$312 Cheap Flights from Islip (ISP) to Guayaquil (GYE)

View $312 flight on Thu, Aug 21, 2025Opens in a new window

Popular airlines from MacArthur Airport (ISP) to Jose Joaquin de Olmedo Intl. Airport (GYE)

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 30% on select hotels after you book a flight*
  • one key icon

    Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Cheap Flights from Islip to Guayaquil (ISP-GYE)

Prices were available within the past 7 days and start at $312 for one-way flights and $444 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

JetBlue Airways
Wed, Sep 24 - Sun, Oct 5
ISP
Islip
GYE
Guayaquil
$444 Roundtrip, found 3 days ago
$444
Roundtrip
found 3 days ago
Select JetBlue Airways flight, departing Wed, Sep 24 from Islip to Guayaquil, returning Sun, Oct 5, priced at $444 found 3 days ago
JetBlue Airways
Fri, Sep 26 - Tue, Oct 14
ISP
Islip
GYE
Guayaquil
$453 Roundtrip, found 3 days ago
$453
Roundtrip
found 3 days ago
Select JetBlue Airways flight, departing Fri, Sep 26 from Islip to Guayaquil, returning Tue, Oct 14, priced at $453 found 3 days ago
JetBlue Airways
Mon, Sep 29 - Thu, Oct 16
ISP
Islip
GYE
Guayaquil
$454 Roundtrip, found 3 days ago
$454
Roundtrip
found 3 days ago
Select JetBlue Airways flight, departing Mon, Sep 29 from Islip to Guayaquil, returning Thu, Oct 16, priced at $454 found 3 days ago
JetBlue Airways
Mon, Sep 29 - Tue, Oct 14
ISP
Islip
GYE
Guayaquil
$464 Roundtrip, found 3 days ago
$464
Roundtrip
found 3 days ago
Select JetBlue Airways flight, departing Mon, Sep 29 from Islip to Guayaquil, returning Tue, Oct 14, priced at $464 found 3 days ago
JetBlue Airways
Wed, Sep 3 - Thu, Sep 18
ISP
Islip
GYE
Guayaquil
$474 Roundtrip, found 3 days ago
$474
Roundtrip
found 3 days ago
Select JetBlue Airways flight, departing Wed, Sep 3 from Islip to Guayaquil, returning Thu, Sep 18, priced at $474 found 3 days ago
JetBlue Airways
Thu, Aug 21 - Tue, Aug 26
ISP
Islip
GYE
Guayaquil
$479 Roundtrip, found 2 hours ago
$479
Roundtrip
found 2 hours ago
Select JetBlue Airways flight, departing Thu, Aug 21 from Islip to Guayaquil, returning Tue, Aug 26, priced at $479 found 2 hours ago
JetBlue Airways
Tue, Sep 2 - Thu, Sep 18
ISP
Islip
GYE
Guayaquil
$484 Roundtrip, found 3 days ago
$484
Roundtrip
found 3 days ago
Select JetBlue Airways flight, departing Tue, Sep 2 from Islip to Guayaquil, returning Thu, Sep 18, priced at $484 found 3 days ago
JetBlue Airways
Wed, Oct 1 - Thu, Oct 16
ISP
Islip
GYE
Guayaquil
$489 Roundtrip, found 3 days ago
$489
Roundtrip
found 3 days ago
Select JetBlue Airways flight, departing Wed, Oct 1 from Islip to Guayaquil, returning Thu, Oct 16, priced at $489 found 3 days ago
JetBlue Airways
Wed, Sep 17 - Sun, Sep 28
ISP
Islip
GYE
Guayaquil
$496 Roundtrip, found 3 days ago
$496
Roundtrip
found 3 days ago
Select JetBlue Airways flight, departing Wed, Sep 17 from Islip to Guayaquil, returning Sun, Sep 28, priced at $496 found 3 days ago
JetBlue Airways
Wed, Oct 1 - Tue, Oct 14
ISP
Islip
GYE
Guayaquil
$499 Roundtrip, found 3 days ago
$499
Roundtrip
found 3 days ago
Select JetBlue Airways flight, departing Wed, Oct 1 from Islip to Guayaquil, returning Tue, Oct 14, priced at $499 found 3 days ago

Alternative airports near Guayaquil

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Jose Joaquin de Olmedo Intl. GYE. Cheapest and Closest option available. Average driving time to city center is 9 minutes. Flights from $771
GYE
Jose Joaquin de Olmedo Intl.
CheapestClosest
Average driving time to city center9 min
Flights from $771
Flights from Islip (ISP) to Guayaquil (GYE)
Origin airport
MacArthur
Destination airport
Jose Joaquin de Olmedo Intl.
Airlines serving
JetBlue Airways
Roundtrip price
$443
Distance
2997 mi

Islip to Guayaquil Flights

The cheapest times to fly from Islip to Guayaquil

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Islip to Guayaquil are during the month of September. You can find some of the cheapest flights from Islip to Guayaquil with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Islip to Guayaquil

Sunday is one of the best days to book for cheap flights from Islip to Guayaquil: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Islip to Guayaquil

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Islip to Guayaquil in 2025. You can also book with separate airlines for your outbound and return journeys, from $312 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Islip to Guayaquil flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Islip to Guayaquil airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from MacArthur Airport (ISP) to Jose Joaquin de Olmedo Intl. Airport (GYE) cost?
Discover the latest flight deals from ISP to GYE by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from ISP to GYE?
The cheapest flights from ISP to GYE are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from MacArthur Airport (ISP) to Jose Joaquin de Olmedo Intl. Airport (GYE)?
Direct flights aren't available from Islip, NY (ISP-MacArthur) to Jose Joaquin de Olmedo Intl. Airport (GYE). However, you can find other airports that have nonstop flights. Board your plane at John F. Kennedy Intl. Airport (JFK) and travel straight to Guayaquil without any detours.
What is the cheapest airline that flies from ISP to GYE?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll take you from ISP to GYE. Sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from MacArthur Airport (ISP) to Jose Joaquin de Olmedo Intl. Airport (GYE)?
There are no daily nonstop flights departing from MacArthur Airport (ISP) to Jose Joaquin de Olmedo Intl. Airport (GYE). But you can opt for flights with layovers. Filter your search results on Expedia to include one or two stops, and you'll be on your way in no time.
What day of the week has the most flights from ISP to GYE?
Generally you'll find the widest variety of flight choices on a Friday. Tuesdays are often the quietest.* However, this can vary depending on the season, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from MacArthur Airport (ISP) to Jose Joaquin de Olmedo Intl. Airport (GYE)?
Select a flight from MacArthur Airport (ISP) to Jose Joaquin de Olmedo Intl. Airport (GYE) that leaves before 3 PM to reduce the risk of cancellations. Departures later than this are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from MacArthur Airport (ISP) to Jose Joaquin de Olmedo Intl. Airport (GYE) last-minute?
Last-minute fares from ISP to GYE are generally more expensive. To lock in the lowest prices, start searching for flights well ahead of time. That said, if you're flexible with your travel dates, you may land a cheap ticket just before your departure.
Is it cheaper to book an ISP to GYE flight and hotel package?
Compared with arranging hotels and flights separately, booking an ISP to GYE flight and hotel package with Expedia could lead to significant savings. What's more, having everything in one place takes the hassle out of travel planning. Just pick your flights and choose from our extensive range of hotels, then customize your trip with other add-ons like tours, activities and car rentals.
Can I cancel or change the date of my flight from MacArthur Airport (ISP) to Jose Joaquin de Olmedo Intl. Airport (GYE)?
In most cases, you can cancel or modify your ISP to GYE flight. However, there may be additional fees, especially if you made your booking over 24 hours ago. Double-check your itinerary for the airline's fees and policies on flight changes, or if you'd like further information, go to our Customer Service portal.

Explore a world of travel with Expedia

Islip nearby Airports

New York

LaGuardia to Guayaquil
$362.97
John F. Kennedy Intl. to Guayaquil
$375.23

White Plains

Westchester County to Guayaquil
$443.23
*Available to One Key members.