$118 Cheap American Airlines flights Chicago (ORD) to San Antonio (SAT)

Scoring cheap one-way American Airlines flights from ORD to SAT from $118 on Expedia couldn't be simpler — just filter by "Price (lowest to highest)." Alternatively, check out our budget-friendly return fares from $235 for your next exciting vacation.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Begin your search one to three months ahead of your departure date to score cheap fares on American Airlines flights from O'Hare Intl. Airport (ORD) to San Antonio Intl. Airport (SAT). You can save 25% by booking your domestic flight 34 to 86 days in advance compared to last-minute reservations made 6 to 12 days out. You could also cut costs by buying your fare on a Sunday, as it's 6% cheaper on average than a Monday, the most expensive day to book.* Time it well, and you can enjoy significant savings on domestic flights.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

The first flight from ORD to SAT with American Airlines departs at 9:55AM UTC-6. You'll touch down at 1:01PM UTC-6. The final American Airlines flight of the day takes off at 8:45PM UTC-6 and arrives at 11:51PM UTC-6. With approximately 20% fewer cancellations for early and mid-morning flights, jetting out early is usually the best option.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.