$719 Cheap Flights from Houston (HOU) to Panama City (PTY)

View $719 flight on Mon, Dec 29, 2025Opens in a new window

Popular airlines from Houston William Hobby Airport (HOU) to Tocumen Intl. Airport (PTY)

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Cheap Flights from Houston to Panama City (HOU-PTY)

Prices were available within the past 7 days and start at $719 for one-way flights and $753 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Sun, Aug 31 - Tue, Sep 9
HOU
Houston
PTY
Panama City
$753 Roundtrip, found 15 hours ago
$753
Roundtrip
found 15 hours ago
Select Delta flight, departing Sun, Aug 31 from Houston to Panama City, returning Tue, Sep 9, priced at $753 found 15 hours ago

Find the cheapest month to fly from Houston (HOU) to Panama City (PTY)

January is typically the cheapest month to fly

From $347 - $998 per traveler.

Graph displaying average flight prices per month

Alternative airports near Panama City

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Tocumen Intl. PTY. Cheapest option available. Average driving time to city center is 16 minutes. Flights from $807
PTY
Tocumen Intl.
Cheapest
Average driving time to city center16 min
Flights from $807
Flights from Houston (IAH) to Panama City (PTY)
Origin airport
George Bush Intercontinental
Destination airport
Tocumen Intl.
Airlines serving
American Airlines, Delta
Roundtrip price
$645
Distance
1775 mi

Houston to Panama City Flights

The cheapest times to fly from Houston to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Houston to Panama City are during the month of August. You can find some of the cheapest flights from Houston to Panama City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Houston to Panama City

Sunday is one of the best days to book for cheap flights from Houston to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Houston to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Houston to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from $719 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Houston to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Houston to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from William P. Hobby Airport (HOU) to Tocumen Intl. Airport (PTY) cost?
Discover the latest flight deals from HOU to PTY by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from HOU to PTY?
The cheapest flights from HOU to PTY are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from William P. Hobby Airport (HOU) to Tocumen Intl. Airport (PTY)?
You can't fly direct to Tocumen Intl. Airport (PTY) from Houston, TX (HOU-William P. Hobby). However, you can seamlessly travel to Panama City without any layovers by departing from George Bush Intercontinental Airport (IAH).
What is the cheapest airline that flies from HOU to PTY?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll take you from HOU to PTY. Sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from William P. Hobby Airport (HOU) to Tocumen Intl. Airport (PTY)?
You'll need to catch a flight with a layover if you're traveling from William P. Hobby Airport (HOU) to Tocumen Intl. Airport (PTY). Direct flights don't operate daily on this route. However, simply filter your search to include one or two stops to discover an option that works for you.
What day of the week has the most flights from HOU to PTY?
Friday is generally the busiest day for flights, while Tuesday tends to be the quietest.* Just remember that flight schedules can change based on a range of factors, including the season and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from William P. Hobby Airport (HOU) to Tocumen Intl. Airport (PTY)?
To arrive at Tocumen Intl. Airport (PTY) on time, book a flight that leaves William P. Hobby Airport (HOU) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from William P. Hobby Airport (HOU) to Tocumen Intl. Airport (PTY) last-minute?
Holding off until just before your departure to book a flight from HOU to PTY generally means paying more. While you may come across some last-minute offers, they're not always guaranteed. Allow some flexibility in your schedule for the best chance of landing a bargain.
Is it cheaper to book a HOU to PTY flight and hotel package?
Compared with arranging flights and hotels separately, booking a HOU to PTY flight and hotel package with Expedia could lead to significant savings. What's more, having it all in one place will take the hassle out of travel planning. Simply secure your flights and select from our wide range of stays, then personalize your trip with other add-ons like car rentals and activities.
Can I cancel or change the date of my flight from William P. Hobby Airport (HOU) to Tocumen Intl. Airport (PTY)?
Usually, it's possible to reschedule or cancel your HOU to PTY flight. However, if the booking was made more than 24 hours ago, additional charges may apply. Check your airline's policies in your itinerary to see what changes are possible and if any costs are involved. You'll also find further details on our Customer Service portal.

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*Available to One Key members.