$126 Cheap Delta flights Des Moines (DSM) to Greenville (GSP)

You can find affordable return Delta Air Lines flights from $236 from DSM to GSP by filtering your results from “Price (lowest to highest)” on Expedia. Or search for deals from $126 for a one-way trip.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Browse for one-way or round-trip flights to Greenville in January or December. You could find cheaper fares with Delta Air Lines during these off-peak travel months.

For cheap Delta Air Lines fares from Des Moines Intl. Airport (DSM) to Greenville-Spartanburg Intl. Airport (GSP), start searching one to three months before your intended departure. Reserving domestic flights 34 to 86 days in advance could save you 25% compared to booking just 6 to 12 days ahead. The day you book can also affect the price you pay. Sunday tends to be the cheapest, while Monday is often the most expensive for domestic flights. You can save 6% on average by booking your journey on a Sunday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

Use our “Nonstop” filter when looking for direct Delta Air Lines flights from DSM to GSP. You can also compare other carriers servicing the same nonstop trip.

Sort your results by “Early Morning” and “Morning” to see the earliest flights from DSM to GSP. Setting off early means flight cancellations are less likely.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

Greenville-Spartanburg Intl. Airport (GSP) is the main Greenville gateway for Delta Air Lines flights from Des Moines Intl. Airport (DSM).

Offering a rewarding loyalty program and an excellent in-flight experience, Delta Air Lines is the leading choice for many travelers flying from DSM to GSP. What’s more, if you’re a Delta SkyMiles and One Key™ member booking with Expedia, you could earn OneKeyCash™* on eligible flights on top of your airline miles, which you can put toward future travel.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.

You can usually cancel or modify your flight, although there may be additional fees if you made your booking more than 24 hours ago. Need flexible options? Use Expedia’s “Changes included” and “No cancel fee” filters to find flights that won’t penalize you if you have to alter your plans. To make modifications, head to “Trips,” select your flight and click on “Manage Booking” for further information.