$373 Cheap Flights from Des Moines (DSM) to Regina (YQR)

View $373 flight on Fri, Dec 26, 2025Opens in a new window

Popular airlines from Des Moines International Airport (DSM) to Regina Intl. Airport (YQR)

Cheap Flights from Des Moines to Regina (DSM-YQR)

Prices were available within the past 7 days and start at $373 for one-way flights and $651 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

WestJet
Tue, Dec 2 - Sun, Dec 7
DSM
Des Moines
YQR
Regina
$651 Roundtrip, found 6 days ago
$651
Roundtrip
found 6 days ago
Select WestJet flight, departing Tue, Dec 2 from Des Moines to Regina, returning Sun, Dec 7, priced at $651 found 6 days ago
United
Tue, Dec 2 - Sun, Dec 7
DSM
Des Moines
YQR
Regina
$681 Roundtrip, found 6 days ago
$681
Roundtrip
found 6 days ago
Select United flight, departing Tue, Dec 2 from Des Moines to Regina, returning Sun, Dec 7, priced at $681 found 6 days ago
United
Tue, Dec 2 - Sun, Dec 7
DSM
Des Moines
YQR
Regina
$708 Roundtrip, found 6 days ago
$708
Roundtrip
found 6 days ago
Select United flight, departing Tue, Dec 2 from Des Moines to Regina, returning Sun, Dec 7, priced at $708 found 6 days ago
United
Tue, Dec 2 - Sun, Dec 7
DSM
Des Moines
YQR
Regina
$712 Roundtrip, found 6 days ago
$712
Roundtrip
found 6 days ago
Select United flight, departing Tue, Dec 2 from Des Moines to Regina, returning Sun, Dec 7, priced at $712 found 6 days ago
United
Tue, Dec 2 - Sun, Dec 7
DSM
Des Moines
YQR
Regina
$738 Roundtrip, found 6 days ago
$738
Roundtrip
found 6 days ago
Select United flight, departing Tue, Dec 2 from Des Moines to Regina, returning Sun, Dec 7, priced at $738 found 6 days ago

Frequently asked questions

How much does a flight from Des Moines Intl. Airport (DSM) to Regina Intl. Airport (YQR) cost?
Get a cheap one-way flight from $373 or cheap return flight from $651 from Des Moines Intl. Airport (DSM) to Regina Intl. Airport (YQR) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Des Moines Intl. Airport (DSM) to Regina Intl. Airport (YQR)?
December is the most affordable month to fly from DSM to YQR. Traveling outside of peak seasons is often the key to scoring lower fares.
What is the cheapest airline that flies from Des Moines Intl. Airport (DSM) to Regina Intl. Airport (YQR)?
Use the filter tool on Expedia to compare airlines and find the most affordable carrier that'll fly you from DSM to YQR. Then, sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from Des Moines Intl. Airport (DSM) to Regina Intl. Airport (YQR)?
Direct flights from Des Moines Intl. Airport (DSM) to Regina Intl. Airport (YQR) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your dates and choose either "1 Stop" or "2+ Stops."
What day of the week has the most flights from DSM to YQR?
Friday is typically the busiest day for flights, while Tuesday is often the quietest.* Remember that flight schedules can vary based on various factors, including the time of year and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Des Moines Intl. Airport (DSM) to Regina Intl. Airport (YQR)?
To touch down at Regina Intl. Airport (YQR) on schedule, opt for a flight that takes off from Des Moines Intl. Airport (DSM) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Des Moines Intl. Airport (DSM) to Regina Intl. Airport (YQR) last-minute?
Booking your ticket from DSM to YQR just before your journey is typically more expensive. But if there's some wiggle room with your schedule, you could snag a cheap last-minute fare.
Is it cheaper to book a DSM to YQR flight and hotel package?
Opting for a DSM to YQR flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Pick from our wide range of hotels and then add flights, car rentals and activities to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Des Moines Intl. Airport (DSM) to Regina Intl. Airport (YQR)?
If you booked your DSM to YQR flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of fare you purchased, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal if you want more information.

Travel information

Origin airport
Des Moines Intl.
Destination airport
Regina Intl.
Roundtrip price
$651
Distance
809 mi

Book with confidence

Des Moines to Regina Flights

The cheapest times to fly from Des Moines to Regina

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Des Moines to Regina are during the month of December. You can find some of the cheapest flights from Des Moines to Regina with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Des Moines to Regina

Sunday is one of the best days to book for cheap flights from Des Moines to Regina: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Des Moines to Regina

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Des Moines to Regina in 2025. You can also book with separate airlines for your outbound and return journeys, from $373 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Des Moines to Regina flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Des Moines to Regina airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Des Moines to Regina Flights

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*Available to One Key members.