$117 Cheap Flights from Cleveland (CLE) to Greenville (GSP)
Popular airlines from Cleveland Hopkins International Airport (CLE) to Greenville-Spartanburg Intl. Airport (GSP)
American AirlinesAmerican Airlines
DeltaDelta
Southwest AirlinesSouthwest Airlines
UnitedUnited
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Cheap Flights from Cleveland to Greenville (CLE-GSP)
Alternative airports near Greenville
Prices were available within the past 7 days. Prices and availability are subject to change.
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Cleveland (CLE) to Greenville (GSP) at a glance
Travel from Cleveland (CLE) to Greenville (GSP) with a range of airlines on this domestic short-haul route. Discover options for flights from Cleveland that cater to various budgets and schedules, including both full-service and low-cost carriers. As you plan your visit to explore the sights and neighborhoods of Greenville, compare weekly flights to find the best itinerary for your travel needs. Get ready to experience all that Greenville has to offer!
- Fastest flight duration: around 2h 45m in-flight, plus roughly 1 hour layover with one stop
- Route distance: roughly 450 miles (725 km)
- Flights per week: around 11 departures on average
- Typical fares (one-way): economy tickets often range from $100–$355, depending on seasonality and how far ahead you book
Flights from Hopkins International Airport (CLE) to Greenville-Spartanburg International Airport (GSP)
Based on the latest traveler bookings, here are the top airlines favored for one-stop flights from Cleveland to Greenville. Many passengers opt for layovers at Charlotte-Douglas International Airport (CLT) with an average layover of about 1 hour and 15 minutes, Hartsfield-Jackson Atlanta International Airport (ATL) also around 1 hour and 15 minutes, and Baltimore Washington International Thurgood Marshall Airport (BWI) with a 1-hour layover. These choices allow you to customize your itinerary by balancing price, total travel time, and cabin class.
- American Airlines: This major carrier offers one-stop flights, with one-way ticket prices typically falling between $100 and $360. It operates around 43% of the departures for this route, featuring a flight duration of 2 hours and 45 minutes, totaling approximately 4 hours for the entire journey, including layover time.
- Delta: Another full-service airline providing one-stop services, Delta's one-way fares usually range from $100 to $340. It accounts for about 34% of the flights on this route, with an in-air time of 2 hours and 45 minutes, resulting in an overall travel duration of nearly 4 hours, factoring in any layovers.
- Southwest Airlines: As a budget-friendly option, Southwest Airlines also provides one-stop services, with one-way fares generally ranging from $100 to $335. It represents roughly 13% of the departures on this route, featuring an in-flight time of 2 hours and 45 minutes and a total travel time of around 4 hours, including layovers.
- United: This full-service airline offers one-stop travel options, with one-way fares typically ranging from $110 to $360. United makes up about 10% of the departures on this route, with an in-flight duration of 2 hours and 45 minutes, leading to an overall journey time of about 4 hours, including layover periods.
Travelers flying from Cleveland to Greenville can opt for an upgrade, as American Airlines provides first-class service on this route for a more comfortable journey.
Best time to fly from Cleveland (CLE) to Greenville (GSP)
The most popular months for travelers flying from Cleveland to Greenville are February, March, and April, when peak temperatures in Greenville reach up to 59.9°F in April. If you prefer quieter travel, consider October, the least busy and relatively cheaper time to visit with fewer crowds and temperatures around 61.9°F. For better deals, September usually offers the lowest average one-way fare around $164. Flight availability peaks in April, with approximately 13 flights per week, making it easier to find convenient departure times. January has the fewest flights, with approximately 9 flights per week.
- Cheapest time to fly: September usually offers good deals with average one-way fare around $164, roughly 21% cheaper than the yearly average.
- Another budget-friendly time to fly: August typically offers an average one-way fare of around $172.
- Most flight options: April has the highest number of flights from Cleveland to Greenville, with approximately 13 flights per week, giving you more flexibility in scheduling your trip.
| Month | Temperature | Demand | Weekly Flights | Average one-way Fare |
| January | 41.4°F (5.2°C) | Average | 9 | $210 |
| February | 45.3°F (7.4°C) | High | 10 | $211 |
| March | 51.8°F (11.0°C) | High | 10 | $235 |
| April | 59.9°F (15.5°C) | High | 13 | $206 |
| May | 68.4°F (20.2°C) | Average | 12 | $196 |
| June | 76.1°F (24.5°C) | Average | 11 | $228 |
| July | 79.5°F (26.4°C) | Average | 12 | $192 |
| August | 77.5°F (25.3°C) | Average | 11 | $172 |
| September | 72.3°F (22.4°C) | Average | 12 | $164 |
| October | 61.9°F (16.6°C) | Low | 12 | $203 |
| November | 51.1°F (10.6°C) | Low | 11 | $273 |
| December | 45.3°F (7.4°C) | Low | 11 | $216 |
*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.
Alternative route from Cleveland (CLE) to Greenville (GSP)
- Akron to Greenville (CAK-GSP): Akron-Canton Airport (CAK) is located approximately 40 miles from Hopkins International Airport (CLE). One-way economy prices on this route generally fall between $115 and $415, varying by season and how early you make your reservation. Typically, travelers will find one-stop flights available, with common layover points at Charlotte-Douglas International Airport (CLT) and Ronald Reagan Washington National Airport (DCA). The leading airlines on this route include American Airlines and United, with first class also offered for those seeking a premium experience.
How to find the best prices for flights from Cleveland (CLE) to Greenville (GSP)
Getting some of the best deals on flights from Cleveland to Greenville is all about timing and flexibility. Here are some key tips to help you save:
- Best times to book and fly: cheaper fares are usually found when booking at least two months in advance, although most travelers tend to book between two to eight weeks ahead. Afternoon departures from 12 PM to 6 PM often offer lower prices, while morning flights from 5 AM to 12 PM are the most popular. Additionally, flying on Saturday generally results in cheaper prices, while Friday remains the busiest travel day.
- Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
- Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.* Find Greenville hotel and flight deals.
- Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
- Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
- Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.
*Members only. Savings vary and are not available on all bundles. Select hotels.
Arriving at Greenville-Spartanburg International Airport from Hopkins International Airport
Greenville welcomes travelers from Cleveland with a range of transport options based on price, convenience, and proximity. Greenville city center is approximately a 20-minute drive (covering about 16 miles) from Greenville-Spartanburg International Airport, depending on traffic. Here's how to reach Greenville efficiently:
- Hotel transfer: Transfers offer a convenient way to reach your hotel in Greenville, with options including free hotel shuttles and private rides, which can be arranged in advance with your hotel.
- Car rental: Renting a car from Greenville-Spartanburg International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Greenville-Spartanburg International Airport on Expedia.
- Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.
Cleveland to Greenville Flights
The cheapest times to fly from Cleveland to Greenville
On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Cleveland to Greenville are during the month of November. You can find some of the cheapest flights from Cleveland to Greenville with Expedia's search tool and vast selection of airlines.
The best time to book a flight from Cleveland to Greenville
Sunday is one of the best days to book for cheap flights from Cleveland to Greenville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.
How to find cheap round-trip tickets from Cleveland to Greenville
Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Cleveland to Greenville in 2026. You can also book with separate airlines for your outbound and return journeys, from $117 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.
Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Cleveland to Greenville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.
You could also save big by booking one of Expedia's vacation packages. Bundling together your Cleveland to Greenville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.
*Terms apply.
Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.
Frequently Asked Questions
How much does a flight from Cleveland, OH (CLE-Hopkins Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) cost?
You can find cheap one-way flights from $117 and cheap return flights $233 Cleveland, OH (CLE-Hopkins Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) with Expedia. One-way flights generally range between $135 and $583, and roundtrip flights usually range from $315 to $1047. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Cleveland, OH (CLE-Hopkins Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) ticket fares go up or down.
*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Cleveland, OH (CLE-Hopkins Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
August is the cheapest month to fly from Cleveland to Greenville, with average return fares around $258. This price is about 27% lower than the average throughout the year, as demand typically decreases after the summer travel season. Other budget-friendly months to consider are January and September.
*Averages based on flights available on Expedia in the last year.
Which airlines fly direct from Cleveland, OH (CLE-Hopkins Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
Enter CLE to GSP and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Cleveland, OH (CLE-Hopkins Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
Southwest Airlines is one of the cheapest airlines offering connecting flights from Hopkins Intl. (CLE) to Greenville-Spartanburg Intl. (GSP), with round-trip tickets starting from around $510 with a layover in Midway Intl. (MDW). Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.
*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Cleveland, OH (CLE-Hopkins Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
To find a cheap flight from Cleveland, OH (CLE-Hopkins Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Cleveland, OH (CLE-Hopkins Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
The best time to fly from Cleveland, OH (CLE) to Greenville, SC (GSP) is in August or September. Return flights during these months are around $258, making them the most affordable. August offers warm summer weather, while September provides a lovely transition into fall, enhancing your travel experience.
*Prices based on flights available on Expedia in the last year.
What is the earliest flight from Cleveland, OH (CLE-Hopkins Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
The earliest flight from Hopkins International Airport (CLE) to Greenville-Spartanburg International Airport (GSP) usually leaves at around 5:00 AM, also operated by American Airlines. This flight is part of a seasonal service active in December, giving you a great opportunity to make the most of your day in Greenville. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Cleveland, OH (CLE-Hopkins Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
For flights from Cleveland (CLE) to Greenville (GSP), the most popular departure times are also in the early morning, from 6am to 9am. This time window accounts for about 30% of passengers. Many major carriers, including American Airlines, Delta, and United, provide flights during this period. Many travelers prefer this timing as it helps them maximize their day upon arrival.
How long does it take to fly from Cleveland, OH (CLE-Hopkins Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
A flight from CLE to GSP with a layover takes around 5 hours, with the route covering approximately 451 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Cleveland, OH (CLE-Hopkins Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
First class is available on flights from CLE to GSP. First class cabins are available on:
- American Airlines
- Delta Air Lines
- United Airlines
How do I earn miles on a Cleveland, OH (CLE-Hopkins Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight with Expedia?
It's easy to earn miles on a Cleveland, OH (CLE-Hopkins Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.
*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Greenville from Hopkins Intl. (CLE)?
From Hopkins Intl. (CLE), you can fly into Pitt-Greenville (PGV), Mid Delta Regional (GLH) and Greenville-Spartanburg Intl. (GSP) in Greenville. Some flights may connect through major hubs like Philadelphia Intl. (PHL), Ronald Reagan Washington National (DCA), LaGuardia (LGA) before reaching Greenville. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Cleveland, OH (CLE-Hopkins Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) at the last minute?
Typically, booking a last minute flight from Cleveland, OH (CLE-Hopkins Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Cleveland, OH (CLE-Hopkins Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight and hotel package?
Securing a Cleveland, OH (CLE-Hopkins Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Cleveland, OH (CLE-Hopkins Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
If you booked your Cleveland, OH (CLE-Hopkins Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.
Travel information
Origin airport | Cleveland Hopkins International Airport |
|---|---|
Destination airport | Greenville-Spartanburg Intl. Airport |
Distance | 450 miles away |
Airlines serving | American Airlines, Delta, Southwest Airlines, United |
Popular airline | American Airlines |
Roundtrip price | $233 |