$123 Cheap Flights from Key West (EYW) to Charlotte (CLT)

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Popular airlines from Key West Intl. Airport (EYW) to Charlotte-Douglas Intl. Airport (CLT)

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Cheap Flights from Key West to Charlotte (EYW-CLT)

Prices were available within the past 7 days and start at $123 for one-way flights and $290 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Spirit Airlines
Thu, Jan 8 - Tue, Jan 13
EYW
Key West
CLT
Charlotte
$290 Roundtrip, found 3 days ago
$290
Roundtrip
found 3 days ago
Select Spirit Airlines flight, departing Thu, Jan 8 from Key West to Charlotte, returning Tue, Jan 13, priced at $290 found 3 days ago
American Airlines
Tue, Nov 18 - Thu, Nov 20
EYW
Key West
CLT
Charlotte
$358 Roundtrip, found 5 days ago
$358
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, Nov 18 from Key West to Charlotte, returning Thu, Nov 20, priced at $358 found 5 days ago
American Airlines
Tue, Nov 18 - Thu, Nov 20
EYW
Key West
CLT
Charlotte
$360 Roundtrip, found 5 days ago
$360
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, Nov 18 from Key West to Charlotte, returning Thu, Nov 20, priced at $360 found 5 days ago
American Airlines
Sat, Dec 13 - Tue, Dec 16
EYW
Key West
CLT
Charlotte
$402 Roundtrip, found 5 days ago
$402
Roundtrip
found 5 days ago
Select American Airlines flight, departing Sat, Dec 13 from Key West to Charlotte, returning Tue, Dec 16, priced at $402 found 5 days ago
American Airlines
Tue, Nov 18 - Thu, Nov 20
EYW
Key West
CLT
Charlotte
$423 Roundtrip, found 5 days ago
$423
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, Nov 18 from Key West to Charlotte, returning Thu, Nov 20, priced at $423 found 5 days ago
Delta
Tue, Oct 21 - Tue, Oct 28
EYW
Key West
CLT
Charlotte
$428 Roundtrip, found 5 days ago
$428
Roundtrip
found 5 days ago
Select Delta flight, departing Tue, Oct 21 from Key West to Charlotte, returning Tue, Oct 28, priced at $428 found 5 days ago
American Airlines
Tue, Nov 18 - Thu, Nov 20
EYW
Key West
CLT
Charlotte
$428 Roundtrip, found 5 days ago
$428
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, Nov 18 from Key West to Charlotte, returning Thu, Nov 20, priced at $428 found 5 days ago
Spirit Airlines
Thu, Jan 8 - Tue, Jan 13
EYW
Key West
CLT
Charlotte
$430 Roundtrip, found 3 days ago
$430
Roundtrip
found 3 days ago
Select Spirit Airlines flight, departing Thu, Jan 8 from Key West to Charlotte, returning Tue, Jan 13, priced at $430 found 3 days ago
Delta
Fri, Oct 24 - Tue, Oct 28
EYW
Key West
CLT
Charlotte
$457 Roundtrip, found 5 days ago
$457
Roundtrip
found 5 days ago
Select Delta flight, departing Fri, Oct 24 from Key West to Charlotte, returning Tue, Oct 28, priced at $457 found 5 days ago
United
Thu, Sep 18 - Sun, Sep 21
EYW
Key West
CLT
Charlotte
$549 Roundtrip, found 1 day ago
$549
Roundtrip
found 1 day ago
Select United flight, departing Thu, Sep 18 from Key West to Charlotte, returning Sun, Sep 21, priced at $549 found 1 day ago

Find the cheapest month to fly from Key West (EYW) to Charlotte (CLT)

January is typically the cheapest month to fly

From $216 - $813 per traveler.

Graph displaying average flight prices per month

Alternative airports near Charlotte

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Charlotte-Douglas Intl. CLT. Cheapest and Closest option available. Average driving time to city center is 11 minutes. Flights from $573
CLT
Charlotte-Douglas Intl.
CheapestClosest
Average driving time to city center11 min
Flights from $573
Flights from Key West (EYW) to Charlotte (CLT)
Origin airport
Key West Intl.
Destination airport
Charlotte-Douglas Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$290
Distance
738 mi
Average flight time
2 hours 27 mins

Key West to Charlotte Flights

The cheapest times to fly from Key West to Charlotte

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Key West to Charlotte are during the month of January. You can find some of the cheapest flights from Key West to Charlotte with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Key West to Charlotte

Sunday is one of the best days to book for cheap flights from Key West to Charlotte: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Key West to Charlotte

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Key West to Charlotte in 2025. You can also book with separate airlines for your outbound and return journeys, from $123 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Key West to Charlotte flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Key West to Charlotte airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Key West Intl. Airport (EYW) to Charlotte-Douglas Intl. Airport (CLT) cost?
You can find affordable return tickets from Key West Intl. Airport (EYW) to Charlotte-Douglas Intl. Airport (CLT) starting from $579. Snag a seat and set off on your next adventure. This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a American Airlines flight leaving EYW on August 16 2025 and touching down at CLT. The price was last updated on July 23 2025 and has not changed since.
What is the cheapest month to fly from EYW to CLT?
The cheapest flights from EYW to CLT are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Key West Intl. Airport (EYW) to Charlotte-Douglas Intl. Airport (CLT)?
When heading out of Key West Intl. Airport (EYW), you can board a direct flight to Charlotte-Douglas Intl. Airport (CLT) with American Airlines.
What is the cheapest airline that flies from EYW to CLT?
With fares starting at $344 for a one-way flight from EYW to CLT, American Airlines is currently the cheapest carrier on this route. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from EYW on September 22 2025. Prices were last updated on July 23 2025 and have not changed since.
How many flights per day from Key West Intl. Airport (EYW) to Charlotte-Douglas Intl. Airport (CLT)?
Each day on average, 3 direct flights take off from Key West Intl. Airport (EYW) to Charlotte-Douglas Intl. Airport (CLT). Select the departure time that best fits your schedule.
What are the most popular departure times for flights from Key West Intl. Airport (EYW) to Charlotte-Douglas Intl. Airport (CLT)?
Flights between EYW and CLT tend to be busiest at 12 PM. For a more relaxed trip and possibly cheaper tickets, choose a time when demand is lower.
What day of the week has the most flights from EYW to CLT?
If you travel on a Friday, you'll get the biggest range of options for flights from Key West Intl. Airport (EYW) to Charlotte-Douglas Intl. Airport (CLT).
What is the earliest flight from Key West Intl. Airport (EYW) to Charlotte-Douglas Intl. Airport (CLT)?
Catch the earliest flight at around 8:09AM UTC-5, heading out of Key West Intl. Airport (EYW). You'll be in the air for approximately 2h 20m, landing at Charlotte-Douglas Intl. Airport (CLT) at approximately 10:29AM UTC-5.
How long does it take to fly from Key West Intl. Airport (EYW) to Charlotte-Douglas Intl. Airport (CLT)?
The average flight time from EYW to CLT is 2 hours and 20 minutes, covering a total distance of 740 mi.
What is the best time to fly from Key West Intl. Airport (EYW) to Charlotte-Douglas Intl. Airport (CLT)?
Opt for a flight from Key West Intl. Airport (EYW) to Charlotte-Douglas Intl. Airport (CLT) that takes off before 3 PM to reduce the likelihood of delays. Departures after this hour have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Charlotte from Key West Intl. Airport (EYW)?
If you're flying on a direct flight from Key West Intl. Airport (EYW) to Charlotte, Charlotte-Douglas Intl. Airport (CLT) is the only airport you can touch down at.
Is it cheaper to buy a plane ticket from Key West Intl. Airport (EYW) to Charlotte-Douglas Intl. Airport (CLT) last-minute?
Booking your flight from EYW to CLT right before your journey is typically more expensive. However, if there's some wiggle room with your departure times and dates, you could snag a cheap last-minute fare.
Is it cheaper to book an EYW to CLT flight and hotel package?
Compared with arranging flights and hotels separately, booking an EYW to CLT flight and hotel package with Expedia could lead to significant savings. What's more, having everything in one convenient place takes the hassle out of planning your trip. Just pick your flights and select from our wide range of hotels, then tailor your trip with extras like tours and car rentals.
Can I cancel or change the date of my flight from Key West Intl. Airport (EYW) to Charlotte-Douglas Intl. Airport (CLT)?
It's usually possible to cancel or reschedule your EYW to CLT flight. However, if the booking was made more than 24 hours ago, additional fees may apply. Check your airline's policies in your itinerary to see what changes are allowed and if any costs are involved. You'll also find more details on our Customer Service portal.

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