$108 Cheap Delta flights Chicago (ORD) to Greenville (GSP)

Scoring cheap one-way Delta Air Lines flights from ORD to GSP from $108 on Expedia is simple — just filter by “Price (lowest to highest).” Or check out our budget-friendly return fares from $215 for your next adventure.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

January is one of the most affordable months to jet away to Greenville with Delta Air Lines. You could also find great prices on one-way and round-trip fares in December.

Begin your search one to three months ahead of your departure date to score cheap fares on Delta Air Lines flights from O’Hare Intl. Airport (ORD) to Greenville-Spartanburg Intl. Airport (GSP). You can save 25% by booking your domestic flight 34 to 86 days in advance versus last-minute reservations made 6 to 12 days out. You could also reduce costs by buying your fare on a Sunday, as it’s 6% cheaper on average than a Monday, the most expensive day to book.* Get your timing spot on, and you can enjoy significant savings on domestic trips.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

Enter your dates, click search and check the “Nonstop” filter on Expedia to browse any direct flights from ORD to GSP with Delta Air Lines or another airline.

To find the earliest departures from ORD to GSP with Delta Air Lines, sort your results by “Morning” and “Early Morning.” Choosing an early flight generally means cancellations are less likely.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

Jump on a Delta Air Lines flight from O’Hare Intl. Airport (ORD) to Greenville, and you’re most likely to come in to Greenville-Spartanburg Intl. Airport (GSP). This is the airline’s main hub here.

Delta Air Lines makes flying from ORD to GSP more enjoyable with a rewarding loyalty program and an excellent in-flight experience. You could even start collecting points with Delta SkyMiles. Don’t forget to join our free One Key™ rewards program to earn OneKeyCash™*, which can be redeemed on future trips.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.

Changes are typically free within 24 hours of booking, but your airline may charge you after that. For further details about altering your flights, go to your “Trips,” select your flight and click on “Manage Booking.” If you want the flexibility to change your itinerary without additional costs, apply the “No cancel fee” or “Changes included” filter when planning your next getaway.