$182 Cheap Flights from Buffalo (BUF) to Medellín (MDE)

View $182 flight on Fri, Nov 14, 2025Opens in a new window

Popular airlines from Buffalo Niagara Intl. Airport (BUF) to Jose Maria Cordova Intl. Airport (MDE)

Cheap Flights from Buffalo to Medellín (BUF-MDE)

Prices were available within the past 7 days and start at $182 for one-way flights and $401 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

JetBlue Airways
Tue, Oct 28 - Fri, Nov 7
BUF
Buffalo
MDE
Medellin
$401 Roundtrip, found 1 day ago
$401
Roundtrip
found 1 day ago
Select JetBlue Airways flight, departing Tue, Oct 28 from Buffalo to Medellin, returning Fri, Nov 7, priced at $401 found 1 day ago
JetBlue Airways
Tue, Oct 28 - Fri, Nov 21
BUF
Buffalo
MDE
Medellin
$407 Roundtrip, found 2 days ago
$407
Roundtrip
found 2 days ago
Select JetBlue Airways flight, departing Tue, Oct 28 from Buffalo to Medellin, returning Fri, Nov 21, priced at $407 found 2 days ago
JetBlue Airways
Tue, Oct 28 - Sat, Nov 22
BUF
Buffalo
MDE
Medellin
$417 Roundtrip, found 2 days ago
$417
Roundtrip
found 2 days ago
Select JetBlue Airways flight, departing Tue, Oct 28 from Buffalo to Medellin, returning Sat, Nov 22, priced at $417 found 2 days ago
JetBlue Airways
Tue, Nov 18 - Fri, Nov 21
BUF
Buffalo
MDE
Medellin
$426 Roundtrip, found 2 days ago
$426
Roundtrip
found 2 days ago
Select JetBlue Airways flight, departing Tue, Nov 18 from Buffalo to Medellin, returning Fri, Nov 21, priced at $426 found 2 days ago
JetBlue Airways
Mon, Oct 27 - Fri, Nov 21
BUF
Buffalo
MDE
Medellin
$435 Roundtrip, found 2 days ago
$435
Roundtrip
found 2 days ago
Select JetBlue Airways flight, departing Mon, Oct 27 from Buffalo to Medellin, returning Fri, Nov 21, priced at $435 found 2 days ago
JetBlue Airways
Sat, Nov 15 - Thu, Nov 20
BUF
Buffalo
MDE
Medellin
$437 Roundtrip, found 2 days ago
$437
Roundtrip
found 2 days ago
Select JetBlue Airways flight, departing Sat, Nov 15 from Buffalo to Medellin, returning Thu, Nov 20, priced at $437 found 2 days ago
American Airlines
Sat, Feb 21 - Wed, Feb 25
BUF
Buffalo
MDE
Medellin
$565 Roundtrip, found 2 days ago
$565
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, Feb 21 from Buffalo to Medellin, returning Wed, Feb 25, priced at $565 found 2 days ago
United
Sat, Oct 25 - Wed, Nov 12
BUF
Buffalo
MDE
Medellin
$565 Roundtrip, found 1 day ago
$565
Roundtrip
found 1 day ago
Select United flight, departing Sat, Oct 25 from Buffalo to Medellin, returning Wed, Nov 12, priced at $565 found 1 day ago
Delta
Thu, Oct 30 - Tue, Nov 18
BUF
Buffalo
MDE
Medellin
$573 Roundtrip, found 2 days ago
$573
Roundtrip
found 2 days ago
Select Delta flight, departing Thu, Oct 30 from Buffalo to Medellin, returning Tue, Nov 18, priced at $573 found 2 days ago
LATAM Airlines Group
Sat, Oct 25 - Sun, Oct 26
BUF
Buffalo
MDE
Medellin
$597 Roundtrip, found 4 days ago
$597
Roundtrip
found 4 days ago
Select LATAM Airlines Group flight, departing Sat, Oct 25 from Buffalo to Medellin, returning Sun, Oct 26, priced at $597 found 4 days ago

Find the cheapest month to fly from Buffalo (BUF) to Medellín (MDE)

August is typically the cheapest month to fly

From $389 - $808 per traveler.

Alternative airports near Medellín

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Jose Maria Cordova Intl. MDE. Cheapest option available. Average driving time to city center is 29 minutes. Flights from $709
MDE
Jose Maria Cordova Intl.
Cheapest
Average driving time to city center29 min
Flights from $709
Flights from Buffalo (BUF) to Medellín (MDE)
Origin airport
Buffalo Niagara Intl.
Destination airport
José María Córdova Intl.
Airlines serving
American Airlines, Copa, Delta, JetBlue Airways, LATAM Airlines Group, United, avianca
Roundtrip price
$400
Distance
2547 mi

Buffalo to Medellín Flights

The cheapest times to fly from Buffalo to Medellín

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Buffalo to Medellín are during the month of October. You can find some of the cheapest flights from Buffalo to Medellín with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Buffalo to Medellín

Sunday is one of the best days to book for cheap flights from Buffalo to Medellín: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Buffalo to Medellín

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Buffalo to Medellín in 2025. You can also book with separate airlines for your outbound and return journeys, from $182 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Buffalo to Medellín flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Buffalo to Medellín airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Buffalo Niagara Intl. Airport (BUF) to Jose Maria Cordova Intl. Airport (MDE) cost?
Lock in a cheap one-way flight from $182 or cheap return flight from $401 from Buffalo Niagara Intl. Airport (BUF) to Jose Maria Cordova Intl. Airport (MDE) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Buffalo Niagara Intl. Airport (BUF) to Jose Maria Cordova Intl. Airport (MDE)?
October is the least expensive month to fly from BUF to MDE. Traveling during quieter months is often the key to scoring lower fares.
What is the cheapest airline that flies from Buffalo Niagara Intl. Airport (BUF) to Jose Maria Cordova Intl. Airport (MDE)?
To find the cheapest airline flying from BUF to MDE, use Expedia's filter tool. Tailor your search based on your travel style, such as preferred carriers and ideal departure window. You can then sort your results by "Price (lowest to highest)" to see the cheapest fares upfront.
How many flights per day from Buffalo Niagara Intl. Airport (BUF) to Jose Maria Cordova Intl. Airport (MDE)?
Direct flights from Buffalo Niagara Intl. Airport (BUF) to Jose Maria Cordova Intl. Airport (MDE) aren't available daily, so you'll have to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your travel details and choose either "1 Stop" or "2+ Stops."
What day of the week has the most flights from BUF to MDE?
You'll typically find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can vary from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Buffalo Niagara Intl. Airport (BUF) to Jose Maria Cordova Intl. Airport (MDE)?
Opt for a flight from Buffalo Niagara Intl. Airport (BUF) to Jose Maria Cordova Intl. Airport (MDE) that takes off before 3 PM to reduce the likelihood of delays and cancellations. Later departures are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Buffalo Niagara Intl. Airport (BUF) to Jose Maria Cordova Intl. Airport (MDE) last-minute?
Waiting until just before your departure to book your flight from BUF to MDE often results in higher prices. While you may find some last-minute deals, they aren't always guaranteed. Be flexible with your itinerary to boost your chances of landing a bargain.
Is it cheaper to book a BUF to MDE flight and hotel package?
Opting for a BUF to MDE flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your trip all in one place. Pick from our wide range of hotels and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Buffalo Niagara Intl. Airport (BUF) to Jose Maria Cordova Intl. Airport (MDE)?
If you reserved your BUF to MDE flight in the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of fare you purchased, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you want more information.

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*Available to One Key members.