$141 Cheap Flights from Guayaquil (GYE) to Columbus (CMH)

View $141 flight on Wed, Dec 10, 2025Opens in a new window

Popular airlines from Jose Joaquin de Olmedo Intl. Airport (GYE) to John Glenn Columbus Intl. Airport (CMH)

Cheap Flights from Guayaquil to Columbus (GYE-CMH)

Prices were available within the past 7 days and start at $141 for one-way flights and $295 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Spirit Airlines
Tue, Dec 9 - Wed, Jan 21
GYE
Guayaquil
CMH
Columbus
$295 Roundtrip, found 6 days ago
$295
Roundtrip
found 6 days ago
Select Spirit Airlines flight, departing Tue, Dec 9 from Guayaquil to Columbus, returning Wed, Jan 21, priced at $295 found 6 days ago
Spirit Airlines
Wed, Dec 17 - Wed, Jan 21
GYE
Guayaquil
CMH
Columbus
$368 Roundtrip, found 6 days ago
$368
Roundtrip
found 6 days ago
Select Spirit Airlines flight, departing Wed, Dec 17 from Guayaquil to Columbus, returning Wed, Jan 21, priced at $368 found 6 days ago
Spirit Airlines
Thu, Dec 25 - Sun, Jan 11
GYE
Guayaquil
CMH
Columbus
$375 Roundtrip, found 3 days ago
$375
Roundtrip
found 3 days ago
Select Spirit Airlines flight, departing Thu, Dec 25 from Guayaquil to Columbus, returning Sun, Jan 11, priced at $375 found 3 days ago
Spirit Airlines
Thu, Feb 19 - Wed, Feb 25
GYE
Guayaquil
CMH
Columbus
$412 Roundtrip, found 4 days ago
$412
Roundtrip
found 4 days ago
Select Spirit Airlines flight, departing Thu, Feb 19 from Guayaquil to Columbus, returning Wed, Feb 25, priced at $412 found 4 days ago
Spirit Airlines
Tue, Dec 23 - Thu, Jan 22
GYE
Guayaquil
CMH
Columbus
$417 Roundtrip, found 6 days ago
$417
Roundtrip
found 6 days ago
Select Spirit Airlines flight, departing Tue, Dec 23 from Guayaquil to Columbus, returning Thu, Jan 22, priced at $417 found 6 days ago
Spirit Airlines
Thu, Dec 25 - Sun, Jan 11
GYE
Guayaquil
CMH
Columbus
$434 Roundtrip, found 3 days ago
$434
Roundtrip
found 3 days ago
Select Spirit Airlines flight, departing Thu, Dec 25 from Guayaquil to Columbus, returning Sun, Jan 11, priced at $434 found 3 days ago
avianca
Thu, Feb 19 - Wed, Feb 25
GYE
Guayaquil
CMH
Columbus
$555 Roundtrip, found 4 days ago
$555
Roundtrip
found 4 days ago
Select avianca flight, departing Thu, Feb 19 from Guayaquil to Columbus, returning Wed, Feb 25, priced at $555 found 4 days ago
United
Thu, Feb 19 - Wed, Feb 25
GYE
Guayaquil
CMH
Columbus
$556 Roundtrip, found 4 days ago
$556
Roundtrip
found 4 days ago
Select United flight, departing Thu, Feb 19 from Guayaquil to Columbus, returning Wed, Feb 25, priced at $556 found 4 days ago
Copa
Thu, Feb 19 - Wed, Feb 25
GYE
Guayaquil
CMH
Columbus
$568 Roundtrip, found 4 days ago
$568
Roundtrip
found 4 days ago
Select Copa flight, departing Thu, Feb 19 from Guayaquil to Columbus, returning Wed, Feb 25, priced at $568 found 4 days ago
American Airlines
Wed, Mar 18 - Sun, May 3
GYE
Guayaquil
CMH
Columbus
$736 Roundtrip, found 6 hours ago
$736
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Wed, Mar 18 from Guayaquil to Columbus, returning Sun, May 3, priced at $736 found 6 hours ago
Flights from Guayaquil (GYE) to Columbus (CMH)
Origin airport
Jose Joaquin de Olmedo Intl.
Destination airport
John Glenn Columbus Intl.
Airlines serving
American Airlines, Delta, LATAM Airlines Group, United, avianca
Roundtrip price
$295
Distance
2918 mi

Guayaquil to Columbus Flights

The cheapest times to fly from Guayaquil to Columbus

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Guayaquil to Columbus are during the month of December. You can find some of the cheapest flights from Guayaquil to Columbus with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Guayaquil to Columbus

Sunday is one of the best days to book for cheap flights from Guayaquil to Columbus: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Guayaquil to Columbus

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Guayaquil to Columbus in 2025. You can also book with separate airlines for your outbound and return journeys, from $141 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Guayaquil to Columbus flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Guayaquil to Columbus airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Jose Joaquin de Olmedo Intl. Airport (GYE) to John Glenn Columbus Intl. Airport (CMH) cost?
Grab a cheap one-way flight from $141 or cheap return flight from $295 from Jose Joaquin de Olmedo Intl. Airport (GYE) to John Glenn Columbus Intl. Airport (CMH) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Jose Joaquin de Olmedo Intl. Airport (GYE) to John Glenn Columbus Intl. Airport (CMH)?
December is the most affordable month to fly from GYE to CMH. Avoiding peak travel times is often the key to better flight prices.
What is the cheapest airline that flies from Jose Joaquin de Olmedo Intl. Airport (GYE) to John Glenn Columbus Intl. Airport (CMH)?
Expedia's filter tool lets you easily compare different airlines, travel time and fares all in one place. Tailor the search to your trip, then sort by "Price (lowest to highest)" to find the carrier with the cheapest GYE to CMH flight.
How many flights per day from Jose Joaquin de Olmedo Intl. Airport (GYE) to John Glenn Columbus Intl. Airport (CMH)?
There aren't any daily nonstop flights from Jose Joaquin de Olmedo Intl. Airport (GYE) to John Glenn Columbus Intl. Airport (CMH). But you can opt for flights with layovers. Filter your search on Expedia to include one or two stops, and you'll be soaring above the clouds in no time at all.
What day of the week has the most flights from GYE to CMH?
Friday is typically the busiest day for flights, while Tuesday is often the quietest.* Just remember that flight schedules can change based on various factors, including the carrier and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Jose Joaquin de Olmedo Intl. Airport (GYE) to John Glenn Columbus Intl. Airport (CMH)?
To arrive at John Glenn Columbus Intl. Airport (CMH) on schedule, opt for a flight that leaves Jose Joaquin de Olmedo Intl. Airport (GYE) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Jose Joaquin de Olmedo Intl. Airport (GYE) to John Glenn Columbus Intl. Airport (CMH) last-minute?
Last-minute bookings from GYE to CMH are generally more expensive. For the lowest prices, start searching for flights well ahead of time. That said, if your travel plans are flexible, you may score a cheap ticket right before you leave.
Is it cheaper to book a GYE to CMH flight and hotel package?
Securing a GYE to CMH flight and hotel package is typically cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your trip in one place. Pick from our impressive range of accommodations and then add car rentals, flights and activities to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Jose Joaquin de Olmedo Intl. Airport (GYE) to John Glenn Columbus Intl. Airport (CMH)?
Usually, it's possible to cancel or reschedule your GYE to CMH flight. However, if it's been more than 24 hours since booking, additional charges may apply. Check your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find more details on our Customer Service portal.

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*Available to One Key members.