$105 Cheap American Airlines flights Cleveland (CLE) to Harlingen (HRL)

Landing cheap one-way American Airlines flights from CLE to HRL from $105 on Expedia is easy — just filter by "Price (lowest to highest)." Alternatively, check out our affordable return fares from $230 for your next getaway.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Start searching one to three months before your departure to get cheap fares on American Airlines flights from Hopkins Intl. Airport (CLE) to Valley Intl. Airport (HRL). You can save 25% by booking your domestic flight 34 to 86 days in advance compared to last-minute reservations made 6 to 12 days out. You could also cut costs by buying your fare on a Sunday, as it's 6% cheaper on average than a Monday, the most expensive day to book.* Nail your timing, and you can enjoy significant savings on domestic journeys.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Filter your results by "Early Morning" and "Morning" to browse the earliest flights from CLE to HRL. Taking off early means you're less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.