$291 Cheap Flights from Des Moines (DSM) to Regina (YQR)

View $291 flight on Fri, Sep 26, 2025Opens in a new window

Popular airlines from Des Moines International Airport (DSM) to Regina Intl. Airport (YQR)

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Cheap Flights from Des Moines to Regina (DSM-YQR)

Prices were available within the past 7 days and start at $291 for one-way flights and $568 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Fri, Sep 26 - Sat, Sep 27
DSM
Des Moines
YQR
Regina
$568 Roundtrip, found 10 hours ago
$568
Roundtrip
found 10 hours ago
Select Delta flight, departing Fri, Sep 26 from Des Moines to Regina, returning Sat, Sep 27, priced at $568 found 10 hours ago
WestJet
Fri, Sep 26 - Tue, Sep 30
DSM
Des Moines
YQR
Regina
$574 Roundtrip, found 10 hours ago
$574
Roundtrip
found 10 hours ago
Select WestJet flight, departing Fri, Sep 26 from Des Moines to Regina, returning Tue, Sep 30, priced at $574 found 10 hours ago
Delta
Wed, Sep 24 - Sat, Sep 27
DSM
Des Moines
YQR
Regina
$598 Roundtrip, found 10 hours ago
$598
Roundtrip
found 10 hours ago
Select Delta flight, departing Wed, Sep 24 from Des Moines to Regina, returning Sat, Sep 27, priced at $598 found 10 hours ago
United
Mon, Sep 29 - Sat, Oct 4
DSM
Des Moines
YQR
Regina
$624 Roundtrip, found 20 hours ago
$624
Roundtrip
found 20 hours ago
Select United flight, departing Mon, Sep 29 from Des Moines to Regina, returning Sat, Oct 4, priced at $624 found 20 hours ago
Delta
Wed, Sep 24 - Sun, Sep 28
DSM
Des Moines
YQR
Regina
$629 Roundtrip, found 10 hours ago
$629
Roundtrip
found 10 hours ago
Select Delta flight, departing Wed, Sep 24 from Des Moines to Regina, returning Sun, Sep 28, priced at $629 found 10 hours ago
WestJet
Mon, Sep 29 - Wed, Oct 1
DSM
Des Moines
YQR
Regina
$630 Roundtrip, found 10 hours ago
$630
Roundtrip
found 10 hours ago
Select WestJet flight, departing Mon, Sep 29 from Des Moines to Regina, returning Wed, Oct 1, priced at $630 found 10 hours ago
WestJet
Sun, Oct 12 - Fri, Oct 17
DSM
Des Moines
YQR
Regina
$635 Roundtrip, found 17 hours ago
$635
Roundtrip
found 17 hours ago
Select WestJet flight, departing Sun, Oct 12 from Des Moines to Regina, returning Fri, Oct 17, priced at $635 found 17 hours ago
WestJet
Tue, Oct 14 - Fri, Oct 17
DSM
Des Moines
YQR
Regina
$638 Roundtrip, found 2 days ago
$638
Roundtrip
found 2 days ago
Select WestJet flight, departing Tue, Oct 14 from Des Moines to Regina, returning Fri, Oct 17, priced at $638 found 2 days ago
WestJet
Mon, Sep 29 - Sat, Oct 4
DSM
Des Moines
YQR
Regina
$640 Roundtrip, found 20 hours ago
$640
Roundtrip
found 20 hours ago
Select WestJet flight, departing Mon, Sep 29 from Des Moines to Regina, returning Sat, Oct 4, priced at $640 found 20 hours ago
Air Canada
Sat, Sep 27 - Thu, Oct 2
DSM
Des Moines
YQR
Regina
$788 Roundtrip, found 20 hours ago
$788
Roundtrip
found 20 hours ago
Select Air Canada flight, departing Sat, Sep 27 from Des Moines to Regina, returning Thu, Oct 2, priced at $788 found 20 hours ago

Alternative airports near Regina

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Regina Intl. YQR. Cheapest and Closest option available. Average driving time to city center is 5 minutes. Flights from $843
YQR
Regina Intl.
CheapestClosest
Average driving time to city center5 min
Flights from $843
Flights from Des Moines (DSM) to Regina (YQR)
Origin airport
Des Moines Intl.
Destination airport
Regina Intl.
Airlines serving
Air Canada, United, WestJet
Roundtrip price
$568
Distance
809 mi

Des Moines to Regina Flights

The cheapest times to fly from Des Moines to Regina

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Des Moines to Regina are during the month of September. You can find some of the cheapest flights from Des Moines to Regina with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Des Moines to Regina

Sunday is one of the best days to book for cheap flights from Des Moines to Regina: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Des Moines to Regina

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Des Moines to Regina in 2025. You can also book with separate airlines for your outbound and return journeys, from $291 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Des Moines to Regina flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Des Moines to Regina airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Des Moines Intl. Airport (DSM) to Regina Intl. Airport (YQR) cost?
Get a cheap one-way flight from $291 or cheap return flight from $568 from Des Moines Intl. Airport (DSM) to Regina Intl. Airport (YQR) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Des Moines Intl. Airport (DSM) to Regina Intl. Airport (YQR)?
September is the most affordable month to fly from DSM to YQR. Traveling outside of peak seasons is often the key to scoring lower fares.
What is the cheapest airline that flies from Des Moines Intl. Airport (DSM) to Regina Intl. Airport (YQR)?
Use the filter tool on Expedia to compare airlines and find the most affordable carrier that'll fly you from DSM to YQR. Then, sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from Des Moines Intl. Airport (DSM) to Regina Intl. Airport (YQR)?
Direct flights from Des Moines Intl. Airport (DSM) to Regina Intl. Airport (YQR) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your dates and choose either "1 Stop" or "2+ Stops."
What day of the week has the most flights from DSM to YQR?
Friday is typically the busiest day for flights, while Tuesday is often the quietest.* Remember that flight schedules can vary based on various factors, including the time of year and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Des Moines Intl. Airport (DSM) to Regina Intl. Airport (YQR)?
To touch down at Regina Intl. Airport (YQR) on schedule, opt for a flight that takes off from Des Moines Intl. Airport (DSM) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Des Moines Intl. Airport (DSM) to Regina Intl. Airport (YQR) last-minute?
Booking your ticket from DSM to YQR just before your journey is typically more expensive. But if there's some wiggle room with your schedule, you could snag a cheap last-minute fare.
Is it cheaper to book a DSM to YQR flight and hotel package?
Opting for a DSM to YQR flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Pick from our wide range of hotels and then add flights, car rentals and activities to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Des Moines Intl. Airport (DSM) to Regina Intl. Airport (YQR)?
If you booked your DSM to YQR flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of fare you purchased, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal if you want more information.

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*Available to One Key members.