$253 Cheap Flights from Lafayette (LFT) to Panama City (PTY)

View $253 flight on Tue, Nov 4, 2025Opens in a new window

Popular airlines from Lafayette Regional Airport (LFT) to Tocumen Intl. Airport (PTY)

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Cheap Flights from Lafayette to Panama City (LFT-PTY)

Prices were available within the past 7 days and start at $253 for one-way flights and $531 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Mon, Oct 6 - Wed, Oct 15
LFT
Lafayette
PTY
Panama City
$531 Roundtrip, found 3 days ago
$531
Roundtrip
found 3 days ago
Select Delta flight, departing Mon, Oct 6 from Lafayette to Panama City, returning Wed, Oct 15, priced at $531 found 3 days ago
United
Tue, Nov 4 - Mon, Nov 10
LFT
Lafayette
PTY
Panama City
$531 Roundtrip, found 1 day ago
$531
Roundtrip
found 1 day ago
Select United flight, departing Tue, Nov 4 from Lafayette to Panama City, returning Mon, Nov 10, priced at $531 found 1 day ago
American Airlines
Thu, Oct 9 - Mon, Oct 13
LFT
Lafayette
PTY
Panama City
$556 Roundtrip, found 3 days ago
$556
Roundtrip
found 3 days ago
Select American Airlines flight, departing Thu, Oct 9 from Lafayette to Panama City, returning Mon, Oct 13, priced at $556 found 3 days ago
United
Mon, Sep 15 - Mon, Dec 15
LFT
Lafayette
PTY
Panama City
$558 Roundtrip, found 6 days ago
$558
Roundtrip
found 6 days ago
Select United flight, departing Mon, Sep 15 from Lafayette to Panama City, returning Mon, Dec 15, priced at $558 found 6 days ago
United
Thu, Oct 9 - Mon, Oct 13
LFT
Lafayette
PTY
Panama City
$565 Roundtrip, found 3 days ago
$565
Roundtrip
found 3 days ago
Select United flight, departing Thu, Oct 9 from Lafayette to Panama City, returning Mon, Oct 13, priced at $565 found 3 days ago
United
Fri, Oct 10 - Sun, Oct 12
LFT
Lafayette
PTY
Panama City
$571 Roundtrip, found 3 days ago
$571
Roundtrip
found 3 days ago
Select United flight, departing Fri, Oct 10 from Lafayette to Panama City, returning Sun, Oct 12, priced at $571 found 3 days ago
American Airlines
Tue, Nov 4 - Mon, Nov 10
LFT
Lafayette
PTY
Panama City
$575 Roundtrip, found 5 hours ago
$575
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Tue, Nov 4 from Lafayette to Panama City, returning Mon, Nov 10, priced at $575 found 5 hours ago
United
Wed, Sep 10 - Thu, Sep 11
LFT
Lafayette
PTY
Panama City
$578 Roundtrip, found 6 days ago
$578
Roundtrip
found 6 days ago
Select United flight, departing Wed, Sep 10 from Lafayette to Panama City, returning Thu, Sep 11, priced at $578 found 6 days ago
Delta
Tue, Nov 4 - Mon, Nov 10
LFT
Lafayette
PTY
Panama City
$580 Roundtrip, found 5 hours ago
$580
Roundtrip
found 5 hours ago
Select Delta flight, departing Tue, Nov 4 from Lafayette to Panama City, returning Mon, Nov 10, priced at $580 found 5 hours ago
Delta
Tue, Nov 4 - Mon, Nov 10
LFT
Lafayette
PTY
Panama City
$589 Roundtrip, found 5 hours ago
$589
Roundtrip
found 5 hours ago
Select Delta flight, departing Tue, Nov 4 from Lafayette to Panama City, returning Mon, Nov 10, priced at $589 found 5 hours ago

Alternative airports near Panama City

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Tocumen Intl. PTY. Cheapest option available. Average driving time to city center is 16 minutes. Flights from $611
PTY
Tocumen Intl.
Cheapest
Average driving time to city center16 min
Flights from $611
Flights from Lafayette (LFT) to Panama City (PTY)
Origin airport
Lafayette Regional
Destination airport
Tocumen Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$531
Distance
1671 mi

Lafayette to Panama City Flights

The cheapest times to fly from Lafayette to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Lafayette to Panama City are during the month of October. You can find some of the cheapest flights from Lafayette to Panama City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Lafayette to Panama City

Sunday is one of the best days to book for cheap flights from Lafayette to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Lafayette to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Lafayette to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from $253 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Lafayette to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Lafayette to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Lafayette Regional Airport (LFT) to Tocumen Intl. Airport (PTY) cost?
Get a cheap one-way flight from $253 or cheap return flight from $531 from Lafayette Regional Airport (LFT) to Tocumen Intl. Airport (PTY) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Lafayette Regional Airport (LFT) to Tocumen Intl. Airport (PTY)?
October is the most affordable month to fly from LFT to PTY. Planning your trip for the off-season is often the key to finding better fares.
What is the cheapest airline that flies from Lafayette Regional Airport (LFT) to Tocumen Intl. Airport (PTY)?
Expedia's filter tool lets you easily compare different airlines, departure times and fares all in one place. Choose your preferences, then sort by "Price (lowest to highest)" to find the carrier with the cheapest LFT to PTY flight.
How many flights per day from Lafayette Regional Airport (LFT) to Tocumen Intl. Airport (PTY)?
Nonstop flights from Lafayette Regional Airport (LFT) to Tocumen Intl. Airport (PTY) aren't available daily, so you'll need to take a flight with a layover. Explore your options with our filter tool. Enter your travel details and choose either "1 Stop" or "2+ Stops."
What day of the week has the most flights from LFT to PTY?
Friday is usually the busiest day for flights, while Tuesday tends to be the quietest.* Just remember that flight schedules can vary depending on a range of factors, including the time of year and carrier.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Lafayette Regional Airport (LFT) to Tocumen Intl. Airport (PTY)?
To avoid potential delays on the Lafayette Regional Airport (LFT) to Tocumen Intl. Airport (PTY) route, travel before 3 PM. Later departures have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Lafayette Regional Airport (LFT) to Tocumen Intl. Airport (PTY) last-minute?
Booking your flight from LFT to PTY shortly before your journey is generally more expensive. However, if you're flexible with your schedule, you could bag a cheap last-minute fare.
Is it cheaper to book a LFT to PTY flight and hotel package?
Securing a LFT to PTY flight and hotel package is typically cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Choose from our wide range of stays and then add car rentals, flights and activities to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Lafayette Regional Airport (LFT) to Tocumen Intl. Airport (PTY)?
It's generally possible to cancel or reschedule your LFT to PTY flight. However, if it's been more than 24 hours since booking, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are possible and whether any costs are involved. You'll also find more details on our Customer Service portal.

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*Available to One Key members.