$255 Cheap Flights from Florence (FLO) to Greenville (GSP)

View $255 flight on Fri, Nov 7, 2025Opens in a new window

Popular airlines from Florence, SC (FLO-Florence Regional) to Greenville-Spartanburg Intl. Airport (GSP)

Cheap Flights from Florence to Greenville (FLO-GSP)

Prices were available within the past 7 days and start at $255 for one-way flights and $447 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Sat, Jan 24 - Tue, Feb 10
FLO
Florence
GSP
Greenville
$447 Roundtrip, found 9 hours ago
$447
Roundtrip
found 9 hours ago
Select American Airlines flight, departing Sat, Jan 24 from Florence to Greenville, returning Tue, Feb 10, priced at $447 found 9 hours ago
American Airlines
Sun, Jan 18 - Wed, Feb 4
FLO
Florence
GSP
Greenville
$452 Roundtrip, found 9 hours ago
$452
Roundtrip
found 9 hours ago
Select American Airlines flight, departing Sun, Jan 18 from Florence to Greenville, returning Wed, Feb 4, priced at $452 found 9 hours ago
American Airlines
Tue, Mar 3 - Tue, Mar 17
FLO
Florence
GSP
Greenville
$452 Roundtrip, found 18 hours ago
$452
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Tue, Mar 3 from Florence to Greenville, returning Tue, Mar 17, priced at $452 found 18 hours ago
American Airlines
Sat, Mar 7 - Tue, Mar 17
FLO
Florence
GSP
Greenville
$457 Roundtrip, found 18 hours ago
$457
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Sat, Mar 7 from Florence to Greenville, returning Tue, Mar 17, priced at $457 found 18 hours ago
American Airlines
Sat, Feb 7 - Sat, Feb 21
FLO
Florence
GSP
Greenville
$462 Roundtrip, found 9 hours ago
$462
Roundtrip
found 9 hours ago
Select American Airlines flight, departing Sat, Feb 7 from Florence to Greenville, returning Sat, Feb 21, priced at $462 found 9 hours ago
American Airlines
Fri, Jan 23 - Sat, Feb 7
FLO
Florence
GSP
Greenville
$466 Roundtrip, found 9 hours ago
$466
Roundtrip
found 9 hours ago
Select American Airlines flight, departing Fri, Jan 23 from Florence to Greenville, returning Sat, Feb 7, priced at $466 found 9 hours ago
American Airlines
Sun, Jan 25 - Tue, Feb 10
FLO
Florence
GSP
Greenville
$467 Roundtrip, found 9 hours ago
$467
Roundtrip
found 9 hours ago
Select American Airlines flight, departing Sun, Jan 25 from Florence to Greenville, returning Tue, Feb 10, priced at $467 found 9 hours ago
American Airlines
Tue, Mar 3 - Thu, Mar 19
FLO
Florence
GSP
Greenville
$467 Roundtrip, found 18 hours ago
$467
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Tue, Mar 3 from Florence to Greenville, returning Thu, Mar 19, priced at $467 found 18 hours ago
American Airlines
Sat, Feb 28 - Tue, Mar 17
FLO
Florence
GSP
Greenville
$471 Roundtrip, found 9 hours ago
$471
Roundtrip
found 9 hours ago
Select American Airlines flight, departing Sat, Feb 28 from Florence to Greenville, returning Tue, Mar 17, priced at $471 found 9 hours ago
American Airlines
Sun, Jan 18 - Fri, Jan 30
FLO
Florence
GSP
Greenville
$472 Roundtrip, found 9 hours ago
$472
Roundtrip
found 9 hours ago
Select American Airlines flight, departing Sun, Jan 18 from Florence to Greenville, returning Fri, Jan 30, priced at $472 found 9 hours ago
Flights from Florence (FLO) to Greenville (GSP)
Origin airport
Florence Regional
Destination airport
Greenville-Spartanburg Intl.
Airlines serving
American Airlines
Roundtrip price
$446
Distance
149 mi

Florence to Greenville Flights

The cheapest times to fly from Florence to Greenville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Florence to Greenville are during the month of January. You can find some of the cheapest flights from Florence to Greenville with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Florence to Greenville

Sunday is one of the best days to book for cheap flights from Florence to Greenville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Florence to Greenville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Florence to Greenville in 2025. You can also book with separate airlines for your outbound and return journeys, from $255 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Florence to Greenville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Florence to Greenville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Florence Regional Airport (FLO) to Greenville-Spartanburg Intl. Airport (GSP) cost?
Secure a cheap one-way flight from $255 or cheap return flight from $447 from Florence Regional Airport (FLO) to Greenville-Spartanburg Intl. Airport (GSP) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Florence Regional Airport (FLO) to Greenville-Spartanburg Intl. Airport (GSP)?
January is the cheapest month to fly from FLO to GSP. Planning your trip for the off-season is often the key to better flight prices.
What is the cheapest airline that flies from Florence Regional Airport (FLO) to Greenville-Spartanburg Intl. Airport (GSP)?
To find the cheapest airline flying from FLO to GSP, use Expedia's filter tool. Customize your search based on what matters most to you, such as preferred carriers and seat class. You can then sort your results by "Price (lowest to highest)" to list the most affordable options first.
How many flights per day from Florence Regional Airport (FLO) to Greenville-Spartanburg Intl. Airport (GSP)?
There are no daily direct flights available from Florence Regional Airport (FLO) to Greenville-Spartanburg Intl. Airport (GSP). But you can opt for flights with layovers. Filter your search results on Expedia to include one or more stops, and you'll be cruising above the clouds in no time.
What day of the week has the most flights from FLO to GSP?
Friday is usually the busiest day for flights, while Tuesday is often the quietest.* Just remember that flight schedules can change depending on various factors, including the season and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Florence Regional Airport (FLO) to Greenville-Spartanburg Intl. Airport (GSP)?
To reach Greenville-Spartanburg Intl. Airport (GSP) on time, choose a flight that leaves Florence Regional Airport (FLO) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Florence Regional Airport (FLO) to Greenville-Spartanburg Intl. Airport (GSP) last-minute?
Booking your flight from FLO to GSP shortly before your getaway is usually more expensive. But if you're flexible with your itinerary, you could bag a cheap last-minute fare.
Is it cheaper to book a FLO to GSP flight and hotel package?
Compared with arranging flights and hotels separately, booking a FLO to GSP flight and hotel package with Expedia could lead to significant savings. What's more, managing everything in one place takes the hassle out of planning your trip. Simply secure your flights and select from our wide range of stays, then personalize your trip with extras like tours and car rentals.
Can I cancel or change the date of my flight from Florence Regional Airport (FLO) to Greenville-Spartanburg Intl. Airport (GSP)?
If you booked your FLO to GSP flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of fare you purchased, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal for more details.

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*Available to One Key members.