$331 Cheap Flights from Lisbon (LIS) to Medellín (MDE)

View $331 flight on Thu, Sep 11, 2025Opens in a new window

Popular airlines from Humberto Delgado Airport (LIS) to Jose Maria Cordova Intl. Airport (MDE)

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Cheap Flights from Lisbon to Medellín (LIS-MDE)

Prices were available within the past 7 days and start at $331 for one-way flights and $684 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

TAP Portugal
Wed, Aug 27 - Fri, Sep 19
LIS
Lisbon
MDE
Medellin
$684 Roundtrip, found 2 days ago
$684
Roundtrip
found 2 days ago
Select TAP Portugal flight, departing Wed, Aug 27 from Lisbon to Medellin, returning Fri, Sep 19, priced at $684 found 2 days ago
TAP Portugal
Fri, Sep 5 - Wed, Sep 17
LIS
Lisbon
MDE
Medellin
$686 Roundtrip, found 3 days ago
$686
Roundtrip
found 3 days ago
Select TAP Portugal flight, departing Fri, Sep 5 from Lisbon to Medellin, returning Wed, Sep 17, priced at $686 found 3 days ago
TAP Portugal
Mon, Sep 1 - Fri, Sep 19
LIS
Lisbon
MDE
Medellin
$691 Roundtrip, found 2 days ago
$691
Roundtrip
found 2 days ago
Select TAP Portugal flight, departing Mon, Sep 1 from Lisbon to Medellin, returning Fri, Sep 19, priced at $691 found 2 days ago
TAP Portugal
Fri, Sep 5 - Wed, Sep 17
LIS
Lisbon
MDE
Medellin
$693 Roundtrip, found 3 days ago
$693
Roundtrip
found 3 days ago
Select TAP Portugal flight, departing Fri, Sep 5 from Lisbon to Medellin, returning Wed, Sep 17, priced at $693 found 3 days ago
TAP Portugal
Thu, Aug 21 - Fri, Sep 5
LIS
Lisbon
MDE
Medellin
$697 Roundtrip, found 2 days ago
$697
Roundtrip
found 2 days ago
Select TAP Portugal flight, departing Thu, Aug 21 from Lisbon to Medellin, returning Fri, Sep 5, priced at $697 found 2 days ago
TAP Portugal
Tue, Oct 21 - Fri, Oct 31
LIS
Lisbon
MDE
Medellin
$698 Roundtrip, found 3 days ago
$698
Roundtrip
found 3 days ago
Select TAP Portugal flight, departing Tue, Oct 21 from Lisbon to Medellin, returning Fri, Oct 31, priced at $698 found 3 days ago
avianca
Mon, Nov 10 - Tue, Nov 25
LIS
Lisbon
MDE
Medellin
$811 Roundtrip, found 3 days ago
$811
Roundtrip
found 3 days ago
Select avianca flight, departing Mon, Nov 10 from Lisbon to Medellin, returning Tue, Nov 25, priced at $811 found 3 days ago
KLM
Thu, Nov 20 - Sun, Nov 30
LIS
Lisbon
MDE
Medellin
$944 Roundtrip, found 3 days ago
$944
Roundtrip
found 3 days ago
Select KLM flight, departing Thu, Nov 20 from Lisbon to Medellin, returning Sun, Nov 30, priced at $944 found 3 days ago
Air Europa
Mon, Nov 17 - Sat, Nov 22
LIS
Lisbon
MDE
Medellin
$956 Roundtrip, found 1 day ago
$956
Roundtrip
found 1 day ago
Select Air Europa flight, departing Mon, Nov 17 from Lisbon to Medellin, returning Sat, Nov 22, priced at $956 found 1 day ago
Lufthansa
Tue, Nov 25 - Tue, Dec 9
LIS
Lisbon
MDE
Medellin
$988 Roundtrip, found 3 days ago
$988
Roundtrip
found 3 days ago
Select Lufthansa flight, departing Tue, Nov 25 from Lisbon to Medellin, returning Tue, Dec 9, priced at $988 found 3 days ago

Alternative airports near Medellín

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Jose Maria Cordova Intl. MDE. Cheapest option available. Average driving time to city center is 29 minutes. Flights from $983
MDE
Jose Maria Cordova Intl.
Cheapest
Average driving time to city center29 min
Flights from $983
Flights from Lisbon (LIS) to Medellín (MDE)
Origin airport
Humberto Delgado
Destination airport
José María Córdova Intl.
Airlines serving
Air Canada, Air Europa, American Airlines, Iberia, KLM, LATAM Airlines Group, TAP Portugal, United
Roundtrip price
$683
Distance
4679 mi

Lisbon to Medellín Flights

The cheapest times to fly from Lisbon to Medellín

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Lisbon to Medellín are during the month of August. You can find some of the cheapest flights from Lisbon to Medellín with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Lisbon to Medellín

Sunday is one of the best days to book for cheap flights from Lisbon to Medellín: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Lisbon to Medellín

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Lisbon to Medellín in 2025. You can also book with separate airlines for your outbound and return journeys, from $331 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Lisbon to Medellín flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Lisbon to Medellín airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Humberto Delgado Airport (LIS) to Jose Maria Cordova Intl. Airport (MDE) cost?
Discover the latest flight deals from LIS to MDE by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from LIS to MDE?
The cheapest flights from LIS to MDE are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from LIS to MDE?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll take you from LIS to MDE. Sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from Humberto Delgado Airport (LIS) to Jose Maria Cordova Intl. Airport (MDE)?
You'll need to catch a flight with a layover if you're traveling from Humberto Delgado Airport (LIS) to Jose Maria Cordova Intl. Airport (MDE). Direct flights don't operate daily on this route. However, simply filter your search to include one or more stops to find the best option for your trip.
What day of the week has the most flights from LIS to MDE?
You'll usually find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can vary from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Humberto Delgado Airport (LIS) to Jose Maria Cordova Intl. Airport (MDE)?
To arrive at Jose Maria Cordova Intl. Airport (MDE) on time, book a flight that leaves Humberto Delgado Airport (LIS) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Humberto Delgado Airport (LIS) to Jose Maria Cordova Intl. Airport (MDE) last-minute?
Holding off until right before your break to book your flight from LIS to MDE often results in higher prices. While you might find some last-minute discounts, they aren't always guaranteed. Keep your travel schedule open for a better chance of snagging a bargain.
Is it cheaper to book a LIS to MDE flight and hotel package?
Securing a LIS to MDE flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your trip all in one place. Choose from our wide range of hotels and then add car rentals, flights and activities to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Humberto Delgado Airport (LIS) to Jose Maria Cordova Intl. Airport (MDE)?
Typically, you can modify or cancel your LIS to MDE flight. However, there may be additional charges, especially if you booked more than 24 hours ago. Double-check your itinerary for the airline's fees and policies on flight changes, or if you want more details, go to our Customer Service portal.

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*Available to One Key members.