$40 Cheap Flights from Cali (CLO) to Medellín (MDE)

View $40 flight on Wed, Nov 5, 2025Opens in a new window

Popular airlines from Alfonso Bonilla Aragon Intl. Airport (CLO) to Jose Maria Cordova Intl. Airport (MDE)

Cheap Flights from Cali to Medellín (CLO-MDE)

Prices were available within the past 7 days and start at $40 for one-way flights and $79 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Jetsmart SPA
Thu, Nov 6 - Mon, Nov 10
CLO
Cali
MDE
Medellin
$79 Roundtrip, found 2 hours ago
$79
Roundtrip
found 2 hours ago
Select Jetsmart SPA flight, departing Thu, Nov 6 from Cali to Medellin, returning Mon, Nov 10, priced at $79 found 2 hours ago
Jetsmart SPA
Fri, Nov 21 - Tue, Nov 25
CLO
Cali
MDE
Medellin
$83 Roundtrip, found 1 hour ago
$83
Roundtrip
found 1 hour ago
Select Jetsmart SPA flight, departing Fri, Nov 21 from Cali to Medellin, returning Tue, Nov 25, priced at $83 found 1 hour ago
Jetsmart SPA
Sun, Sep 21 - Fri, Sep 26
CLO
Cali
MDE
Medellin
$83 Roundtrip, found 5 days ago
$83
Roundtrip
found 5 days ago
Select Jetsmart SPA flight, departing Sun, Sep 21 from Cali to Medellin, returning Fri, Sep 26, priced at $83 found 5 days ago
Jetsmart SPA
Sat, Nov 15 - Sun, Nov 16
CLO
Cali
MDE
Medellin
$86 Roundtrip, found 1 day ago
$86
Roundtrip
found 1 day ago
Select Jetsmart SPA flight, departing Sat, Nov 15 from Cali to Medellin, returning Sun, Nov 16, priced at $86 found 1 day ago
Jetsmart SPA
Sat, Oct 11 - Mon, Oct 13
CLO
Cali
MDE
Medellin
$87 Roundtrip, found 1 day ago
$87
Roundtrip
found 1 day ago
Select Jetsmart SPA flight, departing Sat, Oct 11 from Cali to Medellin, returning Mon, Oct 13, priced at $87 found 1 day ago
Jetsmart SPA
Wed, Sep 24 - Mon, Sep 29
CLO
Cali
MDE
Medellin
$88 Roundtrip, found 3 hours ago
$88
Roundtrip
found 3 hours ago
Select Jetsmart SPA flight, departing Wed, Sep 24 from Cali to Medellin, returning Mon, Sep 29, priced at $88 found 3 hours ago
Jetsmart SPA
Thu, Sep 18 - Wed, Sep 24
CLO
Cali
MDE
Medellin
$90 Roundtrip, found 2 hours ago
$90
Roundtrip
found 2 hours ago
Select Jetsmart SPA flight, departing Thu, Sep 18 from Cali to Medellin, returning Wed, Sep 24, priced at $90 found 2 hours ago
Jetsmart SPA
Fri, Nov 21 - Tue, Nov 25
CLO
Cali
MDE
Medellin
$91 Roundtrip, found 1 hour ago
$91
Roundtrip
found 1 hour ago
Select Jetsmart SPA flight, departing Fri, Nov 21 from Cali to Medellin, returning Tue, Nov 25, priced at $91 found 1 hour ago
LATAM Airlines Group
Fri, Oct 3 - Mon, Oct 6
CLO
Cali
MDE
Medellin
$103 Roundtrip, found 6 hours ago
$103
Roundtrip
found 6 hours ago
Select LATAM Airlines Group flight, departing Fri, Oct 3 from Cali to Medellin, returning Mon, Oct 6, priced at $103 found 6 hours ago
avianca
Wed, Jan 28 - Sun, Feb 1
CLO
Cali
MDE
Medellin
$164 Roundtrip, found 5 days ago
$164
Roundtrip
found 5 days ago
Select avianca flight, departing Wed, Jan 28 from Cali to Medellin, returning Sun, Feb 1, priced at $164 found 5 days ago

Find the cheapest month to fly from Cali (CLO) to Medellín (MDE)

May is typically the cheapest month to fly

From $60 - $148 per traveler.

Alternative airports near Medellín

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Enrique Olaya Herrera EOH. Closest option available. Average driving time to city center is 4 minutes. Flights from $338
EOH
Enrique Olaya Herrera
Closest
Average driving time to city center4 min
Flights from $338
0
Flights from Cali (CLO) to Medellín (MDE)
Origin airport
Alfonso Bonilla Aragon Intl.
Destination airport
José María Córdova Intl.
Airlines serving
Jetsmart SPA, LATAM Airlines Group, avianca
Roundtrip price
$78
Distance
193 mi

Cali to Medellín Flights

The cheapest times to fly from Cali to Medellín

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Cali to Medellín are during the month of November. You can find some of the cheapest flights from Cali to Medellín with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Cali to Medellín

Sunday is one of the best days to book for cheap flights from Cali to Medellín: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Cali to Medellín

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Cali to Medellín in 2025. You can also book with separate airlines for your outbound and return journeys, from $40 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Cali to Medellín flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Cali to Medellín airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Alfonso Bonilla Aragon Intl. Airport (CLO) to Jose Maria Cordova Intl. Airport (MDE) cost?
Get a cheap one-way flight from $40 or cheap return flight from $79 from Alfonso Bonilla Aragon Intl. Airport (CLO) to Jose Maria Cordova Intl. Airport (MDE) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Alfonso Bonilla Aragon Intl. Airport (CLO) to Jose Maria Cordova Intl. Airport (MDE)?
The cheapest month to fly from CLO to MDE is November, when there's less demand. Off-peak season is usually when you'll find lower airfares between these airports.
Which airlines fly direct from Alfonso Bonilla Aragon Intl. Airport (CLO) to Jose Maria Cordova Intl. Airport (MDE)?
Take your pick of 3 carriers that fly direct from Alfonso Bonilla Aragon Intl. Airport (CLO) to Jose Maria Cordova Intl. Airport (MDE). Including:

  • AVIANCA
  • LATAM Airlines
  • JetSMART

What is the cheapest airline that flies from Alfonso Bonilla Aragon Intl. Airport (CLO) to Jose Maria Cordova Intl. Airport (MDE)?
While prices may vary depending on when you travel, JetSMART and LATAM Airlines are go-to choices for flights between Alfonso Bonilla Aragon Intl. Airport (CLO) and Jose Maria Cordova Intl. Airport (MDE). You can also compare carriers on Expedia and use the "Sort by" filter to find the best deal for your CLO to MDE flight.
How many flights per day from Alfonso Bonilla Aragon Intl. Airport (CLO) to Jose Maria Cordova Intl. Airport (MDE)?
Daily, an average of 6 nonstop flights operate from Alfonso Bonilla Aragon Intl. Airport (CLO) to Jose Maria Cordova Intl. Airport (MDE). Choose the departure date that best fits your schedule.
What are the most popular departure times for flights from Alfonso Bonilla Aragon Intl. Airport (CLO) to Jose Maria Cordova Intl. Airport (MDE)?
More travelers fly between CLO and MDE at 6 AM than at any other point in the day. Prefer a quieter experience? Consider flying outside peak hours and you could save on your fare as well.
What day of the week has the most flights from CLO to MDE?
Depart on a Friday if you're after the best choice of flights from Alfonso Bonilla Aragon Intl. Airport (CLO) to Jose Maria Cordova Intl. Airport (MDE).
What is the earliest flight from Alfonso Bonilla Aragon Intl. Airport (CLO) to Jose Maria Cordova Intl. Airport (MDE)?
Alfonso Bonilla Aragon Intl. Airport (CLO)'s first flight to Jose Maria Cordova Intl. Airport (MDE) takes off at approximately 4:50AM UTC-5. With a travel duration of 53m, you'll arrive at around 5:43AM UTC-5.
How long does it take to fly from Alfonso Bonilla Aragon Intl. Airport (CLO) to Jose Maria Cordova Intl. Airport (MDE)?
The average flight time from CLO to MDE is 52 minutes, covering a distance of 190 mi.
What airline has the least delays from CLO to MDE?
With 83% of journeys typically landing on schedule, LATAM Airlines has the best on-time performance for nonstop flights from Alfonso Bonilla Aragon Intl. Airport (CLO) to Jose Maria Cordova Intl. Airport (MDE). To monitor your flight status and get notifications about any changes, head to the Expedia App.
What is the best time to fly from Alfonso Bonilla Aragon Intl. Airport (CLO) to Jose Maria Cordova Intl. Airport (MDE)?
To avoid potential delays on the Alfonso Bonilla Aragon Intl. Airport (CLO) to Jose Maria Cordova Intl. Airport (MDE) route, travel before 3 PM. Departures after this time have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Medellin from Alfonso Bonilla Aragon Intl. Airport (CLO)?
You can arrive at Jose Maria Cordova Intl. Airport (MDE) or Enrique Olaya Herrera Airport (EOH) when traveling to Medellin on a direct flight from Alfonso Bonilla Aragon Intl. Airport (CLO).
Is it cheaper to buy a plane ticket from Alfonso Bonilla Aragon Intl. Airport (CLO) to Jose Maria Cordova Intl. Airport (MDE) last-minute?
Holding off until right before your break to book a ticket from CLO to MDE generally means paying more. While you might find some last-minute discounts, they aren't always guaranteed. Keep your travel plans flexible to boost your chances of scoring a bargain.
Is it cheaper to book a CLO to MDE flight and hotel package?
Compared with arranging flights and hotels separately, booking a CLO to MDE flight and hotel package with Expedia could result in significant savings. Better yet, having it all in one place will take the stress out of planning your trip. Simply pick your flights and choose from our wide range of hotels, then customize your trip with other add-ons like tours and car rentals.
Can I cancel or change the date of my flight from Alfonso Bonilla Aragon Intl. Airport (CLO) to Jose Maria Cordova Intl. Airport (MDE)?
Typically, you can cancel or reschedule your CLO to MDE flight. However, additional fees may apply, especially if you made your booking over 24 hours ago. Double-check your itinerary for the airline's fees and rules on flight changes, or if you want further information, visit our Customer Service portal.

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*Available to One Key members.