontinental Airport (IAH), start searching one to three months before your planned departure. Securing domestic flights 34 to 86 days in advance could save you 25% compared to booking just 6 to 12 days ahead. The day you book can also affect what you pay. Sunday is usually the cheapest, while Monday is often the most expensive for domestic flights. You can save 6% on average by booking your journey on a Sunday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

Click on our “Nonstop” filter when searching for direct American Airlines flights from MDT to IAH. You’ll also be able to compare other carriers offering the same nonstop journey.

Search American Airlines’s earliest flights from MDT to IAH by using the “Early Morning” and “Morning” filters. Not only will you arrive sooner, early departures also experience 20% fewer cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

American Airlines flights from Harrisburg Intl. Airport (MDT) to Houston come in to land at George Bush Intercontinental Airport (IAH). This is the main entry point to this city.

Depending on the ticket type you purchased, a fee generally applies if you modify or cancel your booking more than 24 hours after it’s been confirmed. To secure flexible plane tickets, select our “No cancel fee” or “Changes included” filter when searching for flights. For additional information on canceling or changing your reservation, go to “Trips,” select your flight and tick “Manage Booking.”