$221 Cheap Flights from Charlotte (CLT) to Panama City (PTY)

View $221 flight on Thu, Apr 2, 2026Opens in a new window

Popular airlines from Charlotte-Douglas Intl. Airport (CLT) to Tocumen Intl. Airport (PTY)

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Cheap Flights from Charlotte to Panama City (CLT-PTY)

Prices were available within the past 7 days and start at $221 for one-way flights and $467 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Tue, Oct 28 - Wed, Oct 29
CLT
Charlotte
PTY
Panama City
$467 Roundtrip, found 2 hours ago
$467
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Tue, Oct 28 from Charlotte to Panama City, returning Wed, Oct 29, priced at $467 found 2 hours ago
Delta
Tue, Oct 28 - Wed, Oct 29
CLT
Charlotte
PTY
Panama City
$467 Roundtrip, found 2 hours ago
$467
Roundtrip
found 2 hours ago
Select Delta flight, departing Tue, Oct 28 from Charlotte to Panama City, returning Wed, Oct 29, priced at $467 found 2 hours ago
United
Wed, Oct 1 - Wed, Oct 8
CLT
Charlotte
PTY
Panama City
$467 Roundtrip, found 6 hours ago
$467
Roundtrip
found 6 hours ago
Select United flight, departing Wed, Oct 1 from Charlotte to Panama City, returning Wed, Oct 8, priced at $467 found 6 hours ago
American Airlines
Thu, Apr 2 - Thu, Apr 9
CLT
Charlotte
PTY
Panama City
$472 Roundtrip, just found
$472
Roundtrip
just found
Select American Airlines flight, departing Thu, Apr 2 from Charlotte to Panama City, returning Thu, Apr 9, priced at $472 just found
Delta
Sun, Oct 26 - Thu, Nov 6
CLT
Charlotte
PTY
Panama City
$474 Roundtrip, found 2 hours ago
$474
Roundtrip
found 2 hours ago
Select Delta flight, departing Sun, Oct 26 from Charlotte to Panama City, returning Thu, Nov 6, priced at $474 found 2 hours ago
United
Thu, Jan 22 - Mon, Jan 26
CLT
Charlotte
PTY
Panama City
$477 Roundtrip, found 1 day ago
$477
Roundtrip
found 1 day ago
Select United flight, departing Thu, Jan 22 from Charlotte to Panama City, returning Mon, Jan 26, priced at $477 found 1 day ago
Delta
Sun, Sep 14 - Tue, Sep 23
CLT
Charlotte
PTY
Panama City
$481 Roundtrip, found 6 hours ago
$481
Roundtrip
found 6 hours ago
Select Delta flight, departing Sun, Sep 14 from Charlotte to Panama City, returning Tue, Sep 23, priced at $481 found 6 hours ago
American Airlines
Mon, May 18 - Thu, May 28
CLT
Charlotte
PTY
Panama City
$481 Roundtrip, found 4 hours ago
$481
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Mon, May 18 from Charlotte to Panama City, returning Thu, May 28, priced at $481 found 4 hours ago
United
Wed, Apr 15 - Tue, Apr 21
CLT
Charlotte
PTY
Panama City
$484 Roundtrip, found 1 day ago
$484
Roundtrip
found 1 day ago
Select United flight, departing Wed, Apr 15 from Charlotte to Panama City, returning Tue, Apr 21, priced at $484 found 1 day ago
Copa
Fri, Jul 25 - Mon, Jul 28
CLT
Charlotte
PTY
Panama City
$727 Roundtrip, found 1 hour ago
$727
Roundtrip
found 1 hour ago
Select Copa flight, departing Fri, Jul 25 from Charlotte to Panama City, returning Mon, Jul 28, priced at $727 found 1 hour ago

Find the cheapest month to fly from Charlotte (CLT) to Panama City (PTY)

August is typically the cheapest month to fly

From $375 - $1,039 per traveler.

Graph displaying average flight prices per month

Flights from Charlotte (CLT) to Panama City (PTY)
Origin airport
Charlotte-Douglas Intl.
Destination airport
Tocumen Intl.
Airlines serving
American Airlines, Copa, Delta, United
Roundtrip price
$467
Distance
1809 mi

Charlotte to Panama City Flights

The cheapest times to fly from Charlotte to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Charlotte to Panama City are during the month of October. You can find some of the cheapest flights from Charlotte to Panama City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Charlotte to Panama City

Sunday is one of the best days to book for cheap flights from Charlotte to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Charlotte to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Charlotte to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from $221 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Charlotte to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Charlotte to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Charlotte-Douglas Intl. Airport (CLT) to Tocumen Intl. Airport (PTY) cost?
Discover the latest flight deals from CLT to PTY by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from CLT to PTY?
The cheapest flights from CLT to PTY are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from CLT to PTY?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll take you from CLT to PTY. Sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from Charlotte-Douglas Intl. Airport (CLT) to Tocumen Intl. Airport (PTY)?
There are no daily direct flights available from Charlotte-Douglas Intl. Airport (CLT) to Tocumen Intl. Airport (PTY). But you can opt for flights with layovers. Filter your search results on Expedia to include one or two stops, and you'll be on your way in no time at all.
What day of the week has the most flights from CLT to PTY?
Friday is typically the busiest day for flights, while Tuesday tends to be the quietest.* Remember that flight schedules can vary depending on a range of factors, such as the carrier and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Charlotte-Douglas Intl. Airport (CLT) to Tocumen Intl. Airport (PTY)?
Book a flight from Charlotte-Douglas Intl. Airport (CLT) to Tocumen Intl. Airport (PTY) that takes off before 3 PM to reduce the risk of cancellations. Departures after this hour are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Charlotte-Douglas Intl. Airport (CLT) to Tocumen Intl. Airport (PTY) last-minute?
Booking your ticket from CLT to PTY right before your journey is usually more expensive. But if there's some wiggle room with your travel times and dates, you could snag a cheap last-minute fare.
Is it cheaper to book a CLT to PTY flight and hotel package?
Compared with arranging flights and hotels separately, booking a CLT to PTY flight and hotel package with Expedia could lead to significant savings. Better yet, having it all in one place takes the hassle out of travel planning. Simply secure your flights and choose from our wide range of hotels, then customize your trip with extras like tours and car rentals.
Can I cancel or change the date of my flight from Charlotte-Douglas Intl. Airport (CLT) to Tocumen Intl. Airport (PTY)?
If you booked your CLT to PTY flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal if you want more information.

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*Available to One Key members.