$107 Cheap American Airlines flights San Francisco (SFO) to Charlotte (CLT)

Finding cheap one-way American Airlines flights from SFO to CLT from $107 on Expedia is simple — just filter by "Price (lowest to highest)." Alternatively, check out our budget-friendly round-trip fares from $181 for your next adventure.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

For cheap American Airlines fares from San Francisco Intl. Airport (SFO) to Charlotte-Douglas Intl. Airport (CLT), start searching one to three months before your planned departure. Reserving domestic flights 34 to 86 days in advance could save you 25% compared to booking just 6 to 12 days ahead. The day you book can also impact what you pay. Sunday tends to be the most affordable, while Monday is often the most expensive for domestic flights. You can save 6% on average by booking your trip on a Sunday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

The earliest flight from SFO to CLT with American Airlines leaves at 12:27AM UTC-8. You'll land at 8:25AM UTC-5. The last American Airlines flight of the day leaves at 1:51PM UTC-8 and arrives at 9:52PM UTC-5. With around 20% fewer cancellations for early and mid-morning departures, starting your travel day early is usually the best option.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.